Synaptotagmins

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  Subject Areas on Research

  • Ca2+-dependent synaptotagmin binding to SNAP-25 is essential for Ca2+-triggered exocytosis. 
  • Chordin is required for neural but not axial development in sea urchin embryos. 
  • Differential expression of synaptic proteins in the frontal and temporal cortex of elderly subjects with mild cognitive impairment. 
  • Dual roles of the C2B domain of synaptotagmin I in synchronizing Ca2+-dependent neurotransmitter release. 
  • How does calcium trigger neurotransmitter release? 
  • Inhibition of neurotransmitter release by C2-domain peptides implicates synaptotagmin in exocytosis. 
  • Molecular pathways for presynaptic calcium signaling. 
  • Synaptic vesicle exocytosis: molecules and models. 
  • Synaptotagmin I synchronizes transmitter release in mouse hippocampal neurons. 
  • Synaptotagmin IX regulates Ca2+-dependent secretion in PC12 cells. 
  • Synaptotagmin and neurotransmitter release. 
  • Syntaxin: a synaptic protein implicated in docking of synaptic vesicles at presynaptic active zones. 
  • [Studying pathogenesis of Alzheimer's disease in a Drosophila melanogaster model: human APP overexpression in the brain of transgenic flies leads to deficit of the synaptic protein synaptotagmin].