Profilins

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  Subject Areas on Research

  • Actin dynamics: the arp2/3 complex branches out. 
  • Cdc42p regulation of the yeast formin Bni1p mediated by the effector Gic2p. 
  • Dynamic actin structures stabilized by profilin. 
  • Group-specific component (vitamin D binding protein) prevents the interaction between G-actin and profilin. 
  • Involvement of profilin in the actin-based motility of L. monocytogenes in cells and in cell-free extracts. 
  • Localization of a binding site for phosphatidylinositol 4,5-bisphosphate on human profilin. 
  • Mechanism of the interaction of human platelet profilin with actin. 
  • Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis. 
  • Pollen food syndrome: update on the allergens. 
  • Profilin, a weak CAP for actin and RAS. 
  • Profilin: at the crossroads of signal transduction and the actin cytoskeleton. 
  • Regulation of phospholipase C-gamma 1 by profilin and tyrosine phosphorylation. 
  • Roles of Hsl1p and Hsl7p in Swe1p degradation: beyond septin tethering. 
  • The actin-binding protein profilin binds to PIP2 and inhibits its hydrolysis by phospholipase C. 
  • The affinities of human platelet and Acanthamoeba profilin isoforms for polyphosphoinositides account for their relative abilities to inhibit phospholipase C. 
  • The control of actin nucleotide exchange by thymosin beta 4 and profilin. A potential regulatory mechanism for actin polymerization in cells.