Large-Conductance Calcium-Activated Potassium Channels
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Subject Areas on Research
- A charged residue in S4 regulates coupling among the activation gate, voltage, and Ca2+ sensors in BK channels.
- An epilepsy/dyskinesia-associated mutation enhances BK channel activation by potentiating Ca2+ sensing.
- Calcium-sensitive potassium channelopathy in human epilepsy and paroxysmal movement disorder.
- Effects of multiple metal binding sites on calcium and magnesium-dependent activation of BK channels.
- Interaction between residues in the Mg2+-binding site regulates BK channel activation.
- Mg2+ mediates interaction between the voltage sensor and cytosolic domain to activate BK channels.
- Molecular mechanisms of BK channel activation.
- Presynaptic BK channels modulate ethanol-induced enhancement of GABAergic transmission in the rat central amygdala nucleus.
- Subunit-specific effect of the voltage sensor domain on Ca2+ sensitivity of BK channels.
- THG113.31, a specific PGF2alpha receptor antagonist, induces human myometrial relaxation and BKCa channel activation.