Synaptosomal-Associated Protein 25

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  Subject Areas on Research

  • Ca2+-dependent synaptotagmin binding to SNAP-25 is essential for Ca2+-triggered exocytosis. 
  • Disruption of syntaxin-mediated protein interactions blocks neurotransmitter secretion. 
  • Effects of source of DNA on genotyping success rates and allele percentages in the Preschoolers with Attention-Deficit/Hyperactivity Disorder Treatment Study (PATS). 
  • Identification of a novel repressive element that contributes to neuron-specific gene expression. 
  • Pharmacogenetics of methylphenidate response in preschoolers with ADHD. 
  • Snare protein expression and adenoviral transfection of amphicrine AR42J. 
  • Specificity and regulation of a synaptic vesicle docking complex. 
  • Synaptic vesicle exocytosis: molecules and models. 
  • The 25 kDa synaptosomal-associated protein SNAP-25 is the major methionine-rich polypeptide in rapid axonal transport and a major substrate for palmitoylation in adult CNS. 
  • The Kv2.1 channels mediate neuronal apoptosis induced by excitotoxicity. 
  • The SNAP-25 gene may be associated with clinical response and weight gain in antipsychotic treatment of schizophrenia.