CREB-Binding Protein
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Subject Areas on Research
- A c-Fos- and E1A-interacting component of the tissue factor basal promoter complex mediates synergistic activation of transcription by transforming growth factor-beta1.
- A mechanism of COOH-terminal binding protein-mediated repression.
- A novel TLR4-mediated signaling pathway leading to IL-6 responses in human bladder epithelial cells.
- A stimulus-specific role for CREB-binding protein (CBP) in T cell receptor-activated tumor necrosis factor alpha gene expression.
- Adaptor proteins in lymphocyte activation.
- Amphipathic small molecules mimic the binding mode and function of endogenous transcription factors.
- BDNF-mediated cerebellar granule cell development is impaired in mice null for CaMKK2 or CaMKIV.
- CREB-binding protein regulates apoptosis and growth of HMECs grown in reconstituted ECM via laminin-5.
- CXCL12 prolongs naive CD4+ T lymphocytes survival via activation of PKA, CREB and Bcl2 and BclXl up-regulation.
- Calmodulin-dependent kinase IV links Toll-like receptor 4 signaling with survival pathway of activated dendritic cells.
- Case-control association study of 14 variants of CREB1, CREBBP and CREM on diagnosis and treatment outcome in major depressive disorder and bipolar disorder.
- Chromatin-related properties of CBP fused to MLL generate a myelodysplastic-like syndrome that evolves into myeloid leukemia.
- CoA synthase regulates mitotic fidelity via CBP-mediated acetylation.
- Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease.
- Consensus and variant cAMP-regulated enhancers have distinct CREB-binding properties.
- Distinct roles of the co-activators p300 and CBP in retinoic-acid-induced F9-cell differentiation.
- Duration of nuclear NF-kappaB action regulated by reversible acetylation.
- Early differential elevation and persistence of phosphorylated cAMP-response element binding protein (p-CREB) in the central nervous system of hens treated with diisopropyl phosphorofluoridate, an OPIDN-causing compound.
- Elevated mu-opioid receptor expression in the nucleus of the solitary tract accompanies attenuated withdrawal signs after chronic low dose naltrexone in opiate-dependent rats.
- Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling.
- Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP.
- Histone deacetylase 3 binds to and regulates the GCMa transcription factor.
- Hormone-dependent interaction between the amino- and carboxyl-terminal domains of progesterone receptor in vitro and in vivo.
- Inhibition of Ca²⁺/calmodulin-dependent protein kinase kinase 2 stimulates osteoblast formation and inhibits osteoclast differentiation.
- Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation.
- Kappa-Opioid Antagonists for Psychiatric Disorders: From Bench to Clinical Trials.
- Lineage-specific signaling in melanocytes. C-kit stimulation recruits p300/CBP to microphthalmia.
- Mutations of the Sonic Hedgehog Pathway Underlie Hypothalamic Hamartoma with Gelastic Epilepsy.
- Novel mutations target distinct subgroups of medulloblastoma.
- Nuclear protein CBP is a coactivator for the transcription factor CREB.
- Possible influence of CREB1, CREBBP and CREM variants on diagnosis and treatment outcome in patients with schizophrenia.
- Recruitment of CREB binding protein is sufficient for CREB-mediated gene activation.
- Role of T-bet in commitment of TH1 cells before IL-12-dependent selection.
- The glucocorticoid receptor interacting protein 1 (GRIP1) localizes in discrete nuclear foci that associate with ND10 bodies and are enriched in components of the 26S proteasome.
- The transcriptional integrator CREB-binding protein mediates positive cross talk between nuclear hormone receptors and the hematopoietic bZip protein p45/NF-E2.
- Transient hypoxia stimulates mitochondrial biogenesis in brain subcortex by a neuronal nitric oxide synthase-dependent mechanism.