NF-E2 Transcription Factor

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  Subject Areas on Research

  • Complexity of CNC transcription factors as revealed by gene targeting of the Nrf3 locus. 
  • Ectopic expression of transcription factor NF-E2 alters the phenotype of erythroid and monoblastoid cells. 
  • Erythroid AP-1/NF-E2 elements vary in their response to NF-E2. 
  • Erythroid transcription factor NF-E2 coordinates hemoglobin synthesis. 
  • Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein. 
  • Human MafG is a functional partner for p45 NF-E2 in activating globin gene expression. 
  • Microcytic anemia in mk/mk mice is not corrected by retroviral-mediated gene transfer of wild-type p45 NF-E2. 
  • Mitogen-activated protein kinases enhance long-range activation by the beta-globin locus control region. 
  • Molecular characterization and localization of the human MAFG gene. 
  • Mouse microcytic anaemia caused by a defect in the gene encoding the globin enhancer-binding protein NF-E2. 
  • Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner. 
  • The NF-E2 transcription factor. 
  • The ubiquitous subunit of erythroid transcription factor NF-E2 is a small basic-leucine zipper protein related to the v-maf oncogene. 
  • cAMP-dependent protein kinase is necessary for increased NF-E2.DNA complex formation during erythroleukemia cell differentiation. 
  • p45 NF-E2 regulates expression of thromboxane synthase in megakaryocytes.