Basic-Leucine Zipper Transcription Factors
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Subject Areas on Research
- A conserved domain of the viviparous-1 gene product enhances the DNA binding activity of the bZIP protein EmBP-1 and other transcription factors.
- A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes.
- A validated regulatory network for Th17 cell specification.
- A viral microRNA functions as an orthologue of cellular miR-155.
- BATF Modulates the Th2 Locus Control Region and Regulates CD4+ T Cell Fate during Antihelminth Immunity.
- Cardiac glutaminolysis: a maladaptive cancer metabolism pathway in the right ventricle in pulmonary hypertension.
- Cell biology: How to combat stress.
- Characterization of murine BATF: a negative regulator of activator protein-1 activity in the thymus.
- Complexity of CNC transcription factors as revealed by gene targeting of the Nrf3 locus.
- Differential binding of c-Myc and Max to nucleosomal DNA.
- Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism.
- Expression profiling of the developing and mature Nrl-/- mouse retina: identification of retinal disease candidates and transcriptional regulatory targets of Nrl.
- Histone H1 enhances the DNA binding activity of the transcription factor EmBP-1.
- Hos2p/Set3p deacetylase complex signals secretory stress through the Mpk1p cell integrity pathway.
- ICECREAM: randomised phase II study of cetuximab alone or in combination with irinotecan in patients with metastatic colorectal cancer with either KRAS, NRAS, BRAF and PI3KCA wild type, or G13D mutated tumours.
- IRE1/bZIP60-mediated unfolded protein response plays distinct roles in plant immunity and abiotic stress responses.
- Identification and characterization of upstream open reading frames (uORF) in the 5' untranslated regions (UTR) of genes in Saccharomyces cerevisiae.
- In vivo interaction between NPR1 and transcription factor TGA2 leads to salicylic acid-mediated gene activation in Arabidopsis.
- Inactivation of the tumor suppressor genes causing the hereditary syndromes predisposing to head and neck cancer via promoter hypermethylation in sporadic head and neck cancers.
- Inherited variants in mitochondrial biogenesis genes may influence epithelial ovarian cancer risk.
- Mechanistic basis for the failure of cone transducin to translocate: why cones are never blinded by light.
- MicroRNA-31 controls G protein alpha-13 (GNA13) expression and cell invasion in breast cancer cells.
- Mutation screening of patients with Leber Congenital Amaurosis or the enhanced S-Cone Syndrome reveals a lack of sequence variations in the NRL gene.
- Mxi1-0, an alternatively transcribed Mxi1 isoform, is overexpressed in glioblastomas.
- NPR1 modulates cross-talk between salicylate- and jasmonate-dependent defense pathways through a novel function in the cytosol.
- Opposite orientations of DNA bending by c-Myc and Max.
- Photoreceptor-specific nuclear receptor NR2E3 functions as a transcriptional activator in rod photoreceptors.
- Protein sequestration generates a flexible ultrasensitive response in a genetic network.
- Regulation of systemic acquired resistance by NPR1 and its partners.
- Retinoid-related orphan nuclear receptor RORbeta is an early-acting factor in rod photoreceptor development.
- Reversal of apoptosis by the leukaemia-associated E2A-HLF chimaeric transcription factor.
- Rod differentiation factor NRL activates the expression of nuclear receptor NR2E3 to suppress the development of cone photoreceptors.
- Targeting of GFP to newborn rods by Nrl promoter and temporal expression profiling of flow-sorted photoreceptors.
- The bZIP transcription factor LCR-F1 is essential for mesoderm formation in mouse development.
- The polyphony of BACH2.
- The secretory pathway in control of endoplasmic reticulum homeostasis.
- The ubiquitous subunit of erythroid transcription factor NF-E2 is a small basic-leucine zipper protein related to the v-maf oncogene.
- The yeast Rab GTPase Ypt1 modulates unfolded protein response dynamics by regulating the stability of HAC1 RNA.
- Transformation of cone precursors to functional rod photoreceptors by bZIP transcription factor NRL.
- Unique evolution of the UPR pathway with a novel bZIP transcription factor, Hxl1, for controlling pathogenicity of Cryptococcus neoformans.
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Keywords of People
- Ciofani, Maria, Associate Professor of Immunology, Immunology
- Hogan, Brigid L. M., George Barth Geller Distinguished Professor of Immunology, Cell Biology