Oncogene Protein v-akt
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Subject Areas on Research
- A constitutively active form of neurokinin 1 receptor and neurokinin 1 receptor-mediated apoptosis in glioblastomas.
- Akt phosphorylates and activates HSF-1 independent of heat shock, leading to Slug overexpression and epithelial-mesenchymal transition (EMT) of HER2-overexpressing breast cancer cells.
- Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer.
- Cyr61 mediates hepatocyte growth factor-dependent tumor cell growth, migration, and Akt activation.
- Genetic alterations that inhibit in vivo pressure-overload hypertrophy prevent cardiac dysfunction despite increased wall stress.
- Genetic evidence of PTPN22 effects on chronic lymphocytic leukemia.
- Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma.
- Mitogen-activated protein kinase-interacting kinase regulates mTOR/AKT signaling and controls the serine/arginine-rich protein kinase-responsive type 1 internal ribosome entry site-mediated translation and viral oncolysis.
- Novel genetic loci underlying human intracranial volume identified through genome-wide association.
- Probiotic administration reduces mortality and improves intestinal epithelial homeostasis in experimental sepsis.
- Reduction in the requirement of oncogenic Ras signaling to activation of PI3K/AKT pathway during tumor maintenance.
- Reelin signals survival through Src-family kinases that inactivate BAD activity.
- Sonic hedgehog is an autocrine viability factor for myofibroblastic hepatic stellate cells.
- The clinical significance of activated p-AKT expression in peripheral T-cell lymphoma.
- Trefoil factor 3 stimulates human and rodent pancreatic islet beta-cell replication with retention of function.
- miR-19 is a key oncogenic component of mir-17-92.