Subject Areas on Research
- GFRα1 released by nerves enhances cancer cell perineural invasion through GDNF-RET signaling.
- Germline mutations in glial cell line-derived neurotrophic factor (GDNF) and RET in a Hirschsprung disease patient.
- Human GFRA1: cloning, mapping, genomic structure, and evaluation as a candidate gene for Hirschsprung disease susceptibility.
- Segregation at three loci explains familial and population risk in Hirschsprung disease.