STAT4 Transcription Factor

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  Subject Areas on Research

  • Deletion of a conserved cis-element in the Ifng locus highlights the role of acute histone acetylation in modulating inducible gene transcription. 
  • Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage. 
  • Modular utilization of distal cis-regulatory elements controls Ifng gene expression in T cells activated by distinct stimuli. 
  • Role of T-bet in commitment of TH1 cells before IL-12-dependent selection.