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Subject Areas on Research
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"Model" behavior.
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"Silent" NMDA Synapses Enhance Motion Sensitivity in a Mature Retinal Circuit.
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'Chimeric' grafts assembled from multiple allodisparate donors enjoy enhanced transplant survival.
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'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR.
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(2S)-2-(3-(1-Carboxy-5-(4-211At-Astatobenzamido)Pentyl)Ureido)-Pentanedioic Acid for PSMA-Targeted α-Particle Radiopharmaceutical Therapy.
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(4-[18F]fluoro-3-iodobenzyl)guanidine, a potential MIBG analogue for positron emission tomography.
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(Aryloxy)aryl semicarbazones and related compounds: a novel class of anticonvulsant agents possessing high activity in the maximal electroshock screen.
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1 alpha,25 Dihydroxyvitamin D3 and mononuclear phagocytes: enhancement of mouse macrophage and human monocyte hydrogen peroxide production without alteration of tumor cytolysis.
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1,2,4-Trioxanes as potential antimalarial agents.
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1-(m-[211At]astatobenzyl)guanidine: synthesis via astato demetalation and preliminary in vitro and in vivo evaluation.
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1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced astrogliosis does not require activation of ornithine decarboxylase.
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125I-labeled anti-epidermal growth factor receptor-vIII single-chain Fv exhibits specific and high-level targeting of glioma xenografts.
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131I-labeled Anti-HER2 Camelid sdAb as a Theranostic Tool in Cancer Treatment.
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14-3-3 Proteins regulate mutant LRRK2 kinase activity and neurite shortening.
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17beta-Nitro-5alpha-androstan-3alpha-ol and its 3beta-methyl derivative: neurosteroid analogs with potent anticonvulsant and anxiolytic activities.
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17beta-estradiol differentially activates mitogen-activated protein-kinases and improves survival following reperfusion injury of reduced-size liver in mice.
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2'-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity.
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2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces peripheral blood abnormalities and plasma cell neoplasms resembling multiple myeloma in mice.
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2-O, 3-O-desulfated heparin inhibits neutrophil elastase-induced HMGB-1 secretion and airway inflammation.
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211At radiocolloid therapy: further observations and comparison with radiocolloids of 32P, 165Dy, and 90Y.
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211At- and 131I-labeled bisphosphonates with high in vivo stability and bone accumulation.
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25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner.
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27-Hydroxycholesterol Impairs Plasma Membrane Lipid Raft Signaling as Evidenced by Inhibition of IL6-JAK-STAT3 Signaling in Prostate Cancer Cells.
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27-Hydroxycholesterol links hypercholesterolemia and breast cancer pathophysiology.
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2B4 utilizes ITAM-containing receptor complexes to initiate intracellular signaling and cytolysis.
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3'UTR shortening of HAS2 promotes hyaluronan hyper-synthesis and bioenergetic dysfunction in pulmonary hypertension.
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3,4-Diaminopyridine (DAP) in the treatment of Lambert-Eaton myasthenic syndrome (LEMS).
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3-D Adaptive Sparsity Based Image Compression with Applications to Optical Coherence Tomography
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3-Halo-5,7-dimethylpyrazolo [1,5-a]pyrimidines, a nonbenzodiazepinoid class of antianxiety agents devoid of potentiation of central nervous system depressant effects of ethanol or barbiturates.
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3-[211At]astato-4-fluorobenzylguanidine: a potential therapeutic agent with prolonged retention by neuroblastoma cells.
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3D cardiac μtissues within a microfluidic device with real-time contractile stress readout.
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3D fiber tractography with susceptibility tensor imaging.
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3D model of frequency representation in the cochlear nucleus of the CBA/J mouse.
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3D printing of high-strength, porous, elastomeric structures to promote tissue integration of implants.
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3He MRI in mouse models of asthma.
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4-1BB Agonism Averts TIL Exhaustion and Licenses PD-1 Blockade in Glioblastoma and Other Intracranial Cancers.
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4-Aminopyridine attenuates muscle atrophy after sciatic nerve crush injury in mice.
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4-D micro-CT of the mouse heart.
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4.5 kb of the rat tyrosine hydroxylase 5' flanking sequence directs tissue specific expression during development and contains consensus sites for multiple transcription factors.
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440-kD ankyrinB: structure of the major developmentally regulated domain and selective localization in unmyelinated axons.
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4D MRI of polycystic kidneys from rapamycin-treated Glis3-deficient mice.
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4D micro-CT for cardiac and perfusion applications with view under sampling.
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4D micro-CT using fast prospective gating.
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5' UTR m(6)A Promotes Cap-Independent Translation.
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5' flanking sequences of the rat tyrosine hydroxylase gene target accurate tissue-specific, developmental, and transsynaptic expression in transgenic mice.
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5,6-EET is released upon neuronal activity and induces mechanical pain hypersensitivity via TRPA1 on central afferent terminals.
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5-HT2C Agonists Modulate Schizophrenia-Like Behaviors in Mice.
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5-Hydroxymethylcytosine (5hmC) and Ten-eleven translocation 1-3 (TET1-3) proteins in the dorsal root ganglia of mouse: Expression and dynamic regulation in neuropathic pain.
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5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors.
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58-kDa microspherule protein (MSP58) is novel Brahma-related gene 1 (BRG1)-associated protein that modulates p53/p21 senescence pathway.
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5α-Reductase inhibition coupled with short off cycles increases survival in the LNCaP xenograft prostate tumor model on intermittent androgen deprivation therapy.
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miR-146a
-Traf6
regulatory axis controls autoimmunity and myelopoiesis, but is dispensable for hematopoietic stem cell homeostasis and tumor suppression.
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A 1.3 kb promoter fragment confers spatial and temporal expression of utrophin A mRNA in mouse skeletal muscle fibers.
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A 10-gene progenitor cell signature predicts poor prognosis in lung adenocarcinoma.
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A 30-kDa alternative translation product of the CCAAT/enhancer binding protein alpha message: transcriptional activator lacking antimitotic activity.
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A 4-methyl-substituted meta-iodobenzylguanidine analogue with prolonged retention in human neuroblastoma cells.
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A 40-kilodalton protein binds specifically to an upstream sequence element essential for muscle-specific transcription of the human myoglobin promoter.
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A 57,000-mol-wt protein uniquely present in nonproliferating cells and senescent human fibroblasts.
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A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1.
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A Bayesian approach for joint modeling of cluster size and subunit-specific outcomes.
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A CD19-dependent signaling pathway regulates autoimmunity in Lyn-deficient mice.
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A CNS catecholaminergic cell line expresses voltage-gated currents.
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A CRISPR-Cas system enhances envelope integrity mediating antibiotic resistance and inflammasome evasion.
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A CRISPR/Cas9-based system for reprogramming cell lineage specification.
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A CaMK cascade activates CRE-mediated transcription in neurons of Caenorhabditis elegans.
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A Carcinogen-induced mouse model recapitulates the molecular alterations of human muscle invasive bladder cancer.
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A Circle RNA Regulatory Axis Promotes Lung Squamous Metastasis via CDR1-Mediated Regulation of Golgi Trafficking.
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A Combination of Ontogeny and CNS Environment Establishes Microglial Identity.
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A Commencement for Eye Commensals.
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A Common Neuroendocrine Substrate for Diverse General Anesthetics and Sleep.
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A Cyp2a polymorphism predicts susceptibility to NNK-induced lung tumorigenesis in mice.
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A DLL3-targeted antibody-drug conjugate eradicates high-grade pulmonary neuroendocrine tumor-initiating cells in vivo.
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A Deep Learning Approach to Antibiotic Discovery.
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A Diffusion MRI Tractography Connectome of the Mouse Brain and Comparison with Neuronal Tracer Data.
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A Distinct Function of Regulatory T Cells in Tissue Protection.
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A Fas-associated death domain protein/caspase-8-signaling axis promotes S-phase entry and maintains S6 kinase activity in T cells responding to IL-2.
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A Fluorescence-Guided Laser Ablation System for Removal of Residual Cancer in a Mouse Model of Soft Tissue Sarcoma.
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A Fluorescent Hsp90 Probe Demonstrates the Unique Association between Extracellular Hsp90 and Malignancy in Vivo.
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A Fluorometric Method of Measuring Carboxypeptidase Activities for Angiotensin II and Apelin-13.
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A GABAergic nigrotectal pathway for coordination of drinking behavior.
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A Genetically Defined Compartmentalized Striatal Direct Pathway for Negative Reinforcement.
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A Germline-Targeting Chimpanzee SIV Envelope Glycoprotein Elicits a New Class of V2-Apex Directed Cross-Neutralizing Antibodies.
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A Gαs DREADD mouse for selective modulation of cAMP production in striatopallidal neurons.
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A High-Throughput Organoid Microinjection Platform to Study Gastrointestinal Microbiota and Luminal Physiology.
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A Human Adult Stem Cell Signature Marks Aggressive Variants across Epithelial Cancers.
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A Human Pleiotropic Multiorgan Condition Caused by Deficient Wnt Secretion.
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A Knock-In Tristetraprolin (TTP) Zinc Finger Point Mutation in Mice: Comparison with Complete TTP Deficiency.
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A LCMS-based untargeted lipidomics analysis of cleft palate in mouse.
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A LGR5 reporter pig model closely resembles human intestine for improved study of stem cells in disease.
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A Liver-Specific Thyromimetic, VK2809, Decreases Hepatosteatosis in Glycogen Storage Disease Type Ia.
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A MAP kinase cascade composed of cell type specific and non-specific elements controls mating and differentiation of the fungal pathogen Cryptococcus neoformans.
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A Method to Target and Isolate Airway-innervating Sensory Neurons in Mice.
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A Modified Nucleoside 6-Thio-2'-Deoxyguanosine Exhibits Antitumor Activity in Gliomas.
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A Modified Transcranial Middle Cerebral Artery Occlusion Model to Study Stroke Outcomes in Aged Mice.
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A Molecular Switch Regulating Cell Fate Choice between Muscle Progenitor Cells and Brown Adipocytes.
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A Mouse Model of Orthopedic Surgery to Study Postoperative Cognitive Dysfunction and Tissue Regeneration.
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A Neural Circuit for Gut-Induced Reward.
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A Neurotrophic Mechanism Directs Sensory Nerve Transit in Cranial Bone.
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A Neutralizing IL-11 Antibody Improves Renal Function and Increases Lifespan in a Mouse Model of Alport Syndrome.
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A New, Second Generation Trithiol Bifunctional Chelate for 72,77As: Trithiol(b)-(Ser)2-RM2.
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A Non-Canonical Role for β-Secretase in the Retina.
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A Novel Murine Model of Marfan Syndrome Accelerates Aortopathy and Cardiomyopathy.
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A Novel Mycovirus Evokes Transcriptional Rewiring in the Fungus Malassezia and Stimulates Beta Interferon Production in Macrophages.
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A Novel Phosphoregulatory Switch Controls the Activity and Function of the Major Catalytic Subunit of Protein Kinase A in Aspergillus fumigatus.
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A PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophy.
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A PK2/Bv8/PROK2 antagonist suppresses tumorigenic processes by inhibiting angiogenesis in glioma and blocking myeloid cell infiltration in pancreatic cancer.
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A PRDM16-Driven Metabolic Signal from Adipocytes Regulates Precursor Cell Fate.
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A Peptide Uncoupling BDNF Receptor TrkB from Phospholipase Cγ1 Prevents Epilepsy Induced by Status Epilepticus.
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A Period2 Phosphoswitch Regulates and Temperature Compensates Circadian Period.
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A Phase I Trial of SYK Inhibition with Fostamatinib in the Prevention and Treatment of Chronic Graft-Versus-Host Disease.
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A Plasmonic Gold Nanostar Theranostic Probe for In Vivo Tumor Imaging and Photothermal Therapy.
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A Precision Medicine Drug Discovery Pipeline Identifies Combined CDK2 and 9 Inhibition as a Novel Therapeutic Strategy in Colorectal Cancer.
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A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface.
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A Protocol for the Comprehensive Flow Cytometric Analysis of Immune Cells in Normal and Inflamed Murine Non-Lymphoid Tissues.
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A Protocol for the Production of Integrase-deficient Lentiviral Vectors for CRISPR/Cas9-mediated Gene Knockout in Dividing Cells.
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A Protocol to Evaluate and Quantify Retinal Pigmented Epithelium Pathologies in Mouse Models of Age-Related Macular Degeneration.
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A RIPK3-caspase 8 complex mediates atypical pro-IL-1β processing.
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A Rare Mutation of β1-Adrenergic Receptor Affects Sleep/Wake Behaviors.
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A Ras1-Cdc24 signal transduction pathway mediates thermotolerance in the fungal pathogen Cryptococcus neoformans.
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A Rationally Designed Fully Human EGFRvIII:CD3-Targeted Bispecific Antibody Redirects Human T Cells to Treat Patient-derived Intracerebral Malignant Glioma.
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A Regenerative Cardiac Patch Formed by Spray Painting of Biomaterials onto the Heart.
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A Requirement of Protein Geranylgeranylation for Chemokine Receptor Signaling and Th17 Cell Function in an Animal Model of Multiple Sclerosis.
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A Roadmap to Heart Regeneration Through Conserved Mechanisms in Zebrafish and Mammals.
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A Role for Protease Activated Receptor Type 3 (PAR3) in Nociception Demonstrated Through Development of a Novel Peptide Agonist.
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A SMAP in the face for cancer.
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A Sch9 protein kinase homologue controlling virulence independently of the cAMP pathway in Cryptococcus neoformans.
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A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice.
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A Small Molecule Inhibitor of VE-PTP Activates Tie2 in Schlemm's Canal Increasing Outflow Facility and Reducing Intraocular Pressure.
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A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy.
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A Specialized Neural Circuit Gates Social Vocalizations in the Mouse.
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A T cell intrinsic role of Id3 in a mouse model for primary Sjogren's syndrome.
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A TAZ-AXL-ABL2 Feed-Forward Signaling Axis Promotes Lung Adenocarcinoma Brain Metastasis.
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A TRP Channel Senses Lysosome Neutralization by Pathogens to Trigger Their Expulsion.
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A TRPA1-dependent mechanism for the pungent sensation of weak acids.
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A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found In Vivo.
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A Virion-Based Combination Vaccine Protects against Influenza and SARS-CoV-2 Disease in Mice.
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A WAVE-1 and WRP signaling complex regulates spine density, synaptic plasticity, and memory.
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A Western diet induced NAFLD in LDLR(-/)(-) mice is associated with reduced hepatic glutathione synthesis.
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A Wor1-Like Transcription Factor Is Essential for Virulence of Cryptococcus neoformans.
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A Zika virus-specific IgM elicited in pregnancy exhibits ultrapotent neutralization.
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A balance between B cell receptor and inhibitory receptor signaling controls plasma cell differentiation by maintaining optimal Ets1 levels.
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A barrier-type insulator forms a boundary between active and inactive chromatin at the murine TCRβ locus.
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A beta cell subset with enhanced insulin secretion and glucose metabolism is reduced in type 2 diabetes.
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A beta-arrestin 2 signaling complex mediates lithium action on behavior.
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A beta-arrestin-biased agonist of the parathyroid hormone receptor (PTH1R) promotes bone formation independent of G protein activation.
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A bidirectional phage display vector for the selection and mass transfer of polyclonal antibody libraries.
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A binding site for Pax proteins regulates expression of the gene for the neural cell adhesion molecule in the embryonic spinal cord.
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A bioactive titanium foam scaffold for bone repair.
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A bipartite interaction between Hsp70 and CHIP regulates ubiquitination of chaperoned client proteins.
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A blood spot method for detecting fumonisin-induced changes in putative sphingolipid biomarkers in LM/Bc mice and humans.
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A brief history of tissue models for cardiac electrophysiology.
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A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice.
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A c-Fos- and E1A-interacting component of the tissue factor basal promoter complex mediates synergistic activation of transcription by transforming growth factor-beta1.
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A c-Myc and surface CD19 signaling amplification loop promotes B cell lymphoma development and progression in mice.
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A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type.
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A cancer rainbow mouse for visualizing the functional genomics of oncogenic clonal expansion.
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A candidate gene for congenital bilateral isolated ptosis identified by molecular analysis of a de novo balanced translocation.
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A candidate taste receptor gene near a sweet taste locus.
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A cardiac arrhythmia syndrome caused by loss of ankyrin-B function.
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A catalytic antioxidant (AEOL 10150) attenuates expression of inflammatory genes in stroke.
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A cell-intrinsic role for CaMKK2 in granulocyte lineage commitment and differentiation.
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A cell-intrinsic role for Mst1 in regulating thymocyte egress.
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A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation.
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A cell-specific nuclear receptor plays essential roles in adrenal and gonadal development.
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A cell-specific nuclear receptor regulates the steroid hydroxylases.
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A central role for Foxp3+ regulatory T cells in K-Ras-driven lung tumorigenesis.
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A cerebellar learning model of vestibulo-ocular reflex adaptation in wild-type and mutant mice.
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A chemical glycoproteomics platform reveals O-GlcNAcylation of mitochondrial voltage-dependent anion channel 2.
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A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes.
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A circuit for motor cortical modulation of auditory cortical activity.
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A circuit model for saccadic suppression in the superior colliculus.
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A class of viral inducer of degradation of the necroptosis adaptor RIPK3 regulates virus-induced inflammation.
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A combination of independent transcriptional regulators shapes bacterial virulence gene expression during infection.
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A common ankyrin-G-based mechanism retains KCNQ and NaV channels at electrically active domains of the axon.
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A common single nucleotide polymorphism A118G of the μ opioid receptor alters its N-glycosylation and protein stability.
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A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome.
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A comparative analysis of EGFR-targeting antibodies for gold nanoparticle CT imaging of lung cancer.
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A comparative study of the distributions of renin and angiotensinogen messenger ribonucleic acids in rat and mouse tissues.
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A comparison of antiangiogenic therapies for the prevention of liver metastases.
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A comparison of least squares and conditional maximum likelihood estimators under volume endpoint censoring in tumor growth experiments.
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A comparison of murine T-cell-depleted adult bone marrow and full-term fetal blood cells in hematopoietic engraftment and immune reconstitution.
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A comparison of non-toxin vaccine adjuvants for their ability to enhance the immunogenicity of nasally-administered anthrax recombinant protective antigen.
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A comparison of oral and rectal absorption of L-dopa esters in rats and mice.
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A comparison of radial keyhole strategies for high spatial and temporal resolution 4D contrast-enhanced MRI in small animal tumor models.
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A comparison of strain-related susceptibility in two murine recovery models of global cerebral ischemia.
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A comparison of the genes coding for canonical TRP channels and their M, V and P relatives.
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A complex of distal appendage-associated kinases linked to human disease regulates ciliary trafficking and stability.
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A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis.
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A comprehensive method for optical-emission computed tomography.
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A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity.
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A computer model of engineered cardiac monolayers.
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A conserved docking motif for CK1 binding controls the nuclear localization of NFAT1.
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A conserved retromer-independent function for RAB-6.2 in C. elegans epidermis integrity.
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A conserved transcriptional enhancer regulates RAG gene expression in developing B cells.
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A controlled-release strategy for the generation of cross-linked hydrogel microstructures.
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A cord blood monocyte-derived cell therapy product accelerates brain remyelination.
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A cortical circuit for gain control by behavioral state.
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A cortical filter that learns to suppress the acoustic consequences of movement.
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A cortico-hippocampal learning rule shapes inhibitory microcircuit activity to enhance hippocampal information flow.
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A craniofacial-specific monosynaptic circuit enables heightened affective pain.
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A critical precursor frequency of donor-reactive CD4+ T cell help is required for CD8+ T cell-mediated CD28/CD154-independent rejection.
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A critical role for ChREBP-mediated FGF21 secretion in hepatic fructose metabolism.
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A critical role for chloride channel-3 (CIC-3) in smooth muscle cell activation and neointima formation.
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A critical role for the autophagy gene Atg5 in T cell survival and proliferation.
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A critical role of eEF-2K in mediating autophagy in response to multiple cellular stresses.
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A cross-species approach using an in vivo evaluation platform in mice demonstrates that sequence variation in human RABEP2 modulates ischemic stroke outcomes.
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A crucial role of L-selectin in C protein-induced experimental polymyositis in mice.
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A cut above the other caspases.
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A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation.
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A cytogenetic comparison of the responses of mouse and human peripheral blood lymphocytes to 60Co gamma radiation.
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A cytokine cocktail directly modulates the phenotype of DC-enriched anti-tumor T cells to convey potent anti-tumor activities in a murine model.
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A de novo deafwaddler mutation of Pmca2 arising in ES cells and hitchhiking with a targeted modification of the Pparg gene.
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A defect in the humoral immune response to protein antigens and haptens in immunoglobulin mu heavy-chain transgenic mice.
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A deficit in astroglial organization causes the impaired reactive sprouting in human apolipoprotein E4 targeted replacement mice.
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A depot-forming glucagon-like peptide-1 fusion protein reduces blood glucose for five days with a single injection.
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A designed glycoprotein analogue of Gc-MAF exhibits native-like phagocytic activity.
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A detrimental role of RelB in mature oligodendrocytes during experimental acute encephalomyelitis.
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A developmental switch from TCR delta enhancer to TCR alpha enhancer function during thymocyte maturation.
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A differential role for endocytosis in receptor-mediated activation of Nox1.
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A direct HDAC4-MAP kinase crosstalk activates muscle atrophy program.
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A direct link between carbohydrate utilization and virulence in the major human pathogen group A Streptococcus.
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A discrete chromatin loop in the mouse Tcra-Tcrd locus shapes the TCRδ and TCRα repertoires.
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A disinhibitory circuit mediates motor integration in the somatosensory cortex.
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A diverse population of Cryptococcus gattii molecular type VGIII in southern Californian HIV/AIDS patients.
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A double hit to kill tumor and endothelial cells by TRAIL and antiangiogenic 3TSR.
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A dual-emissive-materials design concept enables tumour hypoxia imaging.
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A family of candidate taste receptors in human and mouse.
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A family of hierarchically self-assembling linear-dendritic hybrid polymers for highly efficient targeted gene delivery.
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A feasibility study using radiochromic films for fast neutron 2D passive dosimetry.
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A fixative for use in muscle histochemistry.
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A flucytosine-responsive Mbp1/Swi4-like protein, Mbs1, plays pleiotropic roles in antifungal drug resistance, stress response, and virulence of Cryptococcus neoformans.
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A fluorescent assay for agonist-activated phospholipase D in mammalian cell extracts.
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A fluorogenic C. neoformans reporter strain with a robust expression of m-cherry expressed from a safe haven site in the genome.
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A functional analysis of the spacer of V(D)J recombination signal sequences.
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A functional genomics predictive network model identifies regulators of inflammatory bowel disease.
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A functional mouse ornithine decarboxylase gene (Odc) maps to chromosome 12: further evidence of homoeology between mouse chromosome 12 and the short arm of human chromosome 2.
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A functional role for circulating mouse L-selectin in regulating leukocyte/endothelial cell interactions in vivo.
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A functional variant in HOXA11-AS, a novel long non-coding RNA, inhibits the oncogenic phenotype of epithelial ovarian cancer.
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A futile metabolic cycle activated in adipocytes by antidiabetic agents.
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A gammaGT-AT1A receptor transgene protects renal cortical structure in AT1 receptor-deficient mice.
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A gene atlas of the mouse and human protein-encoding transcriptomes.
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A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes.
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A general approach for two-stage analysis of multilevel clustered non-Gaussian data.
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A genetic approach for studying the physiology of the type 1A (AT1A) angiotensin receptor.
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A genetically defined disease model reveals that urothelial cells can initiate divergent bladder cancer phenotypes.
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A genetically defined normal human somatic cell system to study ras oncogenesis in vivo and in vitro.
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A genetically engineered thermally responsive sustained release curcumin depot to treat neuroinflammation.
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A genetically modified allogeneic cellular vaccine generates MHC class I-restricted cytotoxic responses against tumor-associated antigens and protects against CNS tumors in vivo.
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A genetically tractable model of human glioma formation.
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A genome end-game: understanding gene function in the nervous system.
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A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene.
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A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25.
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A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes.
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A genomic survey of positive selection in Burkholderia pseudomallei provides insights into the evolution of accidental virulence.
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A glutaminase isoform switch drives therapeutic resistance and disease progression of prostate cancer.
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A glycoengineered anti-CD19 antibody with potent antibody-dependent cellular cytotoxicity activity in vitro and lymphoma growth inhibition in vivo.
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A grafted ovarian fragment rescues host fertility after chemotherapy.
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A guide to analysis of mouse energy metabolism.
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A gut-brain neural circuit for nutrient sensory transduction.
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A hapten generated from an oxidation fragment of docosahexaenoic acid is sufficient to initiate age-related macular degeneration.
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A hierarchy of ankyrin-spectrin complexes clusters sodium channels at nodes of Ranvier.
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A high affinity, antidote-controllable prothrombin and thrombin-binding RNA aptamer inhibits thrombin generation and thrombin activity.
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A high expression level of insulin-like growth factor I receptor is associated with increased expression of transcription factor Sp1 and regional lymph node metastasis of human gastric cancer.
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A high throughput screen identifies Nefopam as targeting cell proliferation in β-catenin driven neoplastic and reactive fibroproliferative disorders.
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A high-density integrated genetic linkage and radiation hybrid map of the laboratory rat.
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A high-performance liquid chromatography method for the quantification of cysmethynil, an inhibitor of isoprenylcysteine carboxylmethyl transferase, in mouse plasma.
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A high-precision contrast injector for small animal x-ray digital subtraction angiography.
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A high-resolution anatomical ontology of the developing murine genitourinary tract.
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A high-temperature superconducting Helmholtz probe for microscopy at 9.4 T.
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A high-throughput in vitro drug screen in a genetically engineered mouse model of diffuse intrinsic pontine glioma identifies BMS-754807 as a promising therapeutic agent.
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A highly polarized TH2 bladder response to infection promotes epithelial repair at the expense of preventing new infections.
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A highly selective Hsp90 affinity chromatography resin with a cleavable linker.
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A human CD46 transgenic pig model system for the study of discordant xenotransplantation.
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A human erythropoietin receptor gene mutant causing familial erythrocytosis is associated with deregulation of the rates of Jak2 and Stat5 inactivation.
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A human immunoglobulin gene reduces the incidence of lymphomas in c-Myc-bearing transgenic mice.
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A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.
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A humanized mouse model to study mast cells mediated cutaneous adverse drug reactions.
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A hypothetic mechanism of diethylstilbestrol(DES)-induced anomalies in exposed progeny.
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A kinome RNAi screen identified AMPK as promoting poxvirus entry through the control of actin dynamics.
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A large U3 deletion causes increased in vivo expression from a nonintegrating lentiviral vector.
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A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen.
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A liposomal nanoscale contrast agent for preclinical CT in mice.
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A local hyperthermia treatment which enhances antibody uptake in a glioma xenograft model does not affect tumour interstitial fluid pressure.
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A locus mapping to mouse chromosome 7 determines infarct volume in a mouse model of ischemic stroke.
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A long-acting formulation of rifabutin is effective for prevention and treatment of Mycobacterium tuberculosis.
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A lymphotoxin-IFN-beta axis essential for lymphocyte survival revealed during cytomegalovirus infection.
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A lytic polysaccharide monooxygenase-like protein functions in fungal copper import and meningitis.
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A macrophage subpopulation recruited by CC chemokine ligand-2 clears apoptotic cells in noninfectious lung injury.
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A macrophage-endothelial immunoregulatory axis ameliorates septic acute kidney injury.
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A macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleus.
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A major role for the EP4 receptor in regulation of renin.
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A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia.
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A manganese porphyrin superoxide dismutase mimetic enhances tumor radioresponsiveness.
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A mast cell-thermoregulatory neuron circuit axis regulates hypothermia in anaphylaxis.
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A mastoparan-derived peptide has broad-spectrum antiviral activity against enveloped viruses.
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A mathematical model of tryptophan metabolism via the kynurenine pathway provides insights into the effects of vitamin B-6 deficiency, tryptophan loading, and induction of tryptophan 2,3-dioxygenase on tryptophan metabolites.
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A mechanism for expansion of regulatory T-cell repertoire and its role in self-tolerance.
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A mechanism for gene-environment interaction in the etiology of congenital scoliosis.
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A mechanism-based antioxidant approach for the reduction of skin carcinogenesis.
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A mechanism-based complementary screening approach for the amelioration and reversal of neurobehavioral teratogenicity.
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A member of a family of sulfate-activating enzymes causes murine brachymorphism.
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A membrane-associated progesterone-binding protein, 25-Dx, is regulated by progesterone in brain regions involved in female reproductive behaviors.
-
A metabolic enzyme for S-nitrosothiol conserved from bacteria to humans.
-
A metalloporphyrin antioxidant alters cytokine responses after irradiation in a prostate tumor model.
-
A metalloporphyrin-based superoxide dismutase mimic inhibits adoptive transfer of autoimmune diabetes by a diabetogenic T-cell clone.
-
A method for linking VL and VH region genes that allows bulk transfer between vectors for use in generating polyclonal IgG libraries.
-
A method for the continuous calculation of the age of labeled red blood cells.
-
A method for the radiohalogenation of proteins resulting in decreased thyroid uptake of radioiodine.
-
A methodology for utilization of predictive genomic signatures in FFPE samples.
-
A methylthioadenosine phosphorylase (MTAP) fusion transcript identifies a new gene on chromosome 9p21 that is frequently deleted in cancer.
-
A micro-CT analysis of murine lung recruitment in bleomycin-induced lung injury.
-
A micro-computed tomography-based method for the measurement of pulmonary compliance in healthy and bleomycin-exposed mice.
-
A microarray analysis of the XX Wnt4 mutant gonad targeted at the identification of genes involved in testis vascular differentiation.
-
A microarray analysis of the XX Wnt4 mutant gonad targeted at the identification of genes involved in testis vascular differentiation.
-
A microfluidic system for investigation of extravascular transport and cellular uptake of drugs in tumors.
-
A mitotic recombination system for mouse chromosome 17.
-
A model for RAS mutation patterns in cancers: finding the sweet spot.
-
A model for human medulloblastoma. Growth, morphology, and chromosomal analysis in vitro and in athymic mice.
-
A model for optimizing adenoviral delivery in human cancer gene therapy trials.
-
A model of muscle atrophy using cast immobilization in mice.
-
A modern Cosmas and Damian: Sir Roy Calne and Thomas Starzl receive the 2012 Lasker~Debakey Clinical Medical Research Award.
-
A modified vaccinia Ankara vector-based vaccine protects macaques from SARS-CoV-2 infection, immune pathology, and dysfunction in the lungs.
-
A monoclonal antibody IMab-1 specifically recognizes IDH1R132H, the most common glioma-derived mutation.
-
A monoclonal antibody reactive with a second epitope of the 67,000-dalton human T cell antigen.
-
A monoclonal antibody specific for the amino terminal sequence of human prorenin identifies a common epitope on renal and amniotic fluid inactive renins.
-
A monoclonal antibody that targets a NaV1.7 channel voltage sensor for pain and itch relief.
-
A morphological analysis endocrine tumour genesis in pancreas and anterior pituitary of AVP/SV40 transgenic mice.
-
A mosaic analysis system with Cre or Tomato expression in the mouse.
-
A mouse bleeding model to study oral anticoagulants.
-
A mouse homoeo box gene is expressed during embryogenesis and in adult kidney.
-
A mouse homologue of FAST-1 transduces TGF beta superfamily signals and is expressed during early embryogenesis.
-
A mouse macrophage lipidome.
-
A mouse model engineered to conditionally express the progesterone receptor-B isoform.
-
A mouse model for heparin-induced thrombocytopenia.
-
A mouse model for hereditary hemorrhagic telangiectasia (HHT) type 2.
-
A mouse model for human osteogenesis imperfecta type VI.
-
A mouse model of adult-onset anaemia due to erythropoietin deficiency.
-
A mouse model of congenital heart disease: cardiac arrhythmias and atrial septal defect caused by haploinsufficiency of the cardiac transcription factor Csx/Nkx2.5.
-
A mouse model of familial porphyria cutanea tarda.
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A mouse model of heart failure with preserved ejection fraction due to chronic infusion of a low subpressor dose of angiotensin II.
-
A mouse model of higher visual cortical function.
-
A mouse model of juvenile hemochromatosis.
-
A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer.
-
A multigene family encoding a diverse array of putative pheromone receptors in mammals.
-
A multimodal cell census and atlas of the mammalian primary motor cortex.
-
A multimodal micro-optrode combining field and single unit recording, multispectral detection and photolabeling capabilities.
-
A murine Ig light chain transgene reveals IGKV3 gene contributions to anti-collagen types IV and II specificities.
-
A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response.
-
A murine model for short-chain acyl-CoA dehydrogenase deficiency.
-
A murine model of congenital toxoplasmic retinochoroiditis.
-
A murine model of hyperdopaminergic state displays altered respiratory control.
-
A murine model of increased coronary sinus pressure induces myocardial edema with cardiac lymphatic dilation and fibrosis.
-
A murine monoclonal antibody directed against the carboxyl-terminal domain of GRP78 suppresses melanoma growth in mice.
-
A mutant PTH/PTHrP type I receptor in enchondromatosis.
-
A mutation in Sec15l1 causes anemia in hemoglobin deficit (hbd) mice.
-
A mutation in a mitochondrial transmembrane protein is responsible for the pleiotropic hematological and skeletal phenotype of flexed-tail (f/f) mice.
-
A mutation in the glycine binding pocket of the N-methyl-D-aspartate receptor NR1 subunit alters agonist efficacy.
-
A near-infrared genetically encoded calcium indicator for in vivo imaging.
-
A network of genetic events sufficient to convert normal human cells to a tumorigenic state.
-
A network of substrates of the E3 ubiquitin ligases MDM2 and HUWE1 control apoptosis independently of p53.
-
A neural circuit for spatial summation in visual cortex.
-
A neural network-based method for spectral distortion correction in photon counting x-ray CT.
-
A neuronal model of Alzheimer's disease: an insight into the mechanisms of oxidative stress-mediated mitochondrial injury.
-
A neutralizing epitope of the superantigen SEA has agonist activity on T cells.
-
A new Cre driver mouse line, Tcf21/Pod1-Cre, targets metanephric mesenchyme.
-
A new EV71 VP3 epitope in norovirus P particle vector displays neutralizing activity and protection in vivo in mice.
-
A new Kupffer cell receptor mediating plasma clearance of carcinoembryonic antigen by the rat.
-
A new SOD mimic, Mn(III) ortho N-butoxyethylpyridylporphyrin, combines superb potency and lipophilicity with low toxicity.
-
A new activating role for CO in cardiac mitochondrial biogenesis.
-
A new method for the cytological analysis of autoantibody specificities using whole-mount, surface-spread meiotic nuclei.
-
A new model of Epstein-Barr virus infection reveals an important role for early lytic viral protein expression in the development of lymphomas.
-
A new procedure for the synthesis of polyethylene glycol-protein adducts; effects on function, receptor recognition, and clearance of superoxide dismutase, lactoferrin, and alpha 2-macroglobulin.
-
A new role for ATM: regulating mitochondrial function and mitophagy.
-
A new strategy for studying protein kinase B and its three isoforms. Role of protein kinase B in phosphorylating glycogen synthase kinase-3, tuberin, WNK1, and ATP citrate lyase.
-
A new synthetic protectin D1 analog 3-oxa-PD1n-3 DPA reduces neuropathic pain and chronic itch in mice.
-
A new temperature-sensitive liposome for use with mild hyperthermia: characterization and testing in a human tumor xenograft model.
-
A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer.
-
A no-laminectomy spinal cord compression injury model in mice.
-
A non-neutralizing glycoprotein B monoclonal antibody protects against herpes simplex virus disease in mice.
-
A non-oncogenic HPV 16 E6/E7 vaccine enhances treatment of HPV expressing tumors.
-
A nonantigenic covalent streptokinase-polyethylene glycol complex with plasminogen activator function.
-
A nonpolio enterovirus with respiratory tropism causes poliomyelitis in intercellular adhesion molecule 1 transgenic mice.
-
A novel Bcr-Abl-mTOR-eIF4A axis regulates IRES-mediated translation of LEF-1.
-
A novel Cbx1, PurB, and Sp3 complex mediates long-term silencing of tissue- and lineage-specific genes.
-
A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism.
-
A novel EGFR isoform confers increased invasiveness to cancer cells.
-
A novel angiopoietin-derived peptide displays anti-angiogenic activity and inhibits tumour-induced and retinal neovascularization.
-
A novel antisense inhibitor of MMP-9 attenuates angiogenesis, human prostate cancer cell invasion and tumorigenicity.
-
A novel apoE-derived therapeutic reduces vasospasm and improves outcome in a murine model of subarachnoid hemorrhage.
-
A novel approach to maintain gut mucosal integrity using an oral enzyme supplement.
-
A novel basal promoter element is required for expression of the rat tyrosine hydroxylase gene.
-
A novel bioreactor for combined magnetic resonance spectroscopy and optical imaging of metabolism in 3D cell cultures.
-
A novel catecholamine-activated adenosine cyclic 3',5'-phosphate independent pathway for beta-adrenergic receptor phosphorylation in wild-type and mutant S49 lymphoma cells: mechanism of homologous desensitization of adenylate cyclase.
-
A novel conditionally replicating "armed" adenovirus selectively targeting gastrointestinal tumors with aberrant wnt signaling.
-
A novel flow-perfusion bioreactor supports 3D dynamic cell culture.
-
A novel genetic locus modulates infarct volume independently of the extent of collateral circulation.
-
A novel human endometrial epithelial cell line for modeling gynecological diseases and for drug screening.
-
A novel humanized mouse lacking murine P450 oxidoreductase for studying human drug metabolism.
-
A novel immune competent murine hypertrophic scar contracture model: a tool to elucidate disease mechanism and develop new therapies.
-
A novel immunocompetent murine tumor model for the evaluation of RCAd-enhanced RDAd transduction efficacy.
-
A novel immunomodulatory protein from Poria cocos induces Toll-like receptor 4-dependent activation within mouse peritoneal macrophages.
-
A novel in vitro assay of tumor-initiating cells in xenograft prostate tumors.
-
A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T cells.
-
A novel intracellular protein delivery platform based on single-protein nanocapsules
-
A novel mechanism for Bcr-Abl action: Bcr-Abl-mediated induction of the eIF4F translation initiation complex and mRNA translation.
-
A novel mechanism for regulating transforming growth factor beta (TGF-beta) signaling. Functional modulation of type III TGF-beta receptor expression through interaction with the PDZ domain protein, GIPC.
-
A novel mechanism of skin tumor promotion involving interferon-gamma (IFNγ)/signal transducer and activator of transcription-1 (Stat1) signaling.
-
A novel method for in vitro culture and expansion of nonhuman primate B cells.
-
A novel method for viral gene delivery in solid tumors.
-
A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development.
-
A novel model system for studying the double-edged roles of nitric oxide production in pancreatic cancer growth and metastasis.
-
A novel modifier gene for plasma von Willebrand factor level maps to distal mouse chromosome 11.
-
A novel monoclonal antibody to secreted frizzled-related protein 2 inhibits tumor growth.
-
A novel mouse model of cerebral cavernous malformations based on the two-hit mutation hypothesis recapitulates the human disease.
-
A novel mouse model of podocyte depletion.
-
A novel mouse model of red blood cell storage and posttransfusion in vivo survival.
-
A novel murine model of human renal cell carcinoma spinal metastasis.
-
A novel murine model of inflammatory bowel disease and inflammation-associated colon cancer with ulcerative colitis-like features.
-
A novel murine oncornavirus with dual eco- and xenotropic properties.
-
A novel murine protein with no effect on iron homoeostasis is homologous with transferrin and is the putative inhibitor of carbonic anhydrase.
-
A novel mutation in the erythropoietin receptor gene is associated with familial erythrocytosis.
-
A novel neoplastic primary tumor-derived human prostate epithelial cell line.
-
A novel neurotoxoid vaccine prevents mucosal botulism.
-
A novel receptor function for the heat shock protein Grp78: silencing of Grp78 gene expression attenuates alpha2M*-induced signalling.
-
A novel redox regulator, MnTnBuOE-2-PyP5+, enhances normal hematopoietic stem/progenitor cell function.
-
A novel rodent mammary window of orthotopic breast cancer for intravital microscopy.
-
A novel role for HEB downstream or parallel to the pre-TCR signaling pathway during alpha beta thymopoiesis.
-
A novel role for activation-induced cytidine deaminase: central B-cell tolerance.
-
A novel role for the centrosomal protein, pericentrin, in regulation of insulin secretory vesicle docking in mouse pancreatic beta-cells.
-
A novel role for type 1 angiotensin receptors on T lymphocytes to limit target organ damage in hypertension.
-
A novel species-specific RNA related to alternatively spliced amyloid precursor protein mRNAs.
-
A novel therapeutic derived from apolipoprotein E reduces brain inflammation and improves outcome after closed head injury.
-
A novel toll-like receptor 9 agonist cooperates with trastuzumab in trastuzumab-resistant breast tumors through multiple mechanisms of action.
-
A novel ubiquitin fusion system bypasses the mitochondria and generates biologically active Smac/DIABLO.
-
A novel, clinically relevant animal model of metastatic pancreatic adenocarcinoma biology and therapy.
-
A one-photon endoscope for simultaneous patterned optogenetic stimulation and calcium imaging in freely behaving mice.
-
A p-[18F]fluoroethoxyphenyl bicyclic nucleoside analogue as a potential positron emission tomography imaging agent for varicella-zoster virus thymidine kinase gene expression.
-
A pH-gated conformational switch regulates the phosphatase activity of bifunctional HisKA-family histidine kinases.
-
A paclitaxel-loaded recombinant polypeptide nanoparticle outperforms Abraxane in multiple murine cancer models.
-
A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency.
-
A peptide inhibitor derived from p55PIK phosphatidylinositol 3-kinase regulatory subunit: a novel cancer therapy.
-
A pharmacoproteomic approach implicates eukaryotic elongation factor 2 kinase in ER stress-induced cell death.
-
A phase I trial of hyperthermia-induced interleukin-12 gene therapy in spontaneously arising feline soft tissue sarcomas.
-
A phase I-II study evaluating the murine anti-IL-2 receptor antibody 2A3 for treatment of acute graft-versus-host disease.
-
A physical map of the mouse genome.
-
A piggyBac insertion disrupts Foxl2 expression that mimics BPES syndrome in mice.
-
A pilot study: 131I-antitenascin monoclonal antibody 81c6 to deliver a 44-Gy resection cavity boost.
-
A point mutation (D79N) of the alpha2A adrenergic receptor abolishes the antiepileptogenic action of endogenous norepinephrine.
-
A portable ventilator with integrated physiologic monitoring for hyperpolarized 129Xe MRI in rodents.
-
A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair.
-
A precisely regulated gene expression cassette potently modulates metastasis and survival in multiple solid cancers.
-
A preliminary gene map for the Van der Woude syndrome critical region derived from 900 kb of genomic sequence at 1q32-q41.
-
A preliminary investigation of the parallelogram concept in genetic monitoring and risk estimation.
-
A preliminary study on efficacy of rupatadine for the treatment of acute dengue infection.
-
A primary role for K+ and Na+ efflux in the activation of apoptosis.
-
A prior feature SVM-MRF based method for mouse brain segmentation.
-
A probabilistic approach to demixing odors.
-
A procedure for the preferential radioiodination of small amounts of protein in the presence of excess lipids.
-
A proposal for a coordinated effort for the determination of brainwide neuroanatomical connectivity in model organisms at a mesoscopic scale.
-
A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling.
-
A proteomic approach for dissecting H-Ras signaling networks in NIH/3T3 mouse embryonic fibroblast cells.
-
A proteomic approach for unraveling the oncogenic H-Ras protein networks in NIH/3T3 mouse embryonic fibroblast cells.
-
A proteomics approach to the identification of mammalian mitochondrial small subunit ribosomal proteins.
-
A protocol for heterologous expression and functional assay for mouse pheromone receptors.
-
A quantitative map of the liver mitochondrial phosphoproteome reveals posttranslational control of ketogenesis.
-
A quantitative microscopic approach to predict local recurrence based on in vivo intraoperative imaging of sarcoma tumor margins.
-
A quantitative trait locus (LSq-1) on mouse chromosome 7 is linked to the absence of tissue loss after surgical hindlimb ischemia.
-
A rapid cytoplasmic mechanism for PI3 kinase regulation by the nuclear thyroid hormone receptor, TRβ, and genetic evidence for its role in the maturation of mouse hippocampal synapses in vivo.
-
A rapidly dividing human medulloblastoma cell line (D283 MED) expresses all three neurofilament subunits.
-
A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents.
-
A registration based approach for 4D cardiac micro-CT using combined prospective and retrospective gating.
-
A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses.
-
A requirement for NF-kappaB activation in Bcr-Abl-mediated transformation.
-
A resource of Cre driver lines for genetic targeting of GABAergic neurons in cerebral cortex.
-
A reversible aptamer improves outcome and safety in murine models of stroke and hemorrhage.
-
A revised airway epithelial hierarchy includes CFTR-expressing ionocytes.
-
A robust protocol for regional evaluation of methacholine challenge in mouse models of allergic asthma using hyperpolarized 3He MRI.
-
A rodent model of spontaneous stereotypy: initial characterization of developmental, environmental, and neurobiological factors.
-
A role for AQP5 in activation of TRPV4 by hypotonicity: concerted involvement of AQP5 and TRPV4 in regulation of cell volume recovery.
-
A role for CD21/CD35 and CD19 in responses to acute septic peritonitis: a potential mechanism for mast cell activation.
-
A role for E2F activities in determining the fate of Myc-induced lymphomagenesis.
-
A role for MAPK in feedback inhibition of Tcrb recombination.
-
A role for Pin1 in mammalian germ cell development and spermatogenesis.
-
A role for Sfrp2 in cardiomyogenesis in vivo.
-
A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth program.
-
A role for TREK1 in generating the slow afterhyperpolarization in developing starburst amacrine cells.
-
A role for a lithium-inhibited Golgi nucleotidase in skeletal development and sulfation.
-
A role for angiotensin II type 1 receptors on bone marrow-derived cells in the pathogenesis of angiotensin II-dependent hypertension.
-
A role for c-FLIP(L) in the regulation of apoptosis, autophagy, and necroptosis in T lymphocytes.
-
A role for cFLIP in B cell proliferation and stress MAPK regulation.
-
A role for cohesin in T-cell-receptor rearrangement and thymocyte differentiation.
-
A role for fractalkine and its receptor (CX3CR1) in cardiac allograft rejection.
-
A role for histone acetylation in the developmental regulation of VDJ recombination.
-
A role for immunogenic DNA in the pathogenesis of systemic lupus erythematosus.
-
A role for peroxisome proliferator-activated receptor γ coactivator-1 in the control of mitochondrial dynamics during postnatal cardiac growth.
-
A role for the CD38
rs3796863 polymorphism in alcohol and monetary reward: evidence from CD38 knockout mice and alcohol self-administration, [11C]-raclopride binding, and functional MRI in humans.
-
A role for the chemokine receptor CCR6 in mammalian sperm motility and chemotaxis.
-
A role for the copper transporter Ctr1 in the synergistic interaction between hyperthermia and cisplatin treatment.
-
A role for the cytoplasmic tail of the beta chain of CD8 in thymic selection.
-
A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection.
-
A role for the thromboxane receptor in L-NAME hypertension.
-
A role for transient receptor potential vanilloid 4 in tonicity-induced neurogenic inflammation.
-
A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses.
-
A role for ΔFosB in calorie restriction-induced metabolic changes.
-
A role of matrix metalloproteinase-8 in atherosclerosis.
-
A route to brightly fluorescent carbon nanotubes for near-infrared imaging in mice.
-
A scanning electron microscope study of the extraembryonic endoderm of the 8th-day mouse embryo.
-
A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress.
-
A self-adjuvanting supramolecular vaccine carrying a folded protein antigen.
-
A self-assembling peptide acting as an immune adjuvant.
-
A seminal finding for prostate cancer?
-
A sensitized genetic system for the analysis of murine B lymphocyte signal transduction pathways dependent on Bruton's tyrosine kinase.
-
A sensitized mutagenesis screen identifies Gli3 as a modifier of Sox10 neurocristopathy.
-
A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma.
-
A serially transplantable human giant cell glioblastoma that maintains a near-haploid stem line.
-
A shared vision.
-
A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells.
-
A simple and enzyme-free method for processing infiltrating lymphocytes from small mouse tumors for ELISpot analysis.
-
A simple, efficient tool for assessment of mice after unilateral cortex injury.
-
A simplified synthesis of the hypoxia imaging agent 2-(2-Nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-[(18)F]pentafluoropropyl)-acetamide ([18F]EF5).
-
A single amino acid change in the cytoplasmic domain of the simian immunodeficiency virus transmembrane molecule increases envelope glycoprotein expression on infected cells.
-
A single genetic locus determines the efficacy of serum therapy against murine adenocarcinoma 755a.
-
A single valine residue plays an essential role in peripherin/rds targeting to photoreceptor outer segments.
-
A small molecule targeting ALOX12-ACC1 ameliorates nonalcoholic steatohepatitis in mice and macaques.
-
A small regulatory element from chromosome 19 enhances liver-specific gene expression.
-
A small-molecule antagonist of the hedgehog signaling pathway.
-
A small-molecule inhibitor of isoprenylcysteine carboxyl methyltransferase with antitumor activity in cancer cells.
-
A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain.
-
A spontaneous deletion within the desmoglein 3 extracellular domain of mice results in hypomorphic protein expression, immunodeficiency, and a wasting disease phenotype.
-
A spontaneous, recurrent mutation in divalent metal transporter-1 exposes a calcium entry pathway.
-
A statin-regulated microRNA represses human c-Myc expression and function.
-
A stimulus-specific role for CREB-binding protein (CBP) in T cell receptor-activated tumor necrosis factor alpha gene expression.
-
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1.
-
A striatal interneuron circuit for continuous target pursuit.
-
A study of cataract in murine congenital toxoplasmosis.
-
A study of dendritic and endothelial cell interactions in colon cancer in a cell line and small mammal model.
-
A subgroup of murine monoclonal anti-deoxyribonucleic acid antibodies traverse the cytoplasm and enter the nucleus in a time-and temperature- dependent manner.
-
A sublingual nanofiber vaccine to prevent urinary tract infections.
-
A symmetrical Waxholm canonical mouse brain for NeuroMaps.
-
A synaptic and circuit basis for corollary discharge in the auditory cortex.
-
A synthetic matrix with independently tunable biochemistry and mechanical properties to study epithelial morphogenesis and EMT in a lung adenocarcinoma model.
-
A synthetic random basic copolymer with promiscuous binding to class II major histocompatibility complex molecules inhibits T-cell proliferative responses to major and minor histocompatibility antigens in vitro and confers the capacity to prevent murine graft-versus-host disease in vivo.
-
A systematic review of methodology applied during preclinical anesthetic neurotoxicity studies: important issues and lessons relevant to the design of future clinical research.
-
A systems genetics approach identifies Trp53inp2 as a link between cardiomyocyte glucose utilization and hypertrophic response.
-
A tamoxifen inducible knock-in allele for investigation of E2A function.
-
A targeted and adjuvanted nanocarrier lowers the effective dose of liposomal amphotericin B and enhances adaptive immunity in murine cutaneous leishmaniasis.
-
A technique for serial spermatozoa collection in mice.
-
A telomerase-immortalized primary human prostate cancer clonal cell line with neoplastic phenotypes.
-
A tenascin knockout with a phenotype.
-
A threshold for central T cell tolerance to an inducible serum protein
-
A time-course study of actively stained mouse brains: Diffusion tensor imaging parameters and connectomic stability over 1 year.
-
A timecourse analysis of systemic and gonadal effects of temperature on sexual development of the red-eared slider turtle Trachemys scripta elegans.
-
A toll-like receptor 2 pathway regulates the Ppargc1a/b metabolic co-activators in mice with Staphylococcal aureus sepsis.
-
A transcriptional repressor of osteopontin expression in the 4T1 murine breast cancer cell line.
-
A transcriptional signature accurately identifies Aspergillus Infection across healthy and immunosuppressed states.
-
A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex.
-
A transformation from temporal to ensemble coding in a model of piriform cortex.
-
A transgenic DND1GFP fusion allele reports in vivo expression and RNA-binding targets in undifferentiated mouse germ cells†.
-
A transgenic mouse prostate cancer model.
-
A transgenic toolkit for visualizing and perturbing microtubules reveals unexpected functions in the epidermis.
-
A translatable predictor of human radiation exposure.
-
A translational bridge between mouse and human models of learned safety.
-
A trithiol bifunctional chelate for 72,77As: A matched pair theranostic complex with high in vivo stability.
-
A truncated isoform of c-Mpl with an essential C-terminal peptide targets the full-length receptor for degradation.
-
A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS.
-
A tumor-intrinsic PD-L1/NLRP3 inflammasome signaling pathway drives resistance to anti-PD-1 immunotherapy.
-
A two-phase innate host response to alphavirus infection identified by mRNP-tagging in vivo.
-
A tyrosine hydroxylase-yellow fluorescent protein knock-in reporter system labeling dopaminergic neurons reveals potential regulatory role for the first intron of the rodent tyrosine hydroxylase gene.
-
A tyrosine kinase physically associates with the beta-subunit of the human IL-2 receptor.
-
A uniform human Wnt expression library reveals a shared secretory pathway and unique signaling activities.
-
A unique chromosomal rearrangement in the Cryptococcus neoformans var. grubii type strain enhances key phenotypes associated with virulence.
-
A unique pathway for the plasma elimination of alpha 2-antiplasmin-protease complexes in mice.
-
A unique role of the DNA fragmentation factor in maintaining genomic stability.
-
A validated regulatory network for Th17 cell specification.
-
A versatile oblique plane microscope for large-scale and high-resolution imaging of subcellular dynamics.
-
A versatile system to record cell-cell interactions.
-
A vital role for interleukin-21 in the control of a chronic viral infection.
-
A wireless multi-channel recording system for freely behaving mice and rats.
-
A work-performing heart preparation for myocardial performance analysis in murine hearts.
-
A20 in Myeloid Cells Protects Against Hypertension by Inhibiting Dendritic Cell-Mediated T-Cell Activation.
-
A20 modulates lipid metabolism and energy production to promote liver regeneration.
-
A20 protects mice from D-galactosamine/lipopolysaccharide acute toxic lethal hepatitis.
-
A20 protects mice from lethal liver ischemia/reperfusion injury by increasing peroxisome proliferator-activated receptor-alpha expression.
-
A20 protects mice from lethal radical hepatectomy by promoting hepatocyte proliferation via a p21waf1-dependent mechanism.
-
AAV CRISPR editing rescues cardiac and muscle function for 18 months in dystrophic mice.
-
AAV vector-mediated reversal of hypoglycemia in canine and murine glycogen storage disease type Ia.
-
AAV-CNS matters turn from gray to white.
-
AAV9 Edits Muscle Stem Cells in Normal and Dystrophic Adult Mice.
-
AAV9 gene replacement therapy for respiratory insufficiency in very-long chain acyl-CoA dehydrogenase deficiency.
-
ABC Transporter Inhibition Plus Dexamethasone Enhances the Efficacy of Convection Enhanced Delivery in H3.3K27M Mutant Diffuse Intrinsic Pontine Glioma.
-
ABCB5 is a limbal stem cell gene required for corneal development and repair.
-
ABCs of erythroid mitochondrial iron uptake.
-
ABI2-deficient mice exhibit defective cell migration, aberrant dendritic spine morphogenesis, and deficits in learning and memory.
-
ABL allosteric inhibitors synergize with statins to enhance apoptosis of metastatic lung cancer cells.
-
ABL kinase inhibition promotes lung regeneration through expansion of an SCGB1A1+ SPC+ cell population following bacterial pneumonia.
-
ABL kinases promote breast cancer osteolytic metastasis by modulating tumor-bone interactions through TAZ and STAT5 signaling.
-
ACE and ACE2 activity in diabetic mice.
-
ACE-inhibition increases podocyte number in experimental glomerular disease independent of proliferation.
-
ACTH receptors in the adrenal: specific binding of ACTH-125I and its relation to adenyl cyclase.
-
ACTL6A Is Co-Amplified with p63 in Squamous Cell Carcinoma to Drive YAP Activation, Regenerative Proliferation, and Poor Prognosis.
-
ACVR1 R206H cooperates with H3.1K27M in promoting diffuse intrinsic pontine glioma pathogenesis.
-
ADAM10 is essential for proteolytic activation of Notch during thymocyte development.
-
ADAM10-Dependent Signaling Through Notch1 and Notch4 Controls Development of Organ-Specific Vascular Beds.
-
ADAM12: a genetic modifier of preclinical peripheral arterial disease.
-
ADAMTS metalloproteases generate active versican fragments that regulate interdigital web regression.
-
AID expression during B-cell development: searching for answers.
-
AJAP1 expression modulates glioma cell motility and correlates with tumor growth and survival.
-
ALDH activity selectively defines an enhanced tumor-initiating cell population relative to CD133 expression in human pancreatic adenocarcinoma.
-
ALDH1L2 is the mitochondrial homolog of 10-formyltetrahydrofolate dehydrogenase.
-
ALK5 phosphorylation of the endoglin cytoplasmic domain regulates Smad1/5/8 signaling and endothelial cell migration.
-
ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects.
-
ALSUntangled #63: ketogenic diets.
-
ALSUntangled #65: glucocorticoid corticosteroids.
-
ALSUntangled No. 34: GM604.
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ALSUntangled No. 35: Hyperbaric Oxygen Therapy.
-
ALSUntangled No. 47: RT001.
-
AMH induces mesonephric cell migration in XX gonads.
-
AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: evidence that sn-glycerol-3-phosphate acyltransferase is a novel target.
-
AMPK Alpha-1 Intrinsically Regulates the Function and Differentiation of Tumor Myeloid-Derived Suppressor Cells.
-
AMPK and substrate availability regulate creatine transport in cultured cardiomyocytes.
-
ANG II receptor blockade prevents ventricular hypertrophy and ANF gene expression with pressure overload in mice.
-
ANK2 autism mutation targeting giant ankyrin-B promotes axon branching and ectopic connectivity.
-
APOBEC Mutagenesis Inhibits Breast Cancer Growth through Induction of T cell-Mediated Antitumor Immune Responses.
-
APOE Genotype Differentially Modulates Effects of Anti-Aβ, Passive Immunization in APP Transgenic Mice.
-
APOE Isoforms Control Pathogenic Subretinal Inflammation in Age-Related Macular Degeneration.
-
APOE and the regulation of microglial nitric oxide production: a link between genetic risk and oxidative stress.
-
APOE genotype affects outcome in a murine model of sepsis: implications for a new treatment strategy.
-
APOE genotype and an ApoE-mimetic peptide modify the systemic and central nervous system inflammatory response.
-
APOE genotype regulates pathology and disease progression in synucleinopathy.
-
APOE genotype-specific differences in human and mouse macrophage nitric oxide production.
-
APOE genotype-specific differences in the innate immune response.
-
APOE-mimetic peptides reduce behavioral deficits, plaques and tangles in Alzheimer's disease transgenics.
-
APOE2 is associated with longevity independent of Alzheimer's disease.
-
APOE4-VLDL inhibits the HDL-activated phosphatidylinositol 3-kinase/Akt Pathway via the phosphoinositol phosphatase SHIP2.
-
APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1.
-
APOL1 variants increase risk for FSGS and HIVAN but not IgA nephropathy.
-
APOL1-G0 or APOL1-G2 Transgenic Models Develop Preeclampsia but Not Kidney Disease.
-
APOL1-G0 protects podocytes in a mouse model of HIV-associated nephropathy.
-
ARHGEF26 enhances Salmonella invasion and inflammation in cells and mice.
-
ARID1A Is Essential for Endometrial Function during Early Pregnancy.
-
ARID1A and PGR proteins interact in the endometrium and reveal a positive correlation in endometriosis.
-
ASCL1 represses a SOX9+ neural crest stem-like state in small cell lung cancer.
-
ASH1L Links Histone H3 Lysine 36 Dimethylation to MLL Leukemia.
-
ASL Metabolically Regulates Tyrosine Hydroxylase in the Nucleus Locus Coeruleus.
-
ASTN2 modulates synaptic strength by trafficking and degradation of surface proteins.
-
AT1 receptors in the collecting duct directly modulate the concentration of urine.
-
AT1A angiotensin receptors in the renal proximal tubule regulate blood pressure.
-
AT2 receptor and vascular smooth muscle cell differentiation in vascular development.
-
ATDC/TRIM29 phosphorylation by ATM/MAPKAP kinase 2 mediates radioresistance in pancreatic cancer cells.
-
ATM Paradoxically Promotes Oncogenic Transformation via Transcriptional Reprogramming.
-
ATM binds to beta-adaptin in cytoplasmic vesicles.
-
ATM deficiency promotes progression of CRPC by enhancing Warburg effect.
-
ATM inhibition enhances cancer immunotherapy by promoting mtDNA leakage and cGAS/STING activation.
-
ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS.
-
ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage.
-
ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome.
-
ATP-binding cassette transporter G1 negatively regulates thymocyte and peripheral lymphocyte proliferation.
-
ATR functions as a gene dosage-dependent tumor suppressor on a mismatch repair-deficient background.
-
ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses.
-
Abelson virus abrogation of interleukin-3 dependence in a lymphoid cell line.
-
Aberrant Otx2 expression enhances migration and induces ectopic proliferation of hindbrain neuronal progenitor cells.
-
Aberrant cortical development is driven by impaired cell cycle and translational control in a DDX3X syndrome model.
-
Aberrant methylation and loss of CADM2 tumor suppressor expression is associated with human renal cell carcinoma tumor progression.
-
Aberrant responses in social interaction of dopamine transporter knockout mice.
-
Abeta42 neurotoxicity in primary co-cultures: effect of apoE isoform and Abeta conformation.
-
Abi3bp is a multifunctional autocrine/paracrine factor that regulates mesenchymal stem cell biology.
-
Abl Kinases Regulate HGF/Met Signaling Required for Epithelial Cell Scattering, Tubulogenesis and Motility.
-
Abl family kinases modulate T cell-mediated inflammation and chemokine-induced migration through the adaptor HEF1 and the GTPase Rap1.
-
Abl family kinases regulate FcγR-mediated phagocytosis in murine macrophages.
-
Abl family kinases regulate endothelial barrier function in vitro and in mice.
-
Abl interactor 1 (Abi-1) wave-binding and SNARE domains regulate its nucleocytoplasmic shuttling, lamellipodium localization, and wave-1 levels.
-
Abl kinases are required for invadopodia formation and chemokine-induced invasion.
-
Abl kinases regulate actin comet tail elongation via an N-WASP-dependent pathway.
-
Abl kinases regulate autophagy by promoting the trafficking and function of lysosomal components.
-
Abl tyrosine kinases are required for infection by Shigella flexneri.
-
Abl tyrosine kinases regulate cell-cell adhesion through Rho GTPases.
-
Abl-interactor-1 (Abi1) has a role in cardiovascular and placental development and is a binding partner of the alpha4 integrin.
-
Ablation of Sirtuin5
in the postnatal mouse heart results in protein succinylation and normal survival in response to chronic pressure overload.
-
Ablation of c-FLIP in hepatocytes enhances death-receptor mediated apoptosis and toxic liver injury in vivo.
-
Ablation of calcineurin Aβ reveals hyperlipidemia and signaling cross-talks with phosphodiesterases.
-
Ablation of dihydroceramide desaturase 1, a therapeutic target for the treatment of metabolic diseases, simultaneously stimulates anabolic and catabolic signaling.
-
Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy.
-
Ablation of the leptin receptor in myeloid cells impairs pulmonary clearance of Streptococcus pneumoniae and alveolar macrophage bactericidal function.
-
Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule.
-
Abnormal cardiac Na(+) channel properties and QT heart rate adaptation in neonatal ankyrin(B) knockout mice.
-
Abnormal cerebellar signaling induces dystonia in mice.
-
Abnormal iron deposition in renal cells in the rat with chronic angiotensin II administration.
-
Abnormal joint and bone wound healing in hemophilia mice is improved by extending factor IX activity after hemarthrosis.
-
Abnormal mouse lung alveolarization caused by Smad3 deficiency is a developmental antecedent of centrilobular emphysema.
-
Abnormal muscle spindle innervation and large-fiber neuropathy in diabetic mice.
-
Abnormal osmotic regulation in trpv4-/- mice.
-
Abnormal parathyroid function in the X-linked hypophosphatemic mouse.
-
Abnormal parathyroid hormone stimulation of 25-hydroxyvitamin D-1 alpha-hydroxylase activity in the hypophosphatemic mouse. Evidence for a generalized defect of vitamin D metabolism.
-
Abnormal production of interleukin-1 by microglia from trisomy 16 mice.
-
Abnormal regulation of renal 25-hydroxyvitamin D-1 alpha-hydroxylase activity in the X-linked hypophosphatemic mouse.
-
Abnormal water metabolism in mice lacking the type 1A receptor for ANG II.
-
Abrogation of adenosine A1 receptor signalling improves metabolic regulation in mice by modulating oxidative stress and inflammatory responses.
-
Absence of carboxypeptidase E leads to adult hippocampal neuronal degeneration and memory deficits.
-
Absence of donor MHC antigen expression ameliorates chronic kidney allograft rejection.
-
Absence of interferon-gamma-inducible gene IGTP does not significantly alter the development of chagasic cardiomyopathy in mice infected with Trypanosoma cruzi (Brazil strain).
-
Absence of macrophage involvement in the passive serum therapy of Friend leukemia virus-induced disease.
-
Absence of posttraumatic arthritis following intraarticular fracture in the MRL/MpJ mouse.
-
Absence of progeria-like disease phenotypes in knock-in mice expressing a non-farnesylated version of progerin.
-
Absence of synaptic regulation by phosducin in retinal slices.
-
Absence of teratogenic effects of progesterone on the developing genital tract of the human female fetus.
-
Absence of the CAAX endoprotease Rce1: effects on cell growth and transformation.
-
Absence of the RGS9.Gbeta5 GTPase-activating complex in photoreceptors of the R9AP knockout mouse.
-
Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease.
-
Absence of tubuloglomerular feedback responses in AT1A receptor-deficient mice.
-
Abundant androgen regulated mRNAs in mouse submandibular gland: cell-free translation of renin precursor mRNA.
-
Abundant expression of ponsin, a focal adhesion protein, in lens and downregulation of its expression by impaired cytoskeletal signaling.
-
Accelerated induction of experimental allergic encephalomyelitis in PL/J mice by a non-V beta 8-specific superantigen.
-
Accelerated neural differentiation of mouse embryonic stem cells on aligned GYIGSR-functionalized nanofibers.
-
Accelerated neurodegeneration through chaperone-mediated oligomerization of tau.
-
Accelerated wound healing by injectable star poly(ethylene glycol)-b-poly(propylene sulfide) scaffolds loaded with poorly water-soluble drugs.
-
Accelerating quantitative susceptibility imaging acquisition using compressed sensing.
-
Acceleration of mammary neoplasia in transforming growth factor alpha transgenic mice by 7,12-dimethylbenzanthracene.
-
Accessory subunit KChIP2 modulates the cardiac L-type calcium current.
-
Acclimation of C2C12 myoblasts to physiological glucose concentrations for in vitro diabetes research.
-
Accumulation of Ubiquitin and Sequestosome-1 Implicate Protein Damage in Diacetyl-Induced Cytotoxicity.
-
Accumulation of duct cells with activated YAP parallels fibrosis progression in non-alcoholic fatty liver disease.
-
Accumulation of hedgehog-responsive progenitors parallels alcoholic liver disease severity in mice and humans.
-
Accumulation of natural killer T cells in progressive nonalcoholic fatty liver disease.
-
Accurate in vivo
tumor detection using plasmonic-enhanced shifted-excitation Raman difference spectroscopy (SERDS).
-
Accurate temperature imaging based on intermolecular coherences in magnetic resonance.
-
Acetalated Dextran Microparticles for Codelivery of STING and TLR7/8 Agonists.
-
Acetaminophen normalizes glucose homeostasis in mouse models for diabetes.
-
Acetate Production from Glucose and Coupling to Mitochondrial Metabolism in Mammals.
-
Acetyl-CoA metabolism drives epigenome change and contributes to carcinogenesis risk in fatty liver disease.
-
Acetylcholine Modulates Cerebellar Granule Cell Spiking by Regulating the Balance of Synaptic Excitation and Inhibition.
-
Acetylcholine promotes the proliferation and collagen gene expression of myofibroblastic hepatic stellate cells.
-
Acetylcholinesterase Inhibitors Are Associated with Reduced Fracture Risk among Older Veterans with Dementia.
-
Acetylenics. 2. Synthesis and pharmacology of certain N,N-diakyl-3-phenylpropyn-2-amines. Some analogues with tryptamine-like behavioral effects in mice.
-
Acly Deficiency Enhances Myelopoiesis through Acetyl Coenzyme A and Metabolic-Epigenetic Cross-Talk.
-
Acquired expression of periostin by human breast cancers promotes tumor angiogenesis through up-regulation of vascular endothelial growth factor receptor 2 expression.
-
Acquisition of a functional T cell receptor during T lymphocyte development is enforced by HEB and E2A transcription factors.
-
Acquisition of response thresholds for timed performance is regulated by a calcium-responsive transcription factor, CaRF.
-
Acrylic fragmentation in total hip replacements and its biological consequences.
-
Actin cytoskeletal disruption following cryopreservation alters the biodistribution of human mesenchymal stromal cells in vivo.
-
Actin-related protein2/3 complex regulates tight junctions and terminal differentiation to promote epidermal barrier formation.
-
Action potential-coupled Rho GTPase signaling drives presynaptic plasticity.
-
Actions of thrombin in the interstitium.
-
Activated Akt promotes increased resting T cell size, CD28-independent T cell growth, and development of autoimmunity and lymphoma.
-
Activated B cells modified by electroporation of multiple mRNAs encoding immune stimulatory molecules are comparable to mature dendritic cells in inducing in vitro antigen-specific T-cell responses.
-
Activated c-Abl is degraded by the ubiquitin-dependent proteasome pathway.
-
Activated protein C preserves functional islet mass after intraportal transplantation: a novel link between endothelial cell activation, thrombosis, inflammation, and islet cell death.
-
Activated signal transducer and activator of transcription (STAT) 3: localization in focal adhesions and function in ovarian cancer cell motility.
-
Activating an adaptive immune response from a hydrogel scaffold imparts regenerative wound healing.
-
Activation and repression of mammalian gene expression by the c-myc protein.
-
Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP2.
-
Activation of Akt/PDK signaling in macrophages upon binding of receptor-recognized forms of alpha2-macroglobulin to its cellular receptor: effect of silencing the CREB gene.
-
Activation of Cardiac Fibroblast Growth Factor Receptor 4 Causes Left Ventricular Hypertrophy.
-
Activation of ENS Circuits in Mouse Colon: Coordination in the Mouse Colonic Motor Complex as a Robust, Distributed Control System.
-
Activation of GPR37 in macrophages confers protection against infection-induced sepsis and pain-like behaviour in mice.
-
Activation of Galpha q-coupled signaling pathways in glomerular podocytes promotes renal injury.
-
Activation of Glutamatergic Fibers in the Anterior NAc Shell Modulates Reward Activity in the aNAcSh, the Lateral Hypothalamus, and Medial Prefrontal Cortex and Transiently Stops Feeding.
-
Activation of MEF2 by muscle activity is mediated through a calcineurin-dependent pathway.
-
Activation of NADPH oxidase 1 increases intracellular calcium and migration of smooth muscle cells.
-
Activation of Notch1 synergizes with multiple pathways in promoting castration-resistant prostate cancer.
-
Activation of Nrf2 Is Required for Normal and ChREBPα-Augmented Glucose-Stimulated β-Cell Proliferation.
-
Activation of RalA is critical for Ras-induced tumorigenesis of human cells.
-
Activation of Rod Input in a Model of Retinal Degeneration Reverses Retinal Remodeling and Induces Formation of Functional Synapses and Recovery of Visual Signaling in the Adult Retina.
-
Activation of Slo1 BK channels by Mg2+ coordinated between the voltage sensor and RCK1 domains.
-
Activation of a nerve injury transcriptional signature in airway-innervating sensory neurons after lipopolysaccharide-induced lung inflammation.
-
Activation of a phosphotyrosine phosphatase by tyrosine phosphorylation.
-
Activation of arterial wall dendritic cells and breakdown of self-tolerance in giant cell arteritis.
-
Activation of cyclophosphamide for in vitro testing of cell sensitivity.
-
Activation of decidual invariant natural killer T cells promotes lipopolysaccharide-induced preterm birth.
-
Activation of fibroblast growth factor (FGF) receptors by recombinant human FGF-5.
-
Activation of glycolysis and apoptosis in glycogen storage disease type Ia.
-
Activation of hedgehog signaling during fracture repair enhances osteoblastic-dependent matrix formation.
-
Activation of interleukin 4- and interleukin 6-secreting cells by HIV-specific synthetic peptides.
-
Activation of matrix metalloproteinases following anti-Aβ immunotherapy; implications for microhemorrhage occurrence.
-
Activation of messenger-independent protein kinases in wild-type and phorbol ester-resistant EL4 thymoma cells.
-
Activation of mitochondrial biogenesis by heme oxygenase-1-mediated NF-E2-related factor-2 induction rescues mice from lethal Staphylococcus aureus sepsis.
-
Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro.
-
Activation of nuclear receptor CAR ameliorates diabetes and fatty liver disease.
-
Activation of specific interneurons improves V1 feature selectivity and visual perception.
-
Activation of swelling-activated chloride current by tumor necrosis factor-alpha requires ClC-3-dependent endosomal reactive oxygen production.
-
Activation of the ATF6 branch of the unfolded protein response in neurons improves stroke outcome.
-
Activation of the NLRP3 inflammasome by intracellular poly I:C.
-
Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer.
-
Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumors.
-
Activation of the XBP1s/O-GlcNAcylation Pathway Improves Functional Outcome After Cardiac Arrest and Resuscitation in Young and Aged Mice.
-
Activation of the mTOR Pathway by Oxaliplatin in the Treatment of Colorectal Cancer Liver Metastasis.
-
Activation of the murine EP3 receptor for PGE2 inhibits cAMP production and promotes platelet aggregation.
-
Activation of toll-like receptor 4 is necessary for trauma hemorrhagic shock-induced gut injury and polymorphonuclear neutrophil priming.
-
Activation of transcription factors activator protein-1 and nuclear factor-kappaB by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
-
Activation-induced cytidine deaminase expression and activity in the absence of germinal centers: insights into hyper-IgM syndrome.
-
Activation-induced cytidine deaminase mediates central tolerance in B cells.
-
Activation-induced endocytosis of the raft-associated transmembrane adaptor protein LAB/NTAL in B lymphocytes: evidence for a role in internalization of the B cell receptor.
-
Active immunization using dendritic cells mixed with tumor cells inhibits the growth of primary breast cancer.
-
Active immunization with tumor cells transduced by a novel AAV plasmid-based gene delivery system.
-
Active immunotherapy of pancreatic cancer with tumor cells genetically engineered to secrete multiple cytokines.
-
Active immunotherapy with transiently transfected cytokine-secreting tumor cells inhibits breast cancer metastases in tumor-bearing animals.
-
Active learning of cortical connectivity from two-photon imaging data.
-
Active staining of mouse embryos for magnetic resonance microscopy.
-
Activin enhances skin tumourigenesis and malignant progression by inducing a pro-tumourigenic immune cell response.
-
Activity and cellular functions of the deubiquitinating enzyme and polyglutamine disease protein ataxin-3 are regulated by ubiquitination at lysine 117.
-
Activity and stability of recombinant bifunctional rearranged and monofunctional domains of ATP-sulfurylase and adenosine 5'-phosphosulfate kinase.
-
Activity level, apoptosis, and development of cachexia in Apc(Min/+) mice.
-
Activity of 9-dimethylaminomethyl-10-hydroxycamptothecin against pediatric and adult central nervous system tumor xenografts.
-
Activity of VNP40101M (Cloretazine) in the treatment of CNS tumor xenografts in athymic mice.
-
Activity of a Py-Im polyamide targeted to the estrogen response element.
-
Activity of and effect of subcutaneous treatment with the broad-spectrum antiviral lectin griffithsin in two laboratory rodent models.
-
Activity of irofulven (6-hydroxymethylacylfulvene) in the treatment of glioblastoma multiforme-derived xenografts in athymic mice.
-
Activity of temozolomide in the treatment of central nervous system tumor xenografts.
-
Activity-dependent PSA expression regulates inhibitory maturation and onset of critical period plasticity.
-
Activity-dependent expression of ELAV/Hu RBPs and neuronal mRNAs in seizure and cocaine brain.
-
Activity-dependent expression of RNA binding protein HuD and its association with mRNAs in neurons.
-
Activity-induced remodeling of olfactory bulb microcircuits revealed by monosynaptic tracing.
-
Acupuncture Resolves Persistent Pain and Neuroinflammation in a Mouse Model of Chronic Overlapping Pain Conditions.
-
Acute DNA damage activates the tumour suppressor p53 to promote radiation-induced lymphoma.
-
Acute IL-4 Governs Pathogenic T Cell Responses during Leishmania major
Infection.
-
Acute N-Acetylcysteine Administration Ameliorates Loss of Olfactory Neurons Following Experimental Injury In Vivo.
-
Acute and chronic B cell depletion disrupts CD4+ and CD8+ T cell homeostasis and expansion during acute viral infection in mice.
-
Acute ethanol administration downregulates human immunodeficiency virus-1 glycoprotein 120-induced KC and RANTES production by murine Kupffer cells and splenocytes.
-
Acute graft-vs-host disease: pathobiology and management.
-
Acute in vivo genetic rescue demonstrates that phosphorylation of RIM1alpha serine 413 is not required for mossy fiber long-term potentiation.
-
Acute inflammatory response via neutrophil activation protects against the development of chronic pain.
-
Acute joint pathology and synovial inflammation is associated with increased intra-articular fracture severity in the mouse knee.
-
Acute loss of adipose tissue-derived adiponectin triggers immediate metabolic deterioration in mice.
-
Acute morphine activates satellite glial cells and up-regulates IL-1β in dorsal root ganglia in mice via matrix metalloprotease-9.
-
Acute morphine induces matrix metalloproteinase-9 up-regulation in primary sensory neurons to mask opioid-induced analgesia in mice.
-
Acute murine cytomegalovirus disrupts established transplantation tolerance and causes recipient allo-sensitization.
-
Acute organ failure following the loss of anti-apoptotic cellular FLICE-inhibitory protein involves activation of innate immune receptors.
-
Acute pancreatitis induces FasL gene expression and apoptosis in the liver.
-
Acute post-injury blockade of α2δ-1 calcium channel subunits prevents pathological autonomic plasticity after spinal cord injury.
-
Acute respiratory infection with mouse adenovirus type 1.
-
Acute restraint stress redirects prefrontal cortex circuit function through mGlu5
receptor plasticity on somatostatin-expressing interneurons.
-
Acute suppression of insulin resistance-associated hepatic miR-29 in vivo improves glycemic control in adult mice.
-
Acute tissue injury activates satellite cells and promotes sarcoma formation via the HGF/c-MET signaling pathway.
-
Acute tubular necrosis. An experimental model detailing the biochemical events accompanying renal injury and recovery.
-
Acyl derivatives of demethylpenclomedine, an antitumor-active, non-neurotoxic metabolites of penclomedine.
-
Acylation of Superoxide Dismutase 1 (SOD1) at K122 Governs SOD1-Mediated Inhibition of Mitochondrial Respiration.
-
Ad-IRF-1 induces apoptosis in esophageal adenocarcinoma.
-
Adam10 is essential for early embryonic cardiovascular development.
-
Adaptation after small bowel resection is attenuated by sialoadenectomy: the role for endogenous epidermal growth factor.
-
Adaptation in a mouse colony monoassociated with Escherichia coli K-12 for more than 1,000 days.
-
Adaptation of an ICAM-1-tropic enterovirus to the mouse respiratory tract.
-
Adaptive Activation of a Stress Response Pathway Improves Learning and Memory Through Gs and β-Arrestin-1-Regulated Lactate Metabolism.
-
Adaptive evolution drives the diversification of zinc-finger binding domains.
-
Adaptive mechanisms that preserve cardiac function in mice without myoglobin.
-
Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints.
-
Addition of a second, different allogeneic graft accelerates white cell and platelet engraftment after T-cell-depleted bone marrow transplantation.
-
Additive and synergistic interactions of monoclonal antibodies and immunotoxins reactive with breast and ovarian cancer.
-
Additive estrogenic activities of a binary mixture of 2',4',6'-trichloro- and 2',3',4',5'-tetrachloro-4-biphenylol.
-
Addressing cell-sourcing limitations with gene therapy.
-
Adeno-Associated Virus-Mediated Gene Therapy in the Mashlool, Atp1a3Mashl/+, Mouse Model of Alternating Hemiplegia of Childhood.
-
Adeno-associated viral vectors based on serotype 3b use components of the fibroblast growth factor receptor signaling complex for efficient transduction.
-
Adeno-associated virus serotypes: vector toolkit for human gene therapy.
-
Adeno-associated virus type 2 contains an integrin alpha5beta1 binding domain essential for viral cell entry.
-
Adeno-associated virus-delivered artificial microRNA extends survival and delays paralysis in an amyotrophic lateral sclerosis mouse model.
-
Adeno-associated virus-mediated antiangiogenic gene therapy with thrombospondin-1 type 1 repeats and endostatin.
-
Adenomas induced by polycyclic aromatic hydrocarbons in strain A/J mouse lung correlate with time-integrated DNA adduct levels.
-
Adenosine-deaminase-deficient mice die perinatally and exhibit liver-cell degeneration, atelectasis and small intestinal cell death.
-
Adenoviral expression of NHERF-1 in NHERF-1 null mouse renal proximal tubule cells restores Npt2a regulation by low phosphate media and parathyroid hormone.
-
Adenovirus F protein as a delivery vehicle for botulinum B.
-
Adenovirus-mediated antisense urokinase-type plasminogen activator receptor gene transfer reduces tumor cell invasion and metastasis in non-small cell lung cancer cell lines.
-
Adenovirus-mediated transfer of CCAAT/enhancer-binding protein-alpha identifies a dominant antiproliferative role for this isoform in hepatocytes.
-
Adenylate cyclase 7 is implicated in the biology of depression and modulation of affective neural circuitry.
-
Adenylate cyclase toxin (ACT) from Bordetella hinzii: characterization and differences from ACT of Bordetella pertussis.
-
Adhesion GPCR Latrophilin 3 regulates synaptic function of cone photoreceptors in a trans-synaptic manner.
-
Adhesion to osteopontin in the bone marrow niche regulates lymphoblastic leukemia cell dormancy.
-
Adipocyte Xbp1s overexpression drives uridine production and reduces obesity.
-
Adipogenic and lipolytic effects of chronic glucocorticoid exposure.
-
Adiponectin is essential for lipid homeostasis and survival under insulin deficiency and promotes β-cell regeneration.
-
Adiponectin preserves metabolic fitness during aging.
-
Adipose acyl-CoA synthetase-1 directs fatty acids toward beta-oxidation and is required for cold thermogenesis.
-
Adipose tissue at single-cell resolution.
-
Adipose tissue branched chain amino acid (BCAA) metabolism modulates circulating BCAA levels.
-
Adipose tissue hyaluronan production improves systemic glucose homeostasis and primes adipocytes for CL 316,243-stimulated lipolysis.
-
Adipose-specific deletion of TFAM increases mitochondrial oxidation and protects mice against obesity and insulin resistance.
-
Adjunctive β2-agonist treatment reduces glycogen independently of receptor-mediated acid α-glucosidase uptake in the limb muscles of mice with Pompe disease.
-
Adjunctive β2-agonists reverse neuromuscular involvement in murine Pompe disease.
-
Adjuvant Injections Altered the Ileal and Fecal Microbiota Differently with Changes in Immunoglobulin Isotypes and Antimycobacterial Antibody Responses.
-
Administration of a CD31-derived peptide delays the onset and significantly increases survival from lethal graft-versus-host disease.
-
Adoptive transfer of cytotoxic T lymphocytes for the treatment of transplant-associated lymphoma.
-
Adoptively transferred ex vivo expanded gammadelta-T cells mediate in vivo antitumor activity in preclinical mouse models of breast cancer.
-
Adrb2 controls glucose homeostasis by developmental regulation of pancreatic islet vasculature.
-
Adrenergic Stimulation of DUSP1 Impairs Chemotherapy Response in Ovarian Cancer.
-
Adrenergic regulation of monocyte chemotactic protein 1 leads to enhanced macrophage recruitment and ovarian carcinoma growth.
-
Adrenoceptors, uncoupling proteins, and energy expenditure.
-
Adrenomedullin improves fertility and promotes pinopodes and cell junctions in the peri-implantation endometrium.
-
Adult Lung Spheroid Cells Contain Progenitor Cells and Mediate Regeneration in Rodents With Bleomycin-Induced Pulmonary Fibrosis.
-
Adult renal mesenchymal stem cell-like cells contribute to juxtaglomerular cell recruitment.
-
Advanced glycation end-product of low density lipoprotein activates the toll-like 4 receptor pathway implications for diabetic atherosclerosis.
-
Advanced magnetic resonance imaging of cerebral cavernous malformations: part II. Imaging of lesions in murine models.
-
Advantages of mRNA amplification for microarray analysis.
-
Adynamic Bone Decreases Bone Toughness During Aging by Affecting Mineral and Matrix.
-
Aerobic exercise attenuates airway inflammatory responses in a mouse model of atopic asthma.
-
Aerobic training as an adjunctive therapy to enzyme replacement in Pompe disease.
-
Affinity-matured anti-glycoprotein NMB recombinant immunotoxins targeting malignant gliomas and melanomas.
-
Affinity-matured recombinant immunotoxin targeting gangliosides 3'-isoLM1 and 3',6'-isoLD1 on malignant gliomas.
-
Age Correlates with Response to Anti-PD1, Reflecting Age-Related Differences in Intratumoral Effector and Regulatory T-Cell Populations.
-
Age as an independent risk factor for severity of experimental choroidal neovascularization.
-
Age-Dependent Effects of Immunoproteasome Deficiency on Mouse Adenovirus Type 1 Pathogenesis.
-
Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis.
-
Age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites.
-
Age-dependent alterations of peritoneal exudate macrophages in autoimmune-prone and autoimmune-resistant mouse strains.
-
Age-dependent retinal iron accumulation and degeneration in hepcidin knockout mice.
-
Age-dependent sexual dimorphism in cognition and stress response in the 3xTg-AD mice.
-
Age-related changes in eye morphology and aqueous humor dynamics in DBA/2J mice using contrast-enhanced ocular MRI.
-
Age-related changes in the cellular composition and epithelial organization of the mouse trachea.
-
Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration.
-
Age-related efficacy with an AAV vector in Fabry disease mice.
-
Aged G Protein-Coupled Receptor Kinase 3 (Grk3)-Deficient Mice Exhibit Enhanced Osteoclastogenesis and Develop Bone Lesions Analogous to Human Paget's Disease of Bone.
-
Ager-CreERT2: A New Genetic Tool for Studying Lung Alveolar Development, Homeostasis, and Repair.
-
Aggresome disruption: a novel strategy to enhance bortezomib-induced apoptosis in pancreatic cancer cells.
-
Aggressive fibromatosis (desmoid tumor) is derived from mesenchymal progenitor cells.
-
Aging Is Associated With Impaired Activation of Protein Homeostasis-Related Pathways After Cardiac Arrest in Mice.
-
Aging and neoplasia.
-
Aging and obesity prime the methylome and transcriptome of adipose stem cells for disease and dysfunction.
-
Aging and reactivation of latent murine cytomegalovirus.
-
Aging reduces liver resiliency by dysregulating Hedgehog signaling.
-
Aging-related atherosclerosis is exacerbated by arterial expression of tumor necrosis factor receptor-1: evidence from mouse models and human association studies.
-
Agonist-dependent phosphorylation of the mouse delta-opioid receptor: involvement of G protein-coupled receptor kinases but not protein kinase C.
-
Agonist-dependent recruitment of phosphoinositide 3-kinase to the membrane by beta-adrenergic receptor kinase 1. A role in receptor sequestration.
-
Agonist-specific regulation of delta-opioid receptor trafficking by G protein-coupled receptor kinase and beta-arrestin.
-
Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity.
-
Agonists of G-Protein-Coupled Odorant Receptors Are Predicted from Chemical Features.
-
Airway epithelial progenitors are region specific and show differential responses to bleomycin-induced lung injury.
-
Airway inflammation and responsiveness in prostaglandin H synthase-deficient mice exposed to bacterial lipopolysaccharide.
-
Airway smooth muscle dysfunction in Pompe (Gaa-/- ) mice.
-
Airway smooth muscle relaxation is impaired in mice lacking the p47phox subunit of NAD(P)H oxidase.
-
Airway-specific inducible transgene expression using aerosolized doxycycline.
-
Akt activation protects hippocampal neurons from apoptosis by inhibiting transcriptional activity of p53.
-
Akt is required for Stat5 activation and mammary differentiation.
-
Akt requires glucose metabolism to suppress puma expression and prevent apoptosis of leukemic T cells.
-
Akt-dependent and -independent mechanisms of mTOR regulation in cancer.
-
Akt-dependent glucose metabolism promotes Mcl-1 synthesis to maintain cell survival and resistance to Bcl-2 inhibition.
-
Akt-directed glucose metabolism can prevent Bax conformation change and promote growth factor-independent survival.
-
Akt/protein kinase B promotes organ growth in transgenic mice.
-
Akt1 and Akt2 are required for alphabeta thymocyte survival and differentiation.
-
Akt1 and Akt2 promote peripheral B-cell maturation and survival.
-
Akt1 deletion prevents lung tumorigenesis by mutant K-ras.
-
Aldehyde dehydrogenase inhibition blocks mucosal fibrosis in human and mouse ocular scarring.
-
Aldolase B-Mediated Fructose Metabolism Drives Metabolic Reprogramming of Colon Cancer Liver Metastasis.
-
Aldosterone Exposure Causes Increased Retinal Edema and Severe Retinopathy Following Laser-Induced Retinal Vein Occlusion in Mice.
-
Aldosterone, ion channels, and sudden death: another piece of the circle?
-
Aldosterone-Induced Vascular Remodeling and Endothelial Dysfunction Require Functional Angiotensin Type 1a Receptors.
-
Aldosterone-induced activation of signaling pathways requires activity of angiotensin type 1a receptors.
-
Alginate encapsulation is a highly reproducible method for tumor cell implantation in dorsal skinfold chambers.
-
Aligning animal models with clinical epilepsy: where to begin?
-
All Staphylococcus aureus bacteraemia-inducing strains can cause infective endocarditis: Results of GWAS and experimental animal studies.
-
Allele-specific regulation of TCR beta variable gene segment chromatin structure.
-
Allelic Imbalance Is a Prevalent and Tissue-Specific Feature of the Mouse Transcriptome.
-
Allelic exclusion of mouse T cell receptor alpha chains occurs at the time of thymocyte TCR up-regulation.
-
Allelic exclusion of the T cell receptor alpha-chain: developmental regulation of a post-translational event.
-
Allelic exclusion of the TCR alpha-chain is an active process requiring TCR-mediated signaling and c-Cbl.
-
Allergen-induced airway disease is mouse strain dependent.
-
Allergic inflammation induces a persistent mechanistic switch in thromboxane-mediated airway constriction in the mouse.
-
Allergic lung responses are increased in prostaglandin H synthase-deficient mice.
-
Allo-Specific Humoral Responses: New Methods for Screening Donor-Specific Antibody and Characterization of HLA-Specific Memory B Cells.
-
Allocation of epiblast cells to germ layer derivatives during mouse gastrulation as studied with a retroviral vector.
-
Allogeneic Stem-Cell Transplantation - A T-Cell Balancing ACT.
-
Allogeneic memory T cell response.
-
Allogeneic splenocyte transfer and lipopolysaccharide inhalations induce differential T cell expansion and lung injury: a novel model of pulmonary graft-versus-host disease.
-
Allograft dendritic cell p40 homodimers activate donor-reactive memory CD8+ T cells.
-
Alloimmune lung injury induced by local innate immune activation through inhaled lipopolysaccharide.
-
Allometric scaling of decompression sickness risk in terrestrial mammals; cardiac output explains risk of decompression sickness.
-
Allospecific CD4(+) effector memory T cells do not induce graft-versus-host disease in mice.
-
Allosteric inhibitor of β-catenin selectively targets oncogenic Wnt signaling in colon cancer.
-
Alopecia in IL-10-deficient mouse pups is c-kit-dependent and can be triggered by iron deficiency.
-
Alpha 2 macroglobulin-proteinase complexes stimulate prostaglandin E2 synthesis by peritoneal macrophages.
-
Alpha 2-macroglobulin 'fast' forms inhibit superoxide production by activated macrophages.
-
Alpha 2-macroglobulin binds CpG oligodeoxynucleotides and enhances their immunostimulatory properties by a receptor-dependent mechanism.
-
Alpha-chemokine receptor blockade reduces high mobility group box 1 protein-induced lung inflammation and injury and improves survival in sepsis.
-
Alpha-fetoprotein-specific genetic immunotherapy for hepatocellular carcinoma.
-
Alpha-melanocyte-stimulating hormone suppresses antigen-stimulated T cell production of gamma-interferon.
-
Alphavirus Replicon Particle Vaccine Breaks B Cell Tolerance and Rapidly Induces IgG to Murine Hematolymphoid Tumor Associated Antigens.
-
Alphavirus replicon particles acting as adjuvants promote CD8+ T cell responses to co-delivered antigen.
-
Alphavirus replicon particles as candidate HIV vaccines.
-
Alprazolam reduces stress hyperglycemia in ob/ob mice.
-
Alterations in PKCgamma in the mouse hippocampus after prenatal exposure to heroin: a link from cell signaling to behavioral outcome.
-
Alterations in calcium channel currents underlie defective insulin secretion in a transgenic mouse.
-
Alterations in calcium metabolism in murine macrophages by the benzene metabolite 1,4-benzoquinone.
-
Alterations in cardiac adrenergic signaling and calcium cycling differentially affect the progression of cardiomyopathy.
-
Alterations in inorganic phosphate in mouse hindlimb muscles during limb disuse.
-
Alterations in macrophage phenotypes in experimental venous thrombosis.
-
Alterations in skeletal muscle fatty acid handling predisposes middle-aged mice to diet-induced insulin resistance.
-
Alterations in slow-twitch muscle phenotype in transgenic mice overexpressing the Ca2+ buffering protein parvalbumin.
-
Altered B lymphocyte function induces systemic autoimmunity in systemic sclerosis.
-
Altered Mitochondrial Homeostasis during Systemic Lupus Erythematosus Impairs Neutrophil Extracellular Trap Formation Rendering Neutrophils Ineffective at Combating Staphylococcus aureus.
-
Altered T-dependent antigen responses and development of autoimmune symptoms in mice lacking E2A in T lymphocytes.
-
Altered Twist1 and Hand2 dimerization is associated with Saethre-Chotzen syndrome and limb abnormalities.
-
Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3.
-
Altered blood pressure responses and normal cardiac phenotype in ACE2-null mice.
-
Altered cAMP levels in retinas from transgenic mice expressing a rhodopsin mutant.
-
Altered cell-averaged microviscosity of murine peritoneal macrophages undergoing activation in vivo or in vitro.
-
Altered clearance of human alpha 2-macroglobulin complexes following reaction with cis-dichlorodiamineplatinum(II).
-
Altered distribution of H60 minor H antigen-specific CD8 T cells and attenuated chronic vasculopathy in minor histocompatibility antigen mismatched heart transplantation in Cxcr3-/- mouse recipients.
-
Altered distribution of mitochondria and actin fibers in 3T3 cells cultured on microcarriers.
-
Altered expression of ganglioside phenotypes of human gliomas in vivo and in vitro.
-
Altered growth of a human neuroendocrine carcinoma line after transfection of a major histocompatibility complex class I gene.
-
Altered hepatic lymphocyte subpopulations in obesity-related murine fatty livers: potential mechanism for sensitization to liver damage.
-
Altered immune responses in apolipoprotein E-deficient mice.
-
Altered inflammatory responses in leukotriene-deficient mice.
-
Altered interaction of Cis-dichlorodiammineplatinum(II)--modified alpha 2-macroglobulin (alpha 2M) with the low density lipoprotein receptor-related protein/alpha 2M receptor but not the alpha 2M signaling receptor.
-
Altered intragraft immune responses and improved renal function in MHC class II-deficient mouse kidney allografts.
-
Altered localization of choline transporter sites in the mouse hippocampus after prenatal heroin exposure.
-
Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP.
-
Altered lymphopoiesis and immunodeficiency in miR-142 null mice.
-
Altered mGluR5-Homer scaffolds and corticostriatal connectivity in a Shank3 complete knockout model of autism.
-
Altered morphology of hippocampal dentate granule cell presynaptic and postsynaptic terminals following conditional deletion of TrkB.
-
Altered regulation of brain-derived neurotrophic factor protein in hippocampus following slice preparation.
-
Altered stored calcium release in skeletal myotubes deficient of triadin and junctin.
-
Altered synthesis of the 26-kDa heat stress protein family and thermotolerance in cell lines with elevated levels of calcium-binding proteins.
-
Altered toll-like receptor responsiveness underlies a dominant heritable defect in B cell tolerance in autoimmune New Zealand Black mice.
-
Altered trabecular bone structure and delayed cartilage degeneration in the knees of collagen VI null mice.
-
Altered urinary bladder function in mice lacking the vanilloid receptor TRPV1.
-
Altered wound healing in mice lacking a functional osteopontin gene (spp1).
-
Altering and assessing persistence of genetically modified E. coli MG1655 in the large bowel.
-
Alternative Splicing of EZH2 pre-mRNA by SF3B3 Contributes to the Tumorigenic Potential of Renal Cancer.
-
Alternative Splicing of Opioid Receptor Genes Shows a Conserved Pattern for 6TM Receptor Variants.
-
Alternative pathways for the selection of antigen-specific peripheral T cells.
-
Alternative processing of androgen-binding protein RNA transcripts in fetal rat liver. Identification of a transcript formed by trans splicing.
-
Alternative splicing in Acad8 resulting a mitochondrial defect and progressive hepatic steatosis in mice.
-
Alternative splicing of an insect sodium channel gene generates pharmacologically distinct sodium channels.
-
Alternative splicing of fibroblast growth factor receptor 2 (FGF-R2) in human prostate cancer.
-
Alternative splicing promotes tumour aggressiveness and drug resistance in African American prostate cancer.
-
Alternative splicing: a mechanism for phenotypic rescue of a common inherited defect.
-
Alternatively spliced human tissue factor promotes tumor growth and angiogenesis in a pancreatic cancer tumor model.
-
Aluminum-induced DNA synthesis in osteoblasts: mediation by a G-protein coupled cation sensing mechanism.
-
Alveolar Epithelial Cell-Derived Prostaglandin E2 Serves as a Request Signal for Macrophage Secretion of Suppressor of Cytokine Signaling 3 during Innate Inflammation.
-
Alveolar macrophage apoptosis and TNF-alpha, but not p53, expression correlate with murine response to bleomycin.
-
Alveolar proteinosis: a disease of mice and men.
-
Alveolar rhabdomyosarcoma-associated PAX3-FOXO1 promotes tumorigenesis via Hippo pathway suppression.
-
Alveolar septal structure in different species.
-
Alzheimer's Risk Factors Age, APOE Genotype, and Sex Drive Distinct Molecular Pathways.
-
Amelioration of inflammatory arthritis by targeting the pre-ligand assembly domain of tumor necrosis factor receptors.
-
Amenable epigenetic traits of dental pulp stem cells underlie high capability of xeno-free episomal reprogramming.
-
Amino acid-based Poly(ester urea) copolymer films for hernia-repair applications.
-
Amino acids stimulate cholecystokinin release through the Ca2+-sensing receptor.
-
Aminoaciduria and altered renal expression of luminal amino acid transporters in mice lacking novel gene collectrin.
-
Amitriptyline Treatment Mitigates Sepsis-Induced Tumor Necrosis Factor Expression and Coagulopathy.
-
Amplification and expression of the epidermal growth factor receptor gene in human glioma xenografts.
-
Amplification of telomeric DNA directly correlates with metastatic potential of human and murine cancers of various histological origin.
-
Amplification of the c-myc gene in human medulloblastoma cell lines and xenografts.
-
Amplified B lymphocyte CD40 signaling drives regulatory B10 cell expansion in mice.
-
Amyloid precursor protein and amyloid beta-peptide bind to ATP synthase and regulate its activity at the surface of neural cells.
-
Amyloid reduction by amyloid-beta vaccination also reduces mouse tau pathology and protects from neuron loss in two mouse models of Alzheimer's disease.
-
Amyloid-beta1-42 reduces neuronal excitability in mouse dentate gyrus.
-
An AOTF-based dual-modality hyperspectral imaging system (DMHSI) capable of simultaneous fluorescence and reflectance imaging.
-
An ARF-independent c-MYC-activated tumor suppression pathway mediated by ribosomal protein-Mdm2 Interaction.
-
An Adeno-Associated Virus-Based Toolkit for Preferential Targeting and Manipulating Quiescent Neural Stem Cells in the Adult Hippocampus.
-
An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior.
-
An Ectopic CTCF Binding Element Inhibits Tcrd Rearrangement by Limiting Contact between Vδ and Dδ Gene Segments.
-
An Efficient Method for Labeling Single Domain Antibody Fragments with 18F Using Tetrazine- Trans-Cyclooctene Ligation and a Renal Brush Border Enzyme-Cleavable Linker.
-
An Engineered Biomimetic MPER Peptide Vaccine Induces Weakly HIV Neutralizing Antibodies in Mice.
-
An Engineered Metal Sensor Tunes the Kinetics of Synaptic Transmission.
-
An Engineered Optogenetic Switch for Spatiotemporal Control of Gene Expression, Cell Differentiation, and Tissue Morphogenesis.
-
An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis.
-
An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart.
-
An FGF-WNT gene regulatory network controls lung mesenchyme development.
-
An HIV-1 vaccine based on bacterium-like particles elicits Env-specific mucosal immune responses.
-
An Hfe-dependent pathway mediates hyposideremia in response to lipopolysaccharide-induced inflammation in mice.
-
An Immunogenic and Slow-Growing Cryptococcal Strain Induces a Chronic Granulomatous Infection in Murine Lungs.
-
An Improved 211At-Labeled Agent for PSMA-Targeted α-Therapy.
-
An In Vivo Definition of Brain Histamine Dynamics Reveals Critical Neuromodulatory Roles for This Elusive Messenger.
-
An In Vivo Model of Echovirus-Induced Meningitis Defines the Differential Roles of Type I and Type III Interferon Signaling in Central Nervous System Infection.
-
An In Vivo Screen Identifies PYGO2 as a Driver for Metastatic Prostate Cancer.
-
An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma.
-
An L-selectin ligand distinct from P-selectin glycoprotein ligand-1 is expressed on endothelial cells and promotes neutrophil rolling in inflammation.
-
An N-ethyl-N-nitrosourea mutagenesis recessive screen identifies two candidate regions for murine cardiomyopathy that map to chromosomes 1 and 15.
-
An NLRP3 Mutation Causes Arthropathy and Osteoporosis in Humanized Mice.
-
An SSLP marker-anchored BAC framework map of the mouse genome.
-
An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer.
-
An accumulation of non-farnesylated prelamin A causes cardiomyopathy but not progeria.
-
An acquired channelopathy involving thalamic T-type Ca2+ channels after status epilepticus.
-
An activated factor VII variant with enhanced tissue factor-independent activity speeds wound healing in a mouse hemophilia B model.
-
An adenoviral vaccine encoding full-length inactivated human Her2 exhibits potent immunogenicty and enhanced therapeutic efficacy without oncogenicity.
-
An alanine residue in the M3-M4 linker lines the glycine binding pocket of the N-methyl-D-aspartate receptor.
-
An alternative and effective HIV vaccination approach based on inhibition of antigen presentation attenuators in dendritic cells.
-
An alternative splice form of Mdm2 induces p53-independent cell growth and tumorigenesis.
-
An analysis of T cell intrinsic roles of E2A by conditional gene disruption in the thymus.
-
An analysis of the uncertainty and bias in DCE-MRI measurements using the spoiled gradient-recalled echo pulse sequence.
-
An animal model of MYC-driven medulloblastoma.
-
An anionic, endosome-escaping polymer to potentiate intracellular delivery of cationic peptides, biomacromolecules, and nanoparticles.
-
An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan.
-
An anti-inflammatory role for carbon monoxide and heme oxygenase-1 in chronic Th2-mediated murine colitis.
-
An anti-silencer- and SATB1-dependent chromatin hub regulates Rag1 and Rag2 gene expression during thymocyte development.
-
An antibody from single human VH-rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion.
-
An anxiety-like phenotype in mice selectively bred for aggression.
-
An apoE-derived mimic peptide, COG1410, alleviates early brain injury via reducing apoptosis and neuroinflammation in a mouse model of subarachnoid hemorrhage.
-
An apolipoprotein E-based therapeutic improves outcome and reduces Alzheimer's disease pathology following closed head injury: evidence of pharmacogenomic interaction.
-
An apolipoprotein E-mimetic stimulates axonal regeneration and remyelination after peripheral nerve injury.
-
An array of 60,000 antibodies for proteome-scale antibody generation and target discovery.
-
An artery-specific fluorescent dye for studying neurovascular coupling.
-
An assessment of the effects of shell cross-linked nanoparticle size, core composition, and surface PEGylation on in vivo biodistribution.
-
An automated decision-tree approach to predicting protein interaction hot spots.
-
An ear punch model for studying the effect of radiation on wound healing.
-
An effective AIDS vaccine based on live attenuated vesicular stomatitis virus recombinants.
-
An efficient multiple-exposure analysis of the toxicity of crisnatol, a DNA intercalator in phase II clinical trials.
-
An encyclopedia of mouse DNA elements (Mouse ENCODE).
-
An endogenous TNF-alpha antagonist induced by splice-switching oligonucleotides reduces inflammation in hepatitis and arthritis mouse models.
-
An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a.
-
An engineered vascular endothelial growth factor-activating transcription factor induces therapeutic angiogenesis in ApoE knockout mice with hindlimb ischemia.
-
An enhancer-based gene-therapy strategy for spatiotemporal control of cargoes during tissue repair.
-
An enteroendocrine cell-enteric glia connection revealed by 3D electron microscopy.
-
An entirely cell-based system to generate single-chain antibodies against cell surface receptors.
-
An essential function for the calcium-promoted Ras inactivator in Fcgamma receptor-mediated phagocytosis.
-
An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype.
-
An essential role for RasGRP1 in mast cell function and IgE-mediated allergic response.
-
An essential role for an inositol polyphosphate multikinase, Ipk2, in mouse embryogenesis and second messenger production.
-
An essential role for c-FLIP in the efficient development of mature T lymphocytes.
-
An essential role for mitochondrial aldehyde dehydrogenase in nitroglycerin bioactivation.
-
An essential role for the Glut1 PDZ-binding motif in growth factor regulation of Glut1 degradation and trafficking.
-
An essential role of Bmp4 in the atrioventricular septation of the mouse heart.
-
An essential role of antibodies in the control of Chikungunya virus infection.
-
An evolved AAV variant enables efficient genetic engineering of murine T cells.
-
An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.
-
An imaging-based approach to identify ligands for olfactory receptors.
-
An important role of phospholipase Cgamma1 in pre-B-cell development and allelic exclusion.
-
An in vitro assay procedure to test chemotherapeutic drugs on cells from human solid tumors.
-
An in vivo model to quantify motor and sensory peripheral nerve regeneration using bioresorbable nerve guide tubes.
-
An in vivo platform for translational drug development in pancreatic cancer.
-
An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1.
-
An increase in the myocardial PCr/ATP ratio in GLUT4 null mice.
-
An inhibitor of macrophage chemotaxis produced by neoplasms.
-
An inhibitor of nuclear scaffold protease blocks chemical transformation of fibroblasts.
-
An injectable method for noninvasive spine fusion.
-
An integrated widefield imaging and spectroscopy system for contrast-enhanced, image-guided resection of tumors.
-
An integrative model of mouse cardiac electrophysiology from cell to torso.
-
An interdomain interaction of the androgen receptor is required for its aggregation and toxicity in spinal and bulbar muscular atrophy.
-
An internalization signal in the simian immunodeficiency virus transmembrane protein cytoplasmic domain modulates expression of envelope glycoproteins on the cell surface.
-
An intracellular role for ABCG1-mediated cholesterol transport in the regulated secretory pathway of mouse pancreatic beta cells.
-
An intravital window to image the colon in real time.
-
An intrinsic oscillator drives the blood stage cycle of the malaria parasite Plasmodium falciparum.
-
An intron facilitates activation of the calspermin gene by the testis-specific transcription factor CREM tau.
-
An investigation of hemopexin redox properties by spectroelectrochemistry: biological relevance for heme uptake.
-
An investigation of kV mini-GRID spatially fractionated radiation therapy: dosimetry and preclinical trial.
-
An olfactory sensory map develops in the absence of normal projection neurons or GABAergic interneurons.
-
An oncogenic Ezh2 mutation induces tumors through global redistribution of histone 3 lysine 27 trimethylation.
-
An opposite role for tau in circadian rhythms revealed by mathematical modeling.
-
An overview of lung cancer genomics and proteomics.
-
An oxidized extracellular oxidation-reduction state increases Nox1 expression and proliferation in vascular smooth muscle cells via epidermal growth factor receptor activation.
-
An ultra-sensitive method to detect mutations in human RAS templates.
-
An ultrastructural study of C-type virion assembly in mouse cells.
-
An unbiased in vivo functional genomics screening approach in mice identifies novel tumor cell-based regulators of immune rejection.
-
Anabolic effects of a G protein-coupled receptor kinase inhibitor expressed in osteoblasts.
-
Anabolic function of the type II isozyme of hexokinase in hepatic lipid synthesis.
-
Anabolism-Associated Mitochondrial Stasis Driving Lymphocyte Differentiation over Self-Renewal.
-
Analyses of Calcium-Independent Phospholipase A2beta (iPLA2β) in Biological Systems.
-
Analysis of ALDH1A2, CYP26A1, CYP26B1, CRABP1, and CRABP2 in human neural tube defects suggests a possible association with alleles in ALDH1A2.
-
Analysis of Brain Protein Stability Changes in Mouse Models of Normal Aging and α-Synucleinopathy Reveals Age- and Disease-Related Differences.
-
Analysis of DNA damage and repair in nuclear and mitochondrial DNA of animal cells using quantitative PCR.
-
Analysis of HIF-1 inhibition by manassantin A and analogues with modified tetrahydrofuran configurations.
-
Analysis of T-cell differentiation antigens in acute lymphatic leukemia using monoclonal antibodies.
-
Analysis of TRPV channel activation by stimulation of FCεRI and MRGPR receptors in mouse peritoneal mast cells.
-
Analysis of a food-borne fungal pathogen outbreak: virulence and genome of a Mucor circinelloides isolate from yogurt.
-
Analysis of corneal and conjunctival microenvironments using monoclonal antibodies.
-
Analysis of expression of multiple genes encoding calmodulin during spermatogenesis.
-
Analysis of gene mutations and clastogenicity following short-term treatment with azathioprine in MutaMouse.
-
Analysis of left ventricular hemodynamics in physiological hyperspace.
-
Analysis of long range correlations due to coherent light scattering from in-vitro cell arrays using angle-resolved low coherence interferometry.
-
Analysis of mRNA partitioning between the cytosol and endoplasmic reticulum compartments of mammalian cells.
-
Analysis of messenger ribonucleic acid and protein for the ligands and receptors of the platelet-derived growth factor signaling pathway in the placenta, extraembryonic membranes, and uterus during the latter half of murine gestation.
-
Analysis of multi-arm tumor growth trials in xenograft animals using phase change adaptive piecewise quadratic models.
-
Analysis of muscle creatine kinase regulatory elements in recombinant adenoviral vectors.
-
Analysis of neurogenesis in a mammalian neuroepithelium: proliferation and differentiation of an olfactory neuron precursor in vitro.
-
Analysis of neuronal proliferation, migration and differentiation in the postnatal brain using equine infectious anemia virus-based lentiviral vectors.
-
Analysis of oxygen/glucose-deprivation-induced changes in SUMO3 conjugation using SILAC-based quantitative proteomics.
-
Analysis of recombinant Phex: an endopeptidase in search of a substrate.
-
Analysis of regulatory CD8 T cells in Qa-1-deficient mice.
-
Analysis of repetitive sequence elements containing tRNA-like sequences.
-
Analysis of the Conditions That Affect the Selective Processing of Endogenous Notch1 by ADAM10 and ADAM17.
-
Analysis of the E399D mutation in SLC11A2.
-
Analysis of the Rab GTPase Interactome in Dendritic Cells Reveals Anti-microbial Functions of the Rab32 Complex in Bacterial Containment.
-
Analysis of the biologic properties of p230 Bcr-Abl reveals unique and overlapping properties with the oncogenic p185 and p210 Bcr-Abl tyrosine kinases.
-
Analysis of the globose basal cell compartment in rat olfactory epithelium using GBC-1, a new monoclonal antibody against globose basal cells.
-
Analysis of the linker for activation of T cells and the linker for activation of B cells in natural killer cells reveals a novel signaling cassette, dual usage in ITAM signaling, and influence on development of the Ly49 repertoire.
-
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
-
Analysis of the mouse transcriptome for genes involved in the function of the nervous system.
-
Analysis of the relationship between stage of differentiation and NK/LAK susceptibility of colon carcinoma cells.
-
Analysis of the role of E2A-encoded proteins in insulin gene transcription.
-
Analysis of the role of membrane polarity in polycystic kidney disease of transgenic SBM mice.
-
Analysis of transcriptome complexity through RNA sequencing in normal and failing murine hearts.
-
Analyzing somatosensory axon projections with the sensory neuron-specific Advillin gene.
-
Anaplastic human gliomas grown in athymic mice. Morphology and glial fibrillary acidic protein expression.
-
Anatomical and functional imaging of myocardial infarction in mice using micro-CT and eXIA 160 contrast agent.
-
Anatomy and spatial organization of Müller glia in mouse retina.
-
Ancestral and consensus envelope immunogens for HIV-1 subtype C.
-
Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells
-
Anchorage-independent cell growth signature identifies tumors with metastatic potential.
-
Androgen decreases dopamine neurone survival in rat midbrain.
-
Androgen receptor down-regulation in prostate cancer with phosphorodiamidate morpholino antisense oligomers.
-
Androgen receptor splice variant AR3 promotes prostate cancer via modulating expression of autocrine/paracrine factors.
-
Androgen receptor with short polyglutamine tract preferably enhances Wnt/β-catenin-mediated prostatic tumorigenesis.
-
Androgen-independent prostate cancer progression in the TRAMP model.
-
Androgen-mediated immune function is altered by the apolipoprotein E gene.
-
Androgenic dependence of exophytic tumor growth in a transgenic mouse model of bladder cancer: a role for thrombospondin-1.
-
Anemia of inflammation: the cytokine-hepcidin link.
-
Angiogenesis and growth of isografted bone: quantitative in vivo assay in nude mice.
-
Angiogenesis, microvascular architecture, microhemodynamics, and interstitial fluid pressure during early growth of human adenocarcinoma LS174T in SCID mice.
-
Angiogenic growth factors in the pathophysiology of a murine model of acute lung injury.
-
Angiopoietin receptor TEK mutations underlie primary congenital glaucoma with variable expressivity.
-
Angiopoietin-1 is required for Schlemm's canal development in mice and humans.
-
Angiopoietin-2 confers Atheroprotection in apoE-/- mice by inhibiting LDL oxidation via nitric oxide.
-
Angiostatin-like activity of a monoclonal antibody to the catalytic subunit of F1F0 ATP synthase.
-
Angiotensin 1-7 reduces mortality and rupture of intracranial aneurysms in mice.
-
Angiotensin AT1B receptor mediates calcium signaling in vascular smooth muscle cells of AT1A receptor-deficient mice.
-
Angiotensin II Short-Loop Feedback: Is There a Role of Ang II for the Regulation of the Renin System In Vivo?
-
Angiotensin II Type 1A Receptor Expressed in Smooth Muscle Cells is Required for Hypertensive Vascular Remodeling in Mice Infused With Angiotensin II.
-
Angiotensin II acts through the angiotensin 1a receptor to upregulate pendrin.
-
Angiotensin II attenuates chemical hypoxia-induced caspase-3 activation in primary cortical neuronal cultures.
-
Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney.
-
Angiotensin II enhances bacterial clearance via myeloid signaling in a murine sepsis model.
-
Angiotensin II plays a role in acute murine experimental autoimmune cystitis.
-
Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E-deficient mice.
-
Angiotensin II promotes development of the renal microcirculation through AT1 receptors.
-
Angiotensin II regulates cellular immune responses through a calcineurin-dependent pathway.
-
Angiotensin II responses in AT1A receptor-deficient mice: a role for AT1B receptors in blood pressure regulation.
-
Angiotensin II stimulates canonical TGF-β signaling pathway through angiotensin type 1 receptor to induce granulation tissue contraction.
-
Angiotensin II synergizes with BAFF to promote atheroprotective regulatory B cells.
-
Angiotensin II type 1 receptor-associated protein is an endogenous inhibitor of angiotensin II type 1 receptor action in cardiac hypertrophy: role in check and balance.
-
Angiotensin II type 1A receptors in vascular smooth muscle cells do not influence aortic remodeling in hypertension.
-
Angiotensin II type 2 receptor mediates programmed cell death.
-
Angiotensin II-induced MMP-2 activity and MMP-14 and basigin protein expression are mediated via the angiotensin II receptor type 1-mitogen-activated protein kinase 1 pathway in retinal pigment epithelium: implications for age-related macular degeneration.
-
Angiotensin II-induced hypertension regulates AT1 receptor subtypes and extracellular matrix turnover in mouse retinal pigment epithelium.
-
Angiotensin II: an immune costimulator?
-
Angiotensin converting enzyme and genetic hypertension: cloning of rat cDNAs and characterization of the enzyme.
-
Angiotensin induces the urinary peristaltic machinery during the perinatal period.
-
Angiotensin protects cortical neurons from hypoxic-induced apoptosis via the angiotensin type 2 receptor.
-
Angiotensin receptor signaling and prostate tumor growth in mice.
-
Angiotensin receptors in the kidney and vasculature in hypertension and kidney disease.
-
Angiotensin type 2 receptor is expressed in murine atherosclerotic lesions and modulates lesion evolution.
-
Angiotensin-(1-7) Attenuates Skeletal Muscle Fibrosis and Stiffening in a Mouse Model of Extremity Sarcoma Radiation Therapy.
-
Angiotensin-converting enzyme 2 gene targeting studies in mice: mixed messages.
-
Angiotensinogen gene null-mutant mice lack homeostatic regulation of glomerular filtration and tubular reabsorption.
-
Animal Models and Their Role in Imaging-Assisted Co-Clinical Trials.
-
Animal model for maturity-onset diabetes of the young generated by disruption of the mouse glucokinase gene.
-
Animal models in the research of abdominal aortic aneurysms development.
-
Animal models of bleeding and tissue repair.
-
Animal models of hereditary iron transport disorders.
-
Animal models of human prostate cancer: the consensus report of the New York meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee.
-
Animal models of steatohepatitis.
-
Animal models of steatosis.
-
Animal models provide insight into psychosomatic factors in diabetes.
-
Animals lacking endothelin-converting enzyme-2 are deficient in learning and memory.
-
Ank3-dependent SVZ niche assembly is required for the continued production of new neurons.
-
Ankrd11 is a chromatin regulator involved in autism that is essential for neural development.
-
Ankyrin-B coordinates the Na/K ATPase, Na/Ca exchanger, and InsP3 receptor in a cardiac T-tubule/SR microdomain.
-
Ankyrin-B directs membrane tethering of periaxin and is required for maintenance of lens fiber cell hexagonal shape and mechanics.
-
Ankyrin-B interactions with spectrin and dynactin-4 are required for dystrophin-based protection of skeletal muscle from exercise injury.
-
Ankyrin-B is a PI3P effector that promotes polarized α5β1-integrin recycling via recruiting RabGAP1L to early endosomes.
-
Ankyrin-B is required for coordinated expression of beta-2-spectrin, the Na/K-ATPase and the Na/Ca exchanger in the inner segment of rod photoreceptors.
-
Ankyrin-B is required for intracellular sorting of structurally diverse Ca2+ homeostasis proteins.
-
Ankyrin-B metabolic syndrome combines age-dependent adiposity with pancreatic β cell insufficiency.
-
Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death.
-
Ankyrin-B syndrome: enhanced cardiac function balanced by risk of cardiac death and premature senescence.
-
Ankyrin-B targets beta2-spectrin to an intracellular compartment in neonatal cardiomyocytes.
-
Ankyrin-G Inhibits Endocytosis of Cadherin Dimers.
-
Ankyrin-G and beta2-spectrin collaborate in biogenesis of lateral membrane of human bronchial epithelial cells.
-
Ankyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segments.
-
Ankyrin-G coordinates intercalated disc signaling platform to regulate cardiac excitability in vivo.
-
Ankyrin-G is a molecular partner of E-cadherin in epithelial cells and early embryos.
-
Ankyrin-G promotes cyclic nucleotide-gated channel transport to rod photoreceptor sensory cilia.
-
Ankyrin-G regulates forebrain connectivity and network synchronization via interaction with GABARAP.
-
Ankyrin-based subcellular gradient of neurofascin, an immunoglobulin family protein, directs GABAergic innervation at purkinje axon initial segment.
-
Ankyrin-rich membrane spanning protein as a novel modulator of transient receptor potential vanilloid 1-function in nociceptive neurons.
-
AnkyrinG is required for clustering of voltage-gated Na channels at axon initial segments and for normal action potential firing.
-
AnkyrinG is required to maintain axo-dendritic polarity in vivo.
-
Ankyrins.
-
Annexin-A1 Tripeptide Attenuates Surgery-Induced Neuroinflammation and Memory Deficits Through Regulation the NLRP3 Inflammasome.
-
Another cystic mystery solved.
-
Anovulation in cyclooxygenase-2-deficient mice is restored by prostaglandin E2 and interleukin-1beta.
-
Antagonism Between PEDF and TGF-β Contributes to Type VI Osteogenesis Imperfecta Bone and Vascular Pathogenesis.
-
Antagonism of AT2 receptors augments angiotensin II-induced abdominal aortic aneurysms and atherosclerosis.
-
Antagonists of the system L neutral amino acid transporter (LAT) promote endothelial adhesivity of human red blood cells.
-
Anterior pituitary hypoplasia and dwarfism in mice lacking the dopamine transporter.
-
Anti-AIDS agents. 34. Synthesis and structure-activity relationships of betulin derivatives as anti-HIV agents.
-
Anti-CD22 ligand-blocking antibody HB22.7 has independent lymphomacidal properties and augments the efficacy of 90Y-DOTA-peptide-Lym-1 in lymphoma xenografts.
-
Anti-CD37 chimeric antigen receptor T cells are active against B- and T-cell lymphomas.
-
Anti-CD40 ligand monoclonal antibody delays the progression of murine autoimmune cholangitis.
-
Anti-DNA and autoantibodies.
-
Anti-DNA antibodies form immune deposits at distinct glomerular and vascular sites.
-
Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation.
-
Anti-EGFRvIII monoclonal antibody armed with 177Lu: in vivo comparison of macrocyclic and acyclic ligands.
-
Anti-Ebola MAb 17A3 reacts with bovine and human alpha-2-macroglobulin proteins.
-
Anti-La antibody production by MRL-1pr/1pr mice. Analysis of fine specificity.
-
Anti-PD-1 treatment impairs opioid antinociception in rodents and nonhuman primates.
-
Anti-PEG Antibodies Inhibit the Anticoagulant Activity of PEGylated Aptamers.
-
Anti-Sm autoantibodies in MRL mice: analysis of precursor frequency.
-
Anti-U1A monoclonal antibodies recognize unique epitope targets of U1A which are involved in the binding of U1 RNA.
-
Anti-VEGF treatment-resistant pancreatic cancers secrete proinflammatory factors that contribute to malignant progression by inducing an EMT cell phenotype.
-
Anti-adhesive bioresorbable elastomer-coated composite hernia mesh that reduce intraperitoneal adhesions.
-
Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration.
-
Anti-amyloid-beta immunotherapy in Alzheimer's disease: relevance of transgenic mouse studies to clinical trials.
-
Anti-angiogenesis effect of the novel anti-inflammatory and pro-resolving lipid mediators.
-
Anti-angiogenic effects of interleukin-12 delivered by a novel hyperthermia induced gene construct.
-
Anti-angiogenic pigment epithelium-derived factor regulates hepatocyte triglyceride content through adipose triglyceride lipase (ATGL).
-
Anti-bombesin monoclonal antibodies modulate fetal mouse lung growth and maturation in utero and in organ cultures.
-
Anti-fibrotic activity of a rho-kinase inhibitor restores outflow function and intraocular pressure homeostasis.
-
Anti-glycoprotein D monoclonal antibody protects against herpes simplex virus type 1-induced diseases in mice functionally depleted of selected T-cell subsets or asialo GM1+ cells.
-
Anti-idiotypic antibodies as vaccine candidates. The immune network.
-
Anti-idiotypic monoclonal Ig specific for an anti-laminin Ig heavy chain transgene variable region.
-
Anti-idiotypic monoclonal antibodies to GM1 identify ganglioside binding proteins.
-
Anti-inflammatory activity of amine cyanoboranes, amine carboxyboranes, and related compounds.
-
Anti-inflammatory and Anti-HIV Compounds from Swertia bimaculata.
-
Anti-inflammatory and anti-osteoporotic activities of base-boronated nucleosides and phosphate-boronated nucleotides in rodents.
-
Anti-inflammatory and vasoprotective activity of a retroviral-derived peptide, homologous to human endogenous retroviruses: endothelial cell effects.
-
Anti-inflammatory effects of inhibiting the amine oxidase activity of semicarbazide-sensitive amine oxidase.
-
Anti-inflammatory effects of progesterone in lipopolysaccharide-stimulated BV-2 microglia.
-
Anti-intercellular adhesion molecule-1 antibody and intercellular adhesion molecule-1 gene deficiency do not prevent pulmonary neutrophil recruitment in polymicrobial sepsis.
-
Anti-laminin reactivity and glomerular immune deposition by in vitro recombinant antibodies.
-
Anti-mouse mesangial cell serum induces acute glomerulonephropathy in mice.
-
Anti-receptor antibody-induced H-Y-specific delayed-type hypersensitivity responses in nonresponder mice.
-
Anti-receptor antibody-induced suppression of murine H-Y-specific delayed-type hypersensitivity responses.
-
Anti-tubulin drugs conjugated to anti-ErbB antibodies selectively radiosensitize.
-
Anti-tumor activity of a novel monoclonal antibody, NPC-1C, optimized for recognition of tumor antigen MUC5AC variant in preclinical models.
-
Anti-tumor immunotherapy despite immunity to adenovirus using a novel adenoviral vector Ad5 [E1-, E2b-]-CEA.
-
Antiadhesive properties of a quaternary structure-specific hybridoma antibody against type 1 fimbriae of Escherichia coli.
-
Antiangiogenic action of redox-modulating Mn(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin, MnTE-2-PyP(5+), via suppression of oxidative stress in a mouse model of breast tumor.
-
Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2.
-
Antiangiogenic treatment with the three thrombospondin-1 type 1 repeats recombinant protein in an orthotopic human pancreatic cancer model.
-
Antiangiogenic treatment with three thrombospondin-1 type 1 repeats versus gemcitabine in an orthotopic human pancreatic cancer model.
-
Antiapoptotic Bcl-2 family proteins BCL-xL and MCL-1 integrate neural progenitor survival and proliferation during postnatal cerebellar neurogenesis.
-
Antibiotic-induced changes in the microbiota disrupt redox dynamics in the gut.
-
Antibodies against trimeric S glycoprotein protect hamsters against SARS-CoV challenge despite their capacity to mediate FcgammaRII-dependent entry into B cells in vitro.
-
Antibodies as specific renin inhibitors: studies with polyclonal and monoclonal antibodies and Fab fragments.
-
Antibodies to a Conserved Influenza Head Interface Epitope Protect by an IgG Subtype-Dependent Mechanism.
-
Antibodies to stem cell marker antigens reduce engraftment of hematopoietic stem cells.
-
Antibody Feedback Limits the Expansion of B Cell Responses to Malaria Vaccination but Drives Diversification of the Humoral Response.
-
Antibody alone does not prevent experimental cytomegalovirus retinitis in mice with retrovirus-induced immunodeficiency (MAIDS).
-
Antibody binding to a conformation-dependent epitope induces L-selectin association with the detergent-resistant cytoskeleton.
-
Antibody formation and mannose-6-phosphate receptor expression impact the efficacy of muscle-specific transgene expression in murine Pompe disease.
-
Antibody is critical for the clearance of murine norovirus infection.
-
Antibody isotype-specific engagement of Fcgamma receptors regulates B lymphocyte depletion during CD20 immunotherapy.
-
Antibody reacting with mouse mammary tumor virus in serum of breast carcinoma patients.
-
Antibody response to a T-dependent antigen requires B cell expression of complement receptors.
-
Antibody-Armed Platelets for the Regenerative Targeting of Endogenous Stem Cells.
-
Antibody-dependent cytolysis (ADCC) of tumor cells by activated murine macrophages is a two-step process: quantification of target binding and subsequent target lysis.
-
Antibody-induced proteinase activation: a proposed mechanism for pemphigus.
-
Antibody-mediated B-cell depletion before adoptive immunotherapy with T cells expressing CD20-specific chimeric T-cell receptors facilitates eradication of leukemia in immunocompetent mice.
-
Antibody-mediated enhancement aggravates chikungunya virus infection and disease severity.
-
Antibody-mediated enzyme replacement therapy targeting both lysosomal and cytoplasmic glycogen in Pompe disease.
-
Antibody-targeted photodynamic therapy.
-
Anticancer therapeutic potential of Mn porphyrin/ascorbate system.
-
Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor.
-
Antidepressant actions of histone deacetylase inhibitors.
-
Antidote-mediated control of an anticoagulant aptamer in vivo.
-
Antiepidermal growth factor variant III scFv fragment: effect of radioiodination method on tumor targeting and normal tissue clearance.
-
Antigen delivery by alpha(2)-macroglobulin enhances the cytotoxic T lymphocyte response.
-
Antigen drives very low affinity B cells to become plasmacytes and enter germinal centers.
-
Antigen receptor repertoire profiling from RNA-seq data.
-
Antigen-binding repertoire and Ig H chain gene usage among B cell hybridomas from normal and autoimmune mice.
-
Antigen-loaded monocyte administration induces potent therapeutic antitumor T cell responses.
-
Antigen-presenting cells pulsed with unfractionated tumor-derived peptides are potent tumor vaccines.
-
Antigen-specific induced Foxp3+ regulatory T cells are generated following CD40/CD154 blockade.
-
Antigenicity and immunogenicity of a synthetic human immunodeficiency virus type 1 group m consensus envelope glycoprotein.
-
Antigens of human pancreatic adenocarcinoma cells defined by murine monoclonal antibodies.
-
Antigens shared by rat schwannomas, neuroblastomas, and a testicular interstitial cell carcinoma.
-
Antihelminth compound niclosamide downregulates Wnt signaling and elicits antitumor responses in tumors with activating APC mutations.
-
Antihyperlipidemic activity of amine cyanoboranes, amine carboxyboranes, and related compounds.
-
Antiidiotypic antibody recognizes an amiloride binding domain within the alpha subunit of the epithelial Na+ channel.
-
Antiinflammatory proteins associated with human and murine neoplasms.
-
Antillatoxin, a novel lipopeptide, enhances neurite outgrowth in immature cerebrocortical neurons through activation of voltage-gated sodium channels.
-
Antineoplastic activity of a series of boron analogues of alpha-amino acids.
-
Antineoplastic activity of boron-containing thymidine nucleosides in Tmolt3 leukemic cells.
-
Antineoplastic activity of tetrakis-mu-(trimethylamine-boranecarboxylato)-bis (trimethylamine-carboxyborane)dicopper (II) in Ehrlich ascites carcinoma.
-
Antinuclear antibodies and nuclear antigens in NZB myeloma ascitic fluids.
-
Antioxidants preserve macrophage phagocytosis of Pseudomonas aeruginosa during hyperoxia.
-
Antioxidants suppress mortality in the female NZB x NZW F1 mouse model of systemic lupus erythematosus (SLE).
-
Antiproliferative effects of cyclocreatine on human prostatic carcinoma cells.
-
Antiproliferative effects of interferon alpha on hepatic progenitor cells in vitro and in vivo.
-
Antiseizure effects of TrkB kinase inhibition.
-
Antisense inhibition of P-glycoprotein expression using peptide-oligonucleotide conjugates.
-
Antisense inhibition of group II phospholipase A2 expression blocks the production of prostaglandin E2 by P388D1 cells.
-
Antisense oligonucleotides targeting mutant Ataxin-7 restore visual function in a mouse model of spinocerebellar ataxia type 7.
-
Antitenascin antibody 81C6 armed with 177Lu: in vivo comparison of macrocyclic and acyclic ligands.
-
Antitumor Activity of a Mitochondrial-Targeted HSP90 Inhibitor in Gliomas.
-
Antitumor activity of a monoclonal antibody directed against gastrin-releasing peptide in patients with small cell lung cancer.
-
Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models.
-
Antitumor and Antiangiogenic Effects of Aspirin-PC in Ovarian Cancer.
-
Antitumorigenesis of antioxidants in a transgenic Rac1 model of Kaposi's sarcoma.
-
Antitumour activity of S-p-bromobenzylglutathione cyclopentyl diester in vitro and in vivo. Inhibition of glyoxalase I and induction of apoptosis.
-
Antiviral Effects of ABMA against Herpes Simplex Virus Type 2 In Vitro and In Vivo.
-
Antiviral activity of human OASL protein is mediated by enhancing signaling of the RIG-I RNA sensor.
-
Antiviral activity of mixed-valence rare earth borotungstate heteropoly blues against influenza virus in mice.
-
Anxiety-like behaviors in mice lacking GIT2.
-
Anxiolytic effects of acute morphine can be modulated by nitric oxide systems.
-
Apical CLC-2 in retinal pigment epithelium is crucial for survival of the outer retina.
-
Apo E structure determines VLDL clearance and atherosclerosis risk in mice.
-
ApoB-48 and apoB-100 differentially influence the expression of type-III hyperlipoproteinemia in APOE*2 mice.
-
ApoE isoform affects LTP in human targeted replacement mice.
-
ApoE isoform-specific effects on LTP: blockade by oligomeric amyloid-beta1-42.
-
ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy.
-
ApoER2 function in the establishment and maintenance of retinal synaptic connectivity.
-
ApoJ/Clusterin concentrations are determinants of cerebrospinal fluid cholesterol efflux capacity and reduced levels are associated with Alzheimer's disease.
-
Apolipoprotein E COG 133 mimetic peptide improves 5-fluorouracil-induced intestinal mucositis.
-
Apolipoprotein E Exerts a Whole-Brain Protective Property by Promoting M1? Microglia Quiescence After Experimental Subarachnoid Hemorrhage in Mice.
-
Apolipoprotein E Mimetic Peptide Increases Cerebral Glucose Uptake by Reducing Blood-Brain Barrier Disruption after Controlled Cortical Impact in Mice: An 18F-Fluorodeoxyglucose PET/CT Study.
-
Apolipoprotein E acts to increase nitric oxide production in macrophages by stimulating arginine transport.
-
Apolipoprotein E affects the central nervous system response to injury and the development of cerebral edema.
-
Apolipoprotein E allele-dependent pathogenesis: a model for age-related retinal degeneration.
-
Apolipoprotein E and Reelin ligands modulate tau phosphorylation through an apolipoprotein E receptor/disabled-1/glycogen synthase kinase-3beta cascade.
-
Apolipoprotein E and mimetic peptide initiate a calcium-dependent signaling response in macrophages.
-
Apolipoprotein E and peptide mimetics modulate inflammation by binding the SET protein and activating protein phosphatase 2A.
-
Apolipoprotein E and the CNS response to injury.
-
Apolipoprotein E deficiency worsens outcome from global cerebral ischemia in the mouse.
-
Apolipoprotein E expression and behavioral toxicity of high charge, high energy (HZE) particle radiation.
-
Apolipoprotein E isoform mediated regulation of nitric oxide release.
-
Apolipoprotein E isoform-specific differences in outcome from focal ischemia in transgenic mice.
-
Apolipoprotein E isotype-dependent modulation of microRNA-146a in plasma and brain.
-
Apolipoprotein E knock-out and knock-in mice: atherosclerosis, metabolic syndrome, and beyond.
-
Apolipoprotein E level and cholesterol are associated with reduced synaptic amyloid beta in Alzheimer's disease and apoE TR mouse cortex.
-
Apolipoprotein E modifies the CNS response to injury via a histamine-mediated pathway.
-
Apolipoprotein E modulates glial activation and the endogenous central nervous system inflammatory response.
-
Apolipoprotein E plays a key role against cryptosporidial infection in transgenic undernourished mice.
-
Apolipoprotein E suppresses glial cell secretion of TNF alpha.
-
Apolipoprotein E-Mimetic COG1410 Reduces Acute Vasogenic Edema following Traumatic Brain Injury.
-
Apolipoprotein E-deficient mice created by systemic administration of antisense oligodeoxynucleotides: a new model for lipoprotein metabolism studies.
-
Apolipoprotein E-deficient mice have increased susceptibility to focal cerebral ischemia.
-
Apolipoprotein E-derived peptides ameliorate clinical disability and inflammatory infiltrates into the spinal cord in a murine model of multiple sclerosis.
-
Apolipoprotein E-low density lipoprotein receptor interaction affects spatial memory retention and brain ApoE levels in an isoform-dependent manner.
-
Apolipoprotein E4 Impairs Neuronal Insulin Signaling by Trapping Insulin Receptor in the Endosomes.
-
Apolipoprotein E4 exaggerates diabetic dyslipidemia and atherosclerosis in mice lacking the LDL receptor.
-
Apolipoprotein E4 impairs the response of neurodegenerative retinal microglia and prevents neuronal loss in glaucoma.
-
Apolipoprotein J/clusterin induction in myocarditis: A localized response gene to myocardial injury.
-
ApolipoproteinE mimetic peptides improve outcome after focal ischemia.
-
Apolipoproteins and apolipoprotein mimetic peptides modulate phagocyte trafficking through chemotactic activity.
-
Apoptosis and B cell tolerance.
-
Apoptosis occurs in isolated and banked primary mouse hepatocytes.
-
Apoptosis rate can be accelerated or decelerated by overexpression or reduction of the level of elongation factor-1 alpha.
-
Apoptosis: final common pathway of photoreceptor death in rd, rds, and rhodopsin mutant mice.
-
Apoptotic Debris Accumulates on Hematopoietic Cells and Promotes Disease in Murine and Human Systemic Lupus Erythematosus.
-
Apoptotic cells activate the "phoenix rising" pathway to promote wound healing and tissue regeneration.
-
Apoptotic sensitivity of murine IAP-deficient cells.
-
Apparent elastic modulus and hysteresis of skeletal muscle cells throughout differentiation.
-
Application of a Novel Murine Ear Vein Model to Evaluate the Effects of a Vascular Radioprotectant on Radiation-Induced Vascular Permeability and Leukocyte Adhesion.
-
Application of chemoproteomics to drug discovery: identification of a clinical candidate targeting hsp90.
-
Application of combined omics platforms to accelerate biomedical discovery in diabesity.
-
Application of proteomic marker ensembles to subcellular organelle identification.
-
Approximating transcranial magnetic stimulation with electric stimulation in mouse: a simulation study.
-
Aptamers selected against the unglycosylated EGFRvIII ectodomain and delivered intracellularly reduce membrane-bound EGFRvIII and induce apoptosis.
-
Aquaporin 4 blockade improves survival of murine heart allografts subjected to prolonged cold ischemia.
-
Aquaporin 6 binds calmodulin in a calcium-dependent manner.
-
Aquaporin 9 is the major pathway for glycerol uptake by mouse erythrocytes, with implications for malarial virulence.
-
Aquaporin in Candida: characterization of a functional water channel protein.
-
Arachidonic acid mobilization in P388D1 macrophages is controlled by two distinct Ca(2+)-dependent phospholipase A2 enzymes.
-
Architectural Modification of Conformal PEG-Bottlebrush Coatings Minimizes Anti-PEG Antigenicity While Preserving Stealth Properties.
-
Are there effective new strategies for the treatment of acute and chronic GvHD?
-
Arfgef1 haploinsufficiency in mice alters neuronal endosome composition and decreases membrane surface postsynaptic GABAA receptors.
-
Arginase1 Deficiency in Monocytes/Macrophages Upregulates Inducible Nitric Oxide Synthase To Promote Cutaneous Contact Hypersensitivity.
-
Arginine deprivation and immune suppression in a mouse model of Alzheimer's disease.
-
Argon Inhalation for 24 h After Closed-Head Injury Does not Improve Recovery, Neuroinflammation, or Neurologic Outcome in Mice.
-
Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis.
-
Aromatic hydrocarbon receptor interaction with the retinoblastoma protein potentiates repression of E2F-dependent transcription and cell cycle arrest.
-
Aromatic hydrocarbon receptor polymorphism: development of new methods to correlate genotype with phenotype.
-
Arrestin translocation is induced at a critical threshold of visual signaling and is superstoichiometric to bleached rhodopsin.
-
Arsenic Exposure, Blood DNA Methylation, and Cardiovascular Disease.
-
Arsenic trioxide synergizes with everolimus (Rad001) to induce cytotoxicity of ovarian cancer cells through increased autophagy and apoptosis.
-
Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9.
-
Arterial response to shear stress critically depends on endothelial TRPV4 expression.
-
Arthritis syndromes associated with human T cell lymphotropic virus type I infection.
-
Aryl Hydrocarbon Receptor Signaling Controls CD155 Expression on Macrophages and Mediates Tumor Immunosuppression.
-
Aryl hydrocarbon receptor deficiency causes dysregulated cellular matrix metabolism and age-related macular degeneration-like pathology.
-
Ascites Increases Expression/Function of Multidrug Resistance Proteins in Ovarian Cancer Cells.
-
Aspartyl-(asparaginyl)-beta-hydroxylase regulates hepatocellular carcinoma invasiveness.
-
Aspergillus fumigatus calcipressin CbpA is involved in hyphal growth and calcium homeostasis.
-
Aspirin inhibits tumor necrosis factoralpha gene expression in murine tissue macrophages.
-
Aspirin-triggered resolvin D1 prevents surgery-induced cognitive decline.
-
Assembling OX40 aptamers on a molecular scaffold to create a receptor-activating aptamer.
-
Assembly of signaling complexes by the sodium-hydrogen exchanger regulatory factor family of PDZ-containing proteins.
-
Assembly of the dystrophin-associated protein complex does not require the dystrophin COOH-terminal domain.
-
Assessing a role for enhancer-blocking activity in gene regulation within the murine T-cell receptor alpha/delta locus.
-
Assessing cardiac injury in mice with dual energy-microCT, 4D-microCT, and microSPECT imaging after partial heart irradiation.
-
Assessing overall risk in reproductive experiments.
-
Assessing some dynamic properties of the living nervous system.
-
Assessing the virulence of Cryptococcus neoformans causing meningitis in HIV infected and uninfected patients in Vietnam.
-
Assessment of myeloma maintenance regimen of prednisone. Adriamycin, imuran, and vincristine in a murine plasmacytoma model.
-
Assessment of photosensitizer dosimetry and tissue damage assay for photodynamic therapy in advanced-stage tumors.
-
Assignment of the agent of Tyzzer's disease to Clostridium piliforme comb. nov. on the basis of 16S rRNA sequence analysis.
-
Assignment of the beta-subunit of rod photoreceptor cGMP phosphodiesterase gene PDEB (homolog of the mouse rd gene) to human chromosome 4p16.
-
Assignment of the zeta-crystallin gene (CRYZ) to human chromosome 1p22-p31 and identification of restriction fragment length polymorphisms.
-
Association between the 7 S RNA and the lupus La protein varies among cell types.
-
Association of Variants in BAG3 With Cardiomyopathy Outcomes in African American Individuals.
-
Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks.
-
Association of myosin light chain kinase with lymphocyte membrane-cytoskeleton complex.
-
Association of protein kinase C(lambda) with adducin in 3T3-L1 adipocytes.
-
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease.
-
Association of the adaptor molecule LAT with CD4 and CD8 coreceptors identifies a new coreceptor function in T cell receptor signal transduction.
-
Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.
-
Association of the protein kinases c-Bcr and Bcr-Abl with proteins of the 14-3-3 family.
-
Associations of neighborhood concentrated poverty, neighborhood racial/ethnic composition, and indoor allergen exposures: a cross-sectional analysis of los angeles households, 2006-2008.
-
Astatination of proteins using an N-succinimidyl tri-n-butylstannyl benzoate intermediate.
-
Astatine-211 labeled anti-HER2 5F7 single domain antibody fragment conjugates: radiolabeling and preliminary evaluation.
-
Astatine-211 labeling of internalizing anti-EGFRvIII monoclonal antibody using N-succinimidyl 5-[211At]astato-3-pyridinecarboxylate.
-
Astatine-211-labeled biotin conjugates resistant to biotinidase for use in pretargeted radioimmunotherapy.
-
Astaxanthin but not quercetin preserves mitochondrial integrity and function, ameliorates oxidative stress, and reduces heat-induced skeletal muscle injury.
-
Asteropsin A: an unusual cystine-crosslinked peptide from porifera enhances neuronal Ca2+ influx.
-
Astringency: a more stringent definition.
-
Astrocyte cytolysis by MHC class II-specific mouse T cell clones.
-
Astrocytes Assemble Thalamocortical Synapses by Bridging NRX1α and NL1 via Hevin.
-
Astrocytes follow ganglion cell axons to establish an angiogenic template during retinal development.
-
Astrocytes refine cortical connectivity at dendritic spines.
-
Astrocytic CX43 hemichannels and gap junctions play a crucial role in development of chronic neuropathic pain following spinal cord injury.
-
Astrocytic neuroligins control astrocyte morphogenesis and synaptogenesis.
-
Astroglial toxicity promotes synaptic degeneration in the thalamocortical circuit in frontotemporal dementia with GRN mutations.
-
Asymmetric cell divisions promote stratification and differentiation of mammalian skin.
-
Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation.
-
Ataxia telangiectasia-mutated and p53 are potential mediators of chloroquine-induced resistance to mammary carcinogenesis.
-
Atm deficiency affects both apoptosis and proliferation to augment Myc-induced lymphomagenesis.
-
Atm deletion with dual recombinase technology preferentially radiosensitizes tumor endothelium.
-
Atomic description of the immune complex involved in heparin-induced thrombocytopenia.
-
Atrial chamber-specific expression of sarcolipin is regulated during development and hypertrophic remodeling.
-
Attenuated hepatic inflammation and fibrosis in angiotensin type 1a receptor deficient mice.
-
Attenuated host resistance against Mycobacterium bovis BCG infection in mice lacking osteopontin.
-
Attenuated virulence of a Francisella mutant lacking the lipid A 4'-phosphatase.
-
Attenuation of acid induced oesophagitis in VR-1 deficient mice.
-
Attenuation of cerebral vasospasm after subarachnoid hemorrhage in mice overexpressing extracellular superoxide dismutase.
-
Attenuation of herpes simplex virus neurovirulence with picornavirus cis-acting genetic elements.
-
Attenuation of store-operated Ca2+ current impairs salivary gland fluid secretion in TRPC1(-/-) mice.
-
Attenuation of the effects of punishment by ethanol: comparisons with chlordiazepoxide.
-
Attenuation of the retinoblastoma pathway in pancreatic neuroendocrine tumors due to increased cdk4/cdk6.
-
Attrition of memory CD8 T cells during sepsis requires LFA-1.
-
Atypical antipsychotics rapidly and inappropriately switch peripheral fuel utilization to lipids, impairing metabolic flexibility in rodents.
-
Augmentation of cardiac contractility mediated by the human beta(3)-adrenergic receptor overexpressed in the hearts of transgenic mice.
-
Augmentation of syngeneic tumor-specific immunity by semiallogeneic cell hybrids.
-
Augmentation of transvascular transport of macromolecules and nanoparticles in tumors using vascular endothelial growth factor.
-
Augmented Responses to Ozone in Obese Mice Require IL-17A and Gastrin-Releasing Peptide.
-
Augmenting podocyte injury promotes advanced diabetic kidney disease in Akita mice.
-
Aurora-A kinase is essential for bipolar spindle formation and early development.
-
Aurora-A phosphorylates, activates, and relocalizes the small GTPase RalA.
-
Autism-associated mutation in Hevin/Sparcl1 induces endoplasmic reticulum stress through structural instability.
-
Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice.
-
Autoantibodies against cell surface GRP78 promote tumor growth in a murine model of melanoma.
-
Autoantibodies and their idiotypes.
-
Autocrine BDNF-TrkB signalling within a single dendritic spine.
-
Autocrine Complement Inhibits IL10-Dependent T-cell-Mediated Antitumor Immunity to Promote Tumor Progression.
-
Autocrine inhibition of Na+/K(+)-ATPase by nitric oxide in mouse proximal tubule epithelial cells.
-
Autocrine phosphorylation of p70(S6k) in response to acute stretch in myotubes.
-
Autocrine prolactin induced by the Pten-Akt pathway is required for lactation initiation and provides a direct link between the Akt and Stat5 pathways.
-
Autocrine stimulation of mas oncogene leads to altered growth control.
-
Autofeedback suppression of growth hormone (GH) secretion in transgenic mice expressing a human GH reporter targeted by tyrosine hydroxylase 5'-flanking sequences to the hypothalamus.
-
Autoimmune dacryoadenitis of NOD/LtJ mice and its subsequent effects on tear protein composition.
-
Autoimmunity in dry eye is due to resistance of Th17 to Treg suppression.
-
Autoimmunity: the nuclear arsenal of autoimmunity.
-
Autologous stem cell transplantation for autoimmune diseases: issues in protocol development.
-
Automated Recognition of Retinal Pigment Epithelium Cells on Limited Training Samples Using Neural Networks.
-
Automated design of ligands to polypharmacological profiles.
-
Automated feedback control of body temperature for small animal studies with MR microscopy.
-
Automated radiochemical synthesis and biodistribution of [¹¹C]l-α-acetylmethadol ([¹¹C]LAAM).
-
Automated segmentation of mouse brain images using extended MRF.
-
Automated segmentation of neuroanatomical structures in multispectral MR microscopy of the mouse brain.
-
Automated segmentation of the actively stained mouse brain using multi-spectral MR microscopy.
-
Autophagic activity dictates the cellular response to oncogenic RAS.
-
Autophagy enhances NFκB activity in specific tissue macrophages by sequestering A20 to boost antifungal immunity.
-
Autophagy in the Aging and Experimental Ocular Hypertensive Mouse Model.
-
Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages.
-
Autophagy is essential for mitochondrial clearance in mature T lymphocytes.
-
Autophagy is redundant for the host defense against systemic Candida albicans infections.
-
Autophagy links inflammasomes to atherosclerotic progression.
-
Autophagy provides nutrients but can lead to Chop-dependent induction of Bim to sensitize growth factor-deprived cells to apoptosis.
-
Autophagy regulates T lymphocyte proliferation through selective degradation of the cell-cycle inhibitor CDKN1B/p27Kip1.
-
Autophagy regulates endoplasmic reticulum homeostasis and calcium mobilization in T lymphocytes.
-
Autophagy-dependent metabolic reprogramming sensitizes TSC2-deficient cells to the antimetabolite 6-aminonicotinamide.
-
Autophosphorylation in the leucine-rich repeat kinase 2 (LRRK2) GTPase domain modifies kinase and GTP-binding activities.
-
Autophosphorylation of CaMKK2 generates autonomous activity that is disrupted by a T85S mutation linked to anxiety and bipolar disorder.
-
Autoradiographic analysis of nuclear estrogen binding sites during postnatal development of the genital tract of female mice.
-
Autoreactive B cells recruited to lungs by silica exposure contribute to local autoantibody production in autoimmune-prone BXSB and B cell receptor transgenic mice.
-
Autoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic tolerance.
-
Autoreceptor control of serotonin dynamics.
-
Autoreceptor presynaptic control of dopamine release from striatum is lost at early stages of manganese poisoning.
-
Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene.
-
Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs.
-
Avirulent Toxoplasma gondii generates therapeutic antitumor immunity by reversing immunosuppression in the ovarian cancer microenvironment.
-
Axin gene methylation status correlates with radiosensitivity of lung cancer cells.
-
Axin2 regulates chondrocyte maturation and axial skeletal development.
-
Axonal Odorant Receptors Mediate Axon Targeting.
-
Axonal regrowth after spinal cord injury via chondroitinase and the tissue plasminogen activator (tPA)/plasmin system.
-
Axotomized mouse retinal ganglion cells containing melanopsin show enhanced survival, but not enhanced axon regrowth into a peripheral nerve graft.
-
B Cell Subsets Differentially Contribute to the T Cell-Independent Memory Pool.
-
B Lymphocyte signaling established by the CD19/CD22 loop regulates autoimmunity in the tight-skin mouse.
-
B cell activating factor (BAFF) and a proliferation inducing ligand (APRIL) mediate CD40-independent help by memory CD4 T cells.
-
B cell antigen receptor and CD40 differentially regulate CD22 tyrosine phosphorylation.
-
B cell antigen receptor endocytosis and antigen presentation to T cells require Vav and dynamin.
-
B cell depletion delays collagen-induced arthritis in mice: arthritis induction requires synergy between humoral and cell-mediated immunity.
-
B cell depletion reduces the development of atherosclerosis in mice.
-
B cell maintenance of subcapsular sinus macrophages protects against a fatal viral infection independent of adaptive immunity.
-
B cell-directed therapies for autoimmune disease and correlates of disease response and relapse.
-
B cells are required for optimal CD4+ and CD8+ T cell tumor immunity: therapeutic B cell depletion enhances B16 melanoma growth in mice.
-
B cells contribute to ischemia/reperfusion-mediated tissue injury.
-
B cells in chronic graft-versus-host disease.
-
B cells in chronic graft-versus-host disease.
-
B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies.
-
B lymphocyte depletion by CD20 monoclonal antibody prevents diabetes in nonobese diabetic mice despite isotype-specific differences in Fc gamma R effector functions.
-
B lymphocytes differentially influence acute and chronic allograft rejection in mice.
-
B lymphocytes trigger monocyte mobilization and impair heart function after acute myocardial infarction.
-
B lymphocytes: how they develop and function.
-
B-1a and B-1b cells exhibit distinct developmental requirements and have unique functional roles in innate and adaptive immunity to S. pneumoniae.
-
B-Cell Depletion Reduces the Maturation of Cerebral Cavernous Malformations in Murine Models.
-
B-cell depletion in vitro and in vivo with an afucosylated anti-CD19 antibody.
-
B-cell homeostasis requires complementary CD22 and BLyS/BR3 survival signals.
-
B-cell targeting in chronic graft-versus-host disease.
-
B-lymphocyte contributions to human autoimmune disease.
-
B-lymphocyte depletion ameliorates Sjögren's syndrome in Id3 knockout mice.
-
B-lymphocyte depletion reduces skin fibrosis and autoimmunity in the tight-skin mouse model for systemic sclerosis.
-
B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB.
-
B10 cell regulation of health and disease.
-
B10 cells and regulatory B cells balance immune responses during inflammation, autoimmunity, and cancer.
-
B7-H3-redirected chimeric antigen receptor T cells target glioblastoma and neurospheres.
-
BACPTDP: a water-soluble camptothecin pro-drug with enhanced activity in hypoxic/acidic tumors.
-
BAFF promotes heightened BCR responsiveness and manifestations of chronic GVHD after allogeneic stem cell transplantation.
-
BAG3 (Bcl-2-Associated Athanogene-3) Coding Variant in Mice Determines Susceptibility to Ischemic Limb Muscle Myopathy by Directing Autophagy.
-
BAHCC1 binds H3K27me3 via a conserved BAH module to mediate gene silencing and oncogenesis.
-
BALO: a "mini lung" model to study cell-cell interactions.
-
BAP1 Tumor Predisposition Syndrome Presenting as a Recurrent Ovarian Sex Cord-Stromal Tumor.
-
BAX-mediated cell death affects early germ cell loss and incidence of testicular teratomas in Dnd1(Ter/Ter) mice.
-
BCAA Supplementation in Mice with Diet-induced Obesity Alters the Metabolome Without Impairing Glucose Homeostasis.
-
BCAA catabolism in brown fat controls energy homeostasis through SLC25A44.
-
BCL2 inhibits cell adhesion, spreading, and motility by enhancing actin polymerization.
-
BCL2 interaction with actin in vitro may inhibit cell motility by enhancing actin polymerization.
-
BCR and Endosomal TLR Signals Synergize to Increase AID Expression and Establish Central B Cell Tolerance.
-
BDNF profoundly and specifically increases KCNQ4 expression in neurons derived from embryonic stem cells.
-
BDNF promotes mouse follicular development and reverses ovarian aging by promoting cell proliferation.
-
BDNF regulates the maturation of inhibition and the critical period of plasticity in mouse visual cortex.
-
BDNF-mediated cerebellar granule cell development is impaired in mice null for CaMKK2 or CaMKIV.
-
BEARscc determines robustness of single-cell clusters using simulated technical replicates.
-
BET Bromodomain Inhibitors Which Permit Treg Function Enable a Combinatorial Strategy to Suppress GVHD in Pre-clinical Allogeneic HSCT.
-
BET Inhibitors Suppress ALDH Activity by Targeting ALDH1A1 Super-Enhancer in Ovarian Cancer.
-
BET bromodomain inhibition of MYC-amplified medulloblastoma.
-
BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytes.
-
BLyS and APRIL in rheumatoid arthritis.
-
BMP antagonism by Noggin is required in presumptive notochord cells for mammalian foregut morphogenesis.
-
BMP antagonism is required in both the node and lateral plate mesoderm for mammalian left-right axis establishment.
-
BMP antagonism protects Nodal signaling in the gastrula to promote the tissue interactions underlying mammalian forebrain and craniofacial patterning.
-
BMP ligands act redundantly to pattern the dorsal telencephalic midline.
-
BMP receptor IA is required in mammalian neural crest cells for development of the cardiac outflow tract and ventricular myocardium.
-
BMP receptor IA is required in the mammalian embryo for endodermal morphogenesis and ectodermal patterning.
-
BMP signaling and cellular dynamics during regeneration of airway epithelium from basal progenitors.
-
BMP signaling in the development of the mouse esophagus and forestomach.
-
BMP signaling in the epiblast is required for proper recruitment of the prospective paraxial mesoderm and development of the somites.
-
BMP-2 inhibits tumor growth of human renal cell carcinoma and induces bone formation.
-
BMP-2 inhibits tumor-initiating ability in human renal cancer stem cells and induces bone formation.
-
BMP10 suppresses hepatocellular carcinoma progression via PTPRS-STAT3 axis.
-
BMP2, but not BMP4, is crucial for chondrocyte proliferation and maturation during endochondral bone development.
-
BMP4 is essential for lens induction in the mouse embryo.
-
BRAF Inhibition Stimulates Melanoma-Associated Macrophages to Drive Tumor Growth.
-
BRCA1 is required for common-fragile-site stability via its G2/M checkpoint function.
-
BRCA2 monoclonal antibodies react with differentiating epithelium.
-
BRD4 Prevents R-Loop Formation and Transcription-Replication Conflicts by Ensuring Efficient Transcription Elongation.
-
BRG1 and BRM SWI/SNF ATPases redundantly maintain cardiomyocyte homeostasis by regulating cardiomyocyte mitophagy and mitochondrial dynamics in vivo.
-
BRG1 is a biomarker of hypertrophic cardiomyopathy in human heart specimens.
-
BSTA promotes mTORC2-mediated phosphorylation of Akt1 to suppress expression of FoxC2 and stimulate adipocyte differentiation.
-
BTN3A1 governs antitumor responses by coordinating αβ and γδ T cells.
-
BW2258U89: a GRP receptor antagonist which inhibits small cell lung cancer growth.
-
Bacteria-host cell interaction mediated by cellular cholesterol/glycolipid-enriched microdomains.
-
Bacterial DNA induces murine interferon-gamma production by stimulation of interleukin-12 and tumor necrosis factor-alpha.
-
Bacterial endotoxin stimulates macrophages to release HMGB1 partly through CD14- and TNF-dependent mechanisms.
-
Bacterial infection of osteoblasts induces interleukin-1beta and interleukin-18 transcription but not protein synthesis.
-
Bacterial lipopolysaccharide induces uncoupling protein-2 expression in hepatocytes by a tumor necrosis factor-alpha-dependent mechanism.
-
Bacterial lipopolysaccharides and mycoplasmal lipoglycans: a comparison between their abilities to induce macrophage-mediated tumor cell killing and Limulus amebocyte lysate clotting.
-
Bacterial penetration of bladder epithelium through lipid rafts.
-
Bacterial-mucosal interactions in inflammatory bowel disease: an alliance gone bad.
-
Baculovirus-infected insect cells expressing peptide-MHC complexes elicit protective antitumor immunity.
-
Balance of Irgm protein activities determines IFN-gamma-induced host defense.
-
Balancing the bipotential gonad between alternative organ fates: a new perspective on an old problem.
-
Bartonella henselae: etiology of pulmonary nodules in a patient with depressed cell-mediated immunity.
-
Basal cell adhesion molecule/lutheran protein. The receptor critical for sickle cell adhesion to laminin.
-
Basal cells as stem cells of the mouse trachea and human airway epithelium.
-
Basal epithelial stem cells are efficient targets for prostate cancer initiation.
-
Basal ganglia outputs map instantaneous position coordinates during behavior.
-
Basal laminar deposit formation in APO B100 transgenic mice: complex interactions between dietary fat, blue light, and vitamin E.
-
Base mutations in the terminal noncoding regions of the genome of vesicular stomatitis virus isolated from persistent infections of L cells.
-
Basement membranes.
-
Basic fibroblast growth factor downregulates Bcl-2 and promotes apoptosis in MCF-7 human breast cancer cells.
-
BayFish: Bayesian inference of transcription dynamics from population snapshots of single-molecule RNA FISH in single cells.
-
Bayesian analysis of signaling networks governing embryonic stem cell fate decisions.
-
Bayesian inferences on umbrella orderings.
-
Bayesian latent variable models for mixed discrete outcomes.
-
Bayesian models for multivariate current status data with informative censoring.
-
Bazedoxifene exhibits antiestrogenic activity in animal models of tamoxifen-resistant breast cancer: implications for treatment of advanced disease.
-
Bbeta-adrenergic receptor kinase-1 levels in catecholamine-induced myocardial hypertrophy: regulation by beta- but not alpha1-adrenergic stimulation.
-
Bcl-2 accelerates multistep prostate carcinogenesis in vivo.
-
Bcl-xL is an oncogenic driver in colorectal cancer.
-
Bcr-Abl kinase modulates the translation regulators ribosomal protein S6 and 4E-BP1 in chronic myelogenous leukemia cells via the mammalian target of rapamycin.
-
Bcr-Abl-mediated protection from apoptosis downstream of mitochondrial cytochrome c release.
-
Beat frequency is bimodally distributed in spermatozoa from T/t12 mice.
-
Behavioral and neurochemical changes in folate-deficient mice.
-
Behavioral characterization of P311 knockout mice.
-
Behavioral disturbances in adult mice following neonatal virus infection or kynurenine treatment--role of brain kynurenic acid.
-
Behavioral manipulation of the diabetic phenotype in ob/ob mice.
-
Behavioral phenotyping of transgenic and knockout animals: a cautionary tale.
-
Behavioral responses to social stress in noradrenaline transporter knockout mice: effects on social behavior and depression.
-
Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor in mice.
-
Being there: cellular targeting of voltage-gated sodium channels in the heart.
-
Beneficial effects of cholecystokinin-receptor blockade and inhibition of proteolytic enzyme activity in experimental acute hemorrhagic pancreatitis in mice. Evidence for cholecystokinin as a major factor in the development of acute pancreatitis.
-
Beneficial effects of the Rho kinase inhibitor Y27632 in murine puromycin aminonucleoside nephrosis.
-
Benzyl alcohol protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes but causes mitochondrial dysfunction and cell death at higher doses.
-
Bergmann glia and the recognition molecule CHL1 organize GABAergic axons and direct innervation of Purkinje cell dendrites.
-
Beryllium fluoride-induced cell proliferation: a process requiring P21(ras)-dependent activated signal transduction and NF-kappaB-dependent gene regulation.
-
Bespoke library docking for 5-HT2A receptor agonists with antidepressant activity.
-
Beta-adrenergic axis and heart disease.
-
Beta-adrenergic regulation of cholecystokinin secretion in STC-1 cells.
-
Beta-agonist- and prostaglandin E1-induced translocation of the beta-adrenergic receptor kinase: evidence that the kinase may act on multiple adenylate cyclase-coupled receptors.
-
Beta-arrestin 2 mediates endocytosis of type III TGF-beta receptor and down-regulation of its signaling.
-
Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3.
-
Beta-arrestin and Mdm2 mediate IGF-1 receptor-stimulated ERK activation and cell cycle progression.
-
Beta-arrestin- and G protein receptor kinase-mediated calcium-sensing receptor desensitization.
-
Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7.
-
Beta-arrestin-2 regulates the development of allergic asthma.
-
Beta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection.
-
Beta-arrestin-mediated localization of smoothened to the primary cilium.
-
Beta-arrestin-mediated signaling regulates protein synthesis.
-
Beta-arrestin1 mediates insulin-like growth factor 1 (IGF-1) activation of phosphatidylinositol 3-kinase (PI3K) and anti-apoptosis.
-
Beta-arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes.
-
Beta-arrestins regulate atherosclerosis and neointimal hyperplasia by controlling smooth muscle cell proliferation and migration.
-
Beta-arrestins specifically constrain beta2-adrenergic receptor signaling and function in airway smooth muscle.
-
Beta-blockers alprenolol and carvedilol stimulate beta-arrestin-mediated EGFR transactivation.
-
Beta-caryophyllene enhances wound healing through multiple routes.
-
Beta-catenin and transforming growth factor beta have distinct roles regulating fibroblast cell motility and the induction of collagen lattice contraction.
-
Beta-catenin is a mediator of the response of fibroblasts to irradiation.
-
Beta-catenin regulates wound size and mediates the effect of TGF-beta in cutaneous healing.
-
Beta-catenin signaling pathway is crucial for bone morphogenetic protein 2 to induce new bone formation.
-
Beta-catenin signaling plays a disparate role in different phases of fracture repair: implications for therapy to improve bone healing.
-
Beta1-adrenergic receptors maintain fetal heart rate and survival.
-
Beta1-adrenergic receptors stimulate cardiac contractility and CaMKII activation in vivo and enhance cardiac dysfunction following myocardial infarction.
-
Beta2 adrenergic receptor activation stimulates pro-inflammatory cytokine production in macrophages via PKA- and NF-kappaB-independent mechanisms.
-
Beta2-adrenergic receptor overexpression in the developing mouse heart: evidence for targeted modulation of ion channels.
-
Bevacizumab and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma.
-
Bevacizumab-induced alterations in vascular permeability and drug delivery: a novel approach to augment regional chemotherapy for in-transit melanoma.
-
Bezafibrate induces autophagy and improves hepatic lipid metabolism in glycogen storage disease type Ia.
-
Bi-allelic Variants in TONSL Cause SPONASTRIME Dysplasia and a Spectrum of Skeletal Dysplasia Phenotypes.
-
Bi-ligand surfaces with oriented and patterned protein for real-time tracking of cell migration.
-
Biallelic mutations in FDXR cause neurodegeneration associated with inflammation.
-
Biased Expression of the FOXP3Δ3 Isoform in Aggressive Bladder Cancer Mediates Differentiation and Cisplatin Chemotherapy Resistance.
-
Biased agonists of the chemokine receptor CXCR3 differentially control chemotaxis and inflammation.
-
Biased precursor ingression underlies the center-to-pole pattern of male sex determination in mouse.
-
Bicarbonate alters cellular responses in respiration assays.
-
Bidirectional modulation of substantia nigra activity by motivational state.
-
Bidirectional regulation of postmitotic H3K27me3 distributions underlie cerebellar granule neuron maturation dynamics.
-
Bidirectional signaling links the Abelson kinases to the platelet-derived growth factor receptor.
-
Bifidobacterium animalis subsp. lactis 420 mitigates the pathological impact of myocardial infarction in the mouse.
-
Biliary excretion of glycolipid in induced or inherited glucosylceramide lipidosis.
-
Bimodal quantitative relationships between histone modifications for X-linked and autosomal loci.
-
Binary Fate Choice between Closely Related Interneuronal Types Is Determined by a Fezf1-Dependent Postmitotic Transcriptional Switch.
-
Binding and endocytosis of alpha 2-macroglobulin-plasmin complexes.
-
Binding kinetics of superantigen with TCR and MHC class II.
-
Binding of rat alpha 1-inhibitor-3-methylamine to the alpha 2-macroglobulin signaling receptor induces second messengers.
-
Binding of receptor-recognized forms of alpha2-macroglobulin to the alpha2-macroglobulin signaling receptor activates phosphatidylinositol 3-kinase.
-
Binding of rituximab, trastuzumab, cetuximab, or mAb T101 to cancer cells promotes trogocytosis mediated by THP-1 cells and monocytes.
-
Binding of tenascin-C to soluble fibronectin and matrix fibrils.
-
Binding specificity of a monoclonal anti-DNA antibody.
-
Binocular deprivation induces both age-dependent and age-independent forms of plasticity in parvalbumin inhibitory neuron visual response properties.
-
Bio imaging of intracellular NO production in single bone cells after mechanical stimulation.
-
Bioaccumulation of Novel Per- and Polyfluoroalkyl Substances in Mice Dosed with an Aqueous Film-Forming Foam.
-
Bioactive surface modification of metal oxides via catechol-bearing modular peptides: multivalent-binding, surface retention, and peptide bioactivity.
-
Bioavailability of metalloporphyrin-based SOD mimics is greatly influenced by a single charge residing on a Mn site.
-
Biochemical and biomechanical characteristics of dystrophin-deficient mdx3cv mouse lens.
-
Biochemical and immunological abnormalities in purine nucleoside phosphorylase deficient mice.
-
Biochemical characterization of purified mammalian ARL13B protein indicates that it is an atypical GTPase and ARL3 guanine nucleotide exchange factor (GEF).
-
Biochemical correlates of temozolomide sensitivity in pediatric solid tumor xenograft models.
-
Biochemical identity and characterization of the mouse interleukin-2 receptor beta and gamma c subunits.
-
Biochemical properties of recombinant human and mouse N-acetylglutamate synthase.
-
Biocompatibility studies of functionalized regioregular poly(3-hexylthiophene) layers for sensing applications.
-
Biodistribution of O6-benzylguanine and its effectiveness against human brain tumor xenografts when given in polyethylene glycol or cremophor-EL.
-
Bioelectrorheological model of the cell. 5. Electrodestruction of cellular membrane in alternating electric field.
-
Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells.
-
Bioinformatics Analysis of Gut Microbiota and CNS Transcriptome in Virus-Induced Acute Myelitis and Chronic Inflammatory Demyelination; Potential Association of Distinct Bacteria With CNS IgA Upregulation.
-
Biologic and biochemical activities of continuous macrophage cell lines P388D1 and J774.1.
-
Biological Principles of Stereotactic Body Radiation Therapy (SBRT) and Stereotactic Radiation Surgery (SRS): Indirect Cell Death.
-
Biological Role and Therapeutic Potential of IDH Mutations in Cancer.
-
Biological activity of complement in vivo. Role of C5 in the accumulation of polymorphonuclear leukocytes in inflammatory exudates.
-
Biological age is increased by stress and restored upon recovery.
-
Biological and biochemical consequences of global deletion of exon 3 from the ER alpha gene.
-
Biological basis of germline mutation: comparisons of spontaneous germline mutation rates among drosophila, mouse, and human.
-
Biological effects of desert dust in respiratory epithelial cells and a murine model.
-
Biological evaluation of ring- and side-chain-substituted m-iodobenzylguanidine analogues.
-
Biological evaluation of some biphenyl analogs of acetyl-seco-hemicholinium No. 3.
-
Biological evaluation of some terphenyl analogs of hemicholinium No. 3.
-
Biological functions and transcriptional targets of CaRF in neurons.
-
Biological magnetic resonance imaging using laser-polarized 129Xe.
-
Biological responses to TGF-β in the mammary epithelium show a complex dependency on Smad3 gene dosage with important implications for tumor progression.
-
Biological, clinical and population relevance of 95 loci for blood lipids.
-
Biological, immunological, and biochemical evidence that HIX virus is a recombinant between Moloney leukemia virus and a murine xenotropic C type virus.
-
Biology of gliomas: potential clinical implications of glioma cellular heterogeneity.
-
Biology of hepatocellular neoplasia in the mouse. I. Histogenesis of safrole-induced hepatocellular carcinoma.
-
Biology of hepatocellular neoplasia in the mouse. II. Sequential enzyme histochemical analysis of BALB/c mouse liver during safrole-induced carcinogenesis.
-
Biology of hepatocellular neoplasia in the mouse. III. Electron microscopy of safrole-induced hepatocellular adenomas and hepatocellular carcinomas.
-
Biology of small cell lung cancer.
-
Bioluminescence imaging to track bacterial dissemination of Yersinia pestis using different routes of infection in mice.
-
Bioluminescence resonance energy transfer identify scaffold protein CNK1 interactions in intact cells.
-
Bioluminescent virion shells: new tools for quantitation of AAV vector dynamics in cells and live animals.
-
Biomaterial-mediated retroviral gene transfer using self-assembled monolayers.
-
Biomedicine. Insulin resistance takes a trip through the ER.
-
Biomimetic Hydrogels with Immobilized EphrinA1 for Therapeutic Angiogenesis
-
Biomimetic engineered muscle with capacity for vascular integration and functional maturation in vivo.
-
Biomimetic hydrogels with pro-angiogenic properties.
-
Biomimetic, synthetic HDL nanostructures for lymphoma.
-
Biophysical properties of the zona pellucida measured by capillary suction: is zona hardening a mechanical phenomenon?
-
Bioplasmonic calligraphy for multiplexed label-free biodetection.
-
Bioresorbable photonic devices for the spectroscopic characterization of physiological status and neural activity.
-
Biosynthesis and in vivo localization of the decapentaplegic-Vg-related protein, DVR-6 (bone morphogenetic protein-6).
-
Biosynthesis of long-chain (sphingoid) bases from serine by LM cells. Evidence for introduction of the 4-trans-double bond after de novo biosynthesis of N-acylsphinganine(s).
-
Biosynthesis of renin: multiplicity of active and intermediate forms.
-
Biosynthetically intriguing chlorinated lipophilic metabolites from geographically distant tropical marine cyanobacteria.
-
Biphasic functions for the GDNF-Ret signaling pathway in chemosensory neuron development and diversification.
-
Birinapant Enhances Gemcitabine's Antitumor Efficacy in Triple-Negative Breast Cancer by Inducing Intrinsic Pathway-Dependent Apoptosis.
-
Birthdays of retinal amacrine cell subtypes are systematically related to their molecular identity and soma position.
-
Bisphenol A delays the perinatal chloride shift in cortical neurons by epigenetic effects on the Kcc2 promoter.
-
Bisphenol A exposure alters placentation and causes preeclampsia-like features in pregnant mice involved in reprogramming of DNA methylation of WNT2.
-
Bisphosphate nucleotidase 2 (BPNT2), a molecular target of lithium, regulates chondroitin sulfation patterns in the cerebral cortex and hippocampus.
-
Bisphosphonates target B cells to enhance humoral immune responses.
-
Bitter melon reduces head and neck squamous cell carcinoma growth by targeting c-Met signaling.
-
Black cohosh increases metastatic mammary cancer in transgenic mice expressing c-erbB2.
-
Bladder sensory physiology: neuroactive compounds and receptors, sensory transducers, and target-derived growth factors as targets to improve function.
-
Blockade of T- and B-lymphocyte development by antibody to the gamma c subunit of the receptors for interleukins 2, 4, and 7.
-
Blockade of hyperbaric oxygen induced seizures by excitatory amino acid antagonists.
-
Blockade of nicotinic acetylcholine receptors suppresses hippocampal long-term potentiation in wild-type but not ApoE4 targeted replacement mice.
-
Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma.
-
Blockade of the natriuretic peptide clearance receptor attenuates proteinuria in a mouse model of focal segmental glomerulosclerosis.
-
Blocking CCL8-CCR8-Mediated Early Allograft Inflammation Improves Kidney Transplant Function.
-
Blocking CCR7 at the ocular surface impairs the pathogenic contribution of dendritic cells in allergic conjunctivitis.
-
Blocking Cyclin-Dependent Kinase 4/6 During Single Dose Versus Fractionated Radiation Therapy Leads to Opposite Effects on Acute Gastrointestinal Toxicity in Mice.
-
Blocking [211At]astatide accumulation in normal tissues: preliminary evaluation of seven potential compounds.
-
Blocking the apoE/Aβ interaction ameliorates Aβ-related pathology in APOE ε2 and ε4 targeted replacement Alzheimer model mice.
-
Blocking the interaction between apolipoprotein E and Aβ reduces intraneuronal accumulation of Aβ and inhibits synaptic degeneration.
-
Blood gene expression signatures predict invasive candidiasis.
-
Blood pressure homeostasis is maintained by a P311-TGF-β axis.
-
Blood pressure-associated polymorphism controls ARHGAP42 expression via serum response factor DNA binding.
-
Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis.
-
Blood-brain barrier (BBB) disruption using a diagnostic ultrasound scanner and Definity in Mice.
-
Blood-brain barrier dysfunction after primary blast injury in vitro.
-
Blood-derived inflammatory dendritic cells in lymph nodes stimulate acute T helper type 1 immune responses.
-
Blood-derived macrophages infiltrate the retina and activate Muller glial cells under experimental choroidal neovascularization.
-
Blunted stress responses in delayed type hypersensitivity in mice lacking the neuronal isoform of nitric oxide synthase.
-
Blurring the edges in vertebrate sex determination.
-
Bmp signaling is required for intestinal growth and morphogenesis.
-
Bmp signaling regulates proximal-distal differentiation of endoderm in mouse lung development.
-
Bmp4 and Fgf10 play opposing roles during lung bud morphogenesis.
-
Bmp4 is essential for the formation of the vestibular apparatus that detects angular head movements.
-
Bmp4 is required for the generation of primordial germ cells in the mouse embryo.
-
Bmp6 regulates retinal iron homeostasis and has altered expression in age-related macular degeneration.
-
Bmp7 regulates germ cell proliferation in mouse fetal gonads.
-
Bmps: multifunctional regulators of mammalian embryonic development.
-
Body weight and fat deposition in prolactin receptor-deficient mice.
-
Body weight is not always a good predictor of longevity in mice.
-
Bombesin and [Leu8]phyllolitorin promote fetal mouse lung branching morphogenesis via a receptor-mediated mechanism.
-
Bombesin increases fetal lung growth and maturation in utero and in organ culture.
-
Bombesin inhibits alveolarization and promotes pulmonary fibrosis in newborn mice.
-
Bombesin may play a role in fetal lung growth and maturation in utero and in lung organ culture.
-
Bombesin-like peptide receptor gene expression, regulation, and function in fetal murine lung.
-
Bombesin-like peptides and mast cell responses: relevance to bronchopulmonary dysplasia?
-
Bone Marrow Stress Decreases Osteogenic Progenitors.
-
Bone Marrow-Derived Monocytes Drive the Inflammatory Microenvironment in Local and Remote Regions after Thoracic Spinal Cord Injury.
-
Bone formation by human postnatal bone marrow stromal stem cells is enhanced by telomerase expression.
-
Bone formation induced by BMP-2 in human osteosarcoma cells.
-
Bone marrow chimeras and c-fms conditional ablation (Mafia) mice reveal an essential role for resident myeloid cells in lipopolysaccharide/TLR4-induced corneal inflammation.
-
Bone marrow dendritic cell-mediated regulation of TLR and B cell receptor signaling in B cells.
-
Bone marrow transplantation augments the effect of brain- and spinal cord-directed adeno-associated virus 2/5 gene therapy by altering inflammation in the murine model of globoid-cell leukodystrophy.
-
Bone marrow transplantation transfers age-related susceptibility to neovascular remodeling in murine laser-induced choroidal neovascularization.
-
Bone marrow-derived AXL tyrosine kinase promotes mitogenic crosstalk and cardiac allograft vasculopathy.
-
Bone marrow-derived dendritic cells pulsed with tumor homogenate induce immunity against syngeneic intracerebral glioma.
-
Bone marrow-derived mesenchymal stem cells undergo JCV T-antigen mediated transformation and generate tumors with neuroectodermal characteristics.
-
Bone marrow-derived progenitor cells contribute to experimental choroidal neovascularization.
-
Bone marrow-generated dendritic cells pulsed with tumor extracts or tumor RNA induce antitumor immunity against central nervous system tumors.
-
Bone morphogenetic protein 2 opposes Shh-mediated proliferation in cerebellar granule cells through a TIEG-1-based regulation of Nmyc.
-
Bone morphogenetic protein 4 in the extraembryonic mesoderm is required for allantois development and the localization and survival of primordial germ cells in the mouse.
-
Bone morphogenetic protein 4 mediates myocardial ischemic injury through JNK-dependent signaling pathway.
-
Bone morphogenetic protein 4 regulates the budding site and elongation of the mouse ureter.
-
Bone morphogenetic protein 8A plays a role in the maintenance of spermatogenesis and the integrity of the epididymis.
-
Bone morphogenetic protein signaling is required in the dorsal neural folds before neurulation for the induction of spinal neural crest cells and dorsal neurons.
-
Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse.
-
Bone morphogenetic proteins (BMPs) as regulators of dorsal forebrain development.
-
Bone targeting nanocarrier-assisted delivery of adenosine to combat osteoporotic bone loss.
-
Bone-related genes expressed in advanced malignancies induce invasion and metastasis in a genetically defined human cancer model.
-
Boosting cardiac contractility with genes.
-
Boosting high-intensity focused ultrasound-induced anti-tumor immunity using a sparse-scan strategy that can more effectively promote dendritic cell maturation.
-
Borg proteins control septin organization and are negatively regulated by Cdc42.
-
Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis.
-
Both Hematopoietic- and Non-hematopoietic-derived {beta}-arrestin-2 Regulates Murine Allergic Airway Disease.
-
Both selenium deficiency and modest selenium supplementation lead to myocardial fibrosis in mice via effects on redox-methylation balance.
-
Botulinum Neurotoxin A injections influence stretching of the gastrocnemius muscle-tendon unit in an animal model.
-
Bovine thrombin and systemic autoimmunity.
-
Brachytherapy using injectable seeds that are self-assembled from genetically encoded polypeptides in situ.
-
Brachytherapy via a depot of biopolymer-bound 131I synergizes with nanoparticle paclitaxel in therapy-resistant pancreatic tumours.
-
Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition.
-
Bradykinin produces pain hypersensitivity by potentiating spinal cord glutamatergic synaptic transmission.
-
Brain Metastasis Cell Lines Panel: A Public Resource of Organotropic Cell Lines.
-
Brain cancer stem cells display preferential sensitivity to Akt inhibition.
-
Brain inositol is a novel stimulator for promoting Cryptococcus penetration of the blood-brain barrier.
-
Brain insulin lowers circulating BCAA levels by inducing hepatic BCAA catabolism.
-
Brain natriuretic peptide improves long-term functional recovery after acute CNS injury in mice.
-
Brain stem as a target site for the metabolic side effects of olanzapine.
-
Brain tumors in man and animals: report of a workshop.
-
Brain tumors in mice are susceptible to blockade of epidermal growth factor receptor (EGFR) with the oral, specific, EGFR-tyrosine kinase inhibitor ZD1839 (iressa).
-
Brain-derived neurotrophic factor but not vesicular zinc promotes TrkB activation within mossy fibers of mouse hippocampus in vivo.
-
Brain-derived neurotrophic factor overexpression induces precocious critical period in mouse visual cortex.
-
Brain-specific carnitine palmitoyl-transferase-1c: role in CNS fatty acid metabolism, food intake, and body weight.
-
Brain-wide Electrical Spatiotemporal Dynamics Encode Depression Vulnerability.
-
Brain-wide electrical dynamics encode individual appetitive social behavior.
-
Branched-chain α-ketoacids are preferentially reaminated and activate protein synthesis in the heart.
-
Branching morphogenesis of the lung: new models for a classical problem.
-
Breadth of SARS-CoV-2 neutralization and protection induced by a nanoparticle vaccine.
-
Breaking or making immunological privilege in the central nervous system: the regulation of immunity by neuropeptides.
-
Brefeldin A rapidly disrupts plasma membrane polarity by blocking polar sorting in common endosomes of MDCK cells.
-
Bridged peptide macrocycles as ligands for PDZ domain proteins.
-
Bridging the translational gap: Implementation of multimodal small animal imaging strategies for tumor burden assessment in a co-clinical trial.
-
Broad immunophenotyping of the murine brain tumor microenvironment.
-
Bromelain treatment decreases neutrophil migration to sites of inflammation.
-
Bromodeoxyuridine-mediated radiosensitization in human glioma: the effect of concentration, duration, and fluoropyrimidine modulation.
-
Bronchial and bronchiolar fibrosis in rats exposed to 2,3-pentanedione vapors: implications for bronchiolitis obliterans in humans.
-
Bronchial epithelial injury in the context of alloimmunity promotes lymphocytic bronchiolitis through hyaluronan expression.
-
Bronchus-associated lymphoid tissue-resident Foxp3+ T lymphocytes prevent antibody-mediated lung rejection.
-
Brush border enzyme-cleavable linkers: Evaluation for reducing renal uptake of radiolabeled prostate-specific membrane antigen inhibitors.
-
Building and maintaining the epithelium of the lung.
-
Building and re-building the heart by cardiomyocyte proliferation.
-
Buprenorphine metabolites, buprenorphine-3-glucuronide and norbuprenorphine-3-glucuronide, are biologically active.
-
Burst-Dependent Bidirectional Plasticity in the Cerebellum Is Driven by Presynaptic NMDA Receptors.
-
Busulfan therapy of central nervous system xenografts in athymic mice.
-
Buthionine sulfoximine-mediated depletion of glutathione in intracranial human glioma-derived xenografts.
-
C-C Motif Chemokine 5 Attenuates Angiotensin II-Dependent Kidney Injury by Limiting Renal Macrophage Infiltration.
-
C-C Motif Chemokine Receptor 7 Exacerbates Hypertension Through Effects on T Lymphocyte Trafficking.
-
C-myc-induced apoptosis in polycystic kidney disease is Bcl-2 and p53 independent.
-
C-terminal deletion of the atrophin-1 protein results in growth retardation but not neurodegeneration in mice.
-
C-terminal regions of the human telomerase catalytic subunit essential for in vivo enzyme activity.
-
C-type virus particles in human urogenital tumours after heterotransplantation into nude mice.
-
C/EBPβ controls exercise-induced cardiac growth and protects against pathological cardiac remodeling.
-
C3orf58, a novel paracrine protein, stimulates cardiomyocyte cell-cycle progression through the PI3K-AKT-CDK7 pathway.
-
C8ORF37 Is Required for Photoreceptor Outer Segment Disc Morphogenesis by Maintaining Outer Segment Membrane Protein Homeostasis.
-
CAPER is vital for energy and redox homeostasis by integrating glucose-induced mitochondrial functions via ERR-α-Gabpa and stress-induced adaptive responses via NF-κB-cMYC.
-
CARHSP1 is required for effective tumor necrosis factor alpha mRNA stabilization and localizes to processing bodies and exosomes.
-
CARM1-expressing ovarian cancer depends on the histone methyltransferase EZH2 activity.
-
CBF, Myb, and Ets binding sites are important for activity of the core I element of the murine retrovirus SL3-3 in T lymphocytes.
-
CBX2 is required to stabilize the testis pathway by repressing Wnt signaling.
-
CCAAT/enhancer-binding protein alpha is required for transcription of the beta 3-adrenergic receptor gene during adipogenesis.
-
CCAAT/enhancer-binding protein beta deletion reduces adiposity, hepatic steatosis, and diabetes in Lepr(db/db) mice.
-
CCDC62/ERAP75 functions as a coactivator to enhance estrogen receptor beta-mediated transactivation and target gene expression in prostate cancer cells.
-
CCI-779 inhibits cell-cycle G2-M progression and invasion of castration-resistant prostate cancer via attenuation of UBE2C transcription and mRNA stability.
-
CCL-21 conditioned regulatory T cells induce allotolerance through enhanced homing to lymphoid tissue.
-
CCL5 promotes breast cancer recurrence through macrophage recruitment in residual tumors.
-
CCL5-mediated endogenous antitumor immunity elicited by adoptively transferred lymphocytes and dendritic cell depletion.
-
CCM1 and CCM2 protein interactions in cell signaling: implications for cerebral cavernous malformations pathogenesis.
-
CCN1 Regulates Chondrocyte Maturation and Cartilage Development.
-
CCP1 promotes mitochondrial fusion and motility to prevent Purkinje cell neuron loss in pcd mice.
-
CCR2 deficiency, dysregulation of Notch signaling, and spontaneous pulmonary arterial hypertension.
-
CCR2+ monocyte-derived dendritic cells and exudate macrophages produce influenza-induced pulmonary immune pathology and mortality.
-
CCR2-antagonist prophylaxis reduces pulmonary immune pathology and markedly improves survival during influenza infection.
-
CCR5 Signaling Promotes Murine and Human Hematopoietic Regeneration following Ionizing Radiation.
-
CCR7 is critical for the induction and maintenance of Th17 immunity in dry eye disease.
-
CD10/neutral endopeptidase 24.11 regulates fetal lung growth and maturation in utero by potentiating endogenous bombesin-like peptides.
-
CD11c(+)B220(+)Gr-1(+) cells in mouse lymph nodes and spleen display characteristics of plasmacytoid dendritic cells.
-
CD122-Selective IL2 Complexes Reduce Immunosuppression, Promote Treg Fragility, and Sensitize Tumor Response to PD-L1 Blockade.
-
CD122-directed interleukin-2 treatment mechanisms in bladder cancer differ from αPD-L1 and include tissue-selective γδ T cell activation.
-
CD14-dependent mechanism for endotoxin-mediated nitric oxide synthesis in murine macrophages.
-
CD19 amplification of B lymphocyte Ca2+ responses: a role for Lyn sequestration in extinguishing negative regulation.
-
CD19 amplifies B lymphocyte signal transduction by regulating Src-family protein tyrosine kinase activation.
-
CD19 and CD22 expression reciprocally regulates tyrosine phosphorylation of Vav protein during B lymphocyte signaling.
-
CD19 and CD22 regulate a B lymphocyte signal transduction pathway that contributes to autoimmunity.
-
CD19 can regulate B lymphocyte signal transduction independent of complement activation.
-
CD19 expression in B cells is important for suppression of contact hypersensitivity.
-
CD19 expression in B cells regulates atopic dermatitis in a mouse model.
-
CD19 expression levels regulate B lymphocyte development: human CD19 restores normal function in mice lacking endogenous CD19.
-
CD19 hyperexpression augments Sle1-induced humoral autoimmunity but not clinical nephritis.
-
CD19 maps to a region of conservation between human chromosome 16 and mouse chromosome 7.
-
CD19 regulates B lymphocyte responses to transmembrane signals.
-
CD19 regulates B lymphocyte signaling thresholds critical for the development of B-1 lineage cells and autoimmunity.
-
CD19 regulates Src family protein tyrosine kinase activation in B lymphocytes through processive amplification.
-
CD19 regulates innate immunity by the toll-like receptor RP105 signaling in B lymphocytes.
-
CD19 regulates skin and lung fibrosis via Toll-like receptor signaling in a model of bleomycin-induced scleroderma.
-
CD19 regulates the development of bleomycin-induced pulmonary fibrosis in a mouse model.
-
CD19, CD21, and CD22: multifaceted response regulators of B lymphocyte signal transduction.
-
CD19, a response regulator of B lymphocytes, regulates wound healing through hyaluronan-induced TLR4 signaling.
-
CD19-dependent B lymphocyte signaling thresholds influence skin fibrosis and autoimmunity in the tight-skin mouse.
-
CD19-regulated signaling thresholds control peripheral tolerance and autoantibody production in B lymphocytes.
-
CD19: a promising B cell target for rheumatoid arthritis.
-
CD20 deficiency in humans results in impaired T cell-independent antibody responses.
-
CD200+ cytotoxic T lymphocytes in the tumor microenvironment are crucial for efficacious anti-PD-1/PD-L1 therapy.
-
CD21/35 promotes protective immunity to Streptococcus pneumoniae through a complement-independent but CD19-dependent pathway that regulates PD-1 expression.
-
CD22 and CD72 cooperatively contribute to the development of the reverse Arthus reaction model.
-
CD22 expression mediates the regulatory functions of peritoneal B-1a cells during the remission phase of contact hypersensitivity reactions.
-
CD22 forms a quaternary complex with SHIP, Grb2, and Shc. A pathway for regulation of B lymphocyte antigen receptor-induced calcium flux.
-
CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice.
-
CD22 ligand binding regulates normal and malignant B lymphocyte survival in vivo.
-
CD22 negatively and positively regulates signal transduction through the B lymphocyte antigen receptor.
-
CD22 regulates B lymphocyte function in vivo through both ligand-dependent and ligand-independent mechanisms.
-
CD22 regulates time course of both B cell division and antibody response.
-
CD22 serves as a receptor for soluble IgM.
-
CD22, a B lymphocyte-specific adhesion molecule that regulates antigen receptor signaling.
-
CD22-Binding Synthetic Sialosides Regulate B Lymphocyte Proliferation Through CD22 Ligand-Dependent and Independent Pathways, and Enhance Antibody Production in Mice.
-
CD22: a multifunctional receptor that regulates B lymphocyte survival and signal transduction.
-
CD25+CD4+ regulatory T cell migration requires L-selectin expression: L-selectin transcriptional regulation balances constitutive receptor turnover.
-
CD26 inhibition enhances allogeneic donor-cell homing and engraftment after in utero hematopoietic-cell transplantation.
-
CD28 costimulatory signal induces protein arginine methylation in T cells.
-
CD28 is required for germinal center formation.
-
CD36-dependent signaling mediates fatty acid-induced gut release of secretin and cholecystokinin.
-
CD4 T Cell Help via B Cells Is Required for Lymphopenia-Induced CD8 T Cell Proliferation.
-
CD4 T-Cell Exhaustion: Does It Exist and What Are Its Roles in Cancer?
-
CD4 enhances T cell sensitivity to antigen by coordinating Lck accumulation at the immunological synapse.
-
CD4(+) T cells contribute to the remodeling of the microenvironment required for sustained tumor regression upon oncogene inactivation.
-
CD4+ T cells elicit host immune responses to MHC class II-negative ovarian cancer through CCL5 secretion and CD40-mediated licensing of dendritic cells.
-
CD4+CD25+Foxp3+ Tregs resolve experimental lung injury in mice and are present in humans with acute lung injury.
-
CD4+CD45RBHi T cell transfer induced colitis in mice is accompanied by osteopenia which is treatable with recombinant human osteoprotegerin.
-
CD4+Thy1- thymocytes with a Th-type 2 cytokine response.
-
CD44--a molecule involved in leukocyte adherence and T-cell activation.
-
CD47 blockade augmentation of trastuzumab antitumor efficacy dependent on antibody-dependent cellular phagocytosis.
-
CD47 halts Ptpn6
-deficient neutrophils from provoking lethal inflammation.
-
CD6.
-
CD62L- memory T cells enhance T-cell regeneration after allogeneic stem cell transplantation by eliminating host resistance in mice.
-
CD69 gene is differentially regulated in T and B cells by evolutionarily conserved promoter-distal elements.
-
CD7 and CD28 are required for murine CD4+CD25+ regulatory T cell homeostasis and prevention of thyroiditis.
-
CD8 positive T cells influence antigen-specific immune responses through the expression of chemokines.
-
CD8(+)NKR-P1A (+)T cells preferentially accumulate in human liver.
-
CD83 expression influences CD4+ T cell development in the thymus.
-
CD83 expression is a sensitive marker of activation required for B cell and CD4+ T cell longevity in vivo.
-
CD83 influences cell-surface MHC class II expression on B cells and other antigen-presenting cells.
-
CD83: a regulatory molecule of the immune system with great potential for therapeutic application.
-
CD86 (B7-2) can function to drive MHC-restricted antigen-specific CTL responses in vivo.
-
CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+ T cells.
-
CD98-induced CD147 signaling stabilizes the Foxp3 protein to maintain tissue homeostasis.
-
CDK2 activation in mouse epidermis induces keratinocyte proliferation but does not affect skin tumor development.
-
CDK4 regulation by TNFR1 and JNK is required for NF-kappaB-mediated epidermal growth control.
-
CDK5 regulates cell adhesion and migration in corneal epithelial cells.
-
CEA/CD3-bispecific T cell-engaging (BiTE) antibody-mediated T lymphocyte cytotoxicity maximized by inhibition of both PD1 and PD-L1.
-
CERKL interacts with mitochondrial TRX2 and protects retinal cells from oxidative stress-induced apoptosis.
-
CFLAR/c-FLIPL: a star in the autophagy, apoptosis and necroptosis alliance.
-
CFTR as a cAMP-dependent regulator of sodium channels.
-
CHD7 targets active gene enhancer elements to modulate ES cell-specific gene expression.
-
CHK1 protects oncogenic KRAS-expressing cells from DNA damage and is a target for pancreatic cancer treatment.
-
CHML promotes liver cancer metastasis by facilitating Rab14 recycle.
-
CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis.
-
CIP2A mediates erlotinib-induced apoptosis in non-small cell lung cancer cells without EGFR mutation.
-
CK1epsilon is required for breast cancers dependent on beta-catenin activity.
-
CK1δ/ε protein kinase primes the PER2 circadian phosphoswitch.
-
CLN3p impacts galactosylceramide transport, raft morphology, and lipid content.
-
CLN5 and CLN8 protein association with ceramide synthase: biochemical and proteomic approaches.
-
CNS inflammation and bone marrow neuropathy in type 1 diabetes.
-
CNS myelin wrapping is driven by actin disassembly.
-
CODAS syndrome is associated with mutations of LONP1, encoding mitochondrial AAA+ Lon protease.
-
COG1410, a novel apolipoprotein E-based peptide, improves functional recovery in a murine model of traumatic brain injury.
-
COUP-TFII regulates human endometrial stromal genes involved in inflammation.
-
COVA1-18 neutralizing antibody protects against SARS-CoV-2 in three preclinical models.
-
COX-2-derived prostacyclin modulates vascular remodeling.
-
CREB and ChREBP oppositely regulate SIRT1 expression in response to energy availability.
-
CRISPLD2 is a target of progesterone receptor and its expression is decreased in women with endometriosis.
-
CRISPR genome editing in stem cells turns to gold.
-
CRISPR/Cas9 Editing of Murine Induced Pluripotent Stem Cells for Engineering Inflammation-Resistant Tissues.
-
CSF1 receptor targeting in prostate cancer reverses macrophage-mediated resistance to androgen blockade therapy.
-
CSPG4 protein as a new target for the antibody-based immunotherapy of triple-negative breast cancer.
-
CTLA-4-Mediated inhibition of early events of T cell proliferation.
-
CVN-AD Alzheimer's mice show premature reduction in neurovascular coupling in response to spreading depression and anoxia compared to aged controls.
-
CX3CR1 deficiency impairs dendritic cell accumulation in arterial intima and reduces atherosclerotic burden.
-
CX3CR1+ interstitial dendritic cells form a contiguous network throughout the entire kidney.
-
CX3CR1-dependent renal macrophage survival promotes Candida control and host survival.
-
CXCL13 drives spinal astrocyte activation and neuropathic pain via CXCR5.
-
CXCR1-mediated neutrophil degranulation and fungal killing promote Candida clearance and host survival.
-
CXCR2 promotes ovarian cancer growth through dysregulated cell cycle, diminished apoptosis, and enhanced angiogenesis.
-
CXCR4 enhances adhesion of B16 tumor cells to endothelial cells in vitro and in vivo via beta(1) integrin.
-
CYLD deubiquitinates RIP1 in the TNFα-induced necrosome to facilitate kinase activation and programmed necrosis.
-
CYLD inhibits tumorigenesis and metastasis by blocking JNK/AP1 signaling at multiple levels.
-
CYP27A1 Loss Dysregulates Cholesterol Homeostasis in Prostate Cancer.
-
CYP2E1-dependent and leptin-mediated hepatic CD57 expression on CD8+ T cells aid progression of environment-linked nonalcoholic steatohepatitis.
-
CYP7B1: one cytochrome P450, two human genetic diseases, and multiple physiological functions.
-
Ca(2+)-regulated serine protease associated with the nuclear scaffold.
-
Ca(2+)/calmodulin-dependent protein kinase IV is expressed in spermatids and targeted to chromatin and the nuclear matrix.
-
Ca2+ entry via alpha1G and TRPV4 channels differentially regulates surface expression of P-selectin and barrier integrity in pulmonary capillary endothelium.
-
Ca2+/calmodulin-dependent protein kinase II (CaMKII) regulates cardiac sodium channel NaV1.5 gating by multiple phosphorylation sites.
-
CaMKII is essential for the proasthmatic effects of oxidation.
-
CaMKK2 Knockout Bone Marrow Cells Collected/Processed in Low Oxygen (Physioxia) Suggests CaMKK2 as a Hematopoietic Stem to Progenitor Differentiation Fate Determinant.
-
CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast cancer.
-
Cadherin-11 expressed in association with mesenchymal morphogenesis in the head, somite, and limb bud of early mouse embryos.
-
Cadherin-6 expression transiently delineates specific rhombomeres, other neural tube subdivisions, and neural crest subpopulations in mouse embryos.
-
Cadmium-induced DNA synthesis and cell proliferation in macrophages: the role of intracellular calcium and signal transduction mechanisms.
-
Cadmium-induced neoplastic transformation of human prostate epithelial cells.
-
Caffeine prevents restenosis and inhibits vascular smooth muscle cell proliferation through the induction of autophagy.
-
Caffeine stimulates hepatic lipid metabolism by the autophagy-lysosomal pathway in mice.
-
Calcineurin (CN) activation promotes apoptosis of glomerular podocytes both in vitro and in vivo.
-
Calcineurin activation causes retinal ganglion cell degeneration.
-
Calcineurin controls drug tolerance, hyphal growth, and virulence in Candida dubliniensis.
-
Calcineurin controls growth, morphology, and pathogenicity in Aspergillus fumigatus.
-
Calcineurin controls hyphal growth, virulence, and drug tolerance of Candida tropicalis.
-
Calcineurin enhances acetylcholinesterase mRNA stability during C2-C12 muscle cell differentiation.
-
Calcineurin governs thermotolerance and virulence of Cryptococcus gattii.
-
Calcineurin inhibition with systemic FK506 treatment increases dendritic branching and dendritic spine density in healthy adult mouse brain.
-
Calcineurin is essential for Candida albicans survival in serum and virulence.
-
Calcineurin is required for pseudohyphal growth, virulence, and drug resistance in Candida lusitaniae.
-
Calcineurin mediates pancreatic growth in protease inhibitor-treated mice.
-
Calcineurin mutants render T lymphocytes resistant to cyclosporin A.
-
Calcineurin orchestrates dimorphic transitions, antifungal drug responses and host-pathogen interactions of the pathogenic mucoralean fungus Mucor circinelloides.
-
Calcineurin promotes infection of the cornea by Candida albicans and can be targeted to enhance fluconazole therapy.
-
Calcineurin regulatory subunit is essential for virulence and mediates interactions with FKBP12-FK506 in Cryptococcus neoformans.
-
Calcineurin target CrzA regulates conidial germination, hyphal growth, and pathogenesis of Aspergillus fumigatus.
-
Calcineurin-NFAT signaling, together with GABP and peroxisome PGC-1{alpha}, drives utrophin gene expression at the neuromuscular junction.
-
Calcitonin driven v-Ha-ras induces multilineage pulmonary epithelial hyperplasias and neoplasms.
-
Calcitonin gene-related peptide (CGRP) in the developing mouse limb.
-
Calcitonin stimulation of renal 25-hydroxyvitamin D-1 alpha-hydroxylase activity in hypophosphatemic mice. Evidence that the regulation of calcitriol production is not universally abnormal in X-linked hypophosphatemia.
-
Calcium binding by synaptotagmin's C2A domain is an essential element of the electrostatic switch that triggers synchronous synaptic transmission.
-
Calcium binding domains and calcium-induced conformational transition of SPARC/BM-40/osteonectin, an extracellular glycoprotein expressed in mineralized and nonmineralized tissues.
-
Calcium dependent CAMTA1 in adult stem cell commitment to a myocardial lineage.
-
Calcium influx through L-type CaV1.2 Ca2+ channels regulates mandibular development.
-
Calcium, calmodulin and cell proliferation.
-
Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction.
-
Calcium-dependent cytosolic phospholipase A2 activation is implicated in neuroinflammation and oxidative stress associated with ApoE4.
-
Calcium-dependent cytosolic phospholipase A2 activation is implicated in neuroinflammation and oxidative stress associated with ApoE4.
-
Calcium-dependent regulation of cholecystokinin secretion and potassium currents in STC-1 cells.
-
Calcium/Calmodulin Dependent Protein Kinase Kinase 2 Regulates the Expansion of Tumor-Induced Myeloid-Derived Suppressor Cells.
-
Calcium/calmodulin-dependent kinase kinase 2 regulates hematopoietic stem and progenitor cell regeneration.
-
Calcium/calmodulin-dependent protein kinase kinase 2 regulates macrophage-mediated inflammatory responses.
-
Calcium/calmodulin-dependent protein kinase kinase 2: roles in signaling and pathophysiology.
-
Calibration-free absolute quantification of particle concentration by statistical analyses of photoacoustic signals in vivo.
-
Calibration-free structured-illumination photoacoustic flowgraphy of transverse flow in scattering media.
-
Calmodulin as a regulator of cell growth and gene expression.
-
Calmodulin as an integral subunit of phosphorylase kinase from rabbit skeletal muscle.
-
Calmodulin is involved in regulation of cell proliferation.
-
Calmodulin is required for cell-cycle progression during G1 and mitosis.
-
Calmodulin overexpression causes Ca(2+)-dependent apoptosis of pancreatic beta cells, which can be prevented by inhibition of nitric oxide synthase.
-
Calmodulin-dependent kinase IV links Toll-like receptor 4 signaling with survival pathway of activated dendritic cells.
-
Calmodulin-dependent protein kinase IV regulates hematopoietic stem cell maintenance.
-
Calmodulin-induced early-onset diabetes in transgenic mice.
-
Calmodulin-microtubule association in cultured mammalian cells.
-
Calorie restriction alleviates the age-related decrease in neural progenitor cell division in the aging brain.
-
Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation.
-
Calponin-3 deficiency augments contractile activity, plasticity, fibrogenic response and Yap/Taz transcriptional activation in lens epithelial cells and explants.
-
Calreticulin chaperones regulate functional expression of vomeronasal type 2 pheromone receptors.
-
Calreticulin displays in vivo peptide-binding activity and can elicit CTL responses against bound peptides.
-
Calspermin gene transcription is regulated by two cyclic AMP response elements contained in an alternative promoter in the calmodulin kinase IV gene.
-
Can Ceftazidime-Avibactam and Aztreonam Overcome β-Lactam Resistance Conferred by Metallo-β-Lactamases in Enterobacteriaceae?
-
Can the thymus win the battle against drug-resistant HIV?
-
Cancer clocks in tumourigenesis: the p53 pathway and beyond.
-
Cancer immunotherapy innovator James Allison receives the 2015 Lasker~DeBakey Clinical Medical Research Award.
-
Cancer in rodents: does it tell us about cancer in humans?
-
Cancer-Associated Fibroblasts Induce a Collagen Cross-link Switch in Tumor Stroma.
-
Cancer-cell-secreted exosomal miR-105 promotes tumour growth through the MYC-dependent metabolic reprogramming of stromal cells.
-
Cancer-specific type-I interferon receptor signaling promotes cancer stemness and effector CD8+ T-cell exhaustion.
-
Cannabinoids. Synthesis and central nervous system activity of 8-substituted 10-hydroxy-5,5-dimethyl-5H-[1]benzopyrano[4,3-c]pyridine and derivatives.
-
Canonical Inflammasomes Drive IFN-γ to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium.
-
Canonical Wnt signaling induces vascular endothelial dysfunction via p66Shc-regulated reactive oxygen species.
-
Canonical transient receptor potential 3 channels activate NF-κB to mediate allergic airway disease via PKC-α/IκB-α and calcineurin/IκB-β pathways.
-
Capillary isoelectric-focusing immunoassays to study dynamic oncoprotein phosphorylation and drug response to targeted therapies in non-small cell lung cancer.
-
Capric acid and hydroxypropylmethylcellulose increase the immunogenicity of nasally administered peptide vaccines.
-
Capsaicin vanilloid receptor-1 mediates substance P release in experimental pancreatitis.
-
Capture of phosphopeptides using alpha-zirconium phosphate nanoplatelets.
-
Capturing and Manipulating Activated Neuronal Ensembles with CANE Delineates a Hypothalamic Social-Fear Circuit.
-
Capturing the primordial Kras mutation initiating urethane carcinogenesis.
-
Car8 dorsal root ganglion expression and genetic regulation of analgesic responses are associated with a cis-eQTL in mice.
-
Carbohydrate Microarrays Identify Blood Group Precursor Cryptic Epitopes as Potential Immunological Targets of Breast Cancer.
-
Carbohydrate changes in pre- and peri-implantation mouse embryos as detected by a monoclonal antibody.
-
Carbohydrate recognition systems in amphibians: primitive alpha 2-macroglobulin receptors.
-
Carbohydrate restriction and lactate transporter inhibition in a mouse xenograft model of human prostate cancer.
-
Carbohydrate restriction, prostate cancer growth, and the insulin-like growth factor axis.
-
Carbon chain shape selectivity by the mouse olfactory receptor OR-I7.
-
Carbon monoxide and heme oxygenase-1 prevent intestinal inflammation in mice by promoting bacterial clearance.
-
Carbonic anhydrase-8 regulates inflammatory pain by inhibiting the ITPR1-cytosolic free calcium pathway.
-
Carbonylation of adipose proteins in obesity and insulin resistance: identification of adipocyte fatty acid-binding protein as a cellular target of 4-hydroxynonenal.
-
Carcinogen 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis is accelerated in Smad3 heterozygous mice compared to Smad3 wild type mice.
-
Carcinogen induced unscheduled DNA synthesis in mouse hepatocytes.
-
Carcinogenicity and toxicity of inhaled nitrobenzene in B6C3F1 mice and F344 and CD rats.
-
Carcinogenicity of inhaled benzene in CBA mice.
-
Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia.
-
Cardiac CaV1.2 channels require β subunits for β-adrenergic-mediated modulation but not trafficking.
-
Cardiac GPCRs: GPCR signaling in healthy and failing hearts.
-
Cardiac Pressure-Volume Loop Analysis Using Conductance Catheters in Mice.
-
Cardiac Troponin I-Interacting Kinase Affects Cardiomyocyte S-Phase Activity but Not Cardiomyocyte Proliferation.
-
Cardiac arrest and resuscitation activates the hypothalamic-pituitary-adrenal axis and results in severe immunosuppression.
-
Cardiac arrest/cardiopulmonary resuscitation augments cell-mediated immune function and transiently suppresses humoral immune function.
-
Cardiac beta ARK1 inhibition prolongs survival and augments beta blocker therapy in a mouse model of severe heart failure.
-
Cardiac cell therapy in vitro: reproducible assays for comparing the efficacy of different donor cells.
-
Cardiac copper deficiency activates a systemic signaling mechanism that communicates with the copper acquisition and storage organs.
-
Cardiac dysregulation following intrahippocampal kainate-induced status epilepticus.
-
Cardiac function in genetically engineered mice with altered adrenergic receptor signaling.
-
Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor.
-
Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor.
-
Cardiac gene expression profiling provides evidence for cytokinopathy as a molecular mechanism in Chagas' disease cardiomyopathy.
-
Cardiac hypertrophy and altered beta-adrenergic signaling in transgenic mice that express the amino terminus of beta-ARK1.
-
Cardiac hypertrophy and sudden death in mice with a genetically clamped renin transgene.
-
Cardiac micro-computed tomography for morphological and functional phenotyping of muscle LIM protein null mice.
-
Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family.
-
Cardiac overexpression of a G(q) inhibitor blocks induction of extracellular signal-regulated kinase and c-Jun NH(2)-terminal kinase activity in in vivo pressure overload.
-
Cardiac phenotype and angiotensin II levels in AT1a, AT1b, and AT2 receptor single, double, and triple knockouts.
-
Cardiac rupture after myocardial infarction: new insights from murine models.
-
Cardiac vulnerability to ischemia/reperfusion injury drastically increases in late pregnancy.
-
Cardiac-specific LIM protein FHL2 modifies the hypertrophic response to beta-adrenergic stimulation.
-
Cardiac-specific expression of heme oxygenase-1 protects against ischemia and reperfusion injury in transgenic mice.
-
Cardiac-specific mindin overexpression attenuates cardiac hypertrophy via blocking AKT/GSK3β and TGF-β1-Smad signalling.
-
Cardiac-specific overexpression of angiotensin II AT2 receptor causes attenuated response to AT1 receptor-mediated pressor and chronotropic effects.
-
Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies.
-
Cardiomyocyte-Specific Human Bcl2-Associated Anthanogene 3 P209L Expression Induces Mitochondrial Fragmentation, Bcl2-Associated Anthanogene 3 Haploinsufficiency, and Activates p38 Signaling.
-
Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues.
-
Cardioprotective and antiapoptotic effects of heme oxygenase-1 in the failing heart.
-
Cardioprotective effects of 70-kDa heat shock protein in transgenic mice.
-
Cardioprotective proteins upregulated in the liver in response to experimental myocardial ischemia.
-
Cardioprotective role of S-nitrosylated hemoglobin from rbc.
-
Cardiovascular Metabolomics.
-
Cardiovascular abnormalities in transgenic mice with reduced brown fat: an animal model of human obesity.
-
Cardiovascular phenotype of mice lacking all three subtypes of angiotensin II receptors.
-
Cardiovascular phenotyping of the mouse heart using a 4D radial acquisition and liposomal Gd-DTPA-BMA.
-
Cardiovascular responses to the isoprostanes iPF(2alpha)-III and iPE(2)-III are mediated via the thromboxane A(2) receptor in vivo.
-
Caribbean and La Réunion Chikungunya Virus Isolates Differ in Their Capacity To Induce Proinflammatory Th1 and NK Cell Responses and Acute Joint Pathology.
-
Carnitine revisited: potential use as adjunctive treatment in diabetes.
-
Cartilage tissue engineering: Directed differentiation of embryonic stem cells in three-dimensional hydrogel culture.
-
Cartilage tumours and bone development: molecular pathology and possible therapeutic targets.
-
Cartilage-Specific Knockout of the Mechanosensory Ion Channel TRPV4 Decreases Age-Related Osteoarthritis.
-
Cartilage-binding antibodies induce pain through immune complex-mediated activation of neurons.
-
Cartilage-specific RBPjκ-dependent and -independent Notch signals regulate cartilage and bone development.
-
Cartilage-specific β-catenin signaling regulates chondrocyte maturation, generation of ossification centers, and perichondrial bone formation during skeletal development.
-
Cas13d knockdown of lung protease Ctsl prevents and treats SARS-CoV-2 infection.
-
Casein kinase 1α-dependent feedback loop controls autophagy in RAS-driven cancers.
-
Casein kinase I in the mammalian circadian clock.
-
Caspase 3 promotes surviving melanoma tumor cell growth after cytotoxic therapy.
-
Caspase 3-mediated stimulation of tumor cell repopulation during cancer radiotherapy.
-
Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria.
-
Caspase-11 protects against bacteria that escape the vacuole.
-
Caspase-2 impacts lung tumorigenesis and chemotherapy response in vivo.
-
Caspase-2 promotes obesity, the metabolic syndrome and nonalcoholic fatty liver disease.
-
Caspase-3 cleavage links delta-catenin to the novel nuclear protein ZIFCAT.
-
Caspase-3 dependent cleavage and activation of skeletal muscle phosphorylase b kinase.
-
Caspase-3 promotes genetic instability and carcinogenesis.
-
Caspase-7 activates ASM to repair gasdermin and perforin pores.
-
Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death.
-
Caspase-8 and caspase-3 small interfering RNA decreases ischemia/reperfusion injury to the liver in mice.
-
Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology.
-
Caspase-dependent cleavage of carbamoyl phosphate synthetase II during apoptosis.
-
Catabolic Defect of Branched-Chain Amino Acids Promotes Heart Failure.
-
Catabolic pathways for streptokinase, plasmin, and streptokinase activator complex in mice. In vivo reaction of plasminogen activator with alpha 2-macroglobulin.
-
Catabolism of branched-chain amino acids in heart failure: insights from genetic models.
-
Catabolism of human tissue plasminogen activator in mice.
-
Catabolism of radioiodinated murine monoclonal antibody F(ab')2 fragment labeled using N-succinimidyl 3-iodobenzoate and Iodogen methods.
-
Catabolism of streptokinase and polyethylene glycol-streptokinase: evidence for transport of intact forms through the biliary system in the mouse.
-
Cataract in mice congenitally infected with Toxoplasma gondii.
-
Catecholamine synthesis is mediated by tyrosinase in the absence of tyrosine hydroxylase.
-
Catecholaminergic cell lines from the brain and adrenal glands of tyrosine hydroxylase-SV40 T antigen transgenic mice.
-
Catecholamines act via a beta-adrenergic receptor to maintain fetal heart rate and survival.
-
Cathelicidin-related antimicrobial peptide mediates skeletal muscle degeneration caused by injury and Duchenne muscular dystrophy in mice.
-
Cathepsin K-sensitive poly(ethylene glycol) hydrogels for degradation in response to bone resorption.
-
Cathepsin S causes inflammatory pain via biased agonism of PAR2 and TRPV4.
-
Caveats to the use of MTT, neutral red, Hoechst and Resazurin to measure silver nanoparticle cytotoxicity.
-
Caveolar and non-Caveolar Caveolin-1 in ocular homeostasis and disease.
-
Caveolin-1 modulates intraocular pressure: implications for caveolae mechanoprotection in glaucoma.
-
Cch1 mediates calcium entry in Cryptococcus neoformans and is essential in low-calcium environments.
-
Ccm1 is required for arterial morphogenesis: implications for the etiology of human cavernous malformations.
-
Cdc2 and Mos regulate Emi2 stability to promote the meiosis I-meiosis II transition.
-
Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells.
-
Cdk2 deficiency decreases ras/CDK4-dependent malignant progression, but not myc-induced tumorigenesis.
-
Ceftaroline: a cephalosporin with expanded Gram-positive activity.
-
Ceftriaxone pharmacokinetics in interleukin-10-treated murine pneumococcal pneumonia.
-
Celecoxib does not delay cutaneous wound healing in haemophilia B mice.
-
Celecoxib inhibits vascular endothelial growth factor expression in and reduces angiogenesis and metastasis of human pancreatic cancer via suppression of Sp1 transcription factor activity.
-
Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model.
-
Cell adhesion: separation of p120's powers?
-
Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth.
-
Cell binding and tumor inhibiting functions of a new antihuman melanoma murine monoclonal antibody.
-
Cell binding specificity of mouse R-cadherin and chromosomal mapping of the gene.
-
Cell biology. Propelling progeny.
-
Cell culture models to study retinal pigment epithelium-related pathogenesis in age-related macular degeneration.
-
Cell cycle-independent death of prostate adenocarcinoma is induced by the trk tyrosine kinase inhibitor CEP-751 (KT6587).
-
Cell death in age-related macular degeneration.
-
Cell interactions and endoderm differentiation in cultured mouse embryos.
-
Cell interactions modulate embryonal carcinoma cell differentiation into parietal or visceral endoderm.
-
Cell lineage mapping of taste bud cells and keratinocytes in the mouse tongue and soft palate.
-
Cell membrane-anchored and tumor-targeted IL-12 (attIL12)-T cell therapy for eliminating large and heterogeneous solid tumors.
-
Cell non-autonomous requirement of p75 in the development of geniculate oral sensory neurons.
-
Cell population dynamics model for deconvolution of murine embryonic stem cell self-renewal and differentiation responses to cytokines and extracellular matrix.
-
Cell proliferation is necessary for the determination of male fate in the gonad.
-
Cell surface localization and density of the tumor-associated variant of the epidermal growth factor receptor, EGFRvIII.
-
Cell surface-associated proteins which bind native type IV collagen or gelatin.
-
Cell therapy for diverse central nervous system disorders: inherited metabolic diseases and autism.
-
Cell therapy in murine atherosclerosis: in vivo imaging with high-resolution helical SPECT.
-
Cell type-specific effects of Notch signaling activation on intervertebral discs: Implications for intervertebral disc degeneration.
-
Cell wall chitosan is necessary for virulence in the opportunistic pathogen Cryptococcus neoformans.
-
Cell-Compatible, Site-Specific Covalent Modification of Hydrogel Scaffolds Enables User-Defined Control over Cell-Material Interactions.
-
Cell-Specific Actions of the Prostaglandin E-Prostanoid Receptor 4 Attenuating Hypertension: A Dominant Role for Kidney Epithelial Cells Compared With Macrophages.
-
Cell-autonomous activation of the PI3-kinase pathway initiates endometrial cancer from adult uterine epithelium.
-
Cell-autonomous adiposity through increased cell surface GLUT4 due to ankyrin-B deficiency.
-
Cell-based gene therapy for repair of critical size defects in the rat fibula.
-
Cell-based vaccines for the stimulation of immunity to metastatic cancers.
-
Cell-cell adhesions and cell contractility are upregulated upon desmosome disruption.
-
Cell-cell interactions and bronchoconstrictor eicosanoid reduction with inhaled carbon monoxide and resolvin D1.
-
Cell-dependent posttranslational processing and secretion of recombinant mouse renin-2.
-
Cell-mediated cytotoxicity of murine cytomegalovirus-infected target cells allows for release of residual infectious virus.
-
Cell-programmed nutrient partitioning in the tumour microenvironment.
-
Cell-specific constraints to the lateral diffusion of a membrane glycoprotein.
-
Cell-surface co-receptors: emerging roles in signaling and human disease.
-
Cell-type specific regulation of gene expression by simian virus 40 T antigens.
-
Cells en route to apoptosis are characterized by the upregulation of c-fos, c-myc, c-jun, cdc2, and RB phosphorylation, resembling events of early cell-cycle traverse.
-
Cells of renin lineage are progenitors of podocytes and parietal epithelial cells in experimental glomerular disease.
-
Cells treated with TAP-2 antisense oligonucleotides are potent antigen-presenting cells in vitro and in vivo.
-
Cellular FLIP Inhibits Myeloid Cell Activation by Suppressing Selective Innate Signaling.
-
Cellular Sites and Mechanisms Linking Reduction of Dipeptidyl Peptidase-4 Activity to Control of Incretin Hormone Action and Glucose Homeostasis.
-
Cellular and functional defects in a mouse model of heart failure.
-
Cellular and molecular responses of the uterus to embryo implantation can be elicited by locally applied growth factors.
-
Cellular and viral splicing factors can modify the splicing pattern of CFTR transcripts carrying splicing mutations.
-
Cellular crosstalk regulates the aqueous humor outflow pathway and provides new targets for glaucoma therapies.
-
Cellular cytoskeleton dynamics modulates non-viral gene delivery through RhoGTPases
-
Cellular determinants of reduced adaptability of the aging brain: neurotransmitter utilization and cell signaling responses after MDMA lesions.
-
Cellular engineering for the treatment of metabolic disorders: prospects for therapy in diabetes.
-
Cellular gene expression in papillomas of the choroid plexus from transgenic mice that express the simian virus 40 large T antigen.
-
Cellular glycan modification by B3GAT1 broadly restricts influenza virus infection.
-
Cellular immune response to cryptic epitopes during therapeutic gene transfer.
-
Cellular immune responses in neonates.
-
Cellular inhibitor of apoptosis 2 (cIAP2) restricts neuroinflammation during experimental autoimmune encephalomyelitis.
-
Cellular interaction in germinal centers. Roles of CD40 ligand and B7-2 in established germinal centers.
-
Cellular interactions implicated in the mechanism of photoreceptor degeneration in transgenic mice expressing a mutant rhodopsin gene.
-
Cellular patterns of insulin-like growth factor system gene expression in murine chondrogenesis and osteogenesis.
-
Cellular redox modulator, ortho Mn(III) meso-tetrakis(N-n-hexylpyridinium-2-yl)porphyrin, MnTnHex-2-PyP(5+) in the treatment of brain tumors.
-
Cellular requirements for anti-DNA production induced in mice by immunization with bacterial DNA.
-
Cellular response to phase-separated blends of tyrosine-derived polycarbonates.
-
Cellular serine proteinase induces chemotaxis by complement activation.
-
Cellular stress signaling activates type-I IFN response through FOXO3-regulated lamin posttranslational modification.
-
Central and peripheral effects of insulin/IGF-1 signaling in aging and cancer: antidiabetic drugs as geroprotectors and anticarcinogens.
-
Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells.
-
Central nervous system imprinting of the G protein G(s)alpha and its role in metabolic regulation.
-
Central tolerance regulates B cells reactive with Goodpasture antigen alpha3(IV)NC1 collagen.
-
Centrifugal migration of mesenchymal cells in embryonic lung.
-
Ceramide mediates nanovesicle shedding and cell death in response to phosphatidylinositol ether lipid analogs and perifosine.
-
Cerebellar defects in Ca2+/calmodulin kinase IV-deficient mice.
-
Cerebral Cavernous Malformations Develop Through Clonal Expansion of Mutant Endothelial Cells.
-
Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican.
-
Cerebroside sulfotransferase deficiency ameliorates L-selectin-dependent monocyte infiltration in the kidney after ureteral obstruction.
-
Cerium Oxide Nanoparticles: A Potential Medical Countermeasure to Mitigate Radiation-Induced Lung Injury in CBA/J Mice.
-
Ceruloplasmin/hephaestin knockout mice model morphologic and molecular features of AMD.
-
Cervical Vagus Nerve Stimulation Improves Neurologic Outcome After Cardiac Arrest in Mice by Attenuating Oxidative Stress and Excessive Autophagy.
-
Cervicovaginal secretions contribute to innate resistance to herpes simplex virus infection.
-
Cessation of biomechanical stretch model of C2C12 cells models myocyte atrophy and anaplerotic changes in metabolism using non-targeted metabolomics analysis.
-
ChREBP regulates fructose-induced glucose production independently of insulin signaling.
-
Challenges of comparative expression profiling studies of complex diseases: mouse models of myocardial hypertrophy. Focus on "Divergent transcriptional responses to independent genetic causes of cardiac hypertrophy".
-
Changes in Hepatic TRβ Protein Expression, Lipogenic Gene Expression, and Long-Chain Acylcarnitine Levels During Chronic Hyperthyroidism and Triiodothyronine Withdrawal in a Mouse Model.
-
Changes in macroautophagy, chaperone-mediated autophagy, and mitochondrial metabolism in murine skeletal and cardiac muscle during aging.
-
Changes in macrophages and their functions with aging in C57BL/6J, AKR/J, and SJL/J mice.
-
Changes in magnetization transfer MRI correlate with spreading depression-induced astroglial reactivity and increased protein expression in mice.
-
Changes in the behaviour of teratocarcinoma cells cultivated in vitro.
-
Changes in the binding of "fast"-form alpha 2-macroglobulin to 3T3-L1 cells after differentiation to adipocytes.
-
Changes in the dendritic branching of adult mammalian neurones revealed by repeated imaging in situ.
-
Changes in the rate of laminin and entactin synthesis in F9 embryonal carcinoma cells treated with retinoic acid and cyclic amp.
-
Characterisation of systemic dissemination of nonreplicating adenoviral vectors from tumours in local gene delivery.
-
Characteristics of Vibration that Alter Cardiovascular Parameters in Mice.
-
Characteristics of sequential activity in networks with temporally asymmetric Hebbian learning.
-
Characterization and Functional Phenotyping of Renal Immune Cells via Flow Cytometry.
-
Characterization and comparison of commercially available antinuclear antibody kits using single pattern index sera.
-
Characterization and expression of a rice RAD23 gene.
-
Characterization and expression of the complementary DNA encoding rat histidine decarboxylase.
-
Characterization and identification of measurable endpoints in a mouse model featuring age-related retinal pathologies: a platform to test therapies.
-
Characterization and identification of measurable endpoints in a mouse model featuring age-related retinal pathologies: a platform to test therapies.
-
Characterization and idiotypic analysis of an anti-RNP monoclonal antibody.
-
Characterization and initial demonstration of in vivo efficacy of a novel heat-activated metalloenediyne anti-cancer agent.
-
Characterization and optimization of RGD-containing silk blends to support osteoblastic differentiation.
-
Characterization and regulation of the trehalose synthesis pathway and its importance in the pathogenicity of Cryptococcus neoformans.
-
Characterization and solubilization of pyrrole-imidazole polyamide aggregates.
-
Characterization and tissue expression of multiple triiodothyronine receptor-auxiliary proteins and their relationship to the retinoid X-receptors.
-
Characterization of 67 kD laminin receptor, a protein whose gene is overexpressed on treatment of cells with anti-benzo[a]pyrene-7,8-diol-9,10-epoxide.
-
Characterization of Adipogenic Activity of House Dust Extracts and Semi-Volatile Indoor Contaminants in 3T3-L1 Cells.
-
Characterization of Adipogenic Chemicals in Three Different Cell Culture Systems: Implications for Reproducibility Based on Cell Source and Handling.
-
Characterization of Ca2+/calmodulin-dependent protein kinase IV. Role in transcriptional regulation.
-
Characterization of Fatty Acid Binding Protein 7 (FABP7) in the Murine Retina.
-
Characterization of Langerin-expressing dendritic cell subsets in the normal cornea.
-
Characterization of NO and cytokine production in immune-activated microglia and peritoneal macrophages derived from a mouse model expressing the human NOS2 gene on a mouse NOS2 knockout background.
-
Characterization of PDK2 activity against protein kinase B gamma.
-
Characterization of Per- and Polyfluorinated Alkyl Substances Present in Commercial Anti-fog Products and Their In Vitro
Adipogenic Activity.
-
Characterization of Plasmodium liver stage inhibition by halofuginone.
-
Characterization of XIAP-deficient mice.
-
Characterization of a CD6 ligand(s) expressed on human- and murine-derived cell lines and murine lymphoid tissues.
-
Characterization of a CNS cell line, CAD, in which morphological differentiation is initiated by serum deprivation.
-
Characterization of a castrate-resistant prostate cancer xenograft derived from a patient of West African ancestry.
-
Characterization of a gene trap insertion into a novel gene, cordon-bleu, expressed in axial structures of the gastrulating mouse embryo.
-
Characterization of a human prostate adenocarcinoma cell line (DU 145) as a monolayer culture and as a solid tumor in athymic mice.
-
Characterization of a monoclonal antibody (5E9) that defines a human cell surface antigen of cell activation.
-
Characterization of a murine monoclonal antibody that mimics heparin-induced thrombocytopenia antibodies.
-
Characterization of a novel human corneal endothelial antigen.
-
Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells.
-
Characterization of a recovery global cerebral ischemia model in the mouse.
-
Characterization of a spontaneous murine astrocytoma and abrogation of its tumorigenicity by cytokine secretion.
-
Characterization of a thymus-tropic HIV-1 isolate from a rapid progressor: role of the envelope.
-
Characterization of alpha 2-macroglobulin-plasmin complexes: complete subunit cleavage alters receptor recognition in vivo and in vitro.
-
Characterization of an oxaliplatin sensitivity predictor in a preclinical murine model of colorectal cancer.
-
Characterization of and osteoarthritis susceptibility in ADAMTS-4-knockout mice.
-
Characterization of angiotensin II-receptor subtypes in podocytes.
-
Characterization of antibodies to canine renal renin. Studies of interspecies homology of renin using antibodies as probe.
-
Characterization of antiestrogenic activity of the Chinese herb, prunella vulgaris, using in vitro and in vivo (Mouse Xenograft) models.
-
Characterization of basal pseudopod-like processes in ileal and colonic PYY cells.
-
Characterization of cDNA encoding mouse DNA repair protein O6-methylguanine-DNA methyltransferase and high-level expression of the wild-type and mutant proteins in Escherichia coli.
-
Characterization of cardiovascular injury in mice following partial-heart irradiation with clinically relevant dose and fractionation.
-
Characterization of cord blood natural killer and lymphokine activated killer lymphocytes following ex vivo cellular engineering.
-
Characterization of cytotoxic cells generated from in vitro cultures of murine bone marrow cells.
-
Characterization of delta opioid receptors in lung cancer using a novel nonpeptidic ligand.
-
Characterization of effector T cells in dry eye disease.
-
Characterization of elongation factor-1A (eEF1A-1) and eEF1A-2/S1 protein expression in normal and wasted mice.
-
Characterization of functional human alpha 2-macroglobulin half-molecules isolated by limited reduction with dithiothreitol.
-
Characterization of glomerular thromboxane receptors in murine lupus nephritis.
-
Characterization of human CD7 transgenic mice.
-
Characterization of insulin-like growth factor-binding protein-related proteins (IGFBP-rPs) 1, 2, and 3 in human prostate epithelial cells: potential roles for IGFBP-rP1 and 2 in senescence of the prostatic epithelium.
-
Characterization of intraocular immunopathology following intracameral inoculation with alloantigen.
-
Characterization of lens fiber cell triton insoluble fraction reveals ERM (ezrin, radixin, moesin) proteins as major cytoskeletal-associated proteins.
-
Characterization of liver GSD IX γ2 pathophysiology in a novel Phkg2-/- mouse model.
-
Characterization of moesin in the sea urchin Lytechinus variegatus: redistribution to the plasma membrane following fertilization is inhibited by cytochalasin B.
-
Characterization of monoclonal antibodies with specificity for DNA and the synthetic polypeptide antigen (T,G)-A-L.
-
Characterization of murine peritoneal macrophage receptors for fibrin(ogen) degradation products.
-
Characterization of nanoprobe uptake in single cells: spatial and temporal tracking via SERS labeling and modulation of surface charge.
-
Characterization of neuronal/glial differentiation of murine adipose-derived adult stromal cells.
-
Characterization of new gangliosides of the lactotetraose series in murine xenografts of a human glioma cell line.
-
Characterization of potential precursor populations in the mouse olfactory epithelium using immunocytochemistry and autoradiography.
-
Characterization of prostatic epithelial cell lines derived from transgenic adenocarcinoma of the mouse prostate (TRAMP) model.
-
Characterization of senescence- and apoptosis-dependent forms of terminin as derived from a precursor found in replicating and nonreplicating cells.
-
Characterization of short range DNA looping in endotoxin-mediated transcription of the murine inducible nitric-oxide synthase (iNOS) gene.
-
Characterization of subtle brain abnormalities in a mouse model of Hedgehog pathway antagonist-induced cleft lip and palate.
-
Characterization of the axon initial segment of mice substantia nigra dopaminergic neurons.
-
Characterization of the distinct orthotopic bone-forming activity of 14 BMPs using recombinant adenovirus-mediated gene delivery.
-
Characterization of the effect of hyperthermia on nanoparticle extravasation from tumor vasculature.
-
Characterization of the effects of endotoxin on macrophage tumor cell killing.
-
Characterization of the epidermal growth factor receptor in human glioma cell lines and xenografts.
-
Characterization of the immune response to the major glycoprotein (gp 71) of Friend leukemia virus. I. Response in BALB/c mice.
-
Characterization of the immune response to the major glycoprotein (gp71) of Friend leukemia virus. II. Response in C57BL/6 mice.
-
Characterization of the immune response to the major glycoprotein (gp71) of Friend leukemia virus. III. Influence on endogenous MuLV-mediated pathogenesis.
-
Characterization of the insulinotropic potency of polyunsaturated fatty acids.
-
Characterization of the mechanisms of busulfan resistance in a human glioblastoma multiforme xenograft.
-
Characterization of the mouse FTZ-F1 gene, which encodes a key regulator of steroid hydroxylase gene expression.
-
Characterization of the mouse SPARC/osteonectin gene. Intron/exon organization and an unusual promoter region.
-
Characterization of the mouse transforming growth factor alpha gene: its expression during eyelid development and in waved 1 tissues.
-
Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal.
-
Characterization of the role of the amino-terminal proline in the enzymatic activity catalyzed by macrophage migration inhibitory factor.
-
Characterization of the serum In(Lu)-related antigen: identification of a serum protein related to erythrocyte p80.
-
Characterization of the tissue regression process in the uterus of older mice as apoptotic by the presence of Tp30, an isoform of terminin.
-
Characterization of the trans-activation properties of equine herpesvirus 1 EICP0 protein.
-
Characterization of the ubiquitin-modified proteome regulated by transient forebrain ischemia.
-
Characterization of three restricted specificity monoclonal antibodies raised against the human glioma cell line D-54 MG.
-
Characterization of tumor-specific cytotoxic effector cells with a novel CD3-/Thy-1+ phenotype.
-
Characterizing the Potency and Impact of Carbon Ion Therapy in a Primary Mouse Model of Soft Tissue Sarcoma.
-
Chelation, formulation, encapsulation, retention, and in vivo biodistribution of hydrophobic nanoparticles labelled with 57
Co-porphyrin: Oleylamine ensures stable chelation of cobalt in nanoparticles that accumulate in tumors.
-
Chemerin suppresses hepatocellular carcinoma metastasis through CMKLR1-PTEN-Akt axis.
-
Chemerin-activated functions of CMKLR1 are regulated by G protein-coupled receptor kinase 6 (GRK6) and β-arrestin 2 in inflammatory macrophages.
-
Chemical and structural modifications of alpha 2-macroglobulin: effects on receptor binding and endocytosis studied in an in vivo model.
-
Chemical denervation with botulinum neurotoxin a improves the surgical manipulation of the muscle-tendon unit: an experimental study in an animal model.
-
Chemical evidence for early but unsustained growth in the obstructed mouse kidney.
-
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury.
-
Chemical interrogation of the malaria kinome.
-
Chemical knockout of pantothenate kinase reveals the metabolic and genetic program responsible for hepatic coenzyme A homeostasis.
-
Chemical modification and site-directed mutagenesis of conserved HXXH and PP-loop motif arginines and histidines in the murine bifunctional ATP sulfurylase/adenosine 5'-phosphosulfate kinase.
-
Chemical pancreatectomy: an unconventional approach to preventing autodigestion in pancreatitis.
-
Chemical sintering generates uniform porous hyaluronic acid hydrogels
-
Chemical skin carcinogenesis is prevented in mice by the induced expression of a TGF-beta related transgene.
-
Chemical structure of carbamoylating groups and their relationship to bone marrow toxicity and antiglioma activity of bifunctionally alkylating and carbamoylating nitrosoureas.
-
Chemico-genetic discovery of astrocytic control of inhibition in vivo.
-
Chemogenetics-mediated acute inhibition of excitatory neuronal activity improves stroke outcome.
-
Chemokine CXCL1 enhances inflammatory pain and increases NMDA receptor activity and COX-2 expression in spinal cord neurons via activation of CXCR2.
-
Chemokine receptor CCR5 promotes leukocyte trafficking to the brain and survival in West Nile virus infection.
-
Chemokines and B-cell homing to follicles.
-
Chemoprevention of pancreatic cancer: ready for the clinic?
-
Chemopreventive apigenin controls UVB-induced cutaneous proliferation and angiogenesis through HuR and thrombospondin-1.
-
Chemotactic factor and P15E-related chemotaxis inhibitor in human melanoma cell lines with different macrophage content and tumorigenicity in nude mice.
-
Chemotherapy Induces Programmed Cell Death-Ligand 1 Overexpression via the Nuclear Factor-κB to Foster an Immunosuppressive Tumor Microenvironment in Ovarian Cancer.
-
Chemotherapy and radiation therapy of human medulloblastoma in athymic nude mice.
-
Chemotherapy of subcutaneous and intracranial human medulloblastoma xenografts in athymic nude mice.
-
Chemotherapy-Induced Depletion of OCT4-Positive Cancer Stem Cells in a Mouse Model of Malignant Testicular Cancer.
-
Chicken calmodulin promoter activity in proliferating and differentiated cells.
-
Chikungunya virus neutralization antigens and direct cell-to-cell transmission are revealed by human antibody-escape mutants.
-
Chikungunya virus nsP3 & nsP4 interacts with HSP-90 to promote virus replication: HSP-90 inhibitors reduce CHIKV infection and inflammation in vivo.
-
Chimeric NKG2D receptor-bearing T cells as immunotherapy for ovarian cancer.
-
Chimeric Sindbis/eastern equine encephalitis vaccine candidates are highly attenuated and immunogenic in mice.
-
Chimeric alphavirus vaccine candidates for chikungunya.
-
Chimeric anti-tenascin antibody 81C6: increased tumor localization compared with its murine parent.
-
Chimeric spike mRNA vaccines protect against sarbecovirus challenge in mice
-
Chitosan Biosynthesis and Virulence in the Human Fungal Pathogen Cryptococcus gattii.
-
Chitosan Derivatives Active against Multidrug-Resistant Bacteria and Pathogenic Fungi: In Vivo Evaluation as Topical Antimicrobials.
-
Chlamydia muridarum evades growth restriction by the IFN-gamma-inducible host resistance factor Irgb10.
-
Chlamydia repurposes the actin-binding protein EPS8 to disassemble epithelial tight junctions and promote infection.
-
Chlamydia trachomatis Infection Leads to Defined Alterations to the Lipid Droplet Proteome in Epithelial Cells.
-
Chlamydia trachomatis Is Resistant to Inclusion Ubiquitination and Associated Host Defense in Gamma Interferon-Primed Human Epithelial Cells.
-
Chloroform inhalation exposure conditions necessary to initiate liver toxicity in female B6C3F1 mice.
-
Chloroquine improves survival and hematopoietic recovery after lethal low-dose-rate radiation.
-
Chloroquine, quinine and quinidine inhibit calcium release from macrophage intracellular stores by blocking inositol 1,4,5-trisphosphate binding to its receptor.
-
Cholecystokinin is not a peripheral satiety signal in the dog.
-
Cholera toxin acts as a potent adjuvant for the induction of cytotoxic T-lymphocyte responses with non-replicating antigens.
-
Cholera toxin and cell growth: role of membrane gangliosides.
-
Cholesterol-induced macrophage apoptosis requires ER stress pathways and engagement of the type A scavenger receptor.
-
Choline attenuates inflammatory hyperalgesia activating nitric oxide/cGMP/ATP-sensitive potassium channels pathway.
-
Choline availability during embryonic development alters the localization of calretinin in developing and aging mouse hippocampus.
-
Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis.
-
Cholinergic augmentation of insulin release requires ankyrin-B.
-
Cholinergic neurons constitutively engage the ISR for dopamine modulation and skill learning in mice.
-
Cholinergic regulatory lymphocytes re-establish neuromodulation of innate immune responses in sepsis.
-
Chondrocyte-Specific RUNX2 Overexpression Accelerates Post-traumatic Osteoarthritis Progression in Adult Mice.
-
Chondrogenic potential of adipose tissue-derived stromal cells in vitro and in vivo.
-
Chondroprotective role of the osmotically sensitive ion channel transient receptor potential vanilloid 4: age- and sex-dependent progression of osteoarthritis in Trpv4-deficient mice.
-
Chordin and noggin promote organizing centers of forebrain development in the mouse.
-
Chordin is a modifier of tbx1 for the craniofacial malformations of 22q11 deletion syndrome phenotypes in mouse.
-
Chromatin Remodeling of Colorectal Cancer Liver Metastasis is Mediated by an HGF-PU.1-DPP4 Axis.
-
Chromatin architecture, CCCTC-binding factor, and V(D)J recombination: managing long-distance relationships at antigen receptor loci.
-
Chromatin-bound p53 anchors activated Smads and the mSin3A corepressor to confer transforming-growth-factor-beta-mediated transcription repression.
-
Chromium (VI) at plausible drinking water concentrations is not genotoxic in the in vivo bone marrow micronucleus or liver unscheduled DNA synthesis assays.
-
Chromium(VI) induces p53-dependent apoptosis in diploid human lung and mouse dermal fibroblasts.
-
Chromosomal assignment of the murine Gi alpha and Gs alpha genes. Implications for the obese mouse.
-
Chromosomal assignments of the genes coding for human types II, III, and IV collagen: a dispersed gene family.
-
Chromosomal composition of malignant human gliomas through serial subcutaneous transplantation in athymic mice.
-
Chromosomal localization of seven members of the murine TGF-beta superfamily suggests close linkage to several morphogenetic mutant loci.
-
Chromosomal localization of the ankyrinG gene (ANK3/Ank3) to human 10q21 and mouse 10.
-
Chromosomal localization of the mouse Src-like adapter protein (Slap) gene and its putative human homolog SLA.
-
Chromosomal organization of adrenergic receptor genes.
-
Chromosome mapping of human cell surface molecules: monoclonal anti-human lymphocyte antibodies 4F2, A3D8, and A1G3 define antigens controlled by different regions of chromosome 11.
-
Chronic Alcohol Ingestion Delays T Cell Activation and Effector Function in Sepsis.
-
Chronic Ethanol Metabolism Inhibits Hepatic Mitochondrial Superoxide Dismutase via Lysine Acetylation.
-
Chronic activation of the kinase IKKβ impairs T cell function and survival.
-
Chronic aspiration shifts the immune response from Th1 to Th2 in a murine model of asthma.
-
Chronic aspiration shifts the immune response from adaptive immunity to innate immunity in a murine model of asthma.
-
Chronic axial compression of the mouse tail segment induces MRI bone marrow edema changes that correlate with increased marrow vasculature and cellularity.
-
Chronic caloric restriction maintains a youthful phosphoproteome in aged skeletal muscle.
-
Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer.
-
Chronic dry eye disease is principally mediated by effector memory Th17 cells.
-
Chronic elevation of calmodulin in the ventricles of transgenic mice increases the autonomous activity of calmodulin-dependent protein kinase II, which regulates atrial natriuretic factor gene expression.
-
Chronic ethanol exposure potentiates lipopolysaccharide liver injury despite inhibiting Jun N-terminal kinase and caspase 3 activation.
-
Chronic ethanol treatment increases expression of inhibitory G-proteins and reduces adenylylcyclase activity in the central nervous system of two lines of ethanol-sensitive mice.
-
Chronic hepcidin induction causes hyposideremia and alters the pattern of cellular iron accumulation in hemochromatotic mice.
-
Chronic high-fat diet decreased detrusor mitochondrial respiration and increased nerve-mediated contractions.
-
Chronic in vivo multi-circuit neurophysiological recordings in mice.
-
Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy.
-
Chronic intermittent hypoxia induces NMDA receptor-dependent plasticity and suppresses nitric oxide signaling in the mouse hypothalamic paraventricular nucleus.
-
Chronic liver disease and impaired hepatic glycogen metabolism in argininosuccinate lyase deficiency.
-
Chronic loss of inhibition in piriform cortex following brief, daily optogenetic stimulation.
-
Chronic loss of noradrenergic tone produces β-arrestin2-mediated cocaine hypersensitivity and alters cellular D2 responses in the nucleus accumbens.
-
Chronic lymphocytic leukemia and regulatory B cells share IL-10 competence and immunosuppressive function.
-
Chronic oxidative stress promotes GADD34-mediated phosphorylation of the TAR DNA-binding protein TDP-43, a modification linked to neurodegeneration.
-
Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathy.
-
Chronic rejection of mouse kidney allografts.
-
Chronic suppression of heart-failure progression by a pseudophosphorylated mutant of phospholamban via in vivo cardiac rAAV gene delivery.
-
Chronic treatment in vivo with β-adrenoceptor agonists induces dysfunction of airway β(2) -adrenoceptors and exacerbates lung inflammation in mice.
-
Chronic wound repair and healing in older adults: current status and future research.
-
Chronopharmacology of strychnine and allylglycine in the mouse.
-
Cigarette smoke-related hydroquinone induces filamentous actin reorganization and heat shock protein 27 phosphorylation through p38 and extracellular signal-regulated kinase 1/2 in retinal pigment epithelium: implications for age-related macular degeneration.
-
Cigarette smoke-related oxidants and the development of sub-RPE deposits in an experimental animal model of dry AMD.
-
Cilia loss sensitizes cells to transformation by activating the mevalonate pathway.
-
Ciliary neurotrophic factor receptor alpha mRNA in NB41A3 neuroblastoma cells: regulation by cAMP.
-
Ciliated epithelial cell lifespan in the mouse trachea and lung.
-
Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice.
-
Circadian rhythms of activity and drinking in mice lacking angiotensin II 1A receptors.
-
Circuit and synaptic organization of forebrain-to-midbrain pathways that promote and suppress vocalization.
-
Circuit-selective striatal synaptic dysfunction in the Sapap3 knockout mouse model of obsessive-compulsive disorder.
-
Circular RNA circEsyt2 regulates vascular smooth muscle cell remodeling via splicing regulation.
-
Circular RNAs are abundant, conserved, and associated with ALU repeats.
-
Circular transcripts of the testis-determining gene Sry in adult mouse testis.
-
Circulating Exosomes Induced by Cardiac Pressure Overload Contain Functional Angiotensin II Type 1 Receptors.
-
Circulating Levels of Soluble Dipeptidyl Peptidase-4 Are Dissociated from Inflammation and Induced by Enzymatic DPP4 Inhibition.
-
Circulating and binding characteristics of wild-type factor IX and certain Gla domain mutants in vivo.
-
Circulating mitochondria in organ donors promote allograft rejection.
-
Circulating tumor cells exit circulation while maintaining multicellularity, augmenting metastatic potential.
-
Circumventing tamoxifen resistance in breast cancers using antiestrogens that induce unique conformational changes in the estrogen receptor.
-
Cis-acting human ApoE tissue expression element is associated with human pattern of intraneuronal ApoE in transgenic mice.
-
Cisplatin, BCNU, cyclophosphamide, and prednisone in multiple myeloma.
-
Citrullination of fibronectin alters integrin clustering and focal adhesion stability promoting stromal cell invasion.
-
Cl- and K+ transport in human biliary cell lines.
-
Class I restricted CTL recognition of a soluble protein delivered by liposomes containing lipophilic polylysines.
-
Class IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactin.
-
Classical Dendritic Cells Mediate Hypertension by Promoting Renal Oxidative Stress and Fluid Retention.
-
Classical conditioning drives learned reward prediction signals in climbing fibers across the lateral cerebellum.
-
Classically conditioned enhancement of hyperinsulinemia in the ob/ob mouse.
-
Classically conditioned hyperglycemia in the obese mouse.
-
Clearance and binding of native and defucosylated lactoferrin.
-
Clearance and binding of two electrophoretic "fast" forms of human alpha 2-macroglobulin.
-
Clearance and distribution of recombinant murine gamma-interferon in mice.
-
Clinical and serologic manifestations of autoimmune disease in MRL-lpr/lpr mice lacking nitric oxide synthase type 2.
-
Clinical isolates of measles virus use CD46 as a cellular receptor.
-
Clinical prospects for neural grafting therapy for hippocampal lesions and epilepsy.
-
Clinical-pathological correlations of BAV and the attendant thoracic aortopathies. Part 2: Pluridisciplinary perspective on their genetic and molecular origins.
-
Clonal Analysis of the Neonatal Mouse Heart using Nearest Neighbor Modeling.
-
Clonal contributions of small numbers of retrovirally marked hematopoietic stem cells engrafted in unirradiated neonatal W/Wv mice.
-
Clonal deletion and clonal anergy in the thymus induced by cellular elements with different radiation sensitivities.
-
Clonal haematopoiesis and risk of chronic liver disease.
-
Cloned endothelium derived from autoimmune vascular disease retain structural and functional characteristics of normal endothelial cells.
-
Cloned mice have an obese phenotype not transmitted to their offspring.
-
Cloning and characterization of ATRAP, a novel protein that interacts with the angiotensin II type 1 receptor.
-
Cloning and characterization of SLP3: a novel member of the stomatin family expressed by olfactory receptor neurons.
-
Cloning and characterization of a cAMP-specific cyclic nucleotide phosphodiesterase.
-
Cloning and characterization of a mammalian lithium-sensitive bisphosphate 3'-nucleotidase inhibited by inositol 1,4-bisphosphate.
-
Cloning and characterization of developmental endothelial locus-1: an embryonic endothelial cell protein that binds the alphavbeta3 integrin receptor.
-
Cloning and characterization of three new murine genes encoding short homologues of RNase P RNA.
-
Cloning and characterization of two human VIP1-like inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinases.
-
Cloning genes that encode inducible forms of P-450.
-
Cloning of B cells from autoimmune MRL-lpr/lpr and MRL.xid mice.
-
Cloning of a complementary DNA encoding a new mouse B lymphocyte differentiation antigen, homologous to the human B1 (CD20) antigen, and localization of the gene to chromosome 19.
-
Cloning of cDNA and analysis of the gene for mouse angiotensin II type 2 receptor.
-
Cloning of human and mouse brain cDNAs coding for S1, the second member of the mammalian elongation factor-1 alpha gene family: analysis of a possible evolutionary pathway.
-
Cloning of mitogen- and antigen-reactive B lymphocytes on filter paper discs. I. A description of the technique and of methods for the analysis of colonies.
-
Cloning of mitogen- and antigen-reactive B lymphocytes on filter paper discs. II. Paratope frequencies within the mitogen-selected repertoire.
-
Cloning of mitogen- and antigen-reactive B lymphocytes on filter paper disks: phenotypic and genotypic analysis of B cell colonies.
-
Cloning of murine splenic T lymphocytes and natural killer (NK) cells on filter paper discs: detection of a novel NK/T phenotype.
-
Cloning of rat thymic stromal lymphopoietin receptor (TSLPR) and characterization of genomic structure of murine Tslpr gene.
-
Cloning, characterization, and chromosomal localization of rec1.3, a member of the G-protein-coupled receptor family highly expressed in brain.
-
Cloning, characterization, and expression of two angiotensin receptor (AT-1) isoforms from the mouse genome.
-
Cloning, expression, and chromosomal localization of beta-adrenergic receptor kinase 2. A new member of the receptor kinase family.
-
Cloning, heterologous expression, and chromosomal localization of human inositol polyphosphate 1-phosphatase.
-
Close genetic and physical linkage between the murine haemopoietic growth factor genes GM-CSF and Multi-CSF (IL3).
-
Closing the iron gate.
-
Club cells surviving influenza A virus infection induce temporary nonspecific antiviral immunity.
-
Clustered Arg–Gly–Asp peptides enhances tumor targeting of nonviral vectors
-
Clustered cancer cells show a distinct adhesion behavior from single cell form under physiological shear conditions.
-
Clustered charged amino acids of human adenosine deaminase comprise a functional epitope for binding the adenosine deaminase complexing protein CD26/dipeptidyl peptidase IV.
-
Clustering of voltage-sensitive sodium channels on axons is independent of direct Schwann cell contact in the dystrophic mouse.
-
Cnksr2 Loss in Mice Leads to Increased Neural Activity and Behavioral Phenotypes of Epilepsy-Aphasia Syndrome.
-
Co-Clinical Imaging Metadata Information (CIMI) for Cancer Research to Promote Open Science, Standardization, and Reproducibility in Preclinical Imaging.
-
Co-assembling peptides as defined matrices for endothelial cells.
-
Co-clinical trials demonstrate superiority of crizotinib to chemotherapy in ALK-rearranged non-small cell lung cancer and predict strategies to overcome resistance.
-
Co-delivery of antigen and IL-12 by Venezuelan equine encephalitis virus replicon particles enhances antigen-specific immune responses and antitumor effects.
-
Co-expression of vimentin and cytokeratins in parietal endoderm cells of early mouse embryo.
-
Co-immunization with multimeric scaffolds and DNA rapidly induces potent autologous HIV-1 neutralizing antibodies and CD8+ T cells.
-
Co-opted JNK/SAPK signaling in Wnt/beta-catenin-induced tumorigenesis.
-
Co-regulation of nuclear respiratory factor-1 by NFkappaB and CREB links LPS-induced inflammation to mitochondrial biogenesis.
-
Coactivation of NF-κB and Notch signaling is sufficient to induce B-cell transformation and enables B-myeloid conversion.
-
Coactivation of liver receptor homologue-1 by peroxisome proliferator-activated receptor gamma coactivator-1alpha on aromatase promoter II and its inhibition by activated retinoid X receptor suggest a novel target for breast-specific antiestrogen therapy.
-
Coactivator PRIP, the peroxisome proliferator-activated receptor-interacting protein, is a modulator of placental, cardiac, hepatic, and embryonic development.
-
Coadministration of IL-12 or IL-10 expression cassettes drives immune responses toward a Th1 phenotype.
-
Coagulation defects and altered hemodynamic responses in mice lacking receptors for thromboxane A2.
-
Cocaine alters Homer1 natural antisense transcript in the nucleus accumbens.
-
Cocaine increases dopamine release by mobilization of a synapsin-dependent reserve pool.
-
Cocaine self-administration reduces excitatory responses in the mouse nucleus accumbens shell.
-
Codon usage optimization of HIV type 1 subtype C gag, pol, env, and nef genes: in vitro expression and immune responses in DNA-vaccinated mice.
-
Coevolution of Adeno-associated Virus Capsid Antigenicity and Tropism through a Structure-Guided Approach.
-
Coevolution of the major histocompatibility complex and the t-complex in the mouse. I. Generation and maintenance of high complementarity associations.
-
Coevolution of the major histocompatibility complex and the t-complex in the mouse. II. Modification of response to sharing of histocompatibility antigens.
-
Cold Plasma Discharge Tube Enhances Antitumoral Efficacy of Temozolomide.
-
Cold-induced brain edema in mice. Involvement of extracellular superoxide dismutase and nitric oxide.
-
Collaborative interactions between MEF-2 and Sp1 in muscle-specific gene regulation.
-
Collagen fibril diameters in arteries of mice. A comparison of manual and computer-aided morphometric analyses.
-
Collagen type-V is a danger signal associated with primary graft dysfunction in lung transplantation.
-
Collagenase 1 and collagenase 3 expression in a guinea pig model of osteoarthritis.
-
Collapsing glomerulopathy: an inflammatory podocytopathy?
-
Colloidal gold fluorescent microspheres: a new retrograde marker visualized by light and electron microscopy.
-
Colonial morphology of staphylococci on Memphis agar: phase variation of slime production, resistance to beta-lactam antibiotics, and virulence.
-
Colonoscopic injection for murine solid cecal cancer model.
-
Colonoscopy-based colorectal cancer modeling in mice with CRISPR-Cas9 genome editing and organoid transplantation.
-
Colorectal cancer models for novel drug discovery.
-
Combination PI3K/MEK inhibition promotes tumor apoptosis and regression in PIK3CA wild-type, KRAS mutant colorectal cancer.
-
Combination anti-CD2 and anti-CD3 monoclonal antibodies induce tolerance while altering interleukin-2, interleukin-4, tumor necrosis factor, and transforming growth factor-beta production.
-
Combination gene therapy for liver metastasis of colon carcinoma in vivo.
-
Combination immunotherapy and radiotherapy causes an abscopal treatment response in a mouse model of castration resistant prostate cancer.
-
Combination induction therapy with monoclonal antibodies specific for CD80, CD86, and CD154 in nonhuman primate renal transplantation.
-
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer.
-
Combination of Rad001 (everolimus) and propachlor synergistically induces apoptosis through enhanced autophagy in prostate cancer cells.
-
Combination of a novel heat shock protein 90-targeted photodynamic therapy with PD-1/PD-L1 blockade induces potent systemic antitumor efficacy and abscopal effect against breast cancers.
-
Combination of ultrasound-based mechanical disruption of tumor with immune checkpoint blockade modifies tumor microenvironment and augments systemic antitumor immunity.
-
Combination testing (Stage 2) of the Anti-IGF-1 receptor antibody IMC-A12 with rapamycin by the pediatric preclinical testing program.
-
Combination testing of cediranib (AZD2171) against childhood cancer models by the pediatric preclinical testing program.
-
Combination therapy of inhibitors of epidermal growth factor receptor/vascular endothelial growth factor receptor 2 (AEE788) and the mammalian target of rapamycin (RAD001) offers improved glioblastoma tumor growth inhibition.
-
Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma.
-
Combination treatment of murine tumors by adenovirus-mediated local B7/IL12 immunotherapy and radiotherapy.
-
Combination versus single agent therapy in effecting complete therapeutic response in human bladder cancer: analysis of cisplatin and/or 5-fluorouracil in an in vivo survival model.
-
Combinatorial Single-Cell Analyses of Granulocyte-Monocyte Progenitor Heterogeneity Reveals an Early Uni-potent Neutrophil Progenitor.
-
Combinatorial depletions of G-protein coupled receptor kinases in immune cells identify pleiotropic and cell type-specific functions.
-
Combined Atomic Force Microscope and Volumetric Light Sheet System for Correlative Force and Fluorescence Mechanobiology Studies.
-
Combined EGFR/MET or EGFR/HSP90 inhibition is effective in the treatment of lung cancers codriven by mutant EGFR containing T790M and MET.
-
Combined MEK and JAK inhibition abrogates murine myeloproliferative neoplasm.
-
Combined Supplementation with Vitamin B-6 and Curcumin is Superior to Either Agent Alone in Suppressing Obesity-Promoted Colorectal Tumorigenesis in Mice.
-
Combined activity of amphotericin B and 5-fluorocytosine against Cryptococcus neoformans in vitro and in vivo in mice.
-
Combined aerobic exercise and enzyme replacement therapy rejuvenates the mitochondrial-lysosomal axis and alleviates autophagic blockage in Pompe disease.
-
Combined bone morphogenetic protein-2 and -7 gene transfer enhances osteoblastic differentiation and spine fusion in a rodent model.
-
Combined deletion of Glut1 and Glut3 impairs lung adenocarcinoma growth.
-
Combined deletion of Id2 and Id3 genes reveals multiple roles for E proteins in invariant NKT cell development and expansion.
-
Combined hyperspectral and spectral domain optical coherence tomography microscope for noninvasive hemodynamic imaging.
-
Combined iDISCO and CUBIC tissue clearing and lightsheet microscopy for in toto analysis of the adult mouse ovary†.
-
Combined kinase inhibitors of MEK1/2 and either PI3K or PDGFR are efficacious in intracranial triple-negative breast cancer.
-
Combined loss of neuronal and endothelial nitric oxide synthase causes premature mortality and age-related hypertrophic cardiac remodeling in mice.
-
Commensal Bacteria Regulate Gene Expression and Differentiation in Vertebrate Olfactory Systems Through Transcription Factor REST.
-
Comments about Joint Modeling of Cluster Size and Binary and Continuous Subunit-Specific Outcomes.
-
Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Activated intrarenal renin-angiotensin system is correlated with high blood pressure in humans.
-
Commissioning a small-field biological irradiator using point, 2D, and 3D dosimetry techniques.
-
Commitment to cell death is signaled by the appearance of a terminin protein of 30 kDa.
-
Common commercial and consumer products contain activators of the aryl hydrocarbon (dioxin) receptor.
-
Common human ANK2 variant confers in vivo arrhythmia phenotypes.
-
Common promoter elements in odorant and vomeronasal receptor genes.
-
Common tolerance mechanisms, but distinct cross-reactivities associated with gp41 and lipids, limit production of HIV-1 broad neutralizing antibodies 2F5 and 4E10.
-
Comparative Analysis of Protein Folding Stability-Based Profiling Methods for Characterization of Biological Phenotypes.
-
Comparative Genomic Analysis of the Pheromone Receptor Class 1 Family (V1R) Reveals Extreme Complexity in Mouse Lemurs (Genus, Microcebus) and a Chromosomal Hotspot across Mammals.
-
Comparative analysis of antigen loading strategies of dendritic cells for tumor immunotherapy.
-
Comparative analysis of the zeta-crystallin/quinone reductase gene in guinea pig and mouse.
-
Comparative and functional evaluation of in vitro generated to ex vivo CD8 T cells.
-
Comparative cellular analysis of motor cortex in human, marmoset and mouse.
-
Comparative effects of thermosensitive doxorubicin-containing liposomes and hyperthermia in human and murine tumours.
-
Comparative evaluation of a new magnetic bead-based DNA extraction method from fecal samples for downstream next-generation 16S rRNA gene sequencing.
-
Comparative genomics search for losses of long-established genes on the human lineage.
-
Comparative immunogenicity of HIV-1 gp160, gp140 and gp120 expressed by live attenuated newcastle disease virus vector.
-
Comparative incorporation of P32 into lung phosphatidyl choline in mammals with different metabolic and pulmonary morphologic characteristics.
-
Comparative localization of glioma-reactive monoclonal antibodies in vivo in an athymic mouse human glioma xenograft model.
-
Comparative localization of murine monoclonal antibody Me1-14 F(ab')2 fragment and whole IgG2a in human glioma xenografts.
-
Comparative pathogenesis of clinical and nonclinical isolates of Saccharomyces cerevisiae.
-
Comparative physical and transcript maps of approximately 1 Mb around loop-tail, a gene for severe neural tube defects on distal mouse chromosome 1 and human chromosome 1q22-q23.
-
Comparative stereology of mouse atria.
-
Comparative stereology of the lizard and frog myocardium.
-
Comparative stereology of the mouse and finch left ventricle.
-
Comparative tissue distribution in mice of the alpha-emitter 211At and 131I as labels of a monoclonal antibody and F(ab')2 fragment.
-
Comparative toxicity of C60 aggregates toward mammalian cells: role of tetrahydrofuran (THF) decomposition.
-
Comparative vibration levels perceived among species in a laboratory animal facility.
-
Comparing human pancreatic cell secretomes by in vitro aptamer selection identifies cyclophilin B as a candidate pancreatic cancer biomarker.
-
Comparing in vivo pump-probe and multiphoton fluorescence microscopy of melanoma and pigmented lesions.
-
Comparison between midline and lateral fluid percussion injury in mice reveals prolonged but divergent cortical neuroinflammation.
-
Comparison of 4D-microSPECT and microCT for murine cardiac function.
-
Comparison of Gene Delivery to the Kidney by Adenovirus, Adeno-Associated Virus, and Lentiviral Vectors After Intravenous and Direct Kidney Injections.
-
Comparison of [18 F]fluorocholine and [18 F]fluorodeoxyglucose for positron emission tomography of androgen dependent and androgen independent prostate cancer.
-
Comparison of animal models for head and neck cancer cachexia.
-
Comparison of fecal biota from specific pathogen free and feral mice.
-
Comparison of in vitro and in vivo differentiation of myeloblastic leukemia of the RFM/Un mouse.
-
Comparison of in vivo efficacy and mechanism of action of antimurine monoclonal antibodies directed against TCR alpha beta (H57-597) and CD3 (145-2C11).
-
Comparison of intradermal and intramuscular delivery followed by in vivo electroporation of SIV Env DNA in macaques.
-
Comparison of monoclonal antibody delivery to intracranial glioma xenografts by intravenous and intracarotid administration.
-
Comparison of multiple vaccine vectors in a single heterologous prime-boost trial.
-
Comparison of pleural responses of rats and hamsters to subchronic inhalation of refractory ceramic fibers.
-
Comparison of the Hypoxia PET Tracer (18)F-EF5 to Immunohistochemical Marker EF5 in 3 Different Human Tumor Xenograft Models.
-
Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm.
-
Comparison of the effects of IL-1 alpha and TNF-alpha on phagocyte accumulation and murine antibacterial immunity.
-
Comparison of the effects of hydralazine on tumor and normal tissue blood perfusion by MRI.
-
Comparison of the expression of three highly related genes, Fgf8, Fgf17 and Fgf18, in the mouse embryo.
-
Comparison of the genomes of the wild-type French viscerotropic strain of yellow fever virus with its vaccine derivative French neurotropic vaccine.
-
Comparison of the role of esterases in the differential age-related sensitivity to chlorpyrifos and methamidophos.
-
Comparison of the roles of calcineurin in physiology and virulence in serotype D and serotype A strains of Cryptococcus neoformans.
-
Comparison of thymocyte development and cytokine production in CD7-deficient, CD28-deficient and CD7/CD28 double-deficient mice.
-
Comparison of tumor and normal tissue oxygen tension measurements using OxyLite or microelectrodes in rodents.
-
Compensatory T cell responses in IRG-deficient mice prevent sustained Chlamydia trachomatis infections.
-
Compensatory hypertrophy induced by ventricular cardiomyocyte-specific COX-2 expression in mice.
-
Compensatory renal growth after unilateral ureteral obstruction.
-
Competing Actions of Type 1 Angiotensin II Receptors Expressed on T Lymphocytes and Kidney Epithelium during Cisplatin-Induced AKI.
-
Competitive displacement of phosphoinositide 3-kinase from beta-adrenergic receptor kinase-1 improves postinfarction adverse myocardial remodeling.
-
Complement C4 inhibits systemic autoimmunity through a mechanism independent of complement receptors CR1 and CR2.
-
Complement Factor H Inhibits CD47-Mediated Resolution of Inflammation.
-
Complement activation contributes to perioperative neurocognitive disorders in mice.
-
Complement and CD4+ T cells drive context-specific corneal sensory neuropathy.
-
Complement component C3d-antigen complexes can either augment or inhibit B lymphocyte activation and humoral immunity in mice depending on the degree of CD21/CD19 complex engagement.
-
Complement receptors CD21/35 link innate and protective immunity during Streptococcus pneumoniae infection by regulating IgG3 antibody responses.
-
Complement-Dependent Synaptic Uptake and Cognitive Decline after Stroke and Reperfusion Therapy.
-
Complementary Roles of GADD34- and CReP-Containing Eukaryotic Initiation Factor 2α Phosphatases during the Unfolded Protein Response.
-
Complementary codes for odor identity and intensity in olfactory cortex.
-
Complementary roles for CD19 and Bruton's tyrosine kinase in B lymphocyte signal transduction.
-
Complete and unidirectional conversion of human embryonic stem cells to trophoblast by BMP4.
-
Complete correction of hyperphenylalaninemia following liver-directed, recombinant AAV2/8 vector-mediated gene therapy in murine phenylketonuria.
-
Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV.
-
Complex Antigens Drive Permissive Clonal Selection in Germinal Centers.
-
Complex Role for E-Prostanoid 4 Receptors in Hypertension.
-
Complexes between serpins and inactive proteinases are not thermodynamically stable but are recognized by serpin receptors.
-
Complexity of CNC transcription factors as revealed by gene targeting of the Nrf3 locus.
-
Components of a new gene family of ferroxidases involved in virulence are functionally specialized in fungal dimorphism.
-
Compound haploinsufficiency of Dok2 and Dusp4 promotes lung tumorigenesis.
-
Compounds from Sichuan and Melegueta peppers activate, covalently and non-covalently, TRPA1 and TRPV1 channels.
-
Comprehensive analysis of commercially available mouse antichicken monoclonal antibodies for cross-reactivity with peripheral blood leukocytes from commercial turkeys.
-
Comprehensive characterization and optimization of anti-LRRK2 (leucine-rich repeat kinase 2) monoclonal antibodies.
-
Comprehensive metabolic modeling of multiple 13C-isotopomer data sets to study metabolism in perfused working hearts.
-
Comprehensive pharmacokinetic studies and oral bioavailability of two Mn porphyrin-based SOD mimics, MnTE-2-PyP5+ and MnTnHex-2-PyP5+.
-
Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition.
-
Compromised HOXA5 function can limit p53 expression in human breast tumours.
-
Computational and experimental analyses reveal previously undetected coding exons of the KRIT1 (CCM1) gene.
-
Computational modelling of perivascular-niche dynamics for the optimization of treatment schedules for glioblastoma.
-
Computational models of cancer cell transport through the microcirculation.
-
Computational multiscale toxicodynamic modeling of silver and carbon nanoparticle effects on mouse lung function.
-
Computational tools for understanding sequence variability in recombination signals.
-
Computed tomography imaging of primary lung cancer in mice using a liposomal-iodinated contrast agent.
-
Computer-aided Discovery of a New Nav1.7 Inhibitor for Treatment of Pain and Itch.
-
Computer-aided Discovery of a New Nav1.7 Inhibitor for Treatment of Pain and Itch.
-
Comt1 genotype and expression predicts anxiety and nociceptive sensitivity in inbred strains of mice.
-
Concentrated RD114-pseudotyped MFGS-gp91phox vector achieves high levels of functional correction of the chronic granulomatous disease oxidase defect in NOD/SCID/beta -microglobulin-/- repopulating mobilized human peripheral blood CD34+ cells.
-
Concerted morphogenesis of genital ridges and nephric ducts in the mouse captured through whole-embryo imaging.
-
Concerted regulation of skeletal muscle contractility by oxygen tension and endogenous nitric oxide.
-
Concomitant BRAF and PI3K/mTOR blockade is required for effective treatment of BRAF(V600E) colorectal cancer.
-
Concomitant control of mechanical properties and degradation in resorbable elastomer-like materials using stereochemistry and stoichiometry for soft tissue engineering.
-
Concurrent PEDF deficiency and Kras mutation induce invasive pancreatic cancer and adipose-rich stroma in mice.
-
Concurrent administration of coenzyme Q10 and alpha-tocopherol improves learning in aged mice.
-
Concurrent production of reactive oxygen and nitrogen species by airway epithelial cells in vitro.
-
Conditional HIF-1 induction produces multistage neovascularization with stage-specific sensitivity to VEGFR inhibitors and myeloid cell independence.
-
Conditional Macrophage Depletion Increases Inflammation and Does Not Inhibit the Development of Osteoarthritis in Obese Macrophage Fas-Induced Apoptosis-Transgenic Mice.
-
Conditional Silencing of H-2Db Class I Molecule Expression Modulates the Protective and Pathogenic Kinetics of Virus-Antigen-Specific CD8 T Cell Responses during Theiler's Virus Infection.
-
Conditional antibody expression to avoid central B cell deletion in humanized HIV-1 vaccine mouse models.
-
Conditional deletion of TrkB but not BDNF prevents epileptogenesis in the kindling model.
-
Conditional deletion of TrkC does not modify limbic epileptogenesis.
-
Conditional expression in corticothalamic efferents reveals a developmental role for nicotinic acetylcholine receptors in modulation of passive avoidance behavior.
-
Conditional expression of SV40 T-antigen in mouse cardiomyocytes facilitates an inducible switch from proliferation to differentiation.
-
Conditional expression of the mutant Ki-rasG12C allele results in formation of benign lung adenomas: development of a novel mouse lung tumor model.
-
Conditional gene silencing in mammalian cells mediated by a stress-inducible promoter.
-
Conditional knockout of Fgf13 in murine hearts increases arrhythmia susceptibility and reveals novel ion channel modulatory roles.
-
Conditional targeting of E-cadherin in skin: insights into hyperproliferative and degenerative responses.
-
Conditional telomerase induction causes proliferation of hair follicle stem cells.
-
Conditions for an in vitro culture of murine mixed hematopoietic colonies and their putative cellular origin.
-
Conditions that promote primary human skeletal myoblast culture and muscle differentiation in vitro.
-
Conformable hierarchically engineered polymeric micromeshes enabling combinatorial therapies in brain tumours.
-
Conformational considerations in the design of dual antagonists of platelet-activating factor (PAF) and histamine.
-
Congenital neuro-ophthalmic toxoplasmosis in the mouse.
-
Congenital polycystic kidney disease. Genetically transmitted infantile polycystic kidney disease in C57BL/6J mice.
-
Congenital toxoplasmic retinochoroiditis in a mouse model.
-
Conjugate of Doxorubicin to Albumin-Binding Peptide Outperforms Aldoxorubicin.
-
Connectome Smoothing via Low-Rank Approximations.
-
Connexin 36 and rod bipolar cell independent rod pathways drive retinal ganglion cells and optokinetic reflexes.
-
Connexin-43 induces chemokine release from spinal cord astrocytes to maintain late-phase neuropathic pain in mice.
-
Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms.
-
Consensus report of the national cancer institute clinical trials planning meeting on pancreas cancer treatment.
-
Consequences of intra-articular bleeding in haemophilia: science to clinical practice and beyond.
-
Conservation of dishevelled structure and function between flies and mice: isolation and characterization of Dvl2.
-
Conserved Residues Control Activation of Mammalian G Protein-Coupled Odorant Receptors.
-
Conserved action of β-catenin during female fate determination in the red-eared slider turtle.
-
Conserved and divergent expression dynamics during early patterning of the telencephalon in mouse and chick embryos.
-
Conserved cryptic recombination signals in Vkappa gene segments are cleaved in small pre-B cells.
-
Constitutive Notch signalling promotes CD4 CD8 thymocyte differentiation in the absence of the pre-TCR complex, by mimicking pre-TCR signals.
-
Constitutive Stat3 activation alters behavior of hair follicle stem and progenitor cell populations.
-
Constitutive activation of NOTCH1 signaling in Sertoli cells causes gonocyte exit from quiescence.
-
Constitutive activation of the aromatic hydrocarbon receptor.
-
Constitutive and inducible interleukin 8 expression by hypoxia and acidosis renders human pancreatic cancer cells more tumorigenic and metastatic.
-
Constitutive hedgehog signaling in chondrosarcoma up-regulates tumor cell proliferation.
-
Constitutive hepcidin expression prevents iron overload in a mouse model of hemochromatosis.
-
Constitutive proteasome-mediated turnover of Bfl-1/A1 and its processing in response to TNF receptor activation in FL5.12 pro-B cells convert it into a prodeath factor.
-
Constitutively activated STAT3 frequently coexpresses with epidermal growth factor receptor in high-grade gliomas and targeting STAT3 sensitizes them to Iressa and alkylators.
-
Constructing an adult orofacial premotor atlas in Allen mouse CCF.
-
Construction and preclinical characterization of Fc-mGITRL for the immunotherapy of cancer.
-
Construction of a global pain systems network highlights phospholipid signaling as a regulator of heat nociception.
-
Construction of low-variability litters of preweaning mice.
-
Construction of modular circuits in the mammalian brain.
-
Construction, imaging, and analysis of FRET-based tension sensors in living cells.
-
Contained indirect viable-cell membrane immunofluorescence microassay for surface antigen analysis of cells infected with hazardous viruses.
-
Contamination with E1A-positive wild-type adenovirus accounts for species-specific stimulation of islet cell proliferation by CCK: a cautionary note.
-
Content and Performance of the MiniMUGA Genotyping Array: A New Tool To Improve Rigor and Reproducibility in Mouse Research.
-
Context-dependent effects of whole-genome duplication during mammary tumor recurrence.
-
Context-specific effects of fibulin-5 (DANCE/EVEC) on cell proliferation, motility, and invasion. Fibulin-5 is induced by transforming growth factor-beta and affects protein kinase cascades.
-
Continuous Culture of Mouse Primary B Lymphocytes by Forced Expression of Bach2.
-
Continuous Hypoxia Reduces Retinal Ganglion Cell Degeneration in a Mouse Model of Mitochondrial Optic Neuropathy.
-
Continuous administration of the three thrombospondin-1 type 1 repeats recombinant protein improves the potency of therapy in an orthotopic human pancreatic cancer model.
-
Contrast dependence and differential contributions from somatostatin- and parvalbumin-expressing neurons to spatial integration in mouse V1.
-
Contrast-enhanced in vivo magnetic resonance microscopy of the mouse brain enabled by noninvasive opening of the blood-brain barrier with ultrasound.
-
Contrasting response of lung parenchymal cells to instilled TNF alpha and IFN gamma: the inducibility of specific cell ICAM-1 in vivo.
-
Contribution of 3CD Region to the Virulence of Enterovirus 71.
-
Contribution of IL-13 to early exocrinopathy in Id3-/- mice.
-
Contribution of Polycomb group proteins to olfactory basal stem cell self-renewal in a novel c-KIT+ culture model and in vivo.
-
Contribution of Sensory Encoding to Measured Bias.
-
Contribution of a 28-kilodalton membrane protein to the virulence of Haemophilus influenzae.
-
Contribution of adipogenesis to healthy adipose tissue expansion in obesity.
-
Contribution of mast cells to bacterial clearance and their proliferation during experimental cystitis induced by type 1 fimbriated E. coli.
-
Contribution of platelets, the coagulation and fibrinolytic systems to cutaneous wound healing.
-
Contribution of the VH11 gene family to mitogen-responsive B cell repertoire in C57BL/6 mice.
-
Contributions of CD8 T cells to the pathogenesis of mouse adenovirus type 1 respiratory infection.
-
Contributions of E1A to mouse adenovirus type 1 pathogenesis following intranasal inoculation.
-
Contributions of beta2-microglobulin-dependent molecules and lymphocytes to iron regulation: insights from HfeRag1(-/-) and beta2mRag1(-/-) double knock-out mice.
-
Contributions of endothelial and neuronal nitric oxide synthases to cerebrovascular responses to hyperoxia.
-
Contributions of mast cells and vasoactive products, leukotrienes and chymase, to dengue virus-induced vascular leakage.
-
Contributions of nitric oxide synthase isoforms to pulmonary oxygen toxicity, local vs. mediated effects.
-
Control elements within the PWS/AS imprinting box and their function in the imprinting process.
-
Control idiotope expression by monoclonal anti-idiotope antibodies.
-
Control of CD4 gene expression: connecting signals to outcomes in T cell development.
-
Control of IFN-gamma-mediated host resistance to intracellular pathogens by immunity-related GTPases (p47 GTPases).
-
Control of Intestinal Inflammation, Colitis-Associated Tumorigenesis, and Macrophage Polarization by Fibrinogen-Like Protein 2.
-
Control of PD-L1 Expression by Oncogenic Activation of the AKT-mTOR Pathway in Non-Small Cell Lung Cancer.
-
Control of PI(3) kinase in Treg cells maintains homeostasis and lineage stability.
-
Control of RhoA methylation by carboxylesterase I.
-
Control of basement membrane remodeling and epithelial branching morphogenesis in embryonic lung by Rho and cytoskeletal tension.
-
Control of cyclin B1 localization through regulated binding of the nuclear export factor CRM1.
-
Control of embryonic lung branching morphogenesis by the Rho activator, cytotoxic necrotizing factor 1.
-
Control of excitatory CNS synaptogenesis by astrocyte-secreted proteins Hevin and SPARC.
-
Control of expression of insulin resistance and hyperglycemia by different genetic factors in diabetic C57BL/6J mice.
-
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1.
-
Control of idiotope expression by monoclonal anti-idiotope and idiotope-bearing antibody.
-
Control of liver and brain aromatic amino-acid metabolism by phenylalanine hydroxylase.
-
Control of mammalian circadian rhythm by CKIepsilon-regulated proteasome-mediated PER2 degradation.
-
Control of mitotic exit by PP2A regulation of Cdc25C and Cdk1.
-
Control of morphology and virulence by ADP-ribosylation factors (Arf) in Mucor circinelloides.
-
Control of myocardial contractile function by the level of beta-adrenergic receptor kinase 1 in gene-targeted mice.
-
Control of the differentiation of regulatory T cells and T(H)17 cells by the DNA-binding inhibitor Id3.
-
Control of thymic T cell maturation, deletion and egress by the RNA-binding protein HuR.
-
Controlled Lengthwise Assembly of Helical Peptide Nanofibers to Modulate CD8+
T-Cell Responses.
-
Controlled Release of Vancomycin and Tigecycline from an Orthopaedic Implant Coating Prevents Staphylococcus aureus
Infection in an Open Fracture Animal Model.
-
Controlled release of etoricoxib from poly(ester urea) films for post-operative pain management.
-
Controlled release of simvastatin from in situ forming hydrogel triggers bone formation in MC3T3-E1 cells.
-
Controlling cancer-induced inflammation with a nucleic acid scavenger prevents lung metastasis in murine models of breast cancer.
-
Controlling for activity-dependent genes and behavioral states is critical for determining brain relationships within and across species.
-
Convergence of Parkin, PINK1, and α-Synuclein on Stress-induced Mitochondrial Morphological Remodeling.
-
Convergence of bladder and colon sensory innervation occurs at the primary afferent level.
-
Convergence of oncogenic and hormone receptor pathways promotes metastatic phenotypes.
-
Convergence of presenilin- and tau-mediated pathways on axonal trafficking and neuronal function.
-
Convergent and divergent evolution of genomic imprinting in the marsupial Monodelphis domestica.
-
Convergent differential regulation of SLIT-ROBO axon guidance genes in the brains of vocal learners.
-
Convergent effects of mouse Pet-1 deletion and human PET-1 variation on amygdala fear and threat processing.
-
Convergent effects on cell signaling mechanisms mediate the actions of different neurobehavioral teratogens: alterations in cholinergic regulation of protein kinase C in chick and avian models.
-
Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity
-
Conversion of effector CD4+ T cells to a CD8+ MHC II-recognizing lineage.
-
Cooperation among multiple transcription factors is required for access to minimal T-cell receptor alpha-enhancer chromatin in vivo.
-
Cooperation between core binding factor and adjacent promoter elements contributes to the tissue-specific expression of interleukin-3.
-
Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3.
-
Cooperativity between the phosphorylation of Thr95 and Ser77 of NHERF-1 in the hormonal regulation of renal phosphate transport.
-
Coordinate regulation of forskolin-induced cellular proliferation in macrophages by protein kinase A/cAMP-response element-binding protein (CREB) and Epac1-Rap1 signaling: effects of silencing CREB gene expression on Akt activation.
-
Coordinate regulation of mRNAs from multiple calmodulin genes during myoblast differentiation in vitro.
-
Coordinate regulation of the alpha(2)-macroglobulin signaling receptor and the low density lipoprotein receptor-related protein/alpha(2)-macroglobulin receptor by insulin.
-
Coordinated cerebellar climbing fiber activity signals learned sensorimotor predictions.
-
Coordinated genome-wide modifications within proximal promoter cis-regulatory elements during vertebrate evolution
-
Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole.
-
Copper Chelation as Targeted Therapy in a Mouse Model of Oncogenic BRAF-Driven Papillary Thyroid Cancer.
-
Copper is a potent inhibitor of both the canonical and non-canonical NFκB pathways.
-
Copper is required for oncogenic BRAF signalling and tumorigenesis.
-
Cord blood and bone marrow transplantation in inherited metabolic diseases: scientific basis, current status and future directions.
-
Cordon-bleu is a conserved gene involved in neural tube formation.
-
Cordon-bleu is an actin nucleation factor and controls neuronal morphology.
-
Core N-Glycan Structures Are Critical for the Pathogenicity of Cryptococcus neoformans by Modulating Host Cell Death.
-
Coreceptor signal strength regulates positive selection but does not determine CD4/CD8 lineage choice in a physiologic in vivo model.
-
Corneal dystrophy mutations R125H and R804H disable SLC4A11 by altering the extracellular pH dependence of the intracellular pK that governs H+
(OH-
) transport.
-
Corneal penetration of topical and subconjunctival bevacizumab.
-
Corpora amylacea are associated with tau burden and cognitive status in Alzheimer's disease.
-
Correcting the limited view in optical-resolution photoacoustic microscopy.
-
Correction for differences in germ cell stage sensitivity in risk assessment.
-
Correction of aberrant splicing of the cystic fibrosis transmembrane conductance regulator (CFTR) gene by antisense oligonucleotides.
-
Correction of dystrophin expression in cells from Duchenne muscular dystrophy patients through genomic excision of exon 51 by zinc finger nucleases.
-
Correction of glycogen storage disease type II by an adeno-associated virus vector containing a muscle-specific promoter.
-
Correction of multiple striated muscles in murine Pompe disease through adeno-associated virus-mediated gene therapy.
-
Correction of proliferative responses in purine nucleoside phosphorylase (PNP)-deficient T lymphocytes by retroviral-mediated PNP gene transfer and expression.
-
Correction: Mouse Models of Diet-Induced Nonalcoholic Steatohepatitis Reproduce the Heterogeneity of the Human Disease.
-
Correlating notch signaling with thymocyte maturation.
-
Correlation between axonal morphologies and synaptic input kinetics of interneurons from mouse visual cortex.
-
Correlation of DNA fragmentation and chromatin condensation in apoptotic nuclei of the Ser 6 mouse retina.
-
Correlation of expression of bombesin-like peptides and receptors with growth inhibition by an anti-bombesin antibody in small-cell lung cancer cell lines.
-
Correlation of the tight junction-like distribution of Claudin-1 to the cellular tropism of hepatitis C virus.
-
Correlation of total and interstrand DNA adducts in tumor and kidney with antitumor efficacies and differential nephrotoxicities of cis-ammine/cyclohexylamine-dichloroplatinum(II) and cisplatin.
-
Correlative Confocal and 3D Electron Microscopy of a Specific Sensory Cell.
-
Correspondence re: Geradts J, Wilentz RE, Roberts H. Immunohistochemical detection of the alternate ink4a-encoded tumor suppressor protein p14(arf) in archival human cancers and cell lines using commercial antibodies: correlation with p16(ink4a) expression. Mod pathol 2001;14:1162-68.
-
Cortical control of affective networks.
-
Cortical glutamatergic projection neuron types contribute to distinct functional subnetworks.
-
Cortical glutamic acid decarboxylase 67 deficiency results in lower cannabinoid 1 receptor messenger RNA expression: implications for schizophrenia.
-
Cortical inhibition modified by embryonic neural precursors grafted into the postnatal brain.
-
Cortical interneurons that specialize in disinhibitory control.
-
Cortical plasticity induced by inhibitory neuron transplantation.
-
Cortical representations of olfactory input by trans-synaptic tracing.
-
Cortical-amygdalar circuit dysfunction in a genetic mouse model of serotonin deficiency.
-
Cortico-cortical projections in mouse visual cortex are functionally target specific.
-
Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice.
-
Corticorelin acetate, a synthetic corticotropin-releasing factor with preclinical antitumor activity, alone and with bevacizumab, against human brain tumor models.
-
Costimulation Blockade Resistant Rejection.
-
Costimulation of adenylyl cyclase and phospholipase C by a mutant alpha 1B-adrenergic receptor transgene promotes malignant transformation of thyroid follicular cells.
-
Costimulator dependence of lymphokine secretion by naive and activated CD4+ T lymphocytes from TCR transgenic mice.
-
Counteracting signaling activities in lipid rafts associated with the invasion of lung epithelial cells by Pseudomonas aeruginosa.
-
Coupled myovascular expansion directs cardiac growth and regeneration.
-
Coupling of beta2-adrenoceptor to Gi proteins and its physiological relevance in murine cardiac myocytes.
-
Coupling of human DNA excision repair and the DNA damage checkpoint in a defined in vitro system.
-
Covalent complexes of antigen and alpha(2)-macroglobulin: evidence for dramatically-increased immunogenicity.
-
Covalent immobilization of stem cell factor and stromal derived factor 1α for in vitro culture of hematopoietic progenitor cells.
-
Covalently immobilized platelet-derived growth factor-BB promotes angiogenesis in biomimetic poly(ethylene glycol) hydrogels.
-
Cowpox virus genome encodes a second soluble homologue of cellular TNF receptors, distinct from CrmB, that binds TNF but not LT alpha.
-
Cowpox virus induces interleukin-10 both in vitro and in vivo.
-
Coxsackievirus A2 Leads to Heart Injury in a Neonatal Mouse Model.
-
Cp/Heph mutant mice have iron-induced neurodegeneration diminished by deferiprone.
-
Cre-dependent adeno-associated virus preparation and delivery for labeling neurons in the mouse brain.
-
Creatine and cyclocreatine attenuate MPTP neurotoxicity.
-
Creatine kinase activity as an indicator of unopposed estrogen action in the mouse uterus associated with anti-progesterone treatment.
-
Creatine kinase overexpression improves ATP kinetics and contractile function in postischemic myocardium.
-
Creatine kinase-mediated improvement of function in failing mouse hearts provides causal evidence the failing heart is energy starved.
-
Creation of human tumour cells with defined genetic elements.
-
Creation of versatile cloning platforms for transgene expression and dCas9-based epigenome editing.
-
Critical role for mouse marginal zone B cells in PF4/heparin antibody production.
-
Critical role for the alpha-1B adrenergic receptor at the sympathetic neuroeffector junction.
-
Critical role for the chemokine receptor CXCR6 in NK cell-mediated antigen-specific memory of haptens and viruses.
-
Critical role of FoxO3a in alcohol-induced autophagy and hepatotoxicity.
-
Critical role of NOD2 in regulating the immune response to Staphylococcus aureus.
-
Critical role of TNF-α in cerebral aneurysm formation and progression to rupture.
-
Critical role of the tumor suppressor tuberous sclerosis complex 1 in dendritic cell activation of CD4 T cells by promoting MHC class II expression via IRF4 and CIITA.
-
Critical roles of RasGRP1 for invariant NKT cell development.
-
Critical roles of mTOR Complex 1 and 2 for T follicular helper cell differentiation and germinal center responses.
-
Cross species genomic analysis identifies a mouse model as undifferentiated pleomorphic sarcoma/malignant fibrous histiocytoma.
-
Cross-Reactive Immunity Among Flaviviruses.
-
Cross-Reactivity to Kynureninase Tolerizes B Cells That Express the HIV-1 Broadly Neutralizing Antibody 2F5.
-
Cross-reacting antigens on L5178Y cells which serve as targets for cytotoxic T-lymphocyte lysis during establishment of the tumor dormant state.
-
Cross-reactions of virally and chemically induced mouse sarcomas: surface expression of a common viral antigen.
-
Cross-reactive coronavirus antibodies with diverse epitope specificities and Fc effector functions.
-
Cross-reactive monoclonal antibodies to multiple HIV-1 subtype and SIVcpz envelope glycoproteins.
-
Cross-species DNA copy number analyses identifies multiple 1q21-q23 subtype-specific driver genes for breast cancer.
-
Cross-species analysis of genetically engineered mouse models of MAPK-driven colorectal cancer identifies hallmarks of the human disease.
-
Cross-species evolution of a highly potent AAV variant for therapeutic gene transfer and genome editing.
-
Cross-subtype T-cell immune responses induced by a human immunodeficiency virus type 1 group m consensus env immunogen.
-
Cross-talk between Notch and Hedgehog regulates hepatic stellate cell fate in mice.
-
Cross-talk between Schwann cells and neuroblasts influences the biology of neuroblastoma xenografts.
-
Crosslinked hyaluronic acid hydrogels: a strategy to functionalize and pattern
-
Crosstransplantation of kidneys in normal and Hyp mice. Evidence that the Hyp mouse phenotype is unrelated to an intrinsic renal defect.
-
Crucial role for the VWF A1 domain in binding to type IV collagen.
-
Crucial role of copper in detection of metal-coordinating odorants.
-
Cryo-electron microscopy of biological samples.
-
Cryopreservation of neurospheres derived from human glioblastoma multiforme.
-
Cryptococcal cell morphology affects host cell interactions and pathogenicity.
-
Cryptococcal titan cell formation is regulated by G-protein signaling in response to multiple stimuli.
-
Cryptococcosis.
-
Cryptococcus gattii VGIII isolates causing infections in HIV/AIDS patients in Southern California: identification of the local environmental source as arboreal.
-
Cryptococcus neoformans Cda1 and Its Chitin Deacetylase Activity Are Required for Fungal Pathogenesis.
-
Cryptococcus neoformans Chitin Synthase 3 Plays a Critical Role in Dampening Host Inflammatory Responses.
-
Cryptococcus neoformans Ilv2p confers resistance to sulfometuron methyl and is required for survival at 37 degrees C and in vivo.
-
Cryptococcus neoformans Kin1 protein kinase homologue, identified through a Caenorhabditis elegans screen, promotes virulence in mammals.
-
Cryptococcus neoformans Rim101 is associated with cell wall remodeling and evasion of the host immune responses.
-
Cryptococcus neoformans copper detoxification machinery is critical for fungal virulence.
-
Cryptococcus neoformans gene expression during murine macrophage infection.
-
Cryptococcus neoformans gene involved in mammalian pathogenesis identified by a Caenorhabditis elegans progeny-based approach.
-
Cryptococcus neoformans hyperfilamentous strain is hypervirulent in a murine model of cryptococcal meningoencephalitis.
-
Cryptococcus neoformans is resistant to surfactant protein A mediated host defense mechanisms.
-
Cryptococcus neoformans methionine synthase: expression analysis and requirement for virulence.
-
Cryptococcus neoformans mitochondrial superoxide dismutase: an essential link between antioxidant function and high-temperature growth.
-
Cryptococcus neoformans phosphoinositide-dependent kinase 1 (PDK1) ortholog is required for stress tolerance and survival in murine phagocytes.
-
Cryptococcus neoformans requires a functional glycolytic pathway for disease but not persistence in the host.
-
Cryptococcus neoformans resists to drastic conditions by switching to viable but non-culturable cell phenotype.
-
Cryptococcus neoformans {alpha} strains preferentially disseminate to the central nervous system during coinfection.
-
Cryptococcus neoformans: a sugar-coated killer with designer genes.
-
Cryptosporidium-malnutrition interactions: mucosal disruption, cytokines, and TLR signaling in a weaned murine model.
-
Crystal structure of the major histocompatibility complex class I H-2Kb molecule containing a single viral peptide: implications for peptide binding and T-cell receptor recognition.
-
Culture of endodermal stem/progenitor cells of the mouse tongue.
-
Culture-enriched community profiling improves resolution of the vertebrate gut microbiota.
-
Curative Treatment of Severe Gram-Negative Bacterial Infections by a New Class of Antibiotics Targeting LpxC.
-
Curcumin Ameliorates Heat-Induced Injury through NADPH Oxidase-Dependent Redox Signaling and Mitochondrial Preservation in C2C12 Myoblasts and Mouse Skeletal Muscle.
-
Curcumin β-D-Glucuronide Modulates an Autoimmune Model of Multiple Sclerosis with Altered Gut Microbiota in the Ileum and Feces.
-
Curdlan, a Microbial β-Glucan, Has Contrasting Effects on Autoimmune and Viral Models of Multiple Sclerosis.
-
Current knowledge of the platelet glycoprotein IIb/IIIa receptor antagonists for the treatment of coronary artery disease.
-
Cutaneous wound healing is impaired in hemophilia B.
-
Cutaneous wound healing through paradoxical MAPK activation by BRAF inhibitors
-
Cutting Edge: Elevated Glycolytic Metabolism Limits the Formation of Memory CD8+ T Cells in Early Life.
-
Cutting Edge: Localization of linker for activation of T cells to lipid rafts is not essential in T cell activation and development.
-
Cutting Edge: c-Maf Is Required for Regulatory T Cells To Adopt RORγt+ and Follicular Phenotypes.
-
Cutting edge: ABIN-1 protects against psoriasis by restricting MyD88 signals in dendritic cells.
-
Cutting edge: C3d functions as a molecular adjuvant in the absence of CD21/35 expression.
-
Cutting edge: CD91-independent cross-presentation of GRP94(gp96)-associated peptides.
-
Cutting edge: Cytosolic bacterial DNA activates the inflammasome via Aim2.
-
Cutting edge: Mouse NAIP1 detects the type III secretion system needle protein.
-
Cutting edge: RIPK1 Kinase inactive mice are viable and protected from TNF-induced necroptosis in vivo.
-
Cutting edge: Rapamycin augments pathogen-specific but not graft-reactive CD8+ T cell responses.
-
Cutting edge: Role of osteopontin and integrin αv in T cell-mediated anti-inflammatory responses in endotoxemia.
-
Cutting edge: TGF-beta-induced expression of Foxp3 in T cells is mediated through inactivation of ERK.
-
Cutting edge: critical role of intracellular osteopontin in antifungal innate immune responses.
-
Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.
-
Cutting edge: hierarchy of chemokine receptor and TCR signals regulating T cell migration and proliferation.
-
Cutting edge: trimolecular interaction of TCR with MHC class II and bacterial superantigen shows a similar affinity to MHC:peptide ligands.
-
Cybrd1 (duodenal cytochrome b) is not necessary for dietary iron absorption in mice.
-
Cyclic AMP-dependent protein kinase catalytic subunits have divergent roles in virulence factor production in two varieties of the fungal pathogen Cryptococcus neoformans.
-
Cyclic AMP-dependent protein kinase controls virulence of the fungal pathogen Cryptococcus neoformans.
-
Cyclic AMP-regulated exocytosis of Escherichia coli from infected bladder epithelial cells.
-
Cyclic Alopecia and Abnormal Epidermal Cornification in Zdhhc13-Deficient Mice Reveal the Importance of Palmitoylation in Hair and Skin Differentiation.
-
Cyclic Regulation of Sensory Perception by a Female Hormone Alters Behavior.
-
Cyclin D1 inhibits peroxisome proliferator-activated receptor gamma-mediated adipogenesis through histone deacetylase recruitment.
-
Cyclin D1 overexpression and response to bortezomib treatment in a breast cancer model.
-
Cyclin-dependent kinase 4 expression alters the number of keratinocyte stem cells in the mouse hair follicle.
-
Cyclocreatine (1-carboxymethyl-2-iminoimidazolidine) inhibits growth of a broad spectrum of cancer cells derived from solid tumors.
-
Cyclocreatine (1-carboxymethyl-2-iminoimidazolidine) inhibits the replication of human herpes viruses.
-
Cyclooxygenase-1 and -2 knockout mice demonstrate increased cardiac ischemia/reperfusion injury but are protected by acute preconditioning.
-
Cyclooxygenase-2 is a novel transcriptional target of the nuclear EGFR-STAT3 and EGFRvIII-STAT3 signaling axes.
-
Cyclooxygenase-two (COX-2) modulates proliferation in aggressive fibromatosis (desmoid tumor).
-
Cyclophosphamide treatment used to manipulate the immune response for the production of monoclonal antibodies.
-
Cyclosporin A inhibits inositol 1,4,5-trisphosphate binding to its receptors and release of calcium from intracellular stores in peritoneal macrophages.
-
Cyclosporin-A increases synthesis of 1,25-dihydroxyvitamin D3 in the rat and mouse.
-
Cyclosporine inhibition of CH series murine B-cell lymphomas.
-
Cyclosporine inhibition of a murine B cell lymphoma.
-
Cyr61 mediates hepatocyte growth factor-dependent tumor cell growth, migration, and Akt activation.
-
Cysteine 70 of ankyrin-G is S-palmitoylated and is required for function of ankyrin-G in membrane domain assembly.
-
Cysteine-tailed class I-binding peptides bind to CpG adjuvant and enhance primary CTL responses.
-
Cystic fibrosis transmembrane conductance regulator activation is reduced in the small intestine of Na+/H+ exchanger 3 regulatory factor 1 (NHERF-1)- but Not NHERF-2-deficient mice.
-
Cystic fibrosis transmembrane regulator regulates uptake of sphingoid base phosphates and lysophosphatidic acid: modulation of cellular activity of sphingosine 1-phosphate.
-
Cystine Deprivation Triggers Programmed Necrosis in VHL-Deficient Renal Cell Carcinomas.
-
Cytoarchitecture of the mouse brain by high resolution diffusion magnetic resonance imaging.
-
Cytochrome P1-450 structural gene in mouse, rat, and rabbit: differences in DNA methylation and developmental expression of mRNA.
-
Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis.
-
Cytochrome c peroxidase contributes to the antioxidant defense of Cryptococcus neoformans.
-
Cytocidal amino acid starvation of Saccharomyces cerevisiae and Candida albicans acetolactate synthase (ilv2{Delta}) mutants is influenced by the carbon source and rapamycin.
-
Cytogenetic changes induced by 1-(N1-methylhydrazinomethyl)-N-isopropyl benzamide in Ehrlich ascites tumor cells.
-
Cytokine activation of nuclear factor kappa B in vascular smooth muscle cells requires signaling endosomes containing Nox1 and ClC-3.
-
Cytokine deposition alters leukocyte morphology and initial recruitment of monocytes and γδT cells after corneal injury.
-
Cytokine expression by invariant natural killer T cells is tightly regulated throughout development and settings of type-2 inflammation.
-
Cytokine expression in vivo during murine herpetic stromal keratitis. Effect of protective antibody therapy.
-
Cytokine induction of nuclear factor kappa B in cycling and growth-arrested cells. Evidence for cell cycle-independent activation.
-
Cytokine requirements for induction of systemic and mucosal CTL after nasal immunization.
-
Cytokine signals through STAT3 promote expression of granulocyte secondary granule proteins in 32D cells.
-
Cytokine stimulation of aerobic glycolysis in hematopoietic cells exceeds proliferative demand.
-
Cytokine stimulation promotes glucose uptake via phosphatidylinositol-3 kinase/Akt regulation of Glut1 activity and trafficking.
-
Cytokine storm-based mechanisms for extrapulmonary manifestations of SARS-CoV-2 infection.
-
Cytokine transcriptional events during helper T cell subset differentiation.
-
Cytokine-dependent and cytokine-independent roles for Mcl-1: genetic evidence for multiple mechanisms by which Mcl-1 promotes survival in primary T lymphocytes.
-
Cytokines as adjuvants for the induction of anti-human immunodeficiency virus peptide immunoglobulin G (IgG) and IgA antibodies in serum and mucosal secretions after nasal immunization.
-
Cytokines in murine lyme carditis: Th1 cytokine expression follows expression of proinflammatory cytokines in a susceptible mouse strain.
-
Cytomegalovirus as an immunomodulator across the lifespan.
-
Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock.
-
Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf.
-
Cytoplasmic polyadenylation element binding protein deficiency stimulates PTEN and Stat3 mRNA translation and induces hepatic insulin resistance.
-
Cytoprotection by somatostatin of normal and malignant clonogenic cells against the in vitro cytotoxicity of bischloroethylnitrosourea (BCNU).
-
Cytoprotection of PEG-modified adult porcine pancreatic islets for improved xenotransplantation.
-
Cytosine methylation and suppression of O6-methylguanine-DNA methyltransferase expression in human rhabdomyosarcoma cell lines and xenografts.
-
Cytosolic TMEM88 promotes invasion and metastasis in lung cancer cells by binding DVLS.
-
Cytosolic branched chain aminotransferase (BCATc) mRNA is up-regulated in restricted brain areas of BDNF transgenic mice.
-
Cytosolic phospholipase A(2) activity associated with nuclei is not inhibited by arachidonyl trifluoromethyl ketone in macrophages stimulated with receptor-recognized forms of alpha(2)-macroglobulin.
-
Cytosolic phospholipase A2 alpha-deficient mice are resistant to experimental autoimmune encephalomyelitis.
-
Cytotoxic T lymphocyte antigen 4 (CTLA4) blockade accelerates the acute rejection of cardiac allografts in CD28-deficient mice: CTLA4 can function independently of CD28.
-
Cytotoxic effects of Mn(III) N-alkylpyridylporphyrins in the presence of cellular reductant, ascorbate.
-
Cytotoxic-T-lymphocyte-mediated elimination of target cells transduced with engineered adeno-associated virus type 2 vector in vivo.
-
Cytotoxicity of alpha-particle-emitting astatine-211-labelled antibody in tumour spheroids: no effect of hyperthermia.
-
D-Amino acid peptide residualizing agents bearing N-hydroxysuccinimido- and maleimido-functional groups and their application for trastuzumab radioiodination.
-
D6.1, a murine antimelanoma monoclonal antibody from congenitally athymic nude mice immunized with purified melanoma tumor-associated antigen.
-
DDR2 upregulation confers ferroptosis susceptibility of recurrent breast tumors through the Hippo pathway.
-
DEK is a poly(ADP-ribose) acceptor in apoptosis and mediates resistance to genotoxic stress.
-
DEK over-expression promotes mitotic defects and micronucleus formation.
-
DEK proto-oncogene expression interferes with the normal epithelial differentiation program.
-
DEK regulates hematopoietic stem engraftment and progenitor cell proliferation.
-
DGK α and ζ Activities Control TH1 and TH17 Cell Differentiation.
-
DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration.
-
DMT1 expression is increased in the lungs of hypotransferrinemic mice.
-
DNA Methylation Indicates Susceptibility to Isoproterenol-Induced Cardiac Pathology and Is Associated With Chromatin States.
-
DNA Sequence Constraints Define Functionally Active Steroid Nuclear Receptor Binding Sites in Chromatin.
-
DNA delivery from hyaluronic acid-collagen hydrogels via a substrate-mediated approach
-
DNA delivery from matrix metalloproteinase degradable poly (ethylene glycol) hydrogels to mouse cloned mesenchymal stem cells
-
DNA fragments from F9 PyEC mutants increase expression of heterologous genes in transfected F9 cells.
-
DNA methylation atlas of the mouse brain at single-cell resolution.
-
DNA mismatch repair is required for the host innate response and controls cellular fate after influenza virus infection.
-
DNA regulatory sequences of the rat tyrosine hydroxylase gene direct correct catecholaminergic cell-type specificity of a human growth hormone reporter in the CNS of transgenic mice causing a dwarf phenotype.
-
DNA repair protein O6-alkylguanine-DNA alkyltransferase is phosphorylated by two distinct and novel protein kinases in human brain tumour cells.
-
DNA transfection of macaque and murine respiratory tissue is greatly enhanced by use of a nuclease inhibitor.
-
DNA vaccination by intradermal electroporation induces long-lasting immune responses in rhesus macaques.
-
DNA vaccine molecular adjuvants SP-D-BAFF and SP-D-APRIL enhance anti-gp120 immune response and increase HIV-1 neutralizing antibody titers.
-
DNA-PK facilitates piggyBac transposition by promoting paired-end complex formation.
-
DNA-remethylation around a STAT5-binding enhancer in the alphaS1-casein promoter is associated with abrupt shutdown of alphaS1-casein synthesis during acute mastitis.
-
DOK2 inhibits EGFR-mutated lung adenocarcinoma.
-
DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties.
-
DREADDing proglucagon neurons: a fresh look at metabolic regulation by the brain.
-
DVT: a new era in anticoagulant therapy.
-
DYT-TOR1A subcellular proteomics reveals selective vulnerability of the nuclear proteome to cell stress.
-
Dabigatran abrogates brain endothelial cell permeability in response to thrombin.
-
Daily oral consumption of hydrolyzed type 1 collagen is chondroprotective and anti-inflammatory in murine posttraumatic osteoarthritis.
-
Damage- and pathogen-associated molecular patterns play differential roles in late mortality after critical illness.
-
Dancing with different partners: protein kinase a phosphorylation of seven membrane-spanning receptors regulates their G protein-coupling specificity.
-
Data analysis: evaluation of nanoscale contrast agent enhanced CT scan to differentiate between benign and malignant lung cancer in mouse model.
-
Data and animal management software for large-scale phenotype screening.
-
Dax1 regulates testis cord organization during gonadal differentiation.
-
Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice.
-
De novo TRIM8 variants impair its protein localization to nuclear bodies and cause developmental delay, epilepsy, and focal segmental glomerulosclerosis.
-
De novo adipocyte differentiation from Pdgfrβ+ preadipocytes protects against pathologic visceral adipose expansion in obesity.
-
Deciphering the mechanisms of tumorigenesis in human pancreatic ductal epithelial cells.
-
Deciphering the tête-à-tête between the microbiota and the immune system.
-
Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging.
-
Decoding the olfactory map through targeted transcriptomics links murine olfactory receptors to glomeruli.
-
Deconstructing B cell tolerance to basement membranes.
-
Deconstructing behavioral neuropharmacology with cellular specificity.
-
Deconstructing the genesis of animal form.
-
Decreased PPAR gamma expression compromises perigonadal-specific fat deposition and insulin sensitivity.
-
Decreased S -Nitrosylation of Tissue Transglutaminase Contributes to Age-Related Increases in Vascular Stiffness
-
Decreased Th17 and antigen-specific humoral responses in CX₃ CR1-deficient mice in the collagen-induced arthritis model.
-
Decreased aquaporin expression leads to increased resistance to apoptosis in hepatocellular carcinoma.
-
Decreased autophagy and fuel switching occur in a senescent hepatic cell model system.
-
Decreased beta-adrenergic responsiveness following hypertrophy occurs only in cardiomyocytes that also re-express beta-myosin heavy chain.
-
Decreased cochlear DNA receptor staining in MRL.MpJ-Fas(lpr) autoimmune mice with hearing loss.
-
Decreased expression levels of CD22 and L-selectin on peripheral blood B lymphocytes from patients with bullous pemphigoid.
-
Decreased fibronectin expression in Met/HGF-mediated tumorigenesis.
-
Decreased outflow facility and Schlemm's canal defects in a mouse model of glaucoma.
-
Decreased physical function and increased pain sensitivity in mice deficient for type IX collagen.
-
Decreased platelet aggregation, increased bleeding time and resistance to thromboembolism in P2Y1-deficient mice.
-
Decreased tumorigenesis in mice with a Kras point mutation at C118.
-
Dectin-1 and IL-17A suppress murine asthma induced by Aspergillus versicolor but not Cladosporium cladosporioides due to differences in β-glucan surface exposure.
-
Deep-tissue SWIR imaging using rationally designed small red-shifted near-infrared fluorescent protein.
-
Deep-tissue anatomical imaging of mice using carbon nanotube fluorophores in the second near-infrared window.
-
Deep-tissue photoacoustic tomography of a genetically encoded near-infrared fluorescent probe.
-
Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency.
-
Defective PTH regulation of sodium-dependent phosphate transport in NHERF-1-/- renal proximal tubule cells and wild-type cells adapted to low-phosphate media.
-
Defective T cell development and function in the absence of Abelson kinases.
-
Defective antitumor responses in CX3CR1-deficient mice.
-
Defective beta-adrenergic receptor signaling precedes the development of dilated cardiomyopathy in transgenic mice with calsequestrin overexpression.
-
Defective coupling of apical PTH receptors to phospholipase C prevents internalization of the Na+-phosphate cotransporter NaPi-IIa in Nherf1-deficient mice.
-
Defective glucose-stimulated insulin release from perifused islets of C57BL/6J mice.
-
Defective glycolysis and calcium signaling underlie impaired insulin secretion in a transgenic mouse.
-
Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice.
-
Defective mesonephric cell migration is associated with abnormal testis cord development in C57BL/6J XY(Mus domesticus) mice.
-
Defective parathyroid hormone regulation of NHE3 activity and phosphate adaptation in cultured NHERF-1-/- renal proximal tubule cells.
-
Defective prolactin signaling impairs pancreatic β-cell development during the perinatal period.
-
Defective signaling in a subpopulation of CD4(+) T cells in the absence of Ca(2+)/calmodulin-dependent protein kinase IV.
-
Defective survival and activation of thymocytes in transgenic mice expressing a catalytically inactive form of Ca2+/calmodulin-dependent protein kinase IV.
-
Defects in intracellular trafficking of fungal cell wall synthases lead to aberrant host immune recognition.
-
Defects in mononuclear phagocytic system (MPS) function in autoimmune MRL-lpr/lpr mice.
-
Defects of prostate development and reproductive system in the estrogen receptor-alpha null male mice.
-
Defects of the heart, eye, and megakaryocytes in peroxisome proliferator activator receptor-binding protein (PBP) null embryos implicate GATA family of transcription factors.
-
Deferoxamine regulates neuroinflammation and iron homeostasis in a mouse model of postoperative cognitive dysfunction.
-
Deficiencies in pro-thyrotropin-releasing hormone processing and abnormalities in thermoregulation in Cpefat/fat mice.
-
Deficiencies in the Fanconi anemia DNA damage response pathway increase sensitivity to HPV-associated head and neck cancer.
-
Deficiency in Bak and Bax perturbs thymic selection and lymphoid homeostasis.
-
Deficiency of 5-lipoxygenase abolishes sex-related survival differences in MRL-lpr/lpr mice.
-
Deficiency of 5-lipoxygenase accelerates renal allograft rejection in mice.
-
Deficiency of COX-1 causes natriuresis and enhanced sensitivity to ACE inhibition.
-
Deficiency of Mucosal-Associated Invariant T Cells in TCRJα18 Germline Knockout Mice.
-
Deficiency of Shank2 causes mania-like behavior that responds to mood stabilizers.
-
Deficiency of activation-induced cytidine deaminase in a murine model of ulcerative colitis.
-
Deficiency of asparagine synthetase causes congenital microcephaly and a progressive form of encephalopathy.
-
Deficiency of double-strand DNA break repair does not impair Mycobacterium tuberculosis virulence in multiple animal models of infection.
-
Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis.
-
Deficiency of heme-regulated eIF2alpha kinase decreases hepcidin expression and splenic iron in HFE-/- mice.
-
Deficiency of optineurin enhances osteoclast differentiation by attenuating the NRF2-mediated antioxidant response.
-
Deficiency of the lipid synthesis enzyme, DGAT1, extends longevity in mice.
-
Deficiency of the placenta- and yolk sac-specific tristetraprolin family member ZFP36L3 identifies likely mRNA targets and an unexpected link to placental iron metabolism.
-
Deficiency of α-actinin-3 is associated with increased susceptibility to contraction-induced damage and skeletal muscle remodeling.
-
Deficits in passive avoidance and fear behavior following bilateral and unilateral amygdala lesions in mice.
-
Deficits in reproduction and pro-gonadotropin-releasing hormone processing in male Cpefat mice.
-
Defined conditions for long-term expansion of murine and human alveolar epithelial stem cells in three-dimensional cultures.
-
Defining Potential Vaccine Targets of Haemophilus ducreyi Trimeric Autotransporter Adhesin DsrA.
-
Defining Transcription Regulatory Elements in the Human Frataxin Gene: Implications for Gene Therapy.
-
Defining a link with autosomal-dominant polycystic kidney disease in mice with congenitally low expression of Pkd1.
-
Defining a second epitope for heparin-induced thrombocytopenia/thrombosis antibodies using KKO, a murine HIT-like monoclonal antibody.
-
Defining fibronectin's cell adhesion synergy site by site-directed mutagenesis.
-
Defining the cooperative genetic changes that temporally drive alveolar rhabdomyosarcoma.
-
Definition of a novel cellular constituent of the bone marrow that regulates the response of immature B cells to B cell antigen receptor engagement.
-
Degenerative joint changes following intra-articular fracture are more severe in mice with T cell deficiency.
-
Deglutarylation of glutaryl-CoA dehydrogenase by deacylating enzyme SIRT5 promotes lysine oxidation in mice.
-
Delayed fracture healing and increased callus adiposity in a C57BL/6J murine model of obesity-associated type 2 diabetes mellitus.
-
Delayed wound healing in the absence of intercellular adhesion molecule-1 or L-selectin expression.
-
Deletion and site-directed mutagenesis of the ATP-binding motif (P-loop) in the bifunctional murine ATP-sulfurylase/adenosine 5'-phosphosulfate kinase enzyme.
-
Deletion of Atm in Tumor but not Endothelial Cells Improves Radiation Response in a Primary Mouse Model of Lung Adenocarcinoma.
-
Deletion of CD4 and CD8 coreceptors permits generation of alphabetaT cells that recognize antigens independently of the MHC.
-
Deletion of CaMKK2 from the liver lowers blood glucose and improves whole-body glucose tolerance in the mouse.
-
Deletion of GαZ protein protects against diet-induced glucose intolerance via expansion of β-cell mass.
-
Deletion of MLIP (muscle-enriched A-type lamin-interacting protein) leads to cardiac hyperactivation of Akt/mammalian target of rapamycin (mTOR) and impaired cardiac adaptation.
-
Deletion of Nrf2 enhances susceptibility to eosinophilic sinonasal inflammation in a murine model of rhinosinusitis.
-
Deletion of PIK3C3/Vps34 in sensory neurons causes rapid neurodegeneration by disrupting the endosomal but not the autophagic pathway.
-
Deletion of Trpm7 disrupts embryonic development and thymopoiesis without altering Mg2+ homeostasis.
-
Deletion of Y chromosome sequences located outside the testis determining region can cause XY female sex reversal.
-
Deletion of a conserved cis-element in the Ifng locus highlights the role of acute histone acetylation in modulating inducible gene transcription.
-
Deletion of a splicing enhancer disrupts PLP1/DM20 ratio and myelin stability.
-
Deletion of angiotensin II type 2 receptor accelerates adipogenesis in murine mesenchymal stem cells via Wnt10b/beta-catenin signaling.
-
Deletion of p16 and p15 genes in brain tumors.
-
Deletion of p47phox attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice.
-
Deletion of presenilin 1 hydrophilic loop sequence leads to impaired gamma-secretase activity and exacerbated amyloid pathology.
-
Deletion of the carboxyl terminus of Tie2 enhances kinase activity, signaling, and function. Evidence for an autoinhibitory mechanism.
-
Deletion of the glucagon receptor gene before and after experimental diabetes reveals differential protection from hyperglycemia.
-
Deletion of the glutamate carboxypeptidase II gene in mice reveals a second enzyme activity that hydrolyzes N-acetylaspartylglutamate.
-
Deletion of the p16INK4a tumor suppressor and expression of the androgen receptor induce sarcomatoid carcinomas with signet ring cells in the mouse prostate.
-
Deletion of the phosphatase INPP5E in the murine retina impairs photoreceptor axoneme formation and prevents disc morphogenesis.
-
Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle.
-
Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding.
-
Delineation of a FOXA1/ERα/AGR2 regulatory loop that is dysregulated in endocrine therapy-resistant breast cancer.
-
Delivery of chemo-sensitizing siRNAs to HER2+-breast cancer cells using RNA aptamers.
-
Delivery of small molecule mast cell activators for West Nile Virus vaccination using acetalated dextran microparticles.
-
Delivery of viral vectors to tumor cells: extracellular transport, systemic distribution, and strategies for improvement.
-
Delivery rate affects uptake of a fluorescent glucose analog in murine metastatic breast cancer.
-
Delivery-corrected imaging of fluorescently-labeled glucose reveals distinct metabolic phenotypes in murine breast cancer.
-
Delta-like 1-Lysine613 regulates notch signaling.
-
DeltaFosB in brain reward circuits mediates resilience to stress and antidepressant responses.
-
Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch1.
-
Demineralized Murine Skeletal Histology.
-
Demineralized murine skeletal histology.
-
Demonstration that mutation of the type II transforming growth factor beta receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells.
-
Dendritic Cells Interpret Haptotactic Chemokine Gradients in a Manner Governed by Signal-to-Noise Ratio and Dependent on GRK6.
-
Dendritic cell responses to early murine cytomegalovirus infection: subset functional specialization and differential regulation by interferon alpha/beta.
-
Dendritic cell transmigration through brain microvessel endothelium is regulated by MIP-1alpha chemokine and matrix metalloproteinases.
-
Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice.
-
Dendritic cell/macrophage precursors capture exogenous antigen for MHC class I presentation by dendritic cells.
-
Dendritic cells engineered to secrete anti-GITR antibodies are effective adjuvants to dendritic cell-based immunotherapy.
-
Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo.
-
Dendritic cells pulsed with a tumor-specific peptide induce long-lasting immunity and are effective against murine intracerebral melanoma.
-
Dendritic cells with TGF-beta1 differentiate naive CD4+CD25- T cells into islet-protective Foxp3+ regulatory T cells.
-
Dendritic epidermal T cells regulate skin antimicrobial barrier function.
-
Dendritic-NK cell interactions in P. gingivalis-specific responses.
-
Dengue virus-elicited tryptase induces endothelial permeability and shock.
-
Dependence of corneal stem/progenitor cells on ocular surface innervation.
-
Dependence of germinal center B cells on expression of CD21/CD35 for survival.
-
Depleting regulatory T cells with arginine-rich, cell-penetrating, peptide-conjugated morpholino oligomer targeting FOXP3 inhibits regulatory T-cell function.
-
Depletion of casein kinase II by antisense oligonucleotide prevents neuritogenesis in neuroblastoma cells.
-
Depletion of catalytic and regulatory subunits of protein kinase CK2 by antisense oligonucleotide treatment of neuroblastoma cells.
-
Depletion of dendritic cells delays ovarian cancer progression by boosting antitumor immunity.
-
Depletion of passenger leukocytes from corneal grafts: an effective means of promoting transplant survival?
-
Depletion of polymorphonuclear leukocytes has no effect on preterm delivery in a mouse model of Escherichia coli-induced labor.
-
Depletion-Resistant CD4 T Cells Enhance Thymopoiesis During Lymphopenia.
-
Depolarization-stimulated cholecystokinin secretion is mediated by L-type calcium channels in STC-1 cells.
-
Depressed expression of adipocyte beta-adrenergic receptors is a common feature of congenital and diet-induced obesity in rodents.
-
Depression of macrophage function by a factor produced by neoplasms: a merchanism for abrogation of immune surveillance.
-
Depression of murine macrophage accumulation by low-molecular-weight derived from spontaneous mammary carcinomas.
-
Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2.
-
Derivation of a biologically contained replication system for human immunodeficiency virus type 1.
-
Derivation of chondrogenically-committed cells from human embryonic cells for cartilage tissue regeneration.
-
Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture.
-
Derivation of therapeutic lung spheroid cells from minimally invasive transbronchial pulmonary biopsies.
-
Dermal adipose tissue has high plasticity and undergoes reversible dedifferentiation in mice.
-
Description of monoclonal antibody defining an HLA allotypic determinant that includes specificities within the B5 cross-reacting group.
-
Desensitization of angiotensin receptor function.
-
Desensitization of the mouse thromboxane A2 receptor (TP) by G protein-coupled receptor kinases (Grks).
-
Desert Hedgehog/Patched 1 signaling specifies fetal Leydig cell fate in testis organogenesis.
-
Design and Analysis of Large-Scale Biological Rhythm Studies: A Comparison of Algorithms for Detecting Periodic Signals in Biological Data
-
Design and characterization of a peptide mimotope of the HIV-1 gp120 bridging sheet.
-
Design and characterization of microporous hyaluronic acid hydrogels for in vitro gene transfer to mMSCs
-
Design and validation of a dynamic cell-culture system for bone biology research and exogenous tissue-engineering applications.
-
Design of a novel small peptide targeted against a tumor-specific receptor.
-
Design of a superconducting volume coil for magnetic resonance microscopy of the mouse brain.
-
Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Aromatic Aldehydes as Drug Candidates for the Treatment of Sickle Cell Disease.
-
Design, Synthesis, and Mechanism Study of Benzenesulfonamide-Containing Phenylalanine Derivatives as Novel HIV-1 Capsid Inhibitors with Improved Antiviral Activities.
-
Designer monotransregulators provide a basis for a transcriptional therapy for de novo endocrine-resistant breast cancer.
-
Desmin interacts with STIM1 and coordinates Ca2+ signaling in skeletal muscle.
-
Desmoplakin controls microvilli length but not cell adhesion or keratin organization in the intestinal epithelium.
-
Desmoplakin: an unexpected regulator of microtubule organization in the epidermis.
-
Destruction of Myc by ubiquitin-mediated proteolysis: cancer-associated and transforming mutations stabilize Myc.
-
Detailed analysis of gene expression during development of T cell lineages in the thymus.
-
Detecting and characterizing circular RNAs.
-
Detection of Ebola virus envelope using monoclonal and polyclonal antibodies in ELISA, surface plasmon resonance and a quartz crystal microbalance immunosensor.
-
Detection of Escherichia coli enterotoxins in stools.
-
Detection of Lung Nodules in Micro-CT Imaging Using Deep Learning.
-
Detection of a transformation-specific glycopeptide in SSV-infected cells.
-
Detection of acrolein-derived cyclic DNA adducts in human cells by monoclonal antibodies.
-
Detection of cytosolic bacteria by inflammatory caspases.
-
Detection of early changes in renal function using 99mTc-MAG3 imaging in a murine model of ischemia-reperfusion injury.
-
Detection of iron-labeled single cells by MR imaging based on intermolecular double quantum coherences at 14 T.
-
Detection of metastatic tumors in nude mice: brief communication.
-
Detection of mouse cytomegalovirus nucleic acid in latently infected mice by in vitro enzymatic amplification.
-
Detection of murine cytomegalovirus immediate early 1 transcripts in the spleens of latently infected mice.
-
Detection of near-atmospheric concentrations of CO2 by an olfactory subsystem in the mouse.
-
Detection of oncornavirus antigenic activity in human urothelial tissues.
-
Detection of pathogen-specific antibodies by loop-mediated isothermal amplification.
-
Detection of the major glycoproteins of Friend leukemia virus (gp71) and the murine mammary tumor virus (gp52) on the surface of mouse cells.
-
Determinants of PF4/heparin immunogenicity.
-
Determinants of the source of cytomegalovirus in murine renal allograft recipients.
-
Determination of an angiotensin II-regulated proteome in primary human kidney cells by stable isotope labeling of amino acids in cell culture (SILAC).
-
Determination of electric parameters of cell membranes by a dielectrophoresis method.
-
Determination of estrogen receptor messenger ribonucleic acid (mRNA) and cytochrome P450 aromatase mRNA levels in adipocytes and adipose stromal cells by competitive polymerase chain reaction amplification.
-
Determination of the functional status of alloreactive T cells by interferon-gamma kinetics.
-
Determining γδ versus αß T cell development.
-
Developing an HIV vaccine.
-
Developing nodes of Ranvier are defined by ankyrin-G clustering and are independent of paranodal axoglial adhesion.
-
Development and Efficacy of an Orally Bioavailable Selective TAK1 Inhibitor for the Treatment of Inflammatory Arthritis.
-
Development and Evaluation of a Novel Mouse Model of Asphyxial Cardiac Arrest Revealed Severely Impaired Lymphopoiesis After Resuscitation.
-
Development and Preliminary Evaluation of a Murine Model of Chronic Radiation-Induced Proctitis.
-
Development and application of basic research techniques in bladder cancer research.
-
Development and biological evaluation of ⁹⁹mTc-sulfonamide derivatives for in vivo visualization of CA IX as surrogate tumor hypoxia markers.
-
Development and characterization of a fusion protein between thermally responsive elastin-like polypeptide and interleukin-1 receptor antagonist: sustained release of a local antiinflammatory therapeutic.
-
Development and characterization of a monoclonal antibody to human embryonal carcinoma.
-
Development and distribution of a human B cell subpopulation identified by the HB-4 monoclonal antibody.
-
Development and preclinical evaluation of an alphavirus replicon particle vaccine for cytomegalovirus.
-
Development and preclinical evaluation of an alphavirus replicon vaccine for influenza.
-
Development and use of SIV-based Integrase defective lentiviral vector for immunization.
-
Development and validation of a cell-based fluorescent method for measuring antibody affinity.
-
Development and validation of a method for using breast core needle biopsies for gene expression microarray analyses.
-
Development of Aggressive Pancreatic Ductal Adenocarcinomas Depends on Granulocyte Colony Stimulating Factor Secretion in Carcinoma Cells.
-
Development of DNA Vaccine Targeting E6 and E7 Proteins of Human Papillomavirus 16 (HPV16) and HPV18 for Immunotherapy in Combination with Recombinant Vaccinia Boost and PD-1 Antibody.
-
Development of DX-9065a, a novel direct factor Xa antagonist, in cardiovascular disease.
-
Development of Novel 18
F-PET Agents for Tumor Hypoxia Imaging.
-
Development of Patient-specific AAV Vectors After Neutralizing Antibody Selection for Enhanced Muscle Gene Transfer.
-
Development of Saccharomyces cerevisiae as a model pathogen. A system for the genetic identification of gene products required for survival in the mammalian host environment.
-
Development of a 4-D digital mouse phantom for molecular imaging research.
-
Development of a broadly active influenza intranasal vaccine adjuvanted with self-assembled particles composed of mastoparan-7 and CpG.
-
Development of a colon cancer GEMM-derived orthotopic transplant model for drug discovery and validation.
-
Development of a fluorescence detection system using optical parametric oscillator (OPO) laser excitation for in vivo diagnosis.
-
Development of a high-efficiency method for gene marking of Dunning prostate cancer cell lines with the enzyme beta-galactosidase.
-
Development of a membrane-anchored chemerin receptor agonist as a novel modulator of allergic airway inflammation and neuropathic pain.
-
Development of a model of melphalan-induced gastrointestinal toxicity in mice.
-
Development of a monoclonal antibody specific for serotype 3 rotavirus strains.
-
Development of a novel adjuvanted nasal vaccine: C48/80 associated with chitosan nanoparticles as a path to enhance mucosal immunity.
-
Development of a precision medicine pipeline to identify personalized treatments for colorectal cancer.
-
Development of a recombinant yellow fever vector expressing a HIV clade C founder envelope gp120.
-
Development of a simplified spinal cord ischemia model in mice.
-
Development of an ER action indicator mouse for the study of estrogens, selective ER modulators (SERMs), and Xenobiotics.
-
Development of an advanced hyperspectral imaging (HSI) system with applications for cancer detection.
-
Development of an aerosol model of Cryptococcus reveals humidity as an important factor affecting the viability of Cryptococcus during aerosolization.
-
Development of bioactive photocrosslinkable fibrous hydrogels.
-
Development of germ cells in the mouse.
-
Development of glomerular pattern visualized in the olfactory bulbs of living mice.
-
Development of iron-containing multiwalled carbon nanotubes for MR-guided laser-induced thermotherapy.
-
Development of mammary hyperplasia and neoplasia in MMTV-TGF alpha transgenic mice.
-
Development of pemphigus vulgaris-like lesions in severe combined immunodeficiency disease mice reconstituted with lymphocytes from patients.
-
Development, validation and characterization of a novel mouse model of Adynamic Bone Disease (ABD).
-
Development-dependent disappearance of caspase-3 in skeletal muscle is post-transcriptionally regulated.
-
Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity.
-
Developmental activation of the TCR alpha enhancer requires functional collaboration among proteins bound inside and outside the core enhancer.
-
Developmental and spatial patterns of expression of the mouse homeobox gene, Hox 2.1.
-
Developmental and transformation-sensitive expression of the Sparc gene on mouse chromosome 11.
-
Developmental biology. Another hit for gene targeting.
-
Developmental biology. Branching takes nerve.
-
Developmental biology. The making of the ear.
-
Developmental biology: decisions, decisions!
-
Developmental defects in mouse embryos lacking N-cadherin.
-
Developmental exposure to noninherited maternal antigens induces CD4+ T regulatory cells: relevance to mechanism of heart allograft tolerance.
-
Developmental expression of 2ar (osteopontin) and SPARC (osteonectin) RNA as revealed by in situ hybridization.
-
Developmental expression of glycogenolytic enzymes in rabbit tissues: possible relationship to fetal lung maturation.
-
Developmental expression of renal angiotensin II receptor genes in the mouse.
-
Developmental expression of tissue inhibitor of metalloproteinase (TIMP) RNA.
-
Developmental onset of enduring long-term potentiation in mouse hippocampus.
-
Developmental regulation of VDJ recombination by the core fragment of the T cell receptor alpha enhancer.
-
Developmental regulation of alpha beta T cell antigen receptor expression results from differential stability of nascent TCR alpha proteins within the endoplasmic reticulum of immature and mature T cells.
-
Developmental regulation of apical endocytosis controls epithelial patterning in vertebrate tubular organs.
-
Developmental regulation of cytochrome oxidase subunit VIa isoforms in cardiac and skeletal muscle.
-
Developmental regulation of lymphocyte-specific protein 1 (LSP1) expression in thymus during human T-cell maturation.
-
Developmental regulation of mouse SPARC (osteonectin) gene expression.
-
Developmental renin expression in mice with a defective renin-angiotensin system.
-
Developmental roles of pufferfish Hox clusters and genome evolution in ray-fin fish.
-
Developmental stage-dependent effects of cardiac fibroblasts on function of stem cell-derived engineered cardiac tissues.
-
Developmental stratification of the mammary epithelium occurs through symmetry-breaking vertical divisions of apically positioned luminal cells.
-
Developmentally regulated changes in femoral nerve regeneration in the mouse and rat.
-
Dexamethasone potentiates in vitro blood-brain barrier recovery after primary blast injury by glucocorticoid receptor-mediated upregulation of ZO-1 tight junction protein.
-
Dexamethasone-induced immunosuppression: mechanisms and implications for immunotherapy.
-
Dexmedetomidine provides renoprotection against ischemia-reperfusion injury in mice.
-
Diabetes causes NLRP3-dependent barrier dysfunction in mice with detrusor overactivity but not underactivity.
-
Diabetes insipidus in uricase-deficient mice: a model for evaluating therapy with poly(ethylene glycol)-modified uricase.
-
Diabetic bladder dysfunction progresses from an overactive to an underactive phenotype in a type-1 diabetic mouse model (Akita female mouse) and is dependent on NLRP3.
-
Diabetic kidney disease in FVB/NJ Akita mice: temporal pattern of kidney injury and urinary nephrin excretion.
-
Diabetic liver injury from streptozotocin is regulated through the caspase-8 homolog cFLIP involving activation of JNK2 and intrahepatic immunocompetent cells.
-
Diabetic nephropathy: of mice and men.
-
Diacylglycerol acyltranferase 1 anti-sense oligonucleotides reduce hepatic fibrosis in mice with nonalcoholic steatohepatitis.
-
Diacylglycerol kinase zeta positively controls the development of iNKT-17 cells.
-
Diacylglycerol kinase zeta regulates actin cytoskeleton reorganization through dissociation of Rac1 from RhoGDI.
-
Diacylglycerol kinase zeta regulates microbial recognition and host resistance to Toxoplasma gondii.
-
Diacylglycerol kinase ζ deficiency in a non-CD4(+) T-cell compartment leads to increased peanut hypersensitivity.
-
Diacylglycerol kinase ζ limits B cell antigen receptor-dependent activation of ERK signaling to inhibit early antibody responses.
-
Diagnosis of partial body radiation exposure in mice using peripheral blood gene expression profiles.
-
Diagnostic assay to assist clinical decisions for unclassified severe combined immune deficiency.
-
Diarrhoea associated with heat-stable enterotoxin-producing strains of Escherichia coli.
-
Diarylureas are small-molecule inhibitors of insulin-like growth factor I receptor signaling and breast cancer cell growth.
-
Diazoxide restores beta3-adrenergic receptor function in diet-induced obesity and diabetes.
-
Dicistronic polioviruses as expression vectors for foreign genes.
-
Dickkopf-1 promotes hematopoietic regeneration via direct and niche-mediated mechanisms.
-
Dielectrophoresis and electrorotation of neurospora slime and murine myeloma cells.
-
Diet Alters Entero-Mammary Signaling to Regulate the Breast Microbiome and Tumorigenesis.
-
Diet and sex modify exercise and cardiac adaptation in the mouse.
-
Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment.
-
Diet-induced changes in uncoupling proteins in obesity-prone and obesity-resistant strains of mice.
-
Diet-induced obese mice retain endogenous leptin action.
-
Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice.
-
Diet-induced obesity significantly increases the severity of posttraumatic arthritis in mice.
-
Diet-induced type II diabetes in C57BL/6J mice.
-
Dietary Restriction and AMPK Increase Lifespan via Mitochondrial Network and Peroxisome Remodeling.
-
Dietary Salt Exacerbates Experimental Colitis.
-
Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins.
-
Dietary factors alter hepatic innate immune system in mice with nonalcoholic fatty liver disease.
-
Dietary fatty acid content regulates wound repair and the pathogenesis of osteoarthritis following joint injury.
-
Dietary flavonoid naringenin induces regulatory T cells via an aryl hydrocarbon receptor mediated pathway.
-
Dietary isothiocyanate-induced apoptosis via thiol modification of DNA topoisomerase IIα.
-
Dietary manipulation of serotonergic and dopaminergic function in C57BL/6J mice with amino acid depletion mixtures.
-
Dietary methionine influences therapy in mouse cancer models and alters human metabolism.
-
Dietary nitrate attenuates renal ischemia-reperfusion injuries by modulation of immune responses and reduction of oxidative stress.
-
Dietary supplementation with fresh pineapple juice decreases inflammation and colonic neoplasia in IL-10-deficient mice with colitis.
-
Dietary ω-3 polyunsaturated fatty acids decrease retinal neovascularization by adipose-endoplasmic reticulum stress reduction to increase adiponectin.
-
Differences in V kappa gene utilization and VH CDR3 sequence among anti-DNA from C3H-lpr mice and lupus mice with nephritis.
-
Differences in intraepithelial lymphocyte T cell subsets isolated from murine small versus large intestine.
-
Differences in the Antinociceptive Effects and Binding Properties of Propranolol and Bupranolol Enantiomers.
-
Differences in the absorption, metabolism and biliary excretion of a diastereomeric pair of alphavbeta3-antagonists in rat: limited role of P-glycoprotein.
-
Differences in the central anorectic effects of glucagon-like peptide-1 and exendin-4 in rats.
-
Different effects of glucose starvation on expression and stability of VEGF mRNA isoforms in murine ovarian cancer cells.
-
Different immune cells mediate mechanical pain hypersensitivity in male and female mice.
-
Different mechanisms preclude mutant CLDN14 proteins from forming tight junctions in vitro.
-
Different presynaptic roles of synapsins at excitatory and inhibitory synapses.
-
Different roles for matrix metalloproteinase-2 and matrix metalloproteinase-9 in the pathogenesis of cardiac allograft rejection.
-
Different secretory pathways of renin from mouse cells transfected with the human renin gene.
-
Differential Cell Susceptibilities to KrasG12D in the Setting of Obstructive Chronic Pancreatitis.
-
Differential Control of iNKT Cell Effector Lineage Differentiation by the Forkhead Box Protein O1 (Foxo1) Transcription Factor.
-
Differential Health Effects of Constant versus Intermittent Exposure to Formaldehyde in Mice: Implications for Building Ventilation Strategies.
-
Differential Immune Microenvironments and Response to Immune Checkpoint Blockade among Molecular Subtypes of Murine Medulloblastoma.
-
Differential Induction of Immunogenic Cell Death and Interferon Expression in Cancer Cells by Structured ssRNAs.
-
Differential Inhibition of Nav1.7 and Neuropathic Pain by Hybridoma-Produced and Recombinant Monoclonal Antibodies that Target Nav1.7 : Differential activities of Nav1.7-targeting monoclonal antibodies.
-
Differential Requirement for IRGM Proteins during Tuberculosis Infection in Mice.
-
Differential Role of B Cells and IL-17 Versus IFN-γ During Early and Late Rejection of Pig Islet Xenografts in Mice.
-
Differential Sensitivity to Ethanol-Induced Circadian Rhythm Disruption in Adolescent and Adult Mice.
-
Differential Sex Response to Aspirin in Decreasing Aneurysm Rupture in Humans and Mice.
-
Differential activity-dependent, homeostatic plasticity of two neocortical inhibitory circuits.
-
Differential anti-inflammatory effects of LPS in susceptible and resistant mouse strains.
-
Differential coordination demands in Fe versus Mn water-soluble cationic metalloporphyrins translate into remarkably different aqueous redox chemistry and biology.
-
Differential corticostriatal plasticity during fast and slow motor skill learning in mice.
-
Differential developmental toxicity of naphthoic acid isomers in medaka (Oryzias latipes) embryos.
-
Differential dynamics and activity-dependent regulation of alpha- and beta-neurexins at developing GABAergic synapses.
-
Differential effects of calorie restriction and rapamycin on age-related molecular and functional changes in skeletal muscle.
-
Differential effects of doxycycline, a broad-spectrum matrix metalloproteinase inhibitor, on angiotensin II-induced atherosclerosis and abdominal aortic aneurysms.
-
Differential effects of fat and sucrose on body composition in A/J and C57BL/6 mice.
-
Differential effects of fat and sucrose on the development of obesity and diabetes in C57BL/6J and A/J mice.
-
Differential effects of insulin-like growth factor (IGF)-binding protein-3 and its proteolytic fragments on ligand binding, cell surface association, and IGF-I receptor signaling.
-
Differential effects of toll-like receptor stimulation on mRNA-driven myogenic conversion of human and mouse fibroblasts.
-
Differential effects of vascular endothelial growth factor receptor-2 inhibitor ZD6474 on circulating endothelial progenitors and mature circulating endothelial cells: implications for use as a surrogate marker of antiangiogenic activity.
-
Differential expression of VEGF isoforms in mouse during development and in the adult.
-
Differential expression of a sialoglycoprotein with an approximate molecular weight of 900,000 on metastatic human colon carcinoma cells growing in culture and in tumor tissues.
-
Differential expression of genes encoding TGFs beta 1, beta 2, and beta 3 during murine palate formation.
-
Differential expression of intracellular and secreted osteopontin isoforms by murine macrophages in response to toll-like receptor agonists.
-
Differential expression of microRNAs among cell populations in the regenerating adult mouse olfactory epithelium.
-
Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo.
-
Differential expression of p63 isoforms in female reproductive organs.
-
Differential expression of procollagen genes between mid- and late-gestational fetal fibroblasts.
-
Differential functions for the transcription factor E2A in positive and negative gene regulation in pre-B lymphocytes.
-
Differential gene expression in mouse sclera during ocular development.
-
Differential gene expression in the distal tip endoderm of the embryonic mouse lung.
-
Differential glycemic effects of morphine in diabetic and normal mice.
-
Differential inflammatory responses of the native left and right ventricle associated with donor heart preservation.
-
Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.
-
Differential mechanisms of morphine antinociceptive tolerance revealed in (beta)arrestin-2 knock-out mice.
-
Differential molecular mechanism of the estrogen action that regulates lactoferrin gene in human and mouse.
-
Differential myocardial gene expression in the development and rescue of murine heart failure.
-
Differential osteopontin expression in phenotypically distinct subclones of murine breast cancer cells mediates metastatic behavior.
-
Differential phosphorylation of functional tyrosines in CD19 modulates B-lymphocyte activation.
-
Differential psychostimulant-induced activation of neural circuits in dopamine transporter knockout and wild type mice.
-
Differential pulmonary transcriptomic profiles in murine lungs infected with low and highly virulent influenza H3N2 viruses reveal dysregulation of TREM1 signaling, cytokines, and chemokines.
-
Differential regulation of MeCP2 phosphorylation in the CNS by dopamine and serotonin.
-
Differential regulation of calcineurin isoforms in transplant patients: a new look at an old problem.
-
Differential regulation of primary and memory CD8 T cell immune responses by diacylglycerol kinases.
-
Differential regulation of proteasome function in isoproterenol-induced cardiac hypertrophy.
-
Differential regulation of renin and Cox-2 expression in the renal cortex of C57Bl/6 mice.
-
Differential regulation of the PGC family of genes in a mouse model of Staphylococcus aureus sepsis.
-
Differential requirement for the SAP-Fyn interaction during NK T cell development and function.
-
Differential requirement of RasGRP1 for γδ T cell development and activation.
-
Differential requirements for NAIP5 in activation of the NLRC4 inflammasome.
-
Differential response of ventral midbrain and striatal progenitor cells to lesions of the nigrostriatal dopaminergic projection.
-
Differential screening of a subtracted cDNA library: a method to search for genes preferentially expressed in multiple tissues.
-
Differential seizure sensitivities to picrotoxinin in two inbred strains of mice (DBA/2J and BALB/c ByJ): parallel changes in GABA receptor-mediated chloride flux and receptor binding.
-
Differential susceptibility to acetaminophen-induced liver injury in sub-strains of C57BL/6 mice: 6N versus 6J.
-
Differential uptake of DNA–poly (ethylenimine) polyplexes in cells cultured on collagen and fibronectin surfaces
-
Differentiated Daughter Cells Regulate Stem Cell Proliferation and Fate through Intra-tissue Tension.
-
Differentiation of a catecholaminergic CNS cell line modifies tyrosine hydroxylase transcriptional regulation.
-
Differentiation of erythroleukemia cells in vitro: properties of chemical inducers.
-
Differentiation of fetal sertoli cells in the adult testis.
-
Differentiation of human T lymphocytes. I. Acquisition of a novel human cell surface protein (p80) during normal intrathymic T cell maturation.
-
Differentiation of mammalian skeletal muscle cells cultured on microcarrier beads in a rotating cell culture system.
-
Differentiation potential of individual olfactory c-Kit+ progenitors determined via multicolor lineage tracing.
-
Differentiation- and stress-dependent nuclear cytoplasmic redistribution of myopodin, a novel actin-bundling protein.
-
Diffusion tensor imaging analysis of the brain in the canine model of Krabbe disease.
-
Diffusion tensor imaging using multiple coils for mouse brain connectomics.
-
Difluoromethylornithine is a novel inhibitor of Helicobacter pylori growth, CagA translocation, and interleukin-8 induction.
-
Digital atlasing and standardization in the mouse brain.
-
Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity.
-
Dilated cardiomyopathy in transgenic mice expressing a mutant A subunit of protein phosphatase 2A.
-
Dimerization and ubiquitin mediated recruitment of A20, a complex deubiquitinating enzyme.
-
Dimerization of NF-KB2 with RelA(p65) regulates DNA binding, transcriptional activation, and inhibition by an I kappa B-alpha (MAD-3).
-
Dioxin induces transcription of fos and jun genes by Ah receptor-dependent and -independent pathways.
-
Diphenhydramine increases the therapeutic window for platinum drugs by simultaneously sensitizing tumor cells and protecting normal cells.
-
Diphtheria toxin-epidermal growth factor fusion protein DAB389EGF for the treatment of bladder cancer.
-
Dipyridamole-cisplatin potentiation: enhanced in vivo cytotoxicity in xenograft models of human testicular and bladder cancers.
-
Direct Actions of AT1 (Type 1 Angiotensin) Receptors in Cardiomyocytes Do Not Contribute to Cardiac Hypertrophy.
-
Direct Conversion of Human Pluripotent Stem Cells to Osteoblasts With a Small Molecule.
-
Direct binding of activated c-Src to the beta 3-adrenergic receptor is required for MAP kinase activation.
-
Direct correlation between DNA repair capacity and metastatic potential of K-1735 murine melanoma cells.
-
Direct demonstration of elevated aldehyde dehydrogenase in human hematopoietic progenitor cells.
-
Direct in vivo evidence for tumor propagation by glioblastoma cancer stem cells.
-
Direct in vivo measurement of targeted binding in a human tumor xenograft.
-
Direct interaction of Gas11 with microtubules: implications for the dynein regulatory complex.
-
Direct measurement of hypoxia in a xenograft multiple myeloma model by optical-resolution photoacoustic microscopy.
-
Direct reprogramming of cardiac fibroblasts to cardiomyocytes using microRNAs.
-
Direct sequencing of the activation peptide and the catalytic domain of the factor IX gene in six species.
-
Direct vaccination with tumor cells killed with ICP4-deficient HSVd120 elicits effective antitumor immunity.
-
Direct visualization of cardiac transcription factories reveals regulatory principles of nuclear architecture during pathological remodeling.
-
Direct-contact co-culture between smooth muscle and endothelial cells inhibits TNF-alpha-mediated endothelial cell activation.
-
Directed differentiation and neurite extension of mouse embryonic stem cell on aligned poly(lactide) nanofibers functionalized with YIGSR peptide.
-
Directed enzyme pro-drug gene therapy for pancreatic cancer in vivo.
-
Directed in vitro myogenesis of human embryonic stem cells and their in vivo engraftment.
-
Directed intermixing in multicomponent self-assembling biomaterials.
-
Directing and Potentiating Stem Cell-Mediated Angiogenesis and Tissue Repair by Cell Surface E-Selectin Coating.
-
Directionality of temperature activation in mouse TRPA1 ion channel can be inverted by single-point mutations in ankyrin repeat six.
-
Disc1 regulates granule cell migration in the developing hippocampus.
-
Discordance between GLP-1R gene and protein expression in mouse pancreatic islet cells.
-
Discordant complement systems as a factor in hyperacute xenograft rejection.
-
Discordant on/off switching of gene expression in myocytes during cardiac hypertrophy in vivo.
-
Discovery and characterization of small molecules that target the GTPase Ral.
-
Discovery and fine mapping of serum protein loci through transethnic meta-analysis.
-
Discovery and optimization of imidazo[1,2-a]pyridine inhibitors of insulin-like growth factor-1 receptor (IGF-1R).
-
Discovery of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a novel and potent vascular endothelial growth factor receptor inhibitor.
-
Discovery of 6-Fluoro-5-(R)-(3-(S)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)-2-methylphenyl)-2-(S)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1H-carbazole-8-carboxamide (BMS-986142): A Reversible Inhibitor of Bruton's Tyrosine Kinase (BTK) Conformationally Constrained by Two Locked Atropisomers.
-
Discovery of Age-Related Protein Folding Stability Differences in the Mouse Brain Proteome.
-
Discovery of Druggable Host Factors Critical to Plasmodium Liver-Stage Infection.
-
Discovery of LSZ102, a Potent, Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer.
-
Discovery of Selective Estrogen Receptor Covalent Antagonists for the Treatment of ERαWT and ERαMUT Breast Cancer.
-
Discovery of [(3-bromo-7-cyano-2-naphthyl)(difluoro)methyl]phosphonic acid, a potent and orally active small molecule PTP1B inhibitor.
-
Discovery of a functionally selective ghrelin receptor (GHSR1a) ligand for modulating brain dopamine.
-
Discovery of a novel Toxoplasma gondii conoid-associated protein important for parasite resistance to reactive nitrogen intermediates.
-
Discovery of a potent GIPR peptide antagonist that is effective in rodent and human systems.
-
Discovery of an inhibitor of insulin-like growth factor 1 receptor activation: implications for cellular potency and selectivity over insulin receptor.
-
Discovery of biomarker candidates for coronary artery disease from an APOE-knock out mouse model using iTRAQ-based multiplex quantitative proteomics.
-
Discovery of novel ligands for mouse olfactory receptor MOR42-3 using an in silico screening approach and in vitro validation.
-
Discovery of novel targets of quinoline drugs in the human purine binding proteome.
-
Discovery of protein- and DNA-imperceptible nanoparticle hard coating using gel-based reaction tuning.
-
Discovery of thiophene inhibitors of polo-like kinase.
-
Discovery of β-Arrestin Biased, Orally Bioavailable, and CNS Penetrant Neurotensin Receptor 1 (NTR1) Allosteric Modulators.
-
Discovery of β-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy.
-
Discrete amino acid sequences of the alpha 1-adrenergic receptor determine the selectivity of coupling to phosphatidylinositol hydrolysis.
-
Discs of mammalian rod photoreceptors form through the membrane evagination mechanism.
-
Disease progression in iridocorneal angle tissues of BMP2-induced ocular hypertensive mice with optical coherence tomography.
-
Disease-Specific Expression of Conjunctiva Associated Lymphoid Tissue (CALT) in Mouse Models of Dry Eye Disease and Ocular Allergy.
-
Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy.
-
Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4.
-
Disialoganglioside GD2 in human neuroectodermal tumor cell lines and gliomas.
-
Disparate adjuvant properties among three formulations of "alum".
-
Disparity in the kinetics of onset of hypermutation in immunoglobulin heavy and light chains.
-
Display of cell surface sites for fibronectin assembly is modulated by cell adherence to (1)F3 and C-terminal modules of fibronectin.
-
Disrupted Blood-Retina Lysophosphatidylcholine Transport Impairs Photoreceptor Health But Not Visual Signal Transduction.
-
Disrupted Neuroglial Metabolic Coupling after Peripheral Surgery.
-
Disrupted gonadogenesis and male-to-female sex reversal in Pod1 knockout mice.
-
Disrupted iron homeostasis causes dopaminergic neurodegeneration in mice.
-
Disrupted junctional membrane complexes and hyperactive ryanodine receptors after acute junctophilin knockdown in mice.
-
Disrupted metabolic signatures in amniotic fluid associated with increased risk of intestinal inflammation in cesarean section offspring.
-
Disrupted motor learning and long-term synaptic plasticity in mice lacking NMDAR1 in the striatum.
-
Disrupted signaling and inhibited regeneration in obese mice with fatty livers: implications for nonalcoholic fatty liver disease pathophysiology.
-
Disrupting the ciliary gradient of active Arl3 affects rod photoreceptor nuclear migration.
-
Disruption at the PTCHD1 Locus on Xp22.11 in Autism spectrum disorder and intellectual disability.
-
Disruption of Acetyl-Lysine Turnover in Muscle Mitochondria Promotes Insulin Resistance and Redox Stress without Overt Respiratory Dysfunction.
-
Disruption of Arp2/3 results in asymmetric structural plasticity of dendritic spines and progressive synaptic and behavioral abnormalities.
-
Disruption of ErbB receptor signaling in adult non-myelinating Schwann cells causes progressive sensory loss.
-
Disruption of Fgf13 causes synaptic excitatory-inhibitory imbalance and genetic epilepsy and febrile seizures plus.
-
Disruption of Gen1 Causes Congenital Anomalies of the Kidney and Urinary Tract in Mice.
-
Disruption of Glucagon-Like Peptide 1 Signaling in Sim1 Neurons Reduces Physiological and Behavioral Reactivity to Acute and Chronic Stress.
-
Disruption of Gpr45 causes reduced hypothalamic POMC expression and obesity.
-
Disruption of Mekk2 in mice reveals an unexpected role for MEKK2 in modulating T-cell receptor signal transduction.
-
Disruption of PAX6 function in mice homozygous for the Pax6Sey-1Neu mutation produces abnormalities in the early development and regionalization of the diencephalon.
-
Disruption of STIM1-mediated Ca2+ sensing and energy metabolism in adult skeletal muscle compromises exercise tolerance, proteostasis, and lean mass.
-
Disruption of TrkB-mediated phospholipase Cgamma signaling inhibits limbic epileptogenesis.
-
Disruption of a nonribosomal peptide synthetase in Aspergillus fumigatus eliminates gliotoxin production.
-
Disruption of arterial perivascular drainage of amyloid-β from the brains of mice expressing the human APOE ε4 allele.
-
Disruption of diacylglycerol metabolism impairs the induction of T cell anergy.
-
Disruption of dystroglycan-laminin interactions modulates water uptake by astrocytes.
-
Disruption of intrathymic CD4-Ia interactions on immature CD4+CD8+ thymocytes results in diminished TCR expression on mature CD8+ T cell progeny.
-
Disruption of leptin signaling contributes to cardiac hypertrophy independently of body weight in mice.
-
Disruption of mindin exacerbates cardiac hypertrophy and fibrosis.
-
Disruption of mitotic arrest precedes precocious differentiation and transdifferentiation of pregranulosa cells in the perinatal Wnt4 mutant ovary.
-
Disruption of testis cords by cyclopamine or forskolin reveals independent cellular pathways in testis organogenesis.
-
Disruption of the Ang II type 1 receptor promotes longevity in mice.
-
Disruption of the expression of the proprotein convertase PC7 reduces BDNF production and affects learning and memory in mice.
-
Disruption of the gene encoding the mitogen-regulated translational modulator PHAS-I in mice.
-
Disruption of the mouse Rce1 gene results in defective Ras processing and mislocalization of Ras within cells.
-
Disruption of the mouse oestrogen receptor gene: resulting phenotypes and experimental findings.
-
Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production.
-
Disruption of the β1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner.
-
Disruption of wave-associated Rac GTPase-activating protein (Wrp) leads to abnormal adult neural progenitor migration associated with hydrocephalus.
-
Dissecting the Functional Significance of DNA Polymerase Mutations in Cancer.
-
Dissecting the in vivo metabolic potential of two human gut acetogens.
-
Dissection of a quantitative trait locus for PR interval duration identifies Tnni3k as a novel modulator of cardiac conduction.
-
Dissection of a type I interferon pathway in controlling bacterial intracellular infection in mice.
-
Dissociation between vasospasm and functional improvement in a murine model of subarachnoid hemorrhage.
-
Dissociation of frontotemporal dementia-related deficits and neuroinflammation in progranulin haploinsufficient mice.
-
Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver.
-
Distinct CD4+ helper T cells involved in primary and secondary responses to infection.
-
Distinct IL-2 receptor signaling pattern in CD4+CD25+ regulatory T cells.
-
Distinct Kinase-Independent Role of RIPK3 in CD11c+ Mononuclear Phagocytes in Cytokine-Induced Tissue Repair.
-
Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons.
-
Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism.
-
Distinct Roles of Glutamine Metabolism in Benign and Malignant Cartilage Tumors With IDH Mutations.
-
Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.
-
Distinct and overlapping sarcoma subtypes initiated from muscle stem and progenitor cells.
-
Distinct ankyrin isoforms at neuron cell bodies and nodes of Ranvier resolved using erythrocyte ankyrin-deficient mice.
-
Distinct behavioural and network correlates of two interneuron types in prefrontal cortex.
-
Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation.
-
Distinct contracted conformations of the Tcra/Tcrd locus during Tcra and Tcrd recombination.
-
Distinct cortical and striatal actions of a β-arrestin-biased dopamine D2 receptor ligand reveal unique antipsychotic-like properties.
-
Distinct effects of tafazzin deletion in differentiated and undifferentiated mitochondria.
-
Distinct electric potentials in soma and neurite membranes.
-
Distinct function of estrogen receptor α in smooth muscle and fibroblast cells in prostate development.
-
Distinct functional properties of murine perinatal and adult adipose progenitor subpopulations.
-
Distinct gene expression phenotypes of cells lacking Rb and Rb family members.
-
Distinct gene expression profiles in adult mouse heart following targeted MAP kinase activation.
-
Distinct gene expression profiles of acute myeloid/T-lymphoid leukemia with silenced CEBPA and mutations in NOTCH1.
-
Distinct granuloma responses in C57BL/6J and BALB/cByJ mice in response to pristane.
-
Distinct hematopoietic progenitor compartments are delineated by the expression of aldehyde dehydrogenase and CD34.
-
Distinct maturation profiles of perisomatic and dendritic targeting GABAergic interneurons in the mouse primary visual cortex during the critical period of ocular dominance plasticity.
-
Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm.
-
Distinct mouse coronary anatomy and myocardial infarction consequent to ligation.
-
Distinct nuclear proteins competing for an overlapping sequence of cyclic adenosine monophosphate and negative regulatory elements regulate tissue-specific mouse renin gene expression.
-
Distinct patterns of glycosylation of colligin, a collagen-binding glycoprotein, and SPARC (osteonectin), a secreted Ca2+-binding glycoprotein. Evidence for the localisation of colligin in the endoplasmic reticulum.
-
Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding.
-
Distinct properties and advantages of a novel peroxisome proliferator-activated protein [gamma] selective modulator.
-
Distinct properties of cell-type-specific and shared transcription factor binding sites.
-
Distinct recruitment of feedforward and recurrent pathways across higher-order areas of mouse visual cortex.
-
Distinct requirements for Ras oncogenesis in human versus mouse cells.
-
Distinct requirements for extra-embryonic and embryonic bone morphogenetic protein 4 in the formation of the node and primitive streak and coordination of left-right asymmetry in the mouse.
-
Distinct roles for the kidney and systemic tissues in blood pressure regulation by the renin-angiotensin system.
-
Distinct roles of E2F proteins in vascular smooth muscle cell proliferation and intimal hyperplasia.
-
Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain.
-
Distinct routes to metastasis: plasticity-dependent and plasticity-independent pathways.
-
Distinct single amino acid replacements in the control of virulence regulator protein differentially impact streptococcal pathogenesis.
-
Distinct stress responses of two functional laccases in Cryptococcus neoformans are revealed in the absence of the thiol-specific antioxidant Tsa1.
-
Distinctions in the specificity of E2F function revealed by gene expression signatures.
-
Distinctive adaptive response to repeated exposure to hydrogen peroxide associated with upregulation of DNA repair genes and cell cycle arrest.
-
Distinctive patterns of hyperplasia in transgenic mice with mouse mammary tumor virus transforming growth factor-alpha. Characterization of mammary gland and skin proliferations.
-
Distribution of amyloid precursor protein and amyloid-beta in ocular hypertensive C57BL/6 mouse eyes.
-
Distribution of binding sites for thromboxane A2 in the mouse kidney.
-
Distribution of expression of 2AR (osteopontin) in the embryonic mouse inner ear revealed by in situ hybridisation.
-
Distribution of the tight junction proteins ZO-1, occludin, and claudin-4, -8, and -12 in bladder epithelium.
-
Distribution of, and immune response to, chicken anti-alpha Gal immunoglobulin Y antibodies in wild-type and alpha Gal knockout mice.
-
Disulfide bond requirements for active Wnt ligands.
-
Disulfiram is a direct and potent inhibitor of human O6-methylguanine-DNA methyltransferase (MGMT) in brain tumor cells and mouse brain and markedly increases the alkylating DNA damage.
-
Diurnal torpidity in the California pocket mouse.
-
Diurnal variations in the toxicity and tissue levels of spermidine in mice.
-
Divalent cation activation of galactosyltransferase in native mammary Golgi vesicles.
-
Divalent metal transporter 1 regulates iron-mediated ROS and pancreatic β cell fate in response to cytokines.
-
Divergent Roles of Epithelium-Derived Alarmins in Notch Signaling-Deficient Skin.
-
Divergent functions of angiotensin II receptor isoforms in the brain.
-
Divergent pathways mediate the induction of ANF transgenes in neonatal and hypertrophic ventricular myocardium.
-
Divergent regulation of functionally distinct γ-tubulin complexes during differentiation.
-
Divergent roles for RalA and RalB in malignant growth of human pancreatic carcinoma cells.
-
Divergent vascular mechanisms downstream of Sry establish the arterial system in the XY gonad.
-
Diverse endogenous light chains contribute to basement membrane reactivity in nonautoimmune mice transgenic for an anti-laminin Ig heavy chain.
-
Diverse gap junctions modulate distinct mechanisms for fiber cell formation during lens development and cataractogenesis.
-
Diverse genetic-driven immune landscapes dictate tumor progression through distinct mechanisms.
-
Diverse inflammatory responses in transgenic mouse models of Alzheimer's disease and the effect of immunotherapy on these responses.
-
Diversity-oriented synthesis yields novel multistage antimalarial inhibitors.
-
Division of labour between Myc and G1 cyclins in cell cycle commitment and pace control.
-
Dlg5 regulates dendritic spine formation and synaptogenesis by controlling subcellular N-cadherin localization.
-
Dll4 Inhibition plus Aflibercept Markedly Reduces Ovarian Tumor Growth.
-
Do Adipocytes Emerge from Mural Progenitors?
-
Do Surface Porosity and Pore Size Influence Mechanical Properties and Cellular Response to PEEK?
-
Do germinal centers have a role in the generation of lymphomas?
-
Docetaxel enhances tumor radioresponse in vivo.
-
Domains of the adenovirus E1A protein required for oncogenic activity are also required for dissociation of E2F transcription factor complexes.
-
Dominant-negative androgen receptor inhibition of intracrine androgen-dependent growth of castration-recurrent prostate cancer.
-
Dominant-negative mutants of Grb2 induced reversal of the transformed phenotypes caused by the point mutation-activated rat HER-2/Neu.
-
Donor Allospecific CD44high Central Memory T Cells Have Decreased Ability to Mediate Graft-vs.-Host Disease.
-
Donor apoptotic cell-based therapy for effective inhibition of donor-specific memory T and B cells to promote long-term allograft survival in allosensitized recipients.
-
Donor-derived regulatory B cells are important for suppression of murine sclerodermatous chronic graft-versus-host disease.
-
Donor-derived, tolerogenic dendritic cells suppress immune rejection in the indirect allosensitization-dominant setting of corneal transplantation.
-
Donor-specific CD8+ Foxp3+ T cells protect skin allografts and facilitate induction of conventional CD4+ Foxp3+ regulatory T cells.
-
Dopamine and α-synuclein dysfunction in Smad3 null mice.
-
Dopamine levels modulate the updating of tastant values.
-
Dopamine mediates vagal modulation of the immune system by electroacupuncture.
-
Dopamine neuronal transport kinetics and effects of amphetamine.
-
Dopamine suppresses osteoclast differentiation via cAMP/PKA/CREB pathway.
-
Dopamine-Dependent Sensitization of Rod Bipolar Cells by GABA Is Conveyed through Wide-Field Amacrine Cells.
-
Dopamine-independent locomotor actions of amphetamines in a novel acute mouse model of Parkinson disease.
-
Dopaminergic Control of Inflammation and Glycemia in Sepsis and Diabetes.
-
Dopaminergic control of corticostriatal long-term synaptic depression in medium spiny neurons is mediated by cholinergic interneurons.
-
Dopaminergic control of sleep-wake states.
-
Dopaminergic neurodegeneration induced by Parkinson's disease-linked G2019S LRRK2 is dependent on kinase and GTPase activity.
-
Dopaminergic supersensitivity in G protein-coupled receptor kinase 6-deficient mice.
-
Dormant breast cancer micrometastases reside in specific bone marrow niches that regulate their transit to and from bone.
-
Dorsalizing and neuralizing properties of Xdsh, a maternally expressed Xenopus homolog of dishevelled.
-
Dosage-dependent requirements of Magoh for cortical interneuron generation and survival.
-
Dose-dependent effect of melatonin on life span and spontaneous tumor incidence in female SHR mice.
-
Dose-dependent expression of claudin-5 is a modifying factor in schizophrenia.
-
Dosimetry and radiographic analysis of 131I-labeled anti-tenascin 81C6 murine monoclonal antibody in newly diagnosed patients with malignant gliomas: a phase II study.
-
Double genetic modification of adenovirus fiber with RGD polylysine motifs significantly enhances gene transfer to isolated human pancreatic islets.
-
Double-illumination photoacoustic microscopy.
-
Down regulation of macrophage mannose/N-acetylglucosamine receptors by elevated glucose concentrations.
-
Down-regulation of Bmp/Smad signaling by Tmprss6 is required for maintenance of systemic iron homeostasis.
-
Down-regulation of MHC class I antigen presentation by HCMV; lessons for tumor immunology.
-
Down-regulation of cathepsin B expression impairs the invasive and tumorigenic potential of human glioblastoma cells.
-
Down-regulation of statin, a nonproliferation-specific nuclear protein, and up-regulation of c-myc after initiation of programmed cell death in mouse fibroblasts.
-
Down-regulation of the orphan nuclear receptor ROR gamma t is essential for T lymphocyte maturation.
-
Downregulation of NR3A-containing NMDARs is required for synapse maturation and memory consolidation.
-
Downregulation of T cell receptor expression by CD8(+) lymphocytes in kidney allografts.
-
Downregulation of adipose glutathione S-transferase A4 leads to increased protein carbonylation, oxidative stress, and mitochondrial dysfunction.
-
Downregulation of carnitine acyl-carnitine translocase by miRNAs 132 and 212 amplifies glucose-stimulated insulin secretion.
-
Downregulation of hepatic betaine:homocysteine methyltransferase (BHMT) expression in taurine-deficient mice is reversed by taurine supplementation in vivo.
-
Downregulation of microglial activation by apolipoprotein E and apoE-mimetic peptides.
-
Doxorubicin-conjugated chimeric polypeptide nanoparticles that respond to mild hyperthermia.
-
Doxorubicin-conjugated polypeptide nanoparticles inhibit metastasis in two murine models of carcinoma.
-
Drd1a-tdTomato BAC transgenic mice for simultaneous visualization of medium spiny neurons in the direct and indirect pathways of the basal ganglia.
-
Drebrin attenuates atherosclerosis by limiting smooth muscle cell transdifferentiation.
-
Drebrin, an actin-binding protein, is required for lens morphogenesis and growth.
-
Dromedary camel nanobodies broadly neutralize SARS-CoV-2 variants.
-
Drug targeting using thermally responsive polymers and local hyperthermia.
-
Drug-Resistant Epimutants Exhibit Organ-Specific Stability and Induction during Murine Infections Caused by the Human Fungal Pathogen Mucor circinelloides.
-
Drugs derived from cannabinoids. 2. Basic esters of nitrogen and carbocyclic analogs.
-
Drugs derived from cannabinoids. 4. Effect of alkyl substitution in sulfur and carbocyclic analogs.
-
Dual Metronomic Chemotherapy with Nab-Paclitaxel and Topotecan Has Potent Antiangiogenic Activity in Ovarian Cancer.
-
Dual Role of Epidermal Growth Factor Receptor in Liver Injury and Regeneration after Acetaminophen Overdose in Mice.
-
Dual inhibition of beta-adrenergic and angiotensin II receptors by a single antagonist: a functional role for receptor-receptor interaction in vivo.
-
Dual inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation by AEE788 reduces growth and metastasis of human colon carcinoma in an orthotopic nude mouse model.
-
Dual labeling of the fibronectin matrix and actin cytoskeleton with green fluorescent protein variants.
-
Dual modulation of cell survival and cell death by beta(2)-adrenergic signaling in adult mouse cardiac myocytes.
-
Dual protein farnesyltransferase-geranylgeranyltransferase-I inhibitors as potential cancer chemotherapeutic agents.
-
Dual role of the exocyst in AMPA receptor targeting and insertion into the postsynaptic membrane.
-
Dual roles of modulatory calcineurin-interacting protein 1 in cardiac hypertrophy.
-
Dual source hybrid spectral micro-CT using an energy-integrating and a photon-counting detector.
-
Dual stem loops within the poliovirus internal ribosomal entry site control neurovirulence.
-
Dual-Energy CT Imaging of Tumor Liposome Delivery After Gold Nanoparticle-Augmented Radiation Therapy.
-
Dual-axis illumination for virtually augmenting the detection view of optical-resolution photoacoustic microscopy
-
Dual-energy computed tomography imaging of atherosclerotic plaques in a mouse model using a liposomal-iodine nanoparticle contrast agent.
-
Dual-energy micro-CT functional imaging of primary lung cancer in mice using gold and iodine nanoparticle contrast agents: a validation study.
-
Dual-energy micro-CT of the rodent lung.
-
Dual-energy micro-computed tomography imaging of radiation-induced vascular changes in primary mouse sarcomas.
-
Dual-mode IVUS transducer for image-guided brain therapy: preliminary experiments.
-
Dual-targeted hybrid nanoparticles of synergistic drugs for treating lung metastases of triple negative breast cancer in mice.
-
Dual-wavelength ratiometric fluorescence measurement of the membrane dipole potential.
-
Duality of innate stress responses in cardiac injury, repair, and remodeling.
-
Dusp3 and Psme3 are associated with murine susceptibility to Staphylococcus aureus infection and human sepsis.
-
Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2.
-
Dynamic actin polymerization drives T cell receptor-induced spreading: a role for the signal transduction adaptor LAT.
-
Dynamic and redundant regulation of LRRK2 and LRRK1 expression.
-
Dynamic antibody-binding properties in the pathogenesis of HIT.
-
Dynamic changes in the dendritic geometry of individual neurons visualized over periods of up to three months in the superior cervical ganglion of living mice.
-
Dynamic contrast-enhanced MR microscopy identifies regions of therapeutic response in a preclinical model of colorectal adenocarcinoma.
-
Dynamic contrast-enhanced quantitative susceptibility mapping with ultrashort echo time MRI for evaluating renal function.
-
Dynamic denitrosylation via S-nitrosoglutathione reductase regulates cardiovascular function.
-
Dynamic exchange at regulatory elements during chromatin remodeling underlies assisted loading mechanism.
-
Dynamic fractal signature dissimilarity analysis for therapeutic response assessment using dynamic contrast-enhanced MRI.
-
Dynamic intercellular redistribution of HIT antigen modulates heparin-induced thrombocytopenia.
-
Dynamic mRNA Transport and Local Translation in Radial Glial Progenitors of the Developing Brain.
-
Dynamic microRNA gene transcription and processing during T cell development.
-
Dynamic regulation of sarcoplasmic reticulum Ca(2+) stores by stromal interaction molecule 1 and sarcolipin during muscle differentiation.
-
Dynamic reorganization of striatal circuits during the acquisition and consolidation of a skill.
-
Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration.
-
Dynamin-related Irgm proteins modulate LPS-induced caspase-11 activation and septic shock.
-
Dysfunctional T cell metabolism in the tumor microenvironment.
-
Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer.
-
Dysregulated activation of fetal liver programme in acute liver failure.
-
Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD.
-
Dysregulation of C/EBPalpha by mutant Huntingtin causes the urea cycle deficiency in Huntington's disease.
-
Dysregulation of STAT3 signaling is associated with endplate-oriented herniations of the intervertebral disc in Adgrg6 mutant mice.
-
Dysregulation of ectonucleotidase-mediated extracellular adenosine during postmenopausal bone loss.
-
Dysregulation of hedgehog signalling predisposes to synovial chondromatosis.
-
Dysregulation of mitochondrial dynamics proteins are a targetable feature of human tumors.
-
Dysregulation of multiple facets of glycogen metabolism in a murine model of Pompe disease.
-
Dysregulation of the ESRP2-NF2-YAP/TAZ axis promotes hepatobiliary carcinogenesis in non-alcoholic fatty liver disease.
-
Dysregulation of the Hedgehog pathway in human hepatocarcinogenesis.
-
Dysregulation of the Synaptic Cytoskeleton in the PFC Drives Neural Circuit Pathology, Leading to Social Dysfunction.
-
Dysregulation of the mTOR pathway secondary to mutations or a hostile microenvironment contributes to cancer and poor wound healing.
-
Déjà Vu But New: Using T Cells to Deplete B Cells to Treat Lupus.
-
E protein transcription factors are required for the development of CD4(+) lineage T cells.
-
E proteins are required to activate germline transcription of the TCR Vbeta8.2 gene.
-
E-cadherin is involved in the intrahepatic metastasis of hepatocellular carcinoma.
-
E-cadherin polarity is determined by a multifunction motif mediating lateral membrane retention through ankyrin-G and apical-lateral transcytosis through clathrin.
-
E-prostanoid-3 receptors mediate the proinflammatory actions of prostaglandin E2 in acute cutaneous inflammation.
-
E-protein-regulated expression of CXCR4 adheres preselection thymocytes to the thymic cortex.
-
E2-induced degradation of uterine insulin receptor substrate-2: requirement for an IGF-I-stimulated, proteasome-dependent pathway.
-
E2A and HEB are required to block thymocyte proliferation prior to pre-TCR expression.
-
E2A and IRF-4/Pip promote chromatin modification and transcription of the immunoglobulin kappa locus in pre-B cells.
-
E2A promotes the survival of precursor and mature B lymphocytes.
-
E3 ubiquitin ligase TRIM32 negatively regulates tumor suppressor p53 to promote tumorigenesis.
-
EAG2 potassium channel with evolutionarily conserved function as a brain tumor target.
-
EBV latent membrane protein 2A induces autoreactive B cell activation and TLR hypersensitivity.
-
EBV-positive diffuse large B-cell lymphoma of the elderly: 2016 update on diagnosis, risk-stratification, and management.
-
ECDI-fixed allogeneic splenocytes induce donor-specific tolerance for long-term survival of islet transplants via two distinct mechanisms.
-
EGF promotes mammalian cell growth by suppressing cellular senescence.
-
EGFR in enterocytes & endothelium and HIF1α in enterocytes are dispensable for massive small bowel resection induced angiogenesis.
-
EGFR-upregulated LIFR promotes SUCLG2-dependent castration resistance and neuroendocrine differentiation of prostate cancer.
-
EGFRvIII and c-Met pathway inhibitors synergize against PTEN-null/EGFRvIII+ glioblastoma xenografts.
-
EGFRvIII mCAR-modified T-cell therapy cures mice with established intracerebral glioma and generates host immunity against tumor-antigen loss.
-
EGFRvIII-specific chimeric antigen receptor T cells migrate to and kill tumor deposits infiltrating the brain parenchyma in an invasive xenograft model of glioblastoma.
-
EGFRvIII-targeted immunotoxin induces antitumor immunity that is inhibited in the absence of CD4+ and CD8+ T cells.
-
EIF4A3 deficient human iPSCs and mouse models demonstrate neural crest defects that underlie Richieri-Costa-Pereira syndrome.
-
EJ-Ras inhibits phospholipase C gamma 1 but not actin polymerization induced by platelet-derived growth factor-BB via phosphatidylinositol 3-kinase.
-
EL-4 metastases in spleen and bone marrow suppress the NK activity generated in these organs.
-
ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation.
-
ELF3 is a repressor of androgen receptor action in prostate cancer cells.
-
ELKS1 controls mast cell degranulation by regulating the transcription of Stxbp2 and Syntaxin 4 via Kdm2b stabilization.
-
ELR+ CXC chemokines and oncogenic Ras-mediated tumorigenesis.
-
ENU mutagenesis identifies mice with cardiac fibrosis and hepatic steatosis caused by a mutation in the mitochondrial trifunctional protein beta-subunit.
-
ENU mutagenesis identifies mice with mitochondrial branched-chain aminotransferase deficiency resembling human maple syrup urine disease.
-
ENaC- and CFTR-dependent ion and fluid transport in mammary epithelia.
-
EP24.15 interacts with the angiotensin II type I receptor and bradykinin B2 receptor.
-
EPCR knockout: inflaming the discussion.
-
ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis.
-
ER stress modulates cellular metabolism.
-
ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression.
-
ERAAP synergizes with MHC class I molecules to make the final cut in the antigenic peptide precursors in the endoplasmic reticulum.
-
ERG responses and microarray analysis of gene expression in a multifactorial murine model of age-related retinal degeneration.
-
ERRgamma regulates cardiac, gastric, and renal potassium homeostasis.
-
ERα Signaling Increased IL-17A Production in Th17 Cells by Upregulating IL-23R Expression, Mitochondrial Respiration, and Proliferation.
-
ETC-159, an Upstream Wnt inhibitor, Induces Tumour Necrosis via Modulation of Angiogenesis in Osteosarcoma.
-
ETS transcription factors regulate an enhancer activity in the third intron of TNF-alpha.
-
EXT1 regulates chondrocyte proliferation and differentiation during endochondral bone development.
-
Early B-cell activation after West Nile virus infection requires alpha/beta interferon but not antigen receptor signaling.
-
Early Odorant Exposure Increases the Number of Mitral and Tufted Cells Associated with a Single Glomerulus.
-
Early adaptive chromatin remodeling events precede pathologic phenotypes and are reinforced in the failing heart.
-
Early detection and measurement of urothelial tumors in mice.
-
Early detection of cerebrovascular pathology and protective antiviral immunity by MRI.
-
Early detection of pemetrexed-induced inhibition of thymidylate synthase in non-small cell lung cancer with FLT-PET imaging.
-
Early embryonic lethality of mice with disrupted transcription cofactor PIMT/NCOA6IP/Tgs1 gene.
-
Early fetal hypoxia leads to growth restriction and myocardial thinning.
-
Early forming label-retaining muscle stem cells require p27kip1 for maintenance of the primitive state.
-
Early growth response 1 and NF-ATc1 act in concert to promote thymocyte development beyond the beta-selection checkpoint.
-
Early induction of hepatic deiodinase type 1 inhibits hepatosteatosis during NAFLD progression.
-
Early induction of oxidative stress in mouse model of Alzheimer disease with reduced mitochondrial superoxide dismutase activity.
-
Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.
-
Early neutralizing IgG response to Chikungunya virus in infected patients targets a dominant linear epitope on the E2 glycoprotein.
-
Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD.
-
Early, sustained efficacy of adeno-associated virus vector-mediated gene therapy in glycogen storage disease type Ia.
-
Early-Life Intranasal Colonization with Nontypeable Haemophilus influenzae Exacerbates Juvenile Airway Disease in Mice.
-
Eccentric rehabilitation induces white matter plasticity and sensorimotor recovery in chronic spinal cord injury.
-
Ecdysone-inducible gene expression in mammalian cells and transgenic mice.
-
Echocardiographically detected myocardial infarction in the mouse.
-
Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis.
-
Ectopic expression of Hel-N1, an RNA-binding protein, increases glucose transporter (GLUT1) expression in 3T3-L1 adipocytes.
-
Ectopic expression of interferon regulatory factor-1 promotes human breast cancer cell death and results in reduced expression of survivin.
-
Ectopic lipid deposition and the metabolic profile of skeletal muscle in ovariectomized mice.
-
Ectopic myelinating oligodendrocytes in the dorsal spinal cord as a consequence of altered semaphorin 6D signaling inhibit synapse formation.
-
Ectopic synaptogenesis in the mammalian retina caused by rod photoreceptor-specific mutations.
-
Editing out five Serpina1 paralogs to create a mouse model of genetic emphysema.
-
Effect of Anti-C5a Therapy in a Murine Model of Early/Intermediate Dry Age-Related Macular Degeneration.
-
Effect of CXCL-1/KC production in high risk vascularized corneal allografts on T cell recruitment and graft rejection.
-
Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice.
-
Effect of Human Genetic Variability on Gene Expression in Dorsal Root Ganglia and Association with Pain Phenotypes.
-
Effect of IGFBP-3 on IGF- and IGF-analogue-induced insulin-like growth factor-I receptor (IGFIR) signalling.
-
Effect of Steel factor and leukaemia inhibitory factor on murine primordial germ cells in culture.
-
Effect of a metalloporphyrin antioxidant (MnTE-2-PyP) on the response of a mouse prostate cancer model to radiation.
-
Effect of a purified diet on dystrophic cardiac calcinosis in mice.
-
Effect of adriamycin and Corynebacterium parvum in tumor-bearing mice: modulation of response to sheep red blood cells.
-
Effect of aerobic exercise on tumor physiology in an animal model of human breast cancer.
-
Effect of anti-CD4 antibody treatment on inflammatory arthritis in MRL-lpr/lpr mice.
-
Effect of basic fibroblast growth factor on angiogenesis and growth of isografted bone: quantitative in vitro-in vivo analysis in mice.
-
Effect of bismuth salts on systemic and mucosal immune responses to orally administered cholera toxin.
-
Effect of chemotherapy on uptake of alkali metals by experimental tumors.
-
Effect of cocaine and cocaine congeners on veratridine-induced depolarization in mouse cerebrocortical synaptoneurosomes.
-
Effect of compressive force on unbinding specific protein-ligand complexes with force spectroscopy.
-
Effect of cyclic nucleotides on the induction of ornithine decarboxylase in BHK cells by serum and insulin.
-
Effect of cyclic stretch on beta1D-integrin expression and activation of FAK and RhoA.
-
Effect of cyclical intermittent hypoxia on Ad5CMVCre induced solitary lung cancer progression and spontaneous metastases in the KrasG12D+; p53fl/fl; myristolated p110fl/fl ROSA-gfp mouse.
-
Effect of cytofectins on the immune response of murine macrophages to mammalian DNA.
-
Effect of delta-sleep inducing peptide-containing preparation Deltaran on biomarkers of aging, life span and spontaneous tumor incidence in female SHR mice.
-
Effect of desiccating environmental stress versus systemic muscarinic AChR blockade on dry eye immunopathogenesis.
-
Effect of drug release kinetics on nanoparticle therapeutic efficacy and toxicity.
-
Effect of endotoxin and alum adjuvant vaccine on peanut allergy.
-
Effect of ethanol on tumor necrosis factor signaling during liver regeneration.
-
Effect of exposure to light-at-night on life span and spontaneous carcinogenesis in female CBA mice.
-
Effect of fatty acids on insulin release: role of chain length and degree of unsaturation.
-
Effect of flaxseed supplementation on prostatic carcinoma in transgenic mice.
-
Effect of host microenvironment on the microcirculation of human colon adenocarcinoma.
-
Effect of immunosuppressants on T-cell subsets observed in vivo using carboxy-fluorescein diacetate succinimidyl ester labeling.
-
Effect of interferon on murine leukemia virus infection. II. Synthesis of viral components in exogenous infection.
-
Effect of interferon-gamma and human alpha 2-macroglobulin on peritoneal macrophage morphology and Ia antigen expression.
-
Effect of interleukin-1β on the expression of actin isoforms in cultured mouse astroglia.
-
Effect of intermittent fasting on prostate cancer tumor growth in a mouse model.
-
Effect of intraocular gamma-interferon on immunoregulatory properties of iris and ciliary body cells.
-
Effect of irradiation on cytokine production, MHC antigen expression, and vaccine potential of interleukin-2 and interferon-gamma gene-modified melanoma cells.
-
Effect of isocaloric low fat diet on prostate cancer xenograft progression in a hormone deprivation model.
-
Effect of microRNA modulation on bioartificial muscle function.
-
Effect of nandrolone decanoate administration on recovery from bupivacaine-induced muscle injury.
-
Effect of neuronol on lifespan and development of spontaneous tumors in SAMP-1 mice with genetically accelerated aging.
-
Effect of obesity on pulmonary inflammation induced by acute ozone exposure: role of interleukin-6.
-
Effect of oxidative stress on homer scaffolding proteins.
-
Effect of p38 MAP kinases on contractility and ischemic injury in intact heart.
-
Effect of pain management on immunization efficacy in mice.
-
Effect of pazopanib on tumor microenvironment and liposome delivery.
-
Effect of poly(ethylene glycol) diacrylate concentration on network properties and in vivo response of poly(β-amino ester) networks.
-
Effect of preexposure to ultrafine carbon black on respiratory syncytial virus infection in mice.
-
Effect of propranolol as antiadhesive therapy in sickle cell disease.
-
Effect of rapamycin alone and in combination with antiangiogenesis therapy in an orthotopic model of human pancreatic cancer.
-
Effect of receptor number on desensitization of the mouse thromboxane receptor.
-
Effect of sera from myasthenia gravis patients on acetylcholine receptors in myotube cultures.
-
Effect of sex on the induction of anti-DNA antibodies in normal mice immunized with bacterial DNA.
-
Effect of sulfur substitution for the noncarbonyl oxygen in hemicholinium-3 and acetyl-seco-hemicholinium-3. Synthesis, biological activity, and structure-toxicity relationships.
-
Effect of surface topography on in vitro osteoblast function and mechanical performance of 3D printed titanium.
-
Effect of synthetic thymic and pineal peptides on biomarkers of ageing, survival and spontaneous tumour incidence in female CBA mice.
-
Effect of temperature on blood flow and hypoxic fraction in a murine fibrosarcoma.
-
Effect of the laccase gene CNLAC1, on virulence of Cryptococcus neoformans.
-
Effect of the monoamine oxidase inhibitors clorgyline and pargyline on the hyperphagia of obese mice.
-
Effect of the nitric oxide donor V-PYRRO/NO on portal pressure and sinusoidal dynamics in normal and cirrhotic mice.
-
Effect of topical azithromycin on corneal innate immune responses.
-
Effect of transient hydronephrosis on subsequent compensatory renal growth.
-
Effect of vasoactive intestinal peptide (VIP) on cytokine production and expression of VIP receptors in thymocyte subsets.
-
Effect of virus infection on the inflammatory response. Depression of macrophage accumulation in influenza-infected mice.
-
Effect os xid on anti-DNA B-cell precursors.
-
Effective Treatment of Human Breast Carcinoma Xenografts with Single-Dose 211
At-Labeled Anti-HER2 Single-Domain Antibody Fragment.
-
Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor.
-
Effective antibody therapy in herpes simplex virus ocular infection. Characterization of recipient immune response.
-
Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism.
-
Effective induction of protective systemic immunity with nasally administered vaccines adjuvanted with IL-1.
-
Effective treatment of experimental DU-145 prostate cancers with targeted cytotoxic somatostatin analog AN-238.
-
Effective treatment of models of multiple sclerosis by matrix metalloproteinase inhibitors.
-
Effective tumor therapy with plasmid-encoded cytokines combined with in vivo electroporation.
-
Effectiveness of combined interleukin 2 and B7.1 vaccination strategy is dependent on the sequence and order: a liposome-mediated gene therapy treatment for bladder cancer.
-
Effector T Cell Egress via Afferent Lymph Modulates Local Tissue Inflammation.
-
Effector mechanisms of cytolytically activated macrophages. II. Secretion of a cytolytic factor by activated macrophages and its relationship to secreted neutral proteases.
-
Effects and potential mechanisms of exercise training on cancer progression: a translational perspective.
-
Effects of 10-hydroxycamptothecin, delivered from locally injectable poly(lactide-co-glycolide) microspheres, in a murine human oral squamous cell carcinoma regression model.
-
Effects of Acetaminophen on Oxidant and Irritant Respiratory Tract Responses to Environmental Tobacco Smoke in Female Mice.
-
Effects of CKS-17, a synthetic retroviral envelope peptide, on cell-mediated immunity in vivo: immunosuppression, immunogenicity, and relation to immunosuppressive tumor products.
-
Effects of Cell-Based Therapy for Treating Tympanic Membrane Perforations in Mice.
-
Effects of CoA-independent transacylase inhibitors on the production of lipid inflammatory mediators.
-
Effects of HMGB1 on in vitro responses of isolated muscle fibers and functional aspects in skeletal muscles of idiopathic inflammatory myopathies.
-
Effects of HSP70.1/3 gene knockout on acute respiratory distress syndrome and the inflammatory response following sepsis.
-
Effects of Helicobacter infection on research: the case for eradication of Helicobacter from rodent research colonies.
-
Effects of IL-1 on hematopoietic progenitors after myelosuppressive chemoradiotherapy.
-
Effects of Long-Term Vagus Nerve Electrical Stimulation Therapy on Acute Cerebral Infarction and Neurological Function Recovery in Post MCAO Mice.
-
Effects of N-acetylcysteine in ozone-induced chronic obstructive pulmonary disease model.
-
Effects of Space Flight on Mouse Liver versus Kidney: Gene Pathway Analyses.
-
Effects of Y27632 on keratinocyte procurement and wound healing.
-
Effects of a block in cysteine catabolism on energy balance and fat metabolism in mice.
-
Effects of a gut pathobiont in a gnotobiotic mouse model of childhood undernutrition.
-
Effects of a manganese (III) porphyrin catalytic antioxidant in a mouse closed head injury model.
-
Effects of a novel arginine methyltransferase inhibitor on T-helper cell cytokine production.
-
Effects of acute tryptophan depletion on brain serotonin function and concentrations of dopamine and norepinephrine in C57BL/6J and BALB/cJ mice.
-
Effects of allergic airway disease on mouse adenovirus type 1 respiratory infection.
-
Effects of antifungal agents and gamma interferon on macrophage cytotoxicity for fungi and tumor cells.
-
Effects of bacterial DNA on cytokine production by (NZB/NZW)F1 mice.
-
Effects of bacterial lipopolysaccharide on the hydrolysis of phosphatidylinositol-4,5-bisphosphate in murine peritoneal macrophages.
-
Effects of calcium on ACTH stimulation of the adrenal: separation of hormone binding from adenyl cyclase activation.
-
Effects of candesartan on angiotensin II-induced renal vasoconstriction in rats and mice.
-
Effects of castration and chronic steroid treatments on hypothalamic gonadotropin-releasing hormone content and pituitary gonadotropins in male wild-type and estrogen receptor-alpha knockout mice.
-
Effects of chemically induced ovarian failure on voluntary wheel-running exercise and cardiac adaptation in mice.
-
Effects of chondroitin sulfate proteoglycan 4 (NG2/CSPG4) on soft-tissue sarcoma growth depend on tumor developmental stage.
-
Effects of chronic exposure to simulated microgravity on skeletal muscle cell proliferation and differentiation.
-
Effects of classical and atypical antipsychotic drugs on isolation-induced aggression in male mice.
-
Effects of cyclosporine on human B-cell lymphoma development in vivo.
-
Effects of glutathione or polyamine depletion on in vivo thermosensitization.
-
Effects of growth hormone and IGF-I on cardiac hypertrophy and gene expression in mice.
-
Effects of high-dose microbeam irradiation on tumor microvascular function and angiogenesis.
-
Effects of hyperthermia and irradiation on the growth of mouse melanoma tumors following immunotherapy.
-
Effects of iron deficiency anemia and its treatment on fibroblast growth factor 23 and phosphate homeostasis in women.
-
Effects of lactogen resistance and GH deficiency on mouse metabolism: pancreatic hormones, adipocytokines, and expression of adiponectin and insulin receptors.
-
Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice.
-
Effects of maternal urban particulate matter SRM 1648a exposure on birth outcomes and offspring growth in mice.
-
Effects of murine cytomegalovirus infection on the immune response to a tumor allograft.
-
Effects of myocardial infarction on the distribution and transport of nutrients and oxygen in porcine myocardium.
-
Effects of neoplasms on inflammation: depression of macrophage accumulation after tumor implantation.
-
Effects of neuronal PIK3C3/Vps34 deletion on autophagy and beyond.
-
Effects of nitric oxide releasing poly(vinyl alcohol) hydrogel dressings on dermal wound healing in diabetic mice.
-
Effects of nitrogen mustard and splenectomy on mouse bone marrow colony formation in vitro.
-
Effects of nociceptin (13-17) in pain modulation at supraspinal level in mice.
-
Effects of oral genistein in mice.
-
Effects of oxidized LDL on mononuclear phagocytes: inhibition of induction of four inflammatory cytokine gene RNAs, release of NO, and cytolysis of tumor cells.
-
Effects of oxygen on the metabolism of murine tumors using in vivo phosphorus-31 NMR.
-
Effects of pentobarbital anesthesia on the energy metabolism of murine tumors studied by in vivo 31P nuclear magnetic resonance spectroscopy.
-
Effects of periadolescent versus adult cocaine exposure on cocaine conditioned place preference and motor sensitization in mice.
-
Effects of pimozide and penfluridol on the binding and endocytosis of alpha 2-macroglobulin-CH3NH2 by mouse peritoneal macrophages.
-
Effects of progesterone and estradiol sex hormones on the release of microparticles by RAW 264.7 macrophages stimulated by Poly(I:C).
-
Effects of rate, volume, and dose of intratumoral infusion on virus dissemination in local gene delivery.
-
Effects of sazetidine-A, a selective α4β2* nicotinic receptor desensitizing agent, on body temperature regulation in mice and rats.
-
Effects of sex and genotype in human APOE-targeted replacement mice on alcohol self-administration measured with the automated IntelliCage system before and after repeated mild traumatic brain injury.
-
Effects of simvastatin on retinal structure and function of a high-fat atherogenic mouse model of thickened Bruch's membrane.
-
Effects of sodium fluoroacetate on the metabolism of N-acetylaspartate and aspartate in mouse brain.
-
Effects of spaceflight on murine skeletal muscle gene expression.
-
Effects of the kinase inhibitor sorafenib on heart, muscle, liver and plasma metabolism in vivo using non-targeted metabolomics analysis.
-
Effects of the lpr mutation on elimination and inactivation of self-reactive B cells.
-
Effects of the proteasome inhibitor PS-341 on apoptosis and angiogenesis in orthotopic human pancreatic tumor xenografts.
-
Effects of the sazetidine-a family of compounds on the body temperature in wildtype, nicotinic receptor β2-/- and α7-/- mice.
-
Effects of therapy on the 1H NMR spectrum of a human glioma line.
-
Effects of topical and subconjunctival bevacizumab in high-risk corneal transplant survival.
-
Effects of tumor growth on host defenses.
-
Effects of tumor microenvironment heterogeneity on nanoparticle disposition and efficacy in breast cancer tumor models.
-
Effects of tumor necrosis factor on viral replication and pulmonary inflammation during acute mouse adenovirus type 1 respiratory infection.
-
Effects on blood pressure and exploratory behaviour of mice lacking angiotensin II type-2 receptor.
-
Efferent synapses return to inner hair cells in the aging cochlea.
-
Efficacious Androgen Hormone Administration in Combination with Adeno-Associated Virus Vector-Mediated Gene Therapy in Female Mice with Pompe Disease.
-
Efficacy and pharmacokinetic/pharmacodynamic evaluation of the Aurora kinase A inhibitor MLN8237 against preclinical models of pediatric cancer.
-
Efficacy and pharmacokinetics of a modified acid-labile docetaxel-PRINT(®) nanoparticle formulation against non-small-cell lung cancer brain metastases.
-
Efficacy and toxicity of 9-beta-D-arabinofuranosylguanine (araG) as an agent to purge malignant T cells from murine bone marrow: application to an in vivo T-leukemia model.
-
Efficacy of APX2039 in a Rabbit Model of Cryptococcal Meningitis.
-
Efficacy of BET bromodomain inhibition in Kras-mutant non-small cell lung cancer.
-
Efficacy of Carboplatin Alone and in Combination with ABT888 in Intracranial Murine Models of BRCA-Mutated and BRCA-Wild-Type Triple-Negative Breast Cancer.
-
Efficacy of SERD/SERM Hybrid-CDK4/6 Inhibitor Combinations in Models of Endocrine Therapy-Resistant Breast Cancer.
-
Efficacy of an abbreviated induction regimen of amphotericin B deoxycholate for cryptococcal meningoencephalitis: 3 days of therapy is equivalent to 14 days.
-
Efficacy of an adeno-associated virus 8-pseudotyped vector in glycogen storage disease type II.
-
Efficacy of antisense morpholino oligomer targeted to c-myc in prostate cancer xenograft murine model and a Phase I safety study in humans.
-
Efficacy of auranofin as an inhibitor of desmoid progression.
-
Efficacy of colistin-impregnated beads to prevent multidrug-resistant A. baumannii implant-associated osteomyelitis.
-
Efficacy of gene therapy for a prototypical lysosomal storage disease (GSD-II) is critically dependent on vector dose, transgene promoter, and the tissues targeted for vector transduction.
-
Efficacy of helper-dependent adenovirus vector-mediated gene therapy in murine glycogen storage disease type Ia.
-
Efficacy of liposomes and hyperthermia in a human tumor xenograft model: importance of triggered drug release.
-
Efficacy of multiple administrations of a recombinant adenovirus expressing wild-type p53 in an immune-competent mouse tumor model.
-
Efficacy of topoisomerase I inhibitors, topotecan and irinotecan, administered at low dose levels in protracted schedules to mice bearing xenografts of human tumors.
-
Efficient CD4Cre-Mediated Conditional KRas Expression in Alveolar Macrophages and Alveolar Epithelial Cells Causes Fatal Hyperproliferative Pneumonitis.
-
Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced bone marrow.
-
Efficient cross-priming of antiviral CD8+ T cells by antigen donor cells is GRP94 independent.
-
Efficient dendritic cell priming of T lymphocytes depends on the extracellular matrix protein mindin.
-
Efficient intratracheal delivery of airway epithelial cells in mice and pigs.
-
Efficient lymphocyte migration across high endothelial venules of mouse Peyer's patches requires overlapping expression of L-selectin and beta7 integrin.
-
Efficient purification and metabolite analysis of radiotracers using high-performance liquid chromatography and on-line solid-phase extraction.
-
Efficient quantification of afferent cochlear ultrastructure using design-based stereology.
-
Efficient transdifferentiation of human dermal fibroblasts into skeletal muscle.
-
Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice.
-
Ehd4 is required to attain normal prepubertal testis size but dispensable for fertility in male mice.
-
Ehrlichiosis in children.
-
Ejaculatory abnormalities in mice with targeted disruption of the gene for heme oxygenase-2.
-
Elastic hydrogel as a sensor for detection of mechanical stress generated by single cells grown in three-dimensional environment.
-
Elastomeric polyamide biomaterials with stereochemically tuneable mechanical properties and shape memory.
-
Electric field-mediated transport of plasmid DNA in tumor interstitium in vivo.
-
Electric fields in tumors exposed to external voltage sources: implication for electric field-mediated drug and gene delivery.
-
Electrical coupling mediates tunable low-frequency oscillations and resonance in the cerebellar Golgi cell network.
-
Electromobility of plasmid DNA in tumor tissues during electric field-mediated gene delivery.
-
Electron transport complex I is required for CD8+ T cell function.
-
Electrophoretic analysis of four high molecular weight sialoglycoproteins produced by metastatic human colon carcinoma cells.
-
Electrophysiological and biochemical characteristics of Gymnodinium breve toxins.
-
Electrotonic influences on action potential duration dispersion in small hearts: a simulation study.
-
Elementary Ca2+ signals through endothelial TRPV4 channels regulate vascular function.
-
Elevated DNA polymerase alpha, DNA polymerase beta, and DNA topoisomerase II in a melphalan-resistant rhabdomyosarcoma xenograft that is cross-resistant to nitrosoureas and topotecan.
-
Elevated Urinary Rab10 Phosphorylation in Idiopathic Parkinson Disease.
-
Elevated beta-cell calmodulin produces a unique insulin secretory defect in transgenic mice.
-
Elevated blood pressure and enhanced myocardial contractility in mice with severe IGF-1 deficiency.
-
Elevated chemokine responses are maintained in lungs after clearance of viral infection.
-
Elevated expression of PCGEM1, a prostate-specific gene with cell growth-promoting function, is associated with high-risk prostate cancer patients.
-
Elevated expression of a subset of interferon inducible genes in primary bone marrow cells expressing p185 Bcr-Abl versus p210 Bcr-Abl by DNA microarray analysis.
-
Elevated hepatocyte levels of the Forkhead box A2 (HNF-3beta) transcription factor cause postnatal steatosis and mitochondrial damage.
-
Elevated resistin levels induce central leptin resistance and increased atherosclerotic progression in mice.
-
Elevated transferrin receptor impairs T cell metabolism and function in systemic lupus erythematosus.
-
Eliciting and Analyzing Male Mouse Ultrasonic Vocalization (USV) Songs.
-
Eliminating antibody polyreactivity through addition of N-linked glycosylation.
-
Elimination of mycoplasma from human B-lymphoblastoid cell lines.
-
Elucidating a locus coeruleus-dentate gyrus dopamine pathway for operant reinforcement.
-
Elucidating the Candida albicans calcineurin signaling cascade controlling stress response and virulence.
-
Elucidating the molecular mechanism of cardiac remodeling using a comparative genomic approach.
-
Elucidation of The Behavioral Program and Neuronal Network Encoded by Dorsal Raphe Serotonergic Neurons.
-
Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal.
-
Embryonic and neonatal cardiac gene transfer in vivo.
-
Embryonic expression of Lim-1, the mouse homolog of Xenopus Xlim-1, suggests a role in lateral mesoderm differentiation and neurogenesis.
-
Embryonic expression of a haematopoietic growth factor encoded by the Sl locus and the ligand for c-kit.
-
Embryonic expression of mouse bone morphogenetic protein-1 (BMP-1), which is related to the Drosophila dorsoventral gene tolloid and encodes a putative astacin metalloendopeptidase.
-
Embryonic expression patterns of the neural cell adhesion molecule gene are regulated by homeodomain binding sites.
-
Embryonic germ cell lines and their derivation from mouse primordial germ cells.
-
Embryonic germ cells are capable of adipogenic differentiation in vitro and in vivo.
-
Embryonic mouse lung epithelial progenitor cells co-express immunohistochemical markers of diverse mature cell lineages.
-
Emergence and pathogenicity of highly virulent Cryptococcus gattii genotypes in the northwest United States.
-
Emergence of a seizure phenotype in aged apolipoprotein epsilon 4 targeted replacement mice.
-
Emergence of anxiety-like behaviours in depressive-like Cpe(fat/fat) mice.
-
Emerging Skin T-Cell Functions in Response to Environmental Insults.
-
Emerging infectious diseases in an island ecosystem: the New Zealand perspective.
-
Emergomyces africanus in Soil, South Africa.
-
Employing Macrophage-Derived Microvesicle for Kidney-Targeted Delivery of Dexamethasone: An Efficient Therapeutic Strategy against Renal Inflammation and Fibrosis.
-
En bloc substitution of the Src homology region 2 domain activates the transforming potential of the c-Abl protein tyrosine kinase.
-
Enabling hyperpolarized (129) Xe MR spectroscopy and imaging of pulmonary gas transfer to the red blood cells in transgenic mice expressing human hemoglobin.
-
Enabling sublingual peptide immunization with molecular self-assemblies.
-
Encapsulation of Adenovirus BMP2-Transduced Cells with PEGDA Hydrogels Allows Bone Formation in the Presence of Immune Response.
-
Endemic Burkitt lymphoma avatar mouse models for exploring inter-patient tumor variation and testing targeted therapies.
-
EndoU is a novel regulator of AICD during peripheral B cell selection.
-
Endochondral bone formation from hydrogel carriers loaded with BMP2-transduced cells.
-
Endocytosis of Red Blood Cell Microparticles by Pulmonary Endothelial Cells is Mediated By Rab5.
-
Endocytosis of red blood cells or haemoglobin by activated macrophages inhibits their tumoricidal effect.
-
Endogenous CCN family member WISP1 inhibits trauma-induced heterotopic ossification.
-
Endogenous IL-12 is required for induction and expression of experimental autoimmune uveitis.
-
Endogenous Retrovirus Activation as a Key Mechanism of Anti-Tumor Immune Response in Radiotherapy.
-
Endogenous S-nitrosothiols protect against myocardial injury.
-
Endogenous apolipoprotein E suppresses LPS-stimulated microglial nitric oxide production.
-
Endogenous bone morphogenetic protein antagonists regulate mammalian neural crest generation and survival.
-
Endogenous expression of transforming growth factor beta1 inhibits growth and tumorigenicity and enhances Fas-mediated apoptosis in a murine high-grade glioma model.
-
Endogenous glucocorticoids prevent gastric metaplasia by suppressing spontaneous inflammation.
-
Endogenous oncogenic Nras mutation initiates hematopoietic malignancies in a dose- and cell type-dependent manner.
-
Endogenous oncogenic Nras mutation promotes aberrant GM-CSF signaling in granulocytic/monocytic precursors in a murine model of chronic myelomonocytic leukemia.
-
Endogenous polymers of ADP-ribose are associated with the nuclear matrix.
-
Endogenous production of extracellular adenosine by trabecular meshwork cells: potential role in outflow regulation.
-
Endogenous tumor necrosis factor alpha (TNFalpha) requires TNF receptor type 2 to generate heat hyperalgesia in a mouse cancer model.
-
Endoglin deficiency impairs stroke recovery.
-
Endoglin interacts with VEGFR2 to promote angiogenesis.
-
Endoglin promotes transforming growth factor beta-mediated Smad 1/5/8 signaling and inhibits endothelial cell migration through its association with GIPC.
-
Endoglin regulates PI3-kinase/Akt trafficking and signaling to alter endothelial capillary stability during angiogenesis.
-
Endoglin, an ancillary TGFbeta receptor, is required for extraembryonic angiogenesis and plays a key role in heart development.
-
Endometrial epithelial ARID1A is critical for uterine gland function in early pregnancy establishment.
-
Endometrial receptivity and implantation require uterine BMP signaling through an ACVR2A-SMAD1/SMAD5 axis.
-
Endoplasmic reticulum sorting and kinesin-1 command the targeting of axonal GABAB receptors.
-
Endoplasmic reticulum stress, hepatocyte CD1d and NKT cell abnormalities in murine fatty livers.
-
Endostatin inhibits the vascular endothelial growth factor-induced mobilization of endothelial progenitor cells.
-
Endothelial Bmp4 is induced during arterial remodeling: effects on smooth muscle cell migration and proliferation.
-
Endothelial Cell-Derived Extracellular Vesicles Mitigate Radiation-Induced Hematopoietic Injury.
-
Endothelial SUR-8 acts in an ERK-independent pathway during atrioventricular cushion development.
-
Endothelial Stromal PD-L1 (Programmed Death Ligand 1) Modulates CD8+ T-Cell Infiltration After Heart Transplantation.
-
Endothelial TRPV4 channels prevent tumor growth and metastasis via modulation of tumor angiogenesis and vascular integrity.
-
Endothelial and steroidogenic cell migration are regulated by WNT4 in the developing mammalian gonad.
-
Endothelial antigen presentation: stimulation of previously activated but not naïve TCR-transgenic mouse T cells.
-
Endothelial cell Pannexin1 modulates severity of ischemic stroke by regulating cerebral inflammation and myogenic tone.
-
Endothelial cell death, angiogenesis, and microvascular function after castration in an androgen-dependent tumor: role of vascular endothelial growth factor.
-
Endothelial cell surface ATP synthase-triggered caspase-apoptotic pathway is essential for k1-5-induced antiangiogenesis.
-
Endothelial cells adhere to the RGD domain and the fibrinogen-like terminal knob of tenascin.
-
Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome.
-
Endothelial progenitor cell infusion induces hematopoietic stem cell reconstitution in vivo.
-
Endothelial selectins regulate skin wound healing in cooperation with L-selectin and ICAM-1.
-
Endothelial, cardiac muscle and skeletal muscle exhibit different viscous and elastic properties as determined by atomic force microscopy.
-
Endothelin-2 deficiency causes growth retardation, hypothermia, and emphysema in mice.
-
Endothelin-2-mediated protection of mutant photoreceptors in inherited photoreceptor degeneration.
-
Endotoxin (LPS) stimulates in vitro migration of macrophages from LPS-resistant mice but not from LPS-sensitive mice.
-
Endotoxin and NO induce MIP-1gamma gene transcription in ANA-1 murine macrophages.
-
Endotoxin mediated-iNOS induction causes insulin resistance via ONOO⁻ induced tyrosine nitration of IRS-1 in skeletal muscle.
-
Endotoxin stress-response in cardiomyocytes: NF-kappaB activation and tumor necrosis factor-alpha expression.
-
Endotoxin-mediated S-nitrosylation of p50 alters NF-kappa B-dependent gene transcription in ANA-1 murine macrophages.
-
Endotoxin-mediated nitric oxide synthesis inhibits IL-1beta gene transcription in ANA-1 murine macrophages.
-
Endotoxin-mediated synthesis of nitric oxide is dependent on Gq protein signal transduction.
-
Endotoxin-stimulated nitric oxide production inhibits expression of cytochrome c oxidase in ANA-1 murine macrophages.
-
Endovascular middle cerebral artery embolic stroke model: a novel approach.
-
Endurance exercise attenuates juvenile irradiation-induced skeletal muscle functional decline and mitochondrial stress.
-
Endurance exercise training increases adipose tissue glucocorticoid exposure: adaptations that facilitate lipolysis.
-
Energy metabolic reprogramming in the hypertrophied and early stage failing heart: a multisystems approach.
-
Energy metabolism in uncoupling protein 3 gene knockout mice.
-
Enforced expression of FGF-7 promotes epithelial hyperplasia whereas a dominant negative FGFR2iiib promotes the emergence of neuroendocrine phenotype in prostate glands of transgenic mice.
-
Enforcing order within a complex locus: current perspectives on the control of V(D)J recombination at the murine T-cell receptor alpha/delta locus.
-
Engagement of NKG2D on bystander memory CD8 T cells promotes increased immunopathology following Leishmania major infection.
-
Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin.
-
Engineered Fluorescent Strains of Cryptococcus neoformans: a Versatile Toolbox for Studies of Host-Pathogen Interactions and Fungal Biology, Including the Viable but Nonculturable State.
-
Engineered bacterial voltage-gated sodium channel platform for cardiac gene therapy.
-
Engineered leucine zippers show that hemiphosphorylated CREB complexes are transcriptionally active.
-
Engineered pluripotent mesenchymal cells integrate and differentiate in regenerating bone: a novel cell-mediated gene therapy.
-
Engineered skeletal muscle tissue networks with controllable architecture.
-
Engineering Controlled Peritumoral Inflammation to Constrain Brain Tumor Growth.
-
Engineering DNA vaccines via co-delivery of co-stimulatory molecule genes.
-
Engineering Lipid Nanoparticles for Enhanced Intracellular Delivery of mRNA through Inhalation.
-
Engineering a BCR-ABL-activated caspase for the selective elimination of leukemic cells.
-
Engineering and Selection of Shuffled AAV Genomes: A New Strategy for Producing Targeted Biological Nanoparticles.
-
Engineering liver-detargeted AAV9 vectors for cardiac and musculoskeletal gene transfer.
-
Engineering soluble major histocompatibility molecules: why and how.
-
Engraftment of a galactose receptor footprint onto adeno-associated viral capsids improves transduction efficiency.
-
Engraftment of human synovium into severe combined immune deficient mice. Migration of human peripheral blood T cells to engrafted human synovium and to mouse lymph nodes.
-
Enhanced GLUT4-Dependent Glucose Transport Relieves Nutrient Stress in Obese Mice Through Changes in Lipid and Amino Acid Metabolism.
-
Enhanced Galphaq signaling: a common pathway mediates cardiac hypertrophy and apoptotic heart failure.
-
Enhanced In Vivo Delivery of Stem Cells using Microporous Annealed Particle Scaffolds.
-
Enhanced T cell responses due to diacylglycerol kinase zeta deficiency.
-
Enhanced T2 contrast for MR histology of the mouse brain.
-
Enhanced Th17-cell responses render CCR2-deficient mice more susceptible for autoimmune arthritis.
-
Enhanced activation of human dendritic cells by inducible CD40 and Toll-like receptor-4 ligation.
-
Enhanced allergen-induced airway inflammation in paucity of lymph node T cell (plt) mutant mice.
-
Enhanced antibody responses to an HIV-1 membrane-proximal external region antigen in mice reconstituted with cultured lymphocytes.
-
Enhanced avidity maturation of antibody to human immunodeficiency virus envelope: DNA vaccination with gp120-C3d fusion proteins.
-
Enhanced binding and inertness to dehalogenation of alpha-melanotropic peptides labeled using N-succinimidyl 3-iodobenzoate.
-
Enhanced calcium cycling and contractile function in transgenic hearts expressing constitutively active G alpha o* protein.
-
Enhanced capillary amyloid angiopathy-associated pathology in Tg-SwDI mice with deleted nitric oxide synthase 2.
-
Enhanced cardiac function in transgenic mice expressing a Ca(2+)-stimulated adenylyl cyclase.
-
Enhanced central response to dehydration in mice lacking angiotensin AT(1a) receptors.
-
Enhanced chondrogenic differentiation of embryonic stem cells by coculture with hepatic cells.
-
Enhanced chondrogenic differentiation of murine embryonic stem cells in hydrogels with glucosamine.
-
Enhanced contractility and decreased beta-adrenergic receptor kinase-1 in mice lacking endogenous norepinephrine and epinephrine.
-
Enhanced cytoprotective effects of the inhibitor of apoptosis protein cellular IAP1 through stabilization with TRAF2.
-
Enhanced delivery of a monoclonal antibody F(ab')2 fragment to subcutaneous human glioma xenografts using local hyperthermia.
-
Enhanced differentiation of splenic plasma cells but diminished long-lived high-affinity bone marrow plasma cells in aged mice.
-
Enhanced efficacy from gene therapy in Pompe disease using coreceptor blockade.
-
Enhanced efficacy of an AAV vector encoding chimeric, highly secreted acid alpha-glucosidase in glycogen storage disease type II.
-
Enhanced efficacy of combined temozolomide and bromodomain inhibitor therapy for gliomas using targeted nanoparticles.
-
Enhanced efficacy of enzyme replacement therapy in Pompe disease through mannose-6-phosphate receptor expression in skeletal muscle.
-
Enhanced gene expression of systemically administered plasmid DNA in the liver with therapeutic ultrasound and microbubbles.
-
Enhanced green fluorescent protein as a marker for localizing murine cytomegalovirus in acute and latent infection.
-
Enhanced growth of small bowel in transgenic mice expressing human insulin-like growth factor I.
-
Enhanced growth of small bowel in transgenic mice overexpressing bovine growth hormone.
-
Enhanced in vivo cytotoxicity of recombinant human tumor necrosis factor with etoposide in human renal cell carcinoma. Evaluation in a pre-clinical model.
-
Enhanced inflow and outflow rates despite lower IOP in bestrophin-2-deficient mice.
-
Enhanced lithium-induced brain recovery following cranial irradiation is not impeded by inflammation.
-
Enhanced malignant tumorigenesis in Cdk4 transgenic mice.
-
Enhanced melphalan cytotoxicity following buthionine sulfoximine-mediated glutathione depletion in a human medulloblastoma xenograft in athymic mice.
-
Enhanced morphine analgesia in mice lacking beta-arrestin 2.
-
Enhanced myocardial function in transgenic mice overexpressing the beta 2-adrenergic receptor.
-
Enhanced myocardial relaxation in vivo in transgenic mice overexpressing the beta2-adrenergic receptor is associated with reduced phospholamban protein.
-
Enhanced neonatal Fc receptor function improves protection against primate SHIV infection.
-
Enhanced oncolytic activity of vesicular stomatitis virus encoding SV5-F protein against prostate cancer.
-
Enhanced outgrowth of EBV-transformed chronic lymphocytic leukemia B cells mediated by coculture with macrophage feeder cells.
-
Enhanced pancreatic cancer gene therapy by combination of adenoviral vector expressing c-erb-B2 (Her-2/neu)-targeted immunotoxin with a replication-competent adenovirus or etoposide.
-
Enhanced postischemic functional recovery in CYP2J2 transgenic hearts involves mitochondrial ATP-sensitive K+ channels and p42/p44 MAPK pathway.
-
Enhanced priming of adaptive immunity by Mycobacterium smegmatis mutants with high-level protein secretion.
-
Enhanced production of superoxide anion by microglia from trisomy 16 mice.
-
Enhanced refocusing of fat signals using optimized multipulse echo sequences.
-
Enhanced renal leukotriene production in murine lupus: role of lipoxygenase metabolites.
-
Enhanced response to enzyme replacement therapy in Pompe disease after the induction of immune tolerance.
-
Enhanced rewarding properties of morphine, but not cocaine, in beta(arrestin)-2 knock-out mice.
-
Enhanced stability of tristetraprolin mRNA protects mice against immune-mediated inflammatory pathologies.
-
Enhanced therapeutic neovascularization by CD31-expressing cells and embryonic stem cell-derived endothelial cells engineered with chitosan hydrogel containing VEGF-releasing microtubes
-
Enhanced tonic GABA current in normotopic and hilar ectopic dentate granule cells after pilocarpine-induced status epilepticus.
-
Enhanced transduction and improved photoreceptor survival of retinal degeneration by the combinatorial use of rAAV2 with a lower dose of adenovirus.
-
Enhanced tumor localization and in vivo stability of a monoclonal antibody radioiodinated using N-succinimidyl 3-(tri-n-butylstannyl)benzoate.
-
Enhanced tumour uptake and in vitro radiotoxicity of no-carrier-added [131I]meta-iodobenzylguanidine: implications for the targeted radiotherapy of neuroblastoma.
-
Enhanced tumour uptake of radiolabelled antibodies by hyperthermia. Part II: Application of the thermal equivalency equation.
-
Enhanced tumour uptake of radiolabelled antibodies by hyperthermia: Part I: Timing of injection relative to hyperthermia.
-
Enhanced type 1 immunity after secondary viral challenge in mice primed as neonates.
-
Enhancement of Outflow Facility in the Murine Eye by Targeting Selected Tight-Junctions of Schlemm's Canal Endothelia.
-
Enhancement of anti-tumor immunity through local modulation of CTLA-4 and GITR by dendritic cells.
-
Enhancement of antibodies to the human immunodeficiency virus type 1 envelope by using the molecular adjuvant C3d.
-
Enhancement of cancer radiation therapy by use of adenovirus-mediated secretable glucose-regulated protein 94/gp96 expression.
-
Enhancement of electric field-mediated gene delivery through pretreatment of tumors with a hyperosmotic mannitol solution.
-
Enhancement of endocrine pancreatic secretions by essential fatty acids.
-
Enhancement of experimental anaerobic infections by blood, hemoglobin, and hemostatic agents.
-
Enhancement of irinotecan (CPT-11) activity against central nervous system tumor xenografts by alkylating agents.
-
Enhancement of macrophage-mediated tumor cell killing by bacterial outer membrane proteins (porins).
-
Enhancement of melphalan activity by inhibition of DNA polymerase-alpha and DNA polymerase-beta.
-
Enhancement of melphalan-induced gastrointestinal toxicity in mice treated with regional hyperthermia and BSO-mediated glutathione depletion.
-
Enhancement of nitrosourea activity in medulloblastoma and glioblastoma multiforme.
-
Enhancement of rAAV2-mediated transgene expression in retina cells in vitro and in vivo by coadministration of low-dose chemotherapeutic drugs.
-
Enhancement of radiotherapy by hyperthermia-regulated gene therapy.
-
Enhancer Histone Acetylation Modulates Transcriptional Bursting Dynamics of Neuronal Activity-Inducible Genes.
-
Enhancer analysis of the mouse HNF-3 beta gene: regulatory elements for node/notochord and floor plate are independent and consist of multiple sub-elements.
-
Enhancer control of local accessibility to V(D)J recombinase.
-
Enhancer-blocking activity within the DNase I hypersensitive site 2 to 6 region between the TCR alpha and Dad1 genes.
-
Enhancing Radiation Therapy Through Cherenkov Light-Activated Phototherapy.
-
Enhancing human islet transplantation by localized release of trophic factors from PLG scaffolds.
-
Enhancing the immunostimulatory function of dendritic cells by transfection with mRNA encoding OX40 ligand.
-
Enrichment of endogenous fractalkine and anti-inflammatory cells via aptamer-functionalized hydrogels.
-
Enrichment of putative prostate cancer stem cells after androgen deprivation: upregulation of pluripotency transactivators concurs with resistance to androgen deprivation in LNCaP cell lines.
-
Enterocyte-innate lymphoid cell crosstalk drives early IFN-γ-mediated control of Cryptosporidium.
-
Enterotoxigenic Escherichia coli vesicles target toxin delivery into mammalian cells.
-
Enterovirus Replication and Dissemination Are Differentially Controlled by Type I and III Interferons in the Gastrointestinal Tract.
-
Environmental Factors Modify the Severity of Acute DSS Colitis in Caspase-11-Deficient Mice.
-
Environmental oxygen regulates astrocyte proliferation to guide angiogenesis during retinal development.
-
Environmental toxin-linked nonalcoholic steatohepatitis and hepatic metabolic reprogramming in obese mice.
-
Environmentally relevant xenoestrogen tissue concentrations correlated to biological responses in mice.
-
Enzymes that counteract nitrosative stress promote fungal virulence.
-
Eosinophil-derived leukotriene C4 signals via type 2 cysteinyl leukotriene receptor to promote skin fibrosis in a mouse model of atopic dermatitis.
-
Eosinophils Mediate Tissue Injury in the Autoimmune Skin Disease Bullous Pemphigoid.
-
EphB2 receptor controls proliferation/migration dichotomy of glioblastoma by interacting with focal adhesion kinase.
-
Epicutaneous sensitization results in IgE-dependent intestinal mast cell expansion and food-induced anaphylaxis.
-
Epidermal Growth Factor and Granulocyte Colony Stimulating Factor Signaling Are Synergistic for Hematopoietic Regeneration.
-
Epidermal growth factor alters metabolism of inositol lipids and activity of protein kinase C in mouse embryo palate mesenchyme cells.
-
Epidermal growth factor augments adaptation following small bowel resection: optimal dosage, route, and timing of administration.
-
Epidermal growth factor ligand-independent, unregulated, cell-transforming potential of a naturally occurring human mutant EGFRvIII gene.
-
Epidermal growth factor receptor VIII peptide vaccination is efficacious against established intracerebral tumors.
-
Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanisms.
-
Epidermal growth factor receptor cooperates with signal transducer and activator of transcription 3 to induce epithelial-mesenchymal transition in cancer cells via up-regulation of TWIST gene expression.
-
Epidermal growth factor receptor trans-activation mediates the tonic and fibrogenic effects of endothelin in the aortic wall of transgenic mice.
-
Epidermal growth factor regulates hematopoietic regeneration after radiation injury.
-
Epidermal growth factor replaces estrogen in the stimulation of female genital-tract growth and differentiation.
-
Epigallocatechin-3-gallate (EGCG), a green tea polyphenol, stimulates hepatic autophagy and lipid clearance.
-
Epigenetic Heterogeneity in Human Colorectal Tumors Reveals Preferential Conservation And Evidence of Immune Surveillance.
-
Epigenetic Regulation of Fanconi Anemia Genes Implicates PRMT5 Blockage as a Strategy for Tumor Chemosensitization.
-
Epigenetic Regulation of GDF2 Suppresses Anoikis in Ovarian and Breast Epithelia.
-
Epigenetic Switch-Induced Viral Mimicry Evasion in Chemotherapy-Resistant Breast Cancer.
-
Epigenetic dysregulation of Oxtr in Tet1-deficient mice has implications for neuropsychiatric disorders.
-
Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage.
-
Epigenetic propagation of CD4 expression is established by the Cd4 proximal enhancer in helper T cells.
-
Epigenetic regulation of CD133 and tumorigenicity of CD133+ ovarian cancer cells.
-
Epigenetic silencing of tumor suppressor Par-4 promotes chemoresistance in recurrent breast cancer.
-
Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition.
-
Epigenetics and the regulation of stress vulnerability and resilience.
-
Epigenomic comparison reveals activation of "seed" enhancers during transition from naive to primed pluripotency.
-
Epigenomic diversity of cortical projection neurons in the mouse brain.
-
Epilepsy genetics: an abundance of riches for biologists.
-
Epinephrine-induced activation of LW-mediated sickle cell adhesion and vaso-occlusion in vivo.
-
Epiregulin and EGFR interactions are involved in pain processing.
-
Epithalon decelerates aging and suppresses development of breast adenocarcinomas in transgenic her-2/neu mice.
-
Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis.
-
Epithelial Smad4 Deletion Up-Regulates Inflammation and Promotes Inflammation-Associated Cancer.
-
Epithelial progenitor cells of the embryonic lung and the role of microRNAs in their proliferation.
-
Epithelial progesterone receptor exhibits pleiotropic roles in uterine development and function.
-
Epithelial splicing regulatory protein 2-mediated alternative splicing reprograms hepatocytes in severe alcoholic hepatitis.
-
Epithelial stem/progenitor cells in lung postnatal growth, maintenance, and repair.
-
Epithelial-mesenchymal transition in prostate cancer: providing new targets for therapy.
-
Epithelial-mesenchymal transitions and hepatocarcinogenesis.
-
Epitope insertion into variable loops of HIV-1 gp120 as a potential means to improve immunogenicity of viral envelope protein.
-
Epitope maps of the Escherichia coli heat-labile toxin B subunit for development of a synthetic oral vaccine.
-
Eps15 is constitutively oligomerized due to homophilic interaction of its coiled-coil region.
-
Epstein Barr virus nuclear antigen 1 (EBNA-1) peptides recognized by adult multiple sclerosis patient sera induce neurologic symptoms in a murine model.
-
Epstein-Barr virus ensures B cell survival by uniquely modulating apoptosis at early and late times after infection.
-
Epstein-Barr virus latent infection membrane protein 1 TRAF-binding site induces NIK/IKK alpha-dependent noncanonical NF-kappaB activation.
-
Eradication of melanoma pulmonary metastases by immunotherapy with tumor cells engineered to secrete interleukin-2 or gamma interferon.
-
Eradication of solid human breast tumors in nude mice with an intravenously injected light-emitting oncolytic vaccinia virus.
-
Erk2 phosphorylation of Drp1 promotes mitochondrial fission and MAPK-driven tumor growth.
-
Erlotinib-mediated inhibition of EGFR signaling induces metabolic oxidative stress through NOX4.
-
Erythrocyte plasma membrane-bound ERK1/2 activation promotes ICAM-4-mediated sickle red cell adhesion to endothelium.
-
Erythrocyte-Derived Microparticles Activate Pulmonary Endothelial Cells in a Murine Model of Transfusion.
-
Erythroid AP-1/NF-E2 elements vary in their response to NF-E2.
-
Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein.
-
Erythroid-specific expression of human CD59 and transfer to vascular endothelial cells.
-
Erythromyeloid progenitors give rise to a population of osteoclasts that contribute to bone homeostasis and repair.
-
Erythropoietin Synthesis in Renal Myofibroblasts Is Restored by Activation of Hypoxia Signaling.
-
Erythropoietin activates mitochondrial biogenesis and couples red cell mass to mitochondrial mass in the heart.
-
Erythropoietin blockade inhibits the induction of tumor angiogenesis and progression.
-
Erythropoietin hypersensitivity in primary familial and congenital polycythemia: role of tyrosines Y285 and Y344 in erythropoietin receptor cytoplasmic domain.
-
Erythropoietin mediates terminal granulocytic differentiation of committed myeloid cells with ectopic erythropoietin receptor expression.
-
Erythropoietin receptor contains both growth-promoting activity and differentiation-promoting activity.
-
Erythropoietin receptor contributes to melanoma cell survival in vivo.
-
Erythropoietin receptor signals both proliferation and erythroid-specific differentiation.
-
Escape from tolerance in the human X-linked autoimmunity-allergic disregulation syndrome and the Scurfy mouse.
-
Escherichia coli global gene expression in urine from women with urinary tract infection.
-
Essential Role of mTORC1 in Self-Renewal of Murine Alveolar Macrophages.
-
Essential and unexpected role of Yin Yang 1 to promote mesodermal cardiac differentiation.
-
Essential cell-extrinsic requirement for PDIA6 in lymphoid and myeloid development.
-
Essential role for NHERF in cAMP-mediated inhibition of the Na+-HCO3- co-transporter in BSC-1 cells.
-
Essential role for Smad3 in regulating MCP-1 expression and vascular inflammation.
-
Essential role of AT1A receptor in the development of 2K1C hypertension.
-
Essential role of ICAM-1/CD18 in mediating EPC recruitment, angiogenesis, and repair to the infarcted myocardium.
-
Essential role of LAT in T cell development.
-
Essential role of PR-domain protein MDS1-EVI1 in MLL-AF9 leukemia.
-
Essential role of Smad3 in infarct healing and in the pathogenesis of cardiac remodeling.
-
Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function.
-
Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock.
-
Establishing an accurate gas phase reference frequency to quantify 129 Xe chemical shifts in vivo.
-
Establishing the epigenetic status of the Prader-Willi/Angelman imprinting center in the gametes and embryo.
-
Establishment and characterization of a new human prostatic carcinoma cell line (DuPro-1).
-
Establishment and characterization of conditionally immortalized cells from the mouse urogenital ridge.
-
Establishment and characterization of the human medulloblastoma cell line and transplantable xenograft D283 Med.
-
Establishment of a melphalan-resistant rhabdomyosarcoma xenograft with cross-resistance to vincristine and enhanced sensitivity following buthionine sulfoximine-mediated glutathione depletion.
-
Establishment of an index with increased sensitivity for assessing murine arthritis.
-
Establishment of experimental eosinophilic vasculitis by IgE-mediated cutaneous reverse passive arthus reaction.
-
Establishment of multi-stage intravenous self-administration paradigms in mice.
-
Esterified Trehalose Analogues Protect Mammalian Cells from Heat Shock.
-
Estimation of primate speciation dates using local molecular clocks.
-
Estradiol enhances long term potentiation in hippocampal slices from aged apoE4-TR mice.
-
Estradiol replacement enhances cocaine-stimulated locomotion in female C57BL/6 mice through estrogen receptor alpha.
-
Estradiol replacement therapy regulates innate immune response in ovariectomized arthritic mice.
-
Estrogen mediates inflammatory role of mast cells in endometriosis pathophysiology.
-
Estrogen mediates neuroprotection and anti-inflammatory effects during EAE through ERα signaling on astrocytes but not through ERβ signaling on astrocytes or neurons.
-
Estrogen metabolism within the lung and its modulation by tobacco smoke.
-
Estrogen protects against intracranial aneurysm rupture in ovariectomized mice.
-
Estrogen receptor beta protects against in vivo injury in RPE cells.
-
Estrogen receptor gene disruption: molecular characterization and experimental and clinical phenotypes.
-
Estrogen receptor-beta mediates male-female differences in the development of pressure overload hypertrophy.
-
Estrogen receptor-β ligand treatment after disease onset is neuroprotective in the multiple sclerosis model.
-
Estrogen regulation of aquaporins in the mouse uterus: potential roles in uterine water movement.
-
Estrogen stimulation and tamoxifen inhibition of leiomyoma cell growth in vitro and in vivo.
-
Estrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiation.
-
Estrogen/antiestrogen responsiveness in an in vivo/in vitro model for myometrial tumorigenesis.
-
Estrogenic activity of a dieldrin/toxaphene mixture in the mouse uterus, MCF-7 human breast cancer cells, and yeast-based estrogen receptor assays: no apparent synergism.
-
Ethanol augments GABAergic transmission in the central amygdala via CRF1 receptors.
-
Ethanol contributes to neurogenic pancreatitis by activation of TRPV1.
-
Ethanol induces redox-sensitive cell-cycle inhibitors and inhibits liver regeneration after partial hepatectomy.
-
Ethanol metabolism modifies hepatic protein acylation in mice.
-
Ethanol-induced face-brain dysmorphology patterns are correlative and exposure-stage dependent.
-
Ether lipid metabolism by AADACL1 regulates platelet function and thrombosis.
-
Ethosuximide reduces ethanol withdrawal-mediated disruptions in sleep-related EEG patterns.
-
Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation.
-
Ethylenecarbodiimide-fixed donor splenocyte infusions differentially target direct and indirect pathways of allorecognition for induction of transplant tolerance.
-
Ethylenecarbodiimide-treated splenocytes carrying male CD4 epitopes confer histocompatibility Y chromosome antigen transplant protection by inhibiting CD154 upregulation.
-
Etomoxir-induced PPARalpha-modulated enzymes protect during acute renal failure.
-
Ets-1 and runx2 regulate transcription of a metastatic gene, osteopontin, in murine colorectal cancer cells.
-
Eukaryotic transcription termination factor La mediates transcript release and facilitates reinitiation by RNA polymerase III.
-
EuroPhenome: a repository for high-throughput mouse phenotyping data.
-
Evaluating Skilled Prehension in Mice Using an Auto-Trainer.
-
Evaluating cytokine production by flow cytometry using brefeldin A in mice.
-
Evaluation of 5-(2-(4-pyridinyl)vinyl)-6-chloro-3-(1-methyl-2-(S)-pyrrolidinylmethoxy)pyridine and its analogues as PET radioligands for imaging nicotinic acetylcholine receptors.
-
Evaluation of Alternative In Vivo Drug Screening Methodology: A Single Mouse Analysis.
-
Evaluation of Lipin 2 as a candidate gene for autosomal dominant 1 high-grade myopia.
-
Evaluation of M2-like macrophage enrichment after diffuse traumatic brain injury through transient interleukin-4 expression from engineered mesenchymal stromal cells.
-
Evaluation of Maternal, Embryo, and Placental Effects in CD-1 Mice following Gestational Exposure to Perfluorooctanoic Acid (PFOA) or Hexafluoropropylene Oxide Dimer Acid (HFPO-DA or GenX).
-
Evaluation of a digital microfluidic real-time PCR platform to detect DNA of Candida albicans in blood.
-
Evaluation of a recombinant yeast cell estrogen screening assay.
-
Evaluation of an anti-p185(HER2) (scFv-C(H)2-C(H)3)2 fragment following radioiodination using two different residualizing labels: SGMIB and IB-Mal-D-GEEEK.
-
Evaluation of an improved fiberoptics luminescence skin monitor with background correction.
-
Evaluation of an internalizing monoclonal antibody labeled using N-succinimidyl 3-[131I]iodo-4-phosphonomethylbenzoate ([131I]SIPMB), a negatively charged substituent bearing acylation agent.
-
Evaluation of anti-podoplanin rat monoclonal antibody NZ-1 for targeting malignant gliomas.
-
Evaluation of antihypertensive drugs in combination with enzyme replacement therapy in mice with Pompe disease.
-
Evaluation of host immune responses to pulmonary cryptococcosis using a temperature-sensitive C. neoformans calcineurin A mutant strain.
-
Evaluation of humoral, mucosal, and cellular immune responses following co-immunization of HIV-1 Gag and Env proteins expressed by Newcastle disease virus.
-
Evaluation of meta-[211At]astatobenzylguanidine in an athymic mouse human neuroblastoma xenograft model.
-
Evaluation of new anticancer agents against human pancreatic carcinomas in nude mice.
-
Evaluation of p-amidinophenyl esters as potential antithrombotic agents.
-
Evaluation of penicillin and hyperbaric oxygen in the treatment of streptococcal myositis.
-
Evaluation of recombinant adenovirus vaccines based on glycoprotein D and truncated UL25 against herpes simplex virus type 2 in mice.
-
Evaluation of the alpha(2A)-adrenergic receptor gene in a heritable form of temporal lobe epilepsy.
-
Evaluation of the effect of transcytolemmal water exchange analysis for therapeutic response assessment using DCE-MRI: a comparison study.
-
Evaluation of the pharmacological activities of RAD1901, a selective estrogen receptor degrader.
-
Evaluation of the rapid plasma elimination of recombinant alpha 1-proteinase inhibitor: synthesis of polyethylene glycol conjugates with improved therapeutic potential.
-
Evaluation of tumor microenvironment in an animal model using a nanoparticle contrast agent in computed tomography imaging.
-
Evans blue dye-enhanced capillary-resolution photoacoustic microscopy in vivo.
-
Evasion of immune responses to introduced human acid alpha-glucosidase by liver-restricted expression in glycogen storage disease type II.
-
Evidence for Feedback Regulation Following Cholesterol Lowering Therapy in a Prostate Cancer Xenograft Model.
-
Evidence for a role of Met-HGF/SF during Ras-mediated tumorigenesis/metastasis.
-
Evidence for a second alpha 2-macroglobulin receptor.
-
Evidence for an alternative glycolytic pathway in rapidly proliferating cells.
-
Evidence for an immune barrier after in utero hematopoietic-cell transplantation.
-
Evidence for disruption of sphingolipid metabolism as a contributing factor in the toxicity and carcinogenicity of fumonisins.
-
Evidence for epithelial-mesenchymal transitions in adult liver cells.
-
Evidence for phenotypic plasticity in aggressive triple-negative breast cancer: human biology is recapitulated by a novel model system.
-
Evidence for positive and negative regulatory elements in the 5'-flanking sequence of the mouse sparc (osteonectin) gene.
-
Evidence for the Role of a Second Fc-Binding Receptor in Placental IgG Transfer in Nonhuman Primates.
-
Evidence for the existence of renin in the heart.
-
Evidence for the involvement of the Gli gene family in embryonic mouse lung development.
-
Evidence for two cellular pathways of renin secretion by the mouse submandibular gland.
-
Evidence for type II cells as cells of origin of K-Ras-induced distal lung adenocarcinoma.
-
Evidence from molecular cloning that SPARC, a major product of mouse embryo parietal endoderm, is related to an endothelial cell 'culture shock' glycoprotein of Mr 43,000.
-
Evidence from normal expression and targeted misexpression that bone morphogenetic protein (Bmp-4) plays a role in mouse embryonic lung morphogenesis.
-
Evidence of severe mitochondrial oxidative stress and a protective effect of low oxygen in mouse models of inherited photoreceptor degeneration.
-
Evidence that Gsta4 modifies susceptibility to skin tumor development in mice and humans.
-
Evidence that Hensen's node is a site of retinoic acid synthesis.
-
Evidence that Mothers-against-dpp-related 1 (Madr1) plays a role in the initiation and maintenance of spermatogenesis in the mouse.
-
Evidence that SOX2 overexpression is oncogenic in the lung.
-
Evidence that autocrine signaling through Bmpr1a regulates the proliferation, survival and morphogenetic behavior of distal lung epithelial cells.
-
Evidence that mouse Bmp8a (Op2) and Bmp8b are duplicated genes that play a role in spermatogenesis and placental development.
-
Evidence that polyphenols do not inhibit the phospholipid scramblase TMEM16F.
-
Evidence that the platinum-reactive methionyl residue of the alpha 2-macroglobulin receptor recognition site is not in the carboxyl-terminal receptor binding domain.
-
Evidence that there is no direct correlation between alpha 2-adrenoceptor antagonism and inhibition of voltage-dependent sodium channels.
-
Evidence-ranked motif identification.
-
Evolution and development of the mammalian dentition: insights from the marsupial Monodelphis domestica.
-
Evolution of the tenascin family--implications for function of the C-terminal fibrinogen-like domain.
-
Evolutionarily conserved role of calcineurin in phosphodegron-dependent degradation of phosphodiesterase 4D.
-
Evolutionary and ecological functional genomics.
-
Ex Vivo MR Histology and Cytometric Feature Mapping Connect Three-dimensional in Vivo MR Images to Two-dimensional Histopathologic Images of Murine Sarcomas.
-
Ex vivo expansion of murine and human hematopoietic stem cells.
-
Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone.
-
Ex vivo pediatric brain tumors express Fas (CD95) and FasL (CD95L) and are resistant to apoptosis induction.
-
Ex vivo spermine dialdehyde treatment prevents lethal GVHD in a murine bone marrow transplantation model.
-
Exacerbation of established pulmonary fibrosis in a murine model by gammaherpesvirus.
-
Exaggerated peripheral responses to catecholamines contributes to stress-induced hyperglycemia in the ob/ob mouse.
-
Exceptional aggressiveness of cerebral cavernous malformation disease associated with PDCD10 mutations.
-
Exceptionally potent antispermatogenic compounds from 8-halogenation of (4aRS,5SR,9bRS)-hexahydroindeno-[1,2-c]pyridines.
-
Exercise Increases Bone in SEIPIN Deficient Lipodystrophy, Despite Low Marrow Adiposity.
-
Exercise activates vagal induction of dopamine and attenuates systemic inflammation.
-
Exercise can prevent and reverse the severity of hypertrophic cardiomyopathy.
-
Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway.
-
Exercise modulation of the host-tumor interaction in an orthotopic model of murine prostate cancer.
-
Exercise protects against cardiac and skeletal muscle dysfunction in a mouse model of inflammatory arthritis.
-
Exercise stimulates Pgc-1alpha transcription in skeletal muscle through activation of the p38 MAPK pathway.
-
Exhausted CD8 T cells downregulate the IL-18 receptor and become unresponsive to inflammatory cytokines and bacterial co-infections.
-
Exogenous PP2A inhibitor exacerbates the progression of nonalcoholic fatty liver disease via NOX2-dependent activation of miR21.
-
Exogenous leptin enhances markers of airway fibrosis in a mouse model of chronic allergic airways disease.
-
Exogenous pyruvate prevents stress-evoked suppression of mitogen-stimulated proliferation.
-
Exosomal CCL2 from Tubular Epithelial Cells Is Critical for Albumin-Induced Tubulointerstitial Inflammation.
-
Exosomes Produced by Mesenchymal Stem Cells Drive Differentiation of Myeloid Cells into Immunosuppressive M2-Polarized Macrophages in Breast Cancer.
-
Exosomes decorated with a recombinant SARS-CoV-2 receptor-binding domain as an inhalable COVID-19 vaccine.
-
Expanded Satellite Repeats Amplify a Discrete CENP-A Nucleosome Assembly Site on Chromosomes that Drive in Female Meiosis.
-
Expanded breadth of the T-cell response to mosaic human immunodeficiency virus type 1 envelope DNA vaccination.
-
Expanded polyglutamine domain proteins bind neurofilament and alter the neurofilament network.
-
Expanding anti-CD38 immunotherapy for lymphoid malignancies.
-
Expanding gliogenesis.
-
Expansion of adult beta-cell mass in response to increased metabolic demand is dependent on HNF-4alpha.
-
Expansion of the Parkinson disease-associated SNCA-Rep1 allele upregulates human alpha-synuclein in transgenic mouse brain.
-
Expansion of the human mu-opioid receptor gene architecture: novel functional variants.
-
Expansion or elimination of B cells in vivo: dual roles for CD40- and Fas (CD95)-ligands modulated by the B cell antigen receptor.
-
Experience and activity-dependent maturation of perisomatic GABAergic innervation in primary visual cortex during a postnatal critical period.
-
Experience-dependent modification of a central amygdala fear circuit.
-
Experimental Models of Short Courses of Liposomal Amphotericin B for Induction Therapy for Cryptococcal Meningitis.
-
Experimental and pan-cancer genome analyses reveal widespread contribution of acrylamide exposure to carcinogenesis in humans.
-
Experimental autoimmune encephalomyelitis in mice lacking glial fibrillary acidic protein is characterized by a more severe clinical course and an infiltrative central nervous system lesion.
-
Experimental chemotherapy of human medulloblastoma cell lines and transplantable xenografts with bifunctional alkylating agents.
-
Experimental chemotherapy of human medulloblastoma with classical alkylators.
-
Experimental effects of hyperbaric oxygen on selected clostridial species. II. In-vitro studies in mice.
-
Experimental evaluation of rodent exclusion methods to reduce hantavirus transmission to residents in a Native American community in New Mexico.
-
Experimental models of human carcinogenesis.
-
Experimental ocular toxocariasis: a mouse model.
-
Experimental study of the effect of diethylstilbestrol on the development of the human female reproductive tract.
-
Experimental validation of an inverse fluorescence Monte Carlo model to extract concentrations of metabolically relevant fluorophores from turbid phantoms and a murine tumor model.
-
Exploitation of macrophages as a replication niche by Legionella pneumophila: response.
-
Exploiting Pre-Existing CD4+ T Cell Help from Bacille Calmette-Guérin Vaccination to Improve Antiviral Antibody Responses.
-
Exploiting innate immune cell activation of a copper-dependent antimicrobial agent during infection.
-
Exploring the role of the beta-adrenergic receptor kinase in cardiac disease using gene-targeted mice.
-
Exploring type I angiotensin (AT1) receptor functions through gene targeting.
-
Exploring variation in binding of Protein A and Protein G to immunoglobulin type G by isothermal titration calorimetry.
-
Exposure of cultured murine peritoneal macrophages to low concentrations of beryllium induces increases in intracellular calcium concentrations and stimulates DNA synthesis.
-
Exposure of mice to topical bovine thrombin induces systemic autoimmunity.
-
Exposure to a youthful circulaton rejuvenates bone repair through modulation of β-catenin.
-
Exposure to hyperbaric oxygen not beneficial for murine tetanus.
-
Exposure to particulate hexavalent chromium exacerbates allergic asthma pathology.
-
Expression analysis of the T-cell-targeting chemokines CXCL9 and CXCL10 in mice and humans with endothelial infections caused by rickettsiae of the spotted fever group.
-
Expression and Role of Voltage-Gated Sodium Channels in Human Dorsal Root Ganglion Neurons with Special Focus on Nav1.7, Species Differences, and Regulation by Paclitaxel.
-
Expression and function of the gamma c subunit of the IL-2, IL-4, and IL-7 receptors. Distinct interaction of gamma c in the IL-4 receptor.
-
Expression and functional analysis of Gm114, a putative mammalian ortholog of Drosophila bam.
-
Expression and localization of components of the histone deacetylases multiprotein repressory complexes in the mouse preimplantation embryo.
-
Expression and modification of Hox 2.1 protein in mouse embryos.
-
Expression and modulation of RPE cell membrane complement regulatory proteins.
-
Expression and regulation of calcium-independent protein kinase C in NG 108-15 cell differentiation.
-
Expression and subcellular distribution of mouse cytochrome P1-450 mRNA as determined by molecular hybridization with cloned P1-450 DNA.
-
Expression and trafficking of placental microRNAs at the feto-maternal interface.
-
Expression cloning of type 2 angiotension II receptor reveals a unique class of seven-transmembrane receptors.
-
Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis.
-
Expression of C3b receptors on human be cells and myelomonocytic cells but not natural killer cells.
-
Expression of C3d receptors during human B cell differentiation: immunofluorescence analysis with the HB-5 monoclonal antibody.
-
Expression of CDK4 or CDK2 in mouse oral cavity is retained in adult pituitary with distinct effects on tumorigenesis.
-
Expression of CXC chemokine receptor-4 enhances the pulmonary metastatic potential of murine B16 melanoma cells.
-
Expression of Ca(2+)/calmodulin-dependent protein kinase IV (caMKIV) messenger RNA during murine embryogenesis.
-
Expression of EGF receptor and transferrin by F9 and PC13 teratocarcinoma cells.
-
Expression of FMS-like tyrosine kinase 3 ligand by oncolytic herpes simplex virus type I prolongs survival in mice bearing established syngeneic intracranial malignant glioma.
-
Expression of Mls determinants in mice exhibiting the severe combined immunodeficiency (scid) mutation or X-linked immunodeficiency (xid) defect.
-
Expression of Neurogenin 1 in mouse embryonic stem cells directs the differentiation of neuronal precursors and identifies unique patterns of down-stream gene expression.
-
Expression of Sry, the mouse sex determining gene.
-
Expression of TIMP in fetal and adult mouse tissues studied by in situ hybridization.
-
Expression of a beta-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice.
-
Expression of a candidate sex-determining gene during mouse testis differentiation.
-
Expression of a constitutive form of calcium/calmodulin dependent protein kinase II leads to arrest of the cell cycle in G2.
-
Expression of a highly conserved anti-DNA idiotype in normal and autoimmune mice.
-
Expression of a murine cytomegalovirus early-late protein in "latently" infected mice.
-
Expression of a peptide inhibitor of protein phosphatase 1 increases phosphorylation and activity of CREB in NIH 3T3 fibroblasts.
-
Expression of an antisense transforming growth factor-beta1 transgene reduces tumorigenicity of EMT6 mammary tumor cells.
-
Expression of c-fos in parietal endoderm, amnion and differentiating F9 teratocarcinoma cells.
-
Expression of cadherin-11 delineates boundaries, neuromeres, and nuclei in the developing mouse brain.
-
Expression of chimeric tRNA-driven antisense transcripts renders NIH 3T3 cells highly resistant to Moloney murine leukemia virus replication.
-
Expression of constitutively active Raf-1 in the mitochondria restores antiapoptotic and leukemogenic potential of a transformation-deficient BCR/ABL mutant.
-
Expression of cytokine mRNA in murine splenic dendritic cells and better induction of T cell-derived cytokines by dendritic cells than by macrophages during in vitro costimulation assay using specific antigens.
-
Expression of ectopic heat shock protein 90 in male and female primary afferent nociceptors regulates inflammatory pain.
-
Expression of extracellular glutathione peroxidase in human and mouse gastrointestinal tract.
-
Expression of full-length and truncated dystrophin mini-genes in transgenic mdx mice.
-
Expression of functional estrogen receptor beta in locus coeruleus-derived Cath.a cells.
-
Expression of glucokinase in cultured human muscle cells confers insulin-independent and glucose concentration-dependent increases in glucose disposal and storage.
-
Expression of heme oxygenase-1 can determine cardiac xenograft survival.
-
Expression of heterogeneous nuclear ribonucleoprotein A2/B1 changes with critical stages of mammalian lung development.
-
Expression of high mobility group protein 1 in the sera of patients and mice with systemic lupus erythematosus.
-
Expression of homeo box genes during mouse development: a review.
-
Expression of human complement factor H prevents age-related macular degeneration-like retina damage and kidney abnormalities in aged Cfh knockout mice.
-
Expression of membrane Hsp90 is a molecular signature of T cell activation.
-
Expression of mitochondrial membrane-linked SAB determines severity of sex-dependent acute liver injury.
-
Expression of murine leukemia virus structural antigens on the surface of chemically induced murine sarcomas.
-
Expression of normal and novel glucokinase mRNAs in anterior pituitary and islet cells.
-
Expression of olfactory signaling genes in the eye.
-
Expression of recombinant human methylmalonyl-CoA mutase: in primary mut fibroblasts and Saccharomyces cerevisiae.
-
Expression of stimulator of Fe transport is not enhanced in Hfe knockout mice.
-
Expression of the 71 kDa dystrophin isoform (Dp71) evaluated by gene targeting.
-
Expression of the AT2 receptor developmentally programs extracellular signal-regulated kinase activity and influences fetal vascular growth.
-
Expression of the DMT1 (NRAMP2/DCT1) iron transporter in mice with genetic iron overload disorders.
-
Expression of the apolipoprotein E gene does not affect motor recovery after sensorimotor cortex injury in the mouse.
-
Expression of the homeobox genes Hox 2.1 and 2.6 during mouse development.
-
Expression of the human poliovirus receptor/CD155 gene during development of the central nervous system: implications for the pathogenesis of poliomyelitis.
-
Expression of the human poliovirus receptor/CD155 gene is activated by sonic hedgehog.
-
Expression of the protein tyrosine phosphatase, phosphatase of regenerating liver 1, in the outer segments of primate cone photoreceptors.
-
Expression of tissue factor in tumor stroma correlates with progression to invasive human breast cancer: paracrine regulation by carcinoma cell-derived members of the transforming growth factor beta family.
-
Expression of transforming growth factor beta 2 RNA during murine embryogenesis.
-
Expression of transforming growth factor beta type II receptor leads to reduced malignancy in human breast cancer MCF-7 cells.
-
Expression of tumor necrosis factor receptor-1 in arterial wall cells promotes atherosclerosis.
-
Expression of utrophin A mRNA correlates with the oxidative capacity of skeletal muscle fiber types and is regulated by calcineurin/NFAT signaling.
-
Expression of v-Ha-ras driven by the calcitonin/calcitonin gene-related peptide promoter: a novel transgenic murine model for medullary thyroid carcinoma.
-
Expression profiling of a transformed thymocyte cell line undergoing maturation in vitro identifies multiple genes involved in positive selection.
-
Expression profiling of in vivo ductal carcinoma in situ progression models identified B cell lymphoma-9 as a molecular driver of breast cancer invasion.
-
Expression, enzyme activity, and subcellular localization of mammalian target of rapamycin in insulin-responsive cells.
-
Extending principles learned in model systems to clinical trials design.
-
Extension of O-Linked Mannosylation in the Golgi Apparatus Is Critical for Cell Wall Integrity Signaling and Interaction with Host Cells in Cryptococcus neoformans Pathogenesis.
-
Extracellular caspase-6 drives murine inflammatory pain via microglial TNF-α secretion.
-
Extracellular matrix protein betaig-h3/TGFBI promotes metastasis of colon cancer by enhancing cell extravasation.
-
Extracellular microRNAs activate nociceptor neurons to elicit pain via TLR7 and TRPA1.
-
Extracellular phospholipase activity is a virulence factor for Cryptococcus neoformans.
-
Extracellular signal-regulated kinase regulation of tumor necrosis factor-alpha mRNA nucleocytoplasmic transport requires TAP-NxT1 binding and the AU-rich element.
-
Extracellular superoxide dismutase deficiency worsens outcome from focal cerebral ischemia in the mouse.
-
Extracellular superoxide dismutase in the airways of transgenic mice reduces inflammation and attenuates lung toxicity following hyperoxia.
-
Extracellular superoxide dismutase overexpression improves behavioral outcome from closed head injury in the mouse.
-
Extracellular superoxide dismutase overexpression protects against aging-induced cognitive impairment in mice.
-
Extracellular superoxide dismutase protects lung development in hyperoxia-exposed newborn mice.
-
Extracellular superoxide dismutase regulates cardiac function and fibrosis.
-
Extracellular superoxide dismutase transgene overexpression preserves postischemic myocardial function in isolated murine hearts.
-
Extracellular superoxide dismutase, nitric oxide, and central nervous system O2 toxicity.
-
Extracellular-signal regulated kinase 1-dependent metabotropic glutamate receptor 5-induced long-term depression in the bed nucleus of the stria terminalis is disrupted by cocaine administration.
-
Extrarenal Signs of Proximal Renal Tubular Acidosis Persist in Nonacidemic Nbce1b/c-Null Mice.
-
Extreme obesity due to impaired leptin signaling in mice does not cause knee osteoarthritis.
-
Ezrin binding domain-deficient NHERF attenuates cAMP-mediated inhibition of Na(+)/H(+) exchange in OK cells.
-
F-actin aggregates in transformed cells.
-
FAT10: a novel mediator of Vpr-induced apoptosis in human immunodeficiency virus-associated nephropathy.
-
FGF14 regulates presynaptic Ca2+ channels and synaptic transmission.
-
FGF2 suppresses neuronogenesis of a cell line derived from rat olfactory epithelium.
-
FGF21-FGFR1 Coordinates Phospholipid Homeostasis, Lipid Droplet Function, and ER Stress in Obesity.
-
FGF21-FGFR4 signaling in cardiac myocytes promotes concentric cardiac hypertrophy in mouse models of diabetes.
-
FGF23 induces left ventricular hypertrophy.
-
FGF23/FGFR4-mediated left ventricular hypertrophy is reversible.
-
FGF9 promotes survival of germ cells in the fetal testis.
-
FGFR4 blockade exerts distinct antitumorigenic effects in human embryonal versus alveolar rhabdomyosarcoma.
-
FGFR4 does not contribute to progression of chronic kidney disease.
-
FKBP12 is not required for the modulation of transforming growth factor beta receptor I signaling activity in embryonic fibroblasts and thymocytes.
-
FKBP12 is the only FK506 binding protein mediating T-cell inhibition by the immunosuppressant FK506.
-
FMRP targets distinct mRNA sequence elements to regulate protein expression.
-
FOXN1 compound heterozygous mutations cause selective thymic hypoplasia in humans.
-
FOXO1 regulates uterine epithelial integrity and progesterone receptor expression critical for embryo implantation.
-
FOXO3 growth inhibition of colonic cells is dependent on intraepithelial lipid droplet density.
-
FRA1 promotes squamous cell carcinoma growth and metastasis through distinct AKT and c-Jun dependent mechanisms.
-
FRAP analysis reveals stabilization of adhesion structures in the epidermis compared to cultured keratinocytes.
-
FRET efficiency measurement in a molecular tension probe with a low-cost frequency-domain fluorescence lifetime imaging microscope.
-
FTY720 stimulates multidrug transporter- and cysteinyl leukotriene-dependent T cell chemotaxis to lymph nodes.
-
FXR1 splicing is important for muscle development and biomolecular condensates in muscle cells.
-
Facilitative glucose transporter Glut1 is actively excluded from rod outer segments.
-
Facultative role of germinal centers and T cells in the somatic diversification of IgVH genes.
-
Failure of 2-deoxy-D-glucose to stimulate feeding in deermice.
-
Failure of red blood cell maturation in mice with defects in the high-density lipoprotein receptor SR-BI.
-
Failure of spermatogenesis in mouse lines deficient in the Na(+)-K(+)-2Cl(-) cotransporter.
-
Failure of terminal erythroid differentiation in EKLF-deficient mice is associated with cell cycle perturbation and reduced expression of E2F2.
-
Failure of ventral body wall closure in mouse embryos lacking a procollagen C-proteinase encoded by Bmp1, a mammalian gene related to Drosophila tolloid.
-
Failure to induce apoptosis via BCL-2 family proteins underlies lack of efficacy of combined MEK and PI3K inhibitors for KRAS-mutant lung cancers.
-
Familial erythrocytosis associated with a short deletion in the erythropoietin receptor gene.
-
Familial polycythemia due to truncations of the erythropoietin receptor.
-
Fas activity mediates airway inflammation during mouse adenovirus type 1 respiratory infection.
-
Fas on renal parenchymal cells does not promote autoimmune nephritis in MRL mice.
-
Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations.
-
Fas/FasL play a central role in pancreatitis-induced hepatocyte apoptosis.
-
Fasciated nerve-muscle explants for in vitro comparison of magnetic and electrical neuromuscular stimulation.
-
Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2(+) Breast Cancer.
-
Fast acquisition and reconstruction of optical coherence tomography images via sparse representation.
-
Fast and robust active neuron segmentation in two-photon calcium imaging using spatiotemporal deep learning.
-
Fast serotonin voltammetry as a versatile tool for mapping dynamic tissue architecture: I. Responses at carbon fibers describe local tissue physiology.
-
Fast voice-coil scanning optical-resolution photoacoustic microscopy.
-
Fasting prevents experimental murine colitis produced by dextran sulfate sodium and decreases interleukin-1 beta and insulin-like growth factor I messenger ribonucleic acid.
-
Fasudil decreases lesion burden in a murine model of cerebral cavernous malformation disease.
-
Fat hormones pull their weight in the CNS.
-
Fat, carbohydrate, and calories in the development of diabetes and obesity in the C57BL/6J mouse.
-
Fate Mapping In Vivo to Distinguish Bona Fide Microglia Versus Recruited Monocyte-Derived Macrophages in Retinal Disease.
-
Fate mapping reveals that microglia and recruited monocyte-derived macrophages are definitively distinguishable by phenotype in the retina.
-
Fate-mapping evidence that hepatic stellate cells are epithelial progenitors in adult mouse livers.
-
Fatty acid desaturase activity in mature red blood cells and implications for blood storage quality.
-
Fatty acid elongase-5 (Elovl5) regulates hepatic triglyceride catabolism in obese C57BL/6J mice.
-
Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. Evidence for compensatory regulation by PPAR delta.
-
Fatty acid synthesis is essential for survival of Cryptococcus neoformans and a potential fungicidal target.
-
Fatty acid transport protein 2 reprograms neutrophils in cancer.
-
Fatty liver vulnerability to endotoxin-induced damage despite NF-kappaB induction and inhibited caspase 3 activation.
-
Fc-mOX40L fusion protein produces complete remission and enhanced survival in 2 murine tumor models.
-
Fc-modified HIT-like monoclonal antibody as a novel treatment for sepsis.
-
Fear and anxiety from principle to practice: implications for when to treat youth with anxiety disorders.
-
Feasibility of whole-body functional mouse imaging using helical pinhole SPECT.
-
Fecal IgA, Antigen Absorption, and Gut Microbiome Composition Are Associated With Food Antigen Sensitization in Genetically Susceptible Mice.
-
Feedback in the brainstem: an excitatory disynaptic pathway for control of whisking.
-
Feedforward mechanisms of cross-orientation interactions in mouse V1.
-
Feeding diversified protein sources exacerbates hepatic insulin resistance via increased gut microbial branched-chain fatty acids and mTORC1 signaling in obese mice.
-
Female fertility is reduced in mice lacking Ca2+/calmodulin-dependent protein kinase IV.
-
Female gender, estrogen loss, and Sub-RPE deposit formation in aged mice.
-
Female steroid hormones use signal transducers and activators of transcription protein-mediated pathways to modulate the expression of T-bet in epithelial cells: a mechanism for local immune regulation in the human reproductive tract.
-
Fenestrations of sarcoplasmic reticulum. Delineation by lanthanum acting as a fortuitous tracer and in situ negative stain.
-
Fenofibrate rapidly decreases hepatic lipid and glycogen storage in neonatal mice with glycogen storage disease type Ia.
-
Ferric citrate reduces fibroblast growth factor 23 levels and improves renal and cardiac function in a mouse model of chronic kidney disease.
-
Ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells in maladaptive renal repair.
-
Ferroxidase hephaestin's cell-autonomous role in the retinal pigment epithelium.
-
Fetal alveolar epithelial cells contain [D-Ala(2)]-deltorphin I-like immunoreactivity: delta- and mu-opiate receptors mediate opposite effects in developing lung.
-
Fetal and adult hematopoietic stem cells give rise to distinct T cell lineages in humans.
-
Fetal antisense oligonucleotide therapy for congenital deafness and vestibular dysfunction.
-
Fetal brain subdivisions defined by R- and E-cadherin expressions: evidence for the role of cadherin activity in region-specific, cell-cell adhesion.
-
Fetal development of subcutaneous white adipose tissue is dependent on Zfp423.
-
Fetal exposure to the maternal microbiota in humans and mice.
-
Fetal mast cells mediate postnatal allergic responses dependent on maternal IgE.
-
Fezf2 regulates telencephalic precursor differentiation from mouse embryonic stem cells.
-
Fgf8 is required for anterior heart field development.
-
Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determination.
-
Fgf9 induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination.
-
Fiber-optic detector for real time dosimetry of a micro-planar x-ray beam.
-
Fiber-optic stethoscope: a cardiac monitoring and gating system for magnetic resonance microscopy.
-
Fibrinogen-Coated Albumin Nanospheres Prevent Thrombocytopenia-Related Bleeding.
-
Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung.
-
Fibroblast growth factor 21 mediates specific glucagon actions.
-
Fibroblast growth factor 23 directly targets hepatocytes to promote inflammation in chronic kidney disease.
-
Fibroblast growth factor 23 is not associated with and does not induce arterial calcification.
-
Fibroblast growth factor blocks Sonic hedgehog signaling in neuronal precursors and tumor cells.
-
Fibroblast growth factor homologous factor 13 regulates Na+ channels and conduction velocity in murine hearts.
-
Fibroblast growth factor homologous factors in the heart: a potential locus for cardiac arrhythmias.
-
Fibroblast growth factor homologous factors modulate cardiac calcium channels.
-
Fibroblast growth factor homologous factors tune arrhythmogenic late NaV1.5 current in calmodulin binding-deficient channels.
-
Fibroblast growth factor receptor 2 regulates proliferation and Sertoli differentiation during male sex determination.
-
Fibroblast growth factor receptor 4: the missing link between chronic kidney disease and FGF23-induced left ventricular hypertrophy?
-
Fibroblast growth factor-21 is required for weight loss induced by the glucagon-like peptide-1 receptor agonist liraglutide in male mice fed high carbohydrate diets.
-
Fibroblast growth factor-23-mediated inhibition of renal phosphate transport in mice requires sodium-hydrogen exchanger regulatory factor-1 (NHERF-1) and synergizes with parathyroid hormone.
-
Fibrogenesis in pancreatic cancer is a dynamic process regulated by macrophage-stellate cell interaction.
-
Fibronectin Extra Domain A Promotes Liver Sinusoid Repair following Hepatectomy.
-
Fibronectin and beta-catenin act in a regulatory loop in dermal fibroblasts to modulate cutaneous healing.
-
Fibulin-2 is a driver of malignant progression in lung adenocarcinoma.
-
Fibulin-3 is a novel TGF-β pathway inhibitor in the breast cancer microenvironment.
-
Filaggrin deficiency promotes the dissemination of cutaneously inoculated vaccinia virus.
-
Finale: the last minutes of Smads.
-
Fine mapping of a putative rd cDNA and its co-segregation with rd expression.
-
Fine mapping, gene content, comparative sequencing, and expression analyses support Ctla4 and Nramp1 as candidates for Idd5.1 and Idd5.2 in the nonobese diabetic mouse.
-
Fine time course expression analysis identifies cascades of activation and repression and maps a putative regulator of mammalian sex determination.
-
First evidence that γ-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine in a xenograft mouse model through the modulation of NF-κB pathway.
-
First in human dose calculation of a single-chain bispecific antibody targeting glioma using the MABEL approach.
-
Fish oil feeding modulates leukotriene production in murine lupus nephritis.
-
Fish oil slows prostate cancer xenograft growth relative to other dietary fats and is associated with decreased mitochondrial and insulin pathway gene expression.
-
Fitm2 is required for ER homeostasis and normal function of murine liver.
-
Flanking nuclear matrix attachment regions synergize with the T cell receptor delta enhancer to promote V(D)J recombination.
-
Flavanones structure-related inhibition on TPA-induced tumor promotion through suppression of extracellular signal-regulated protein kinases: involvement of prostaglandin E2 in anti-promotive process.
-
Flavivirus serocomplex cross-reactive immunity is protective by activating heterologous memory CD4 T cells.
-
Flavonoids. 8. Synthesis and antifertility and estrogen receptor binding activities of coumarins and delta3-isoflavenes.
-
Flavopiridol induces apoptosis in chronic lymphocytic leukemia cells via activation of caspase-3 without evidence of bcl-2 modulation or dependence on functional p53.
-
Flow Cytometric Identification of Tumor-Infiltrating Lymphocytes from Glioblastoma.
-
Flow Cytometry for the Immunotoxicologist.
-
Flow cytometric detection of lymphocyte proliferation in eyes with immunogenic inflammation.
-
Flow cytometry sorting of recombinant mycobacterial species yields bacterial clones with enhanced insert expression.
-
Flow velocity in the superficial lymphatic network of the mouse tail.
-
Flow-dependent epigenetic DNA methylation regulates endothelial gene expression and atherosclerosis
-
Fluconazole Monotherapy Is a Suboptimal Option for Initial Treatment of Cryptococcal Meningitis Because of Emergence of Resistance.
-
Flunarizine enhancement of melphalan activity against drug-sensitive/resistant rhabdomyosarcoma.
-
Fluorescence imaging of GABAA receptor-mediated intracellular [Cl-] in P19-N cells reveals unique pharmacological properties.
-
Fluorescence linked enzyme chemoproteomic strategy for discovery of a potent and selective DAPK1 and ZIPK inhibitor.
-
Fluorescence ratio imaging of interstitial pH in solid tumours: effect of glucose on spatial and temporal gradients.
-
Fluorescence staining of the actin cytoskeleton in living cells with 7-nitrobenz-2-oxa-1,3-diazole-phallacidin.
-
Fluorescence-based alternative splicing reporters for the study of epithelial plasticity in vivo.
-
Fluorescent probes that stain living nerve terminals.
-
Fluorine-18 Labeling of the HER2-Targeting Single-Domain Antibody 2Rs15d Using a Residualizing Label and Preclinical Evaluation.
-
Fluorine-18 Labeling of the MDM2 Inhibitor RG7388 for PET Imaging: Chemistry and Preliminary Evaluation.
-
Fluorine-18 labeled chemotactic peptides: a potential approach for the PET imaging of bacterial infection.
-
Fluorine-18 labeling of an anti-HER2 VHH using a residualizing prosthetic group via a strain-promoted click reaction: Chemistry and preliminary evaluation.
-
Fluorine-18 labeling of monoclonal antibodies and fragments with preservation of immunoreactivity.
-
Fluorine-18-labeled [Nle4,D-Phe7]-alpha-MSH, an alpha-melanocyte stimulating hormone analogue.
-
Fluorine-18-labeled monoclonal antibody fragments: a potential approach for combining radioimmunoscintigraphy and positron emission tomography.
-
Fluoxetine Maintains a State of Heightened Responsiveness to Motor Training Early After Stroke in a Mouse Model.
-
Fluvastatin downregulates VEGF-A expression in TNF-α-induced retinal vessel tortuosity.
-
Focal adhesion kinase mediates the interferon-gamma-inducible GTPase-induced phosphatidylinositol 3-kinase/Akt survival pathway and further initiates a positive feedback loop of NF-kappaB activation.
-
Folate-targeted nanoparticle delivery of chemo- and radiotherapeutics for the treatment of ovarian cancer peritoneal metastasis.
-
Follicle-Stimulating Hormone Receptor Is Expressed by Most Ovarian Cancer Subtypes and Is a Safe and Effective Immunotherapeutic Target.
-
Follistatin in chondrocytes: the link between TRPV4 channelopathies and skeletal malformations.
-
Follistatin operates downstream of Wnt4 in mammalian ovary organogenesis.
-
Food reward in the absence of taste receptor signaling.
-
Food-Grade TiO2
Particles Generate Intracellular Superoxide and Alter Epigenetic Modifiers in Human Lung Cells.
-
Force fluctuations in three-dimensional suspended fibroblasts.
-
Force plate for measuring the ground reaction forces in small animal locomotion.
-
Force-frequency effect is a powerful determinant of myocardial contractility in the mouse.
-
Formation of DNA-protein cross-links in cultured mammalian cells upon treatment with iron ions.
-
Formation of Rathke's pouch requires dual induction from the diencephalon.
-
Formation of precise connections in the olfactory bulb occurs in the absence of odorant-evoked neuronal activity.
-
Formation of retinal direction-selective circuitry initiated by starburst amacrine cell homotypic contact.
-
Formation of telomeric repeat-containing RNA (TERRA) foci in highly proliferating mouse cerebellar neuronal progenitors and medulloblastoma.
-
Formation of α-synuclein Lewy neurite-like aggregates in axons impedes the transport of distinct endosomes.
-
Formin-like 1 mediates effector T cell trafficking to inflammatory sites to enable T cell-mediated autoimmunity.
-
Formulations which increase the size of lipoplexes prevent serum-associated inhibition of transfection.
-
Four-Point Bending Testing for Mechanical Assessment of Mouse Bone Structural Properties.
-
Four-dimensional MR microscopy of the mouse heart using radial acquisition and liposomal gadolinium contrast agent.
-
Four-dimensional MRI of renal function in the developing mouse.
-
Four-dimensional analysis of vascularization during primary development of an organ, the gonad.
-
FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start site.
-
FoxJ1-dependent gene expression is required for differentiation of radial glia into ependymal cells and a subset of astrocytes in the postnatal brain.
-
FoxO-dependent regulation of diacylglycerol kinase α gene expression.
-
FoxO1 deacetylation regulates thyroid hormone-induced transcription of key hepatic gluconeogenic genes.
-
Foxa1-deficient mice exhibit impaired insulin secretion due to uncoupled oxidative phosphorylation.
-
Foxp1 Is Indispensable for Ductal Morphogenesis and Controls the Exit of Mammary Stem Cells from Quiescence.
-
Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression.
-
Frame-Hydrogel Methodology for Engineering Highly Functional Cardiac Tissue Constructs.
-
Framework Mutations of the 10-1074 bnAb Increase Conformational Stability, Manufacturability, and Stability While Preserving Full Neutralization Activity.
-
Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K.
-
Frequent expression of human carcinoma-associated antigen, a mucin-type glycoprotein, in cells of prostatic carcinoma.
-
From breast to the brain: unraveling the puzzle of metastasis organotropism.
-
From embryo to ethics: a career in science and social responsibility. An interview with Anne McLarne [by Brigid Hogan].
-
From embryo to teratocarcinoma in tissue culture.
-
From induction to conduction: how intrinsic transcriptional priming of extrinsic neuronal connectivity shapes neuronal identity.
-
From the yolk sac to the spleen: New roles for Notch in regulating hematopoiesis.
-
Frontline Science: Multiple cathepsins promote inflammasome-independent, particle-induced cell death during NLRP3-dependent IL-1β activation.
-
Fructose and glucose can regulate mammalian target of rapamycin complex 1 and lipogenic gene expression via distinct pathways.
-
Fructose consumption as a risk factor for non-alcoholic fatty liver disease.
-
Fulfilling Koch's postulates of autoimmunity: anti-NR2 antibodies in mice and men.
-
Full Spectrum of LPS Activation in Alveolar Macrophages of Healthy Volunteers by Whole Transcriptomic Profiling.
-
Full genetic rescue of adenosine deaminase-deficient mice through introduction of the human gene.
-
Full-length dystrophin restoration via targeted exon integration by AAV-CRISPR in a humanized mouse model of Duchenne muscular dystrophy.
-
Fully implantable and bioresorbable cardiac pacemakers without leads or batteries.
-
Fumonisin B1 inhibits sphingosine (sphinganine) N-acyltransferase and de novo sphingolipid biosynthesis in cultured neurons in situ.
-
Fumonisins disrupt sphingolipid metabolism, folate transport, and neural tube development in embryo culture and in vivo: a potential risk factor for human neural tube defects among populations consuming fumonisin-contaminated maize.
-
Function and regulation of calmodulin in endocrine cells.
-
Function in athymic nude mice of parathyroid heterografts from patients with primary hyperparathyroidism and secondary hyperparathyroidism.
-
Function of nuclear factor kappaB in pancreatic cancer metastasis.
-
Function of tau protein in adult newborn neurons.
-
Function of the thioredoxin proteins in Cryptococcus neoformans during stress or virulence and regulation by putative transcriptional modulators.
-
Functional Genomic Analyses of Mendelian and Sporadic Disease Identify Impaired eIF2α Signaling as a Generalizable Mechanism for Dystonia.
-
Functional Interplay between Histone H2B ADP-Ribosylation and Phosphorylation Controls Adipogenesis.
-
Functional TRPV4 channels are expressed in mouse skeletal muscle and can modulate resting Ca2+ influx and muscle fatigue.
-
Functional alterations of macrophages in autoimmune MRL-lpr/lpr mice.
-
Functional analysis of a mammalian odorant receptor subfamily.
-
Functional analysis of myocardial performance in murine hearts overexpressing the human beta 2-adrenergic receptor.
-
Functional analysis of novel SNPs and mutations in human and mouse genomes.
-
Functional analysis of the TAN-1 gene, a human homolog of Drosophila notch.
-
Functional analysis of the interface between the tandem C2 domains of synaptotagmin-1.
-
Functional analysis of the putative integrin recognition motif on adeno-associated virus 9.
-
Functional and molecular adaptations in skeletal muscle of myoglobin-mutant mice.
-
Functional and molecular characterization of human monoclonal antibody reactive with the immunodominant region of HIV type 1 glycoprotein 41.
-
Functional association of CD7 with phosphatidylinositol 3-kinase: interaction via a YEDM motif.
-
Functional characteristics and survival requirements of memory CD4+ T lymphocytes in vivo.
-
Functional comparison of RGS9 splice isoforms in a living cell.
-
Functional complementation between FADD and RIP1 in embryos and lymphocytes.
-
Functional consequences of altering myocardial adrenergic receptor signaling.
-
Functional diversity of notch family genes in fetal lung development.
-
Functional domain and motif analyses of androgen receptor coregulator ARA70 and its differential expression in prostate cancer.
-
Functional epialleles at an endogenous human centromere.
-
Functional evaluation of nonphagocytic NAD(P)H oxidases.
-
Functional evolution of mammalian odorant receptors.
-
Functional expression of Mammalian odorant receptors.
-
Functional expression of sodium-glucose transporters in cancer.
-
Functional expression of the multidrug resistance-associated protein in the yeast Saccharomyces cerevisiae.
-
Functional genetic screen of human diversity reveals that a methionine salvage enzyme regulates inflammatory cell death.
-
Functional genomics of the beta-cell: short-chain 3-hydroxyacyl-coenzyme A dehydrogenase regulates insulin secretion independent of K+ currents.
-
Functional imaging of tumor vasculature using iodine and gadolinium-based nanoparticle contrast agents: a comparison of spectral micro-CT using energy integrating and photon counting detectors.
-
Functional interaction between trace amine-associated receptor 1 and dopamine D2 receptor.
-
Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development.
-
Functional neuroimaging using ultrasonic blood-brain barrier disruption and manganese-enhanced MRI.
-
Functional organization of the genome may shape the species boundary in the house mouse.
-
Functional photoacoustic microscopy of diabetic vasculature.
-
Functional photoacoustic microscopy of pH.
-
Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis.
-
Functional replacement of the mouse E2A gene with a human HEB cDNA.
-
Functional screen identifies kinases driving prostate cancer visceral and bone metastasis.
-
Functional selection of protease inhibitory antibodies.
-
Functional specialization of mouse higher visual cortical areas.
-
Functional transient receptor potential vanilloid 1 and transient receptor potential vanilloid 4 channels along different segments of the renal vasculature.
-
Functional vagotopy in the cervical vagus nerve of the domestic pig: implications for the study of vagus nerve stimulation.
-
Functional variants in TBX2 are associated with a syndromic cardiovascular and skeletal developmental disorder.
-
Functional, non-clonal IgMa-restricted B cell receptor interactions with the HIV-1 envelope gp41 membrane proximal external region.
-
Functionally Overlapping Variants Control Tuberculosis Susceptibility in Collaborative Cross Mice.
-
Functionally graded multilayer scaffolds for in vivo osteochondral tissue engineering.
-
Functions of E2A-HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEB.
-
Functions of MutLalpha, replication protein A (RPA), and HMGB1 in 5'-directed mismatch repair.
-
Functions of skin-resident γδ T cells.
-
Fungal homoserine kinase (thr1Delta) mutants are attenuated in virulence and die rapidly upon threonine starvation and serum incubation.
-
Further Advances in Optimizing (2-Phenylcyclopropyl)methylamines as Novel Serotonin 2C Agonists: Effects on Hyperlocomotion, Prepulse Inhibition, and Cognition Models.
-
Further characterization of the oncornavirus inactivating factor in normal mouse serum.
-
Further characterization of the platinum-reactive component of the alpha 2-macroglobulin-receptor recognition site.
-
Further studies of a macrophage chemotaxis inhibitor (MCI) produced by neoplasms: murine tumors free of lactic dehydrogenase virus produce MCI.
-
Fusigenic viral liposome for gene therapy in cardiovascular diseases.
-
Fusion of fibroblast growth factor 21 to a thermally responsive biopolymer forms an injectable depot with sustained anti-diabetic action.
-
Fusion of the termini of the murine cytomegalovirus genome after infection.
-
Fusobacterium nucleatum induces premature and term stillbirths in pregnant mice: implication of oral bacteria in preterm birth.
-
Future directions in idiopathic pulmonary fibrosis research. An NHLBI workshop report.
-
Future translational applications from the contemporary genomics era: a scientific statement from the American Heart Association.
-
G Protein Coupled Receptor Kinase 3 Regulates Breast Cancer Migration, Invasion, and Metastasis.
-
G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway.
-
G protein G(alpha)o is essential for vomeronasal function and aggressive behavior in mice.
-
G protein- and β-arrestin Signaling Profiles of Endothelin Derivatives at the Type A Endothelin Receptor.
-
G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophy.
-
G protein-coupled receptor internalization signaling is required for cardioprotection in ischemic preconditioning.
-
G protein-coupled receptor kinase 3 (GRK3) gene disruption leads to loss of odorant receptor desensitization.
-
G protein-coupled receptor kinase 3 modulates mesenchymal stem cell proliferation and differentiation through sphingosine-1-phosphate receptor regulation.
-
G protein-coupled receptor kinase 5 regulates airway responses induced by muscarinic receptor activation.
-
G protein-coupled receptor kinase-3-deficient mice exhibit WHIM syndrome features and attenuated inflammatory responses.
-
G protein-coupled receptor kinase-5 attenuates atherosclerosis by regulating receptor tyrosine kinases and 7-transmembrane receptors.
-
G(s)alpha deficiency in adipose tissue leads to a lean phenotype with divergent effects on cold tolerance and diet-induced thermogenesis.
-
G(s)alpha deficiency in skeletal muscle leads to reduced muscle mass, fiber-type switching, and glucose intolerance without insulin resistance or deficiency.
-
G-protein receptor kinase 3 (GRK3) influences opioid analgesic tolerance but not opioid withdrawal.
-
G-protein signaling modulator-3, a gene linked to autoimmune diseases, regulates monocyte function and its deficiency protects from inflammatory arthritis.
-
G-protein-coupled receptor function in heart failure.
-
G-protein-coupled receptor genes as protooncogenes: constitutively activating mutation of the alpha 1B-adrenergic receptor enhances mitogenesis and tumorigenicity.
-
G1T48, an oral selective estrogen receptor degrader, and the CDK4/6 inhibitor lerociclib inhibit tumor growth in animal models of endocrine-resistant breast cancer.
-
G2019S-LRRK2 Expression Augments α-Synuclein Sequestration into Inclusions in Neurons.
-
GABA receptor-mediated chloride transport in a "cell-free" membrane preparation from brain.
-
GABA signaling promotes synapse elimination and axon pruning in developing cortical inhibitory interneurons.
-
GABAergic pathway from zona incerta to neocortex: clarification.
-
GAD67-mediated GABA synthesis and signaling regulate inhibitory synaptic innervation in the visual cortex.
-
GATA2 regulates body water homeostasis through maintaining aquaporin 2 expression in renal collecting ducts.
-
GATA4 and the two sides of gene expression reprogramming.
-
GATA6 levels modulate primitive endoderm cell fate choice and timing in the mouse blastocyst.
-
GB virus type C envelope protein E2 elicits antibodies that react with a cellular antigen on HIV-1 particles and neutralize diverse HIV-1 isolates.
-
GD3 expression by cultured human tumor cells of neuroectodermal origin.
-
GENIS: gene expression of sodium iodide symporter for noninvasive imaging of gene therapy vectors and quantification of gene expression in vivo.
-
GFAP is necessary for the integrity of CNS white matter architecture and long-term maintenance of myelination.
-
GFRα1 released by nerves enhances cancer cell perineural invasion through GDNF-RET signaling.
-
GGTase-I deficiency reduces tumor formation and improves survival in mice with K-RAS-induced lung cancer.
-
GIPR Is Predominantly Localized to Nonadipocyte Cell Types Within White Adipose Tissue.
-
GIT1 regulates synaptic structural plasticity underlying learning.
-
GLP toxicology study of a fully-human T cell redirecting CD3:EGFRvIII binding immunotherapeutic bispecific antibody.
-
GLP-1 receptor activation indirectly reduces hepatic lipid accumulation but does not attenuate development of atherosclerosis in diabetic male ApoE(-/-) mice.
-
GLUT1 Expression in Tumor-Associated Neutrophils Promotes Lung Cancer Growth and Resistance to Radiotherapy.
-
GM-CSF inhibition reduces cytokine release syndrome and neuroinflammation but enhances CAR-T cell function in xenografts.
-
GMab-1, a high-affinity anti-3'-isoLM1/3',6'-isoLD1 IgG monoclonal antibody, raised in lacto-series ganglioside-defective knockout mice.
-
GNA13 expression promotes drug resistance and tumor-initiating phenotypes in squamous cell cancers.
-
GNA13 loss in germinal center B cells leads to impaired apoptosis and promotes lymphoma in vivo.
-
GPER1 is required to protect fetal health from maternal inflammation.
-
GPR158 in the Visual System: Homeostatic Role in Regulation of Intraocular Pressure.
-
GPR171 is a hypothalamic G protein-coupled receptor for BigLEN, a neuropeptide involved in feeding.
-
GPR37 regulates macrophage phagocytosis and resolution of inflammatory pain.
-
GPR54 is a target for suppression of metastasis in endometrial cancer.
-
GPR92 activation in islet macrophages controls β cell function in a diet-induced obesity model.
-
GQ-16, a novel peroxisome proliferator-activated receptor γ (PPARγ) ligand, promotes insulin sensitization without weight gain.
-
GREAT improves functional interpretation of cis-regulatory regions.
-
GRHL2 coordinates regeneration of a polarized mucociliary epithelium from basal stem cells.
-
GRP94 (gp96) and GRP94 N-terminal geldanamycin binding domain elicit tissue nonrestricted tumor suppression.
-
GRP94-associated enzymatic activities. Resolution by chromatographic fractionation.
-
GRP94/gp96 elicits ERK activation in murine macrophages. A role for endotoxin contamination in NF-kappa B activation and nitric oxide production.
-
GSK2193874 treatment at heatstroke onset reduced cell apoptosis in heatstroke mice.
-
GUCY2C Signaling Opposes the Acute Radiation-Induced GI Syndrome.
-
GUCY2C opposes systemic genotoxic tumorigenesis by regulating AKT-dependent intestinal barrier integrity.
-
Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesis.
-
Gadolinium-conjugated gold nanoshells for multimodal diagnostic imaging and photothermal cancer therapy.
-
Gain of glucose-independent growth upon metastasis of breast cancer cells to the brain.
-
Galbraith Award: simvastatin attenuates experimental cerebral vasospasm and ameliorates serum markers of neuronal and endothelial injury in patients after subarachnoid hemorrhage: a dose-response effect dependent on endothelial nitric oxide synthase.
-
Galectin-1 drives lymphoma CD20 immunotherapy resistance: validation of a preclinical system to identify resistance mechanisms.
-
Galectin-1 is essential for the induction of MOG35-55 -based intravenous tolerance in experimental autoimmune encephalomyelitis.
-
Galectin-3 as a Therapeutic Target for NSAID-Induced Intestinal Ulcers.
-
Galectin-3 directs antimicrobial guanylate binding proteins to vacuoles furnished with bacterial secretion systems.
-
Gallbladder glycoprotein secretion in mice with hemolytic anemia and pigment gallstones.
-
Galphaq-dependent signaling cascades stimulate water-seeking behavior.
-
Galphaz negatively regulates insulin secretion and glucose clearance.
-
Gamma delta T cell help of B cells is induced by repeated parasitic infection, in the absence of other T cells.
-
Gamma interferon-induced inhibition of Toxoplasma gondii in astrocytes is mediated by IGTP.
-
Gamma-globin gene promoter elements required for interaction with globin enhancers.
-
Gamma-irradiation reduces the allogenicity of donor corneas.
-
Gammaherpesvirus modulation of mouse adenovirus type 1 pathogenesis.
-
Gammaherpesvirus-induced lung pathology is altered in the absence of macrophages.
-
Ganglioside mapping of a human medulloblastoma xenograft.
-
Gap Junctions Contribute to Differential Light Adaptation across Direction-Selective Retinal Ganglion Cells.
-
Garlic accelerates red blood cell turnover and splenic erythropoietic gene expression in mice: evidence for erythropoietin-independent erythropoiesis.
-
Gastroesophageal reflux-associated aspiration alters the immune response in asthma.
-
Gastrointestinal microbiota alteration induced by Mucor circinelloides in a murine model.
-
Gata3 loss leads to embryonic lethality due to noradrenaline deficiency of the sympathetic nervous system.
-
Gbetagamma-dependent phosphoinositide 3-kinase activation in hearts with in vivo pressure overload hypertrophy.
-
Gelatin-embedded cell-polymer constructs for histological cryosectioning.
-
Gender and estrogen supplementation increases severity of experimental choroidal neovascularization.
-
Gender differences in human immunodeficiency virus type 1-specific CD8 responses in the reproductive tract and colon following nasal peptide priming and modified vaccinia virus Ankara boosting.
-
Gender-specific patterns of left ventricular and myocyte remodeling following myocardial infarction in mice deficient in the angiotensin II type 1a receptor.
-
Gene Delivery of a Caspase Activation and Recruitment Domain Improves Retinal Pigment Epithelial Function and Modulates Inflammation in a Mouse Model with Features of Dry Age-Related Macular Degeneration.
-
Gene Expression Profile of Dendritic Cell-Tumor Cell Hybrids Determined by Microarrays and Its Implications for Cancer Immunotherapy.
-
Gene Expression Profiling of Cutaneous Injured and Non-Injured Nociceptors in SNI Animal Model of Neuropathic Pain.
-
Gene Expression of Diverse Cryptococcus Isolates during Infection of the Human Central Nervous System.
-
Gene Therapy for Modulation of T-Cell-Mediated Immune Response Provoked by Corneal Transplantation.
-
Gene and protein expression pilot profiling and biomarkers in an experimental mouse model of hypertensive glaucoma.
-
Gene by sex interaction in the etiology of coronary heart disease and the preceding metabolic syndrome.
-
Gene conversion in the absence of reciprocal recombination.
-
Gene delivery through cell culture substrate adsorbed DNA complexes
-
Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300.
-
Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP.
-
Gene duplications at the chemokine locus on mouse chromosome 4: multiple strain-specific haplotypes and the deletion of secondary lymphoid-organ chemokine and EBI-1 ligand chemokine genes in the plt mutation.
-
Gene expression analysis of purified hematopoietic stem cells and committed progenitors.
-
Gene expression phenotypes of oncogenic signaling pathways.
-
Gene expression phenotypic models that predict the activity of oncogenic pathways.
-
Gene expression profiles linked to AT1 angiotensin receptors in the kidney.
-
Gene expression profiles of RAW264.7 macrophages stimulated with preparations of LPS differing in isolation and purity.
-
Gene expression profiling of familial and sporadic interstitial pneumonia.
-
Gene expression profiling of mouse bladder inflammatory responses to LPS, substance P, and antigen-stimulation.
-
Gene expression profiling reveals progesterone-mediated cell cycle and immunoregulatory roles of Hoxa-10 in the preimplantation uterus.
-
Gene expression signatures of radiation response are specific, durable and accurate in mice and humans.
-
Gene expression signatures that predict radiation exposure in mice and humans.
-
Gene expression-based classifiers identify Staphylococcus aureus infection in mice and humans.
-
Gene knockouts of c-src, transforming growth factor beta 1, and tenascin suggest superfluous, nonfunctional expression of proteins.
-
Gene silencing using RNA interference in embryonic stem cells.
-
Gene targeting in mice reveals a requirement for angiotensin in the development and maintenance of kidney morphology and growth factor regulation.
-
Gene targeting in physiological investigations: studies of the renin-angiotensin system.
-
Gene targeting to the ROSA26 locus directed by engineered zinc finger nucleases
-
Gene targeting. Getting nearer the mark.
-
Gene therapies that restore dystrophin expression for the treatment of Duchenne muscular dystrophy.
-
Gene therapy in tissue-engineered blood vessels.
-
Gene transfer of pigment epithelium-derived factor suppresses tumor growth and angiogenesis in a hepatoblastoma xenograft model.
-
Gene transfer to the thymus. A means of abrogating the immune response to recombinant adenovirus.
-
Gene-targeting studies of the renin-angiotensin system: mechanisms of hypertension and cardiovascular disease.
-
General anesthetics activate a potent central pain-suppression circuit in the amygdala.
-
General olfactory sensitivity database (GOSdb): candidate genes and their genomic variations.
-
Generation and Characterization of a Cell Type-Specific, Inducible Cre-Driver Line to Study Olfactory Processing.
-
Generation and analysis of partially haploid cells with Cre-mediated chromosome deletion in the lymphoid system.
-
Generation and behavioral characterization of beta-catenin forebrain-specific conditional knock-out mice.
-
Generation and characterization of Tmeff2 mutant mice.
-
Generation and characterization of a complete null estrogen receptor alpha mouse using Cre/LoxP technology.
-
Generation and characterization of a mouse/human chimeric antibody directed against extracellular matrix protein tenascin.
-
Generation and characterization of anti-Adeno-associated virus serotype 8 (AAV8) and anti-AAV9 monoclonal antibodies.
-
Generation and characterization of mice lacking gastrin-releasing peptide receptor.
-
Generation and comparison of CRISPR-Cas9 and Cre-mediated genetically engineered mouse models of sarcoma.
-
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
-
Generation of CAR T cells for adoptive therapy in the context of glioblastoma standard of care.
-
Generation of CD8+ T-cell responses by a recombinant nonpathogenic Mycobacterium smegmatis vaccine vector expressing human immunodeficiency virus type 1 Env.
-
Generation of Dhx9-deficient clones in T-cell development with a mitotic recombination technique.
-
Generation of a Listeria vaccine strain by enhanced caspase-1 activation.
-
Generation of a Magoh conditional allele in mice.
-
Generation of a Mouse Full-length Balancer with Versatile Cassette-shuttling Selection Strategy.
-
Generation of a loxP flanked bmp4loxP-lacZ allele marked by conditional lacZ expression.
-
Generation of a microglial developmental index in mice and in humans reveals a sex difference in maturation and immune reactivity.
-
Generation of a polyclonal Fab phage display library to the protozoan parasite Cryptosporidium parvum.
-
Generation of a polyclonal fab phage display library to the human breast carcinoma cell line BT-20.
-
Generation of a syngeneic mouse model to study the effects of vascular endothelial growth factor in ovarian carcinoma.
-
Generation of anti-idiotypic reagents in the EGFRvIII tumor-associated antigen system.
-
Generation of bone marrow and fetal liver chimeric mice.
-
Generation of hydrogen peroxide and failure of antioxidative responses in pancreatic islets of male C57BL/6 mice are associated with diabetes induced by multiple low doses of streptozotocin.
-
Generation of mucosal anti-human immunodeficiency virus type 1 T-cell responses by recombinant Mycobacterium smegmatis.
-
Generation of neutralizing activity against human immunodeficiency virus type 1 in serum by antibody gene transfer.
-
Generation of normal lymphocyte populations following transplantation of adenosine-deaminase-deficient fetal liver cells.
-
Generation of orthotopic and heterotopic human pancreatic cancer xenografts in immunodeficient mice.
-
Generation of primary tumor-specific cytotoxic T lymphocytes from autologous and human lymphocyte antigen class I-matched allogeneic peripheral blood lymphocytes by B7 gene-modified melanoma cells.
-
Generation of primary tumors with Flp recombinase in FRT-flanked p53 mice.
-
Generation of recombinant vaccinia virus and analysis of virus-induced cell death.
-
Generation of reovirus core-like particles in cells infected with hybrid vaccinia viruses that express genome segments L1, L2, L3, and S2.
-
Genes for apolipoprotein B and microsomal triglyceride transfer protein are expressed in the heart: evidence that the heart has the capacity to synthesize and secrete lipoproteins.
-
Genes for the neuronal immunoglobulin domain cell adhesion molecules neurofascin and Nr-CAM map to mouse chromosomes 1 and 12 and homologous human chromosomes.
-
Genes that modify the hemochromatosis phenotype in mice.
-
Genesis of the monophasic action potential: role of interstitial resistance and boundary gradients.
-
Genetic Abrogation of Adenosine A3 Receptor Prevents Uninephrectomy and High Salt-Induced Hypertension.
-
Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders.
-
Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model.
-
Genetic Screen in Chlamydia muridarum Reveals Role for an Interferon-Induced Host Cell Death Program in Antimicrobial Inclusion Rupture.
-
Genetic Single Neuron Anatomy Reveals Fine Granularity of Cortical Axo-Axonic Cells.
-
Genetic Variation in Surfactant Protein-A2 Delays Resolution of Eosinophilia in Asthma.
-
Genetic ablation of phosphatidylinositol transfer protein function in murine embryonic stem cells.
-
Genetic alterations that inhibit in vivo pressure-overload hypertrophy prevent cardiac dysfunction despite increased wall stress.
-
Genetic analysis of MRL-lpr mice: relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci.
-
Genetic analysis of intracranial tumors in a murine model of glioma demonstrate a shift in gene expression in response to host immunity.
-
Genetic analysis of susceptibility to Chlamydia trachomatis in mouse.
-
Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease.
-
Genetic and cellular evidence of decreased inflammation associated with reduced incidence of posttraumatic arthritis in MRL/MpJ mice.
-
Genetic and epigenetic inactivation of Kruppel-like factor 4 in medulloblastoma.
-
Genetic and pharmacologic analyses of the role of Icmt in Ras membrane association and function.
-
Genetic and pharmacological validation of TAK1 inhibition in macrophages as a therapeutic strategy to effectively inhibit TNF secretion.
-
Genetic approaches to neural circuits in the mouse.
-
Genetic association study of adiposity and melanocortin-4 receptor (MC4R) common variants: replication and functional characterization of non-coding regions.
-
Genetic background influences cardiac phenotype in murine chronic kidney disease.
-
Genetic basis of murine responses to hyperoxia-induced lung injury.
-
Genetic characterization of a missense mutation in the X-linked TAF7L gene identified in an oligozoospermic man†.
-
Genetic control of blood pressure and the angiotensinogen locus.
-
Genetic control of inflammatory arthritis and glomerulonephritis in congenic lpr mice and their F1 hybrids.
-
Genetic control of inflammatory arthritis in congenic lpr mice.
-
Genetic control of peripheral leukocyte response to endotoxin in mice.
-
Genetic control of the immune response to nuclease. V. Genetic linkage and strain distribution of anti-nuclease idiotypes.
-
Genetic control of the immune response to staphylococcal nuclease in mice.
-
Genetic control of the immune response to staphylococcal nuclease. IX. Recombination between genes determining BALB/c antinuclease idiotypes and the heavy chain allotype locus.
-
Genetic control of the immune response to staphylococcal nuclease. VII. Role of non-H2-linked genes in the control of the anti-nuclease antibody response.
-
Genetic control of the immune response to staphylococcal nuclease. VIII. Mapping of genes for antibodies to different antigenic regions of nuclease.
-
Genetic deficiency of Irgm1 (LRG-47) suppresses induction of experimental autoimmune encephalomyelitis by promoting apoptosis of activated CD4+ T cells.
-
Genetic deletion of A2A adenosine receptors in the striatum selectively impairs habit formation
-
Genetic deletion of Rgs12 in mice affects serotonin transporter expression and function in vivo and ex vivo.
-
Genetic deletion of receptor for hyaluronan-mediated motility (Rhamm) attenuates the formation of aggressive fibromatosis (desmoid tumor).
-
Genetic differences in oxidative stress and inflammatory responses to diet-induced obesity do not alter liver fibrosis in mice.
-
Genetic disruption of WASHC4 drives endo-lysosomal dysfunction and cognitive-movement impairments in mice and humans.
-
Genetic dissection of rod and cone pathways in the dark-adapted mouse retina.
-
Genetic dissection of the glutamatergic neuron system in cerebral cortex.
-
Genetic dissection of the mouse CNS using magnetic resonance microscopy.
-
Genetic dissection of the mouse brain using high-field magnetic resonance microscopy.
-
Genetic elimination of α3(IV) collagen fails to rescue anti-collagen B cells.
-
Genetic engineering of a suboptimal islet graft with A20 preserves beta cell mass and function.
-
Genetic factors determine the contribution of leukotrienes to acute inflammatory responses.
-
Genetic heterogeneity of Myc-induced mammary tumors reflecting diverse phenotypes including metastatic potential.
-
Genetic immunization with LYVE-1 cDNA yields function-blocking antibodies against native protein.
-
Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes.
-
Genetic induction of tumorigenesis in swine.
-
Genetic insights into biological mechanisms governing human ovarian ageing.
-
Genetic interactions between Shox2 and Hox genes during the regional growth and development of the mouse limb.
-
Genetic labeling of neurons in mouse brain.
-
Genetic manipulation of the renin-angiotensin system.
-
Genetic mapping of the beta-arrestin 1 and 2 genes on mouse chromosomes 7 and 11 respectively.
-
Genetic modeling of Ras-induced human rhabdomyosarcoma.
-
Genetic modeling of human rhabdomyosarcoma.
-
Genetic models reveal origin, persistence and non-redundant functions of IL-17-producing γδ T cells.
-
Genetic modification of mesenchymal stem cells overexpressing CCR1 increases cell viability, migration, engraftment, and capillary density in the injured myocardium.
-
Genetic modifier loci affecting survival and cardiac function in murine dilated cardiomyopathy.
-
Genetic modifiers of the Kv beta2-null phenotype in mice.
-
Genetic mosaics reveal both cell-autonomous and cell-nonautonomous function of murine p27Kip1.
-
Genetic networks of liver metabolism revealed by integration of metabolic and transcriptional profiling.
-
Genetic pathway analysis reveals a major role for extracellular matrix organization in inflammatory and neuropathic pain.
-
Genetic polymorphisms: a cornerstone of translational biobehavioral research.
-
Genetic regulation of pristane-induced oil granuloma responses.
-
Genetic resistance to infection influences a male's sexual attractiveness and modulation of testosterone.
-
Genetic susceptibility to benzene-induced toxicity: role of NADPH: quinone oxidoreductase-1.
-
Genetic variants on chromosome 1q41 influence ocular axial length and high myopia.
-
Genetic variation in Mon1a affects protein trafficking and modifies macrophage iron loading in mice.
-
Genetic variation in SP-A2 leads to differential binding to Mycoplasma pneumoniae membranes and regulation of host responses.
-
Genetic vulnerability to diet-induced obesity in the C57BL/6J mouse: physiological and molecular characteristics.
-
Genetically Encoded Stealth Nanoparticles of a Zwitterionic Polypeptide-Paclitaxel Conjugate Have a Wider Therapeutic Window than Abraxane in Multiple Tumor Models.
-
Genetically Encoding Albumin Binding into Chemotherapeutic-loaded Polypeptide Nanoparticles Enhances Their Antitumor Efficacy.
-
Genetically Engineered Nanoparticles of Asymmetric Triblock Polypeptide with a Platinum(IV) Cargo Outperforms a Platinum(II) Analog and Free Drug in a Murine Cancer Model.
-
Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity.
-
Genetically manipulating endogenous Kras levels and oncogenic mutations in vivo influences tissue patterning of murine tumorigenesis.
-
Genetically stable poliovirus vectors activate dendritic cells and prime antitumor CD8 T cell immunity.
-
Genetics of parkin-linked disease.
-
Genetics. Origin of species in overdrive.
-
Genome Engineering of Stem Cells for Autonomously Regulated, Closed-Loop Delivery of Biologic Drugs.
-
Genome accessibility is widely preserved and locally modulated during mitosis.
-
Genome engineering: the next genomic revolution.
-
Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition.
-
Genome variation in Cryptococcus gattii, an emerging pathogen of immunocompetent hosts.
-
Genome wide analyses reveal little evidence for adaptive evolution in many plant species.
-
Genome-scale mutational signatures of aflatoxin in cells, mice, and human tumors.
-
Genome-wide CRISPR Screen to Identify Genes that Suppress Transformation in the Presence of Endogenous KrasG12D.
-
Genome-wide activity-dependent MeCP2 phosphorylation regulates nervous system development and function.
-
Genome-wide analysis of heat stress-stimulated transposon mobility in the human fungal pathogen Cryptococcus deneoformans.
-
Genome-wide analysis of miRNA signature in the APPswe/PS1ΔE9 mouse model of alzheimer's disease.
-
Genome-wide architecture of reproductive isolation in a naturally occurring hybrid zone between Mus musculus musculus and M. m. domesticus.
-
Genome-wide association of pericardial fat identifies a unique locus for ectopic fat.
-
Genome-wide association reveals contribution of MRAS to painful temporomandibular disorder in males.
-
Genome-wide association study identifies ZFHX1B as a susceptibility locus for severe myopia.
-
Genome-wide identification of autosomal genes with allelic imbalance of chromatin state.
-
Genome-wide identification of calcium-response factor (CaRF) binding sites predicts a role in regulation of neuronal signaling pathways.
-
Genome-wide identification of regulatory elements in Sertoli cells.
-
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.
-
Genome-wide mutational signatures of aristolochic acid and its application as a screening tool.
-
Genome-wide prediction of imprinted murine genes.
-
Genomic FHIT analysis in RER+ and RER- adenocarcinomas of the pancreas.
-
Genomic Status of MET Potentiates Sensitivity to MET and MEK Inhibition in NF1-Related Malignant Peripheral Nerve Sheath Tumors.
-
Genomic Variation across a Clinical Cryptococcus Population Linked to Disease Outcome.
-
Genomic abnormalities of the murine model of Fabry disease after disease-related perturbation, a systems biology approach.
-
Genomic acquisition of a capsular polysaccharide virulence cluster by non-pathogenic Burkholderia isolates.
-
Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene.
-
Genomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes.
-
Genomic dissection of conserved transcriptional regulation in intestinal epithelial cells.
-
Genomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns.
-
Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing glaucoma.
-
Genomic organization and cloning of the human homologue of murine Sipa-1.
-
Genomic organization of adrenergic and serotonin receptors in the mouse: linkage mapping of sequence-related genes provides a method for examining mammalian chromosome evolution.
-
Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.
-
Genomic size of CENP-A domain is proportional to total alpha satellite array size at human centromeres and expands in cancer cells.
-
Genomic structure and chromosomal localization of the novel ETS factor, PE-2 (ERF).
-
Genomically informed small-molecule drugs overcome resistance to a sustained-release formulation of an engineered death receptor agonist in patient-derived tumor models.
-
Genotypic analysis of B cell colonies by in situ hybridization. Stoichiometric expression of three VH families in adult C57BL/6 and BALB/c mice.
-
Genotypic and Phenotypic Diversity among Human Isolates of Akkermansia muciniphila.
-
Geometric calibration for a dual tube/detector micro-CT system.
-
Geometrical differences among homologous neurons in mammals.
-
Germ cells are not required to establish the female pathway in mouse fetal gonads.
-
Germinal Center Hypoxia Potentiates Immunoglobulin Class Switch Recombination.
-
Germinal center formation, immunoglobulin class switching, and autoantibody production driven by "non alpha/beta" T cells.
-
Germline AGO2 mutations impair RNA interference and human neurological development.
-
Germline Genetic IKZF1 Variation and Predisposition to Childhood Acute Lymphoblastic Leukemia.
-
Germline mutations in glial cell line-derived neurotrophic factor (GDNF) and RET in a Hirschsprung disease patient.
-
Germline sequences of V(H)7183 gene family members in C57BL/6 mice demonstrate natural selection of particular sequences during recent evolution.
-
Germline transcription from T-cell receptor Vbeta gene is uncoupled from allelic exclusion.
-
Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions.
-
Gestational Stage and IFN-λ Signaling Regulate ZIKV Infection In Utero.
-
Gestational, pathologic and biochemical differences between very long-chain acyl-CoA dehydrogenase deficiency and long-chain acyl-CoA dehydrogenase deficiency in the mouse.
-
Getting biological about the genetics of diabetes.
-
Ghrelin enhances olfactory sensitivity and exploratory sniffing in rodents and humans.
-
Gi alpha 1-mediated cardiac electrophysiological remodeling and arrhythmia in hypertrophic cardiomyopathy.
-
Gi-biased β2AR signaling links GRK2 upregulation to heart failure.
-
Giant ankyrin-G stabilizes somatodendritic GABAergic synapses through opposing endocytosis of GABAA receptors.
-
Giant ankyrin-G: a critical innovation in vertebrate evolution of fast and integrated neuronal signaling.
-
Giardia hinders growth by disrupting nutrient metabolism independent of inflammatory enteropathy.
-
Gipr is essential for adrenocortical steroidogenesis; however, corticosterone deficiency does not mediate the favorable metabolic phenotype of Gipr(-/-) mice.
-
Gli Transcription Factors Mediate the Oncogenic Transformation of Prostate Basal Cells Induced by a Kras-Androgen Receptor Axis.
-
Gli2 and p53 cooperate to regulate IGFBP-3- mediated chondrocyte apoptosis in the progression from benign to malignant cartilage tumors.
-
Glial ankyrins facilitate paranodal axoglial junction assembly.
-
Glial localization of antiquitin: implications for pyridoxine-dependent epilepsy.
-
Glioblastoma cell populations with distinct oncogenic programs release podoplanin as procoagulant extracellular vesicles.
-
Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth.
-
Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2.
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response.
-
Glipizide stimulates sympathetic outflow in diabetes-prone mice.
-
Global Identification of EVI1 Target Genes in Acute Myeloid Leukemia.
-
Global Motion Processing by Populations of Direction-Selective Retinal Ganglion Cells.
-
Global analysis of gene expression in renal ischemia-reperfusion in the mouse.
-
Global analysis of microRNA target gene expression reveals that miRNA targets are lower expressed in mature mouse and Drosophila tissues than in the embryos.
-
Global gene expression profiling reveals similarities and differences among mouse pluripotent stem cells of different origins and strains.
-
Global impact of RNA splicing on transcriptome remodeling in the heart.
-
Globin attenuates the innate immune response to endotoxin.
-
Glomerular type 1 angiotensin receptors augment kidney injury and inflammation in murine autoimmune nephritis.
-
Glucagon lowers glycemia when β-cells are active.
-
Glucagon-like peptide 2 for intestinal stem cell and Paneth cell repair during graft-versus-host disease in mice and humans.
-
Glucagon-like peptide-1 receptor agonists increase pancreatic mass by induction of protein synthesis.
-
Glucocorticoid receptor triggers a reversible drug-tolerant dormancy state with acquired therapeutic vulnerabilities in lung cancer.
-
Glucocorticoid treatment alleviates dystrophic myofiber pathology by activation of the calcineurin/NF-AT pathway.
-
Glucocorticoids and histone deacetylase inhibitors cooperate to block the invasiveness of basal-like breast cancer cells through novel mechanisms.
-
Glucose Activates Vagal Control of Hyperglycemia and Inflammation in Fasted Mice.
-
Glucose Metabolism in Cancer: The Saga of Pyruvate Kinase Continues.
-
Glucose activates mitogen-activated protein kinase (extracellular signal-regulated kinase) through proline-rich tyrosine kinase-2 and the Glut1 glucose transporter.
-
Glucose metabolism attenuates p53 and Puma-dependent cell death upon growth factor deprivation.
-
Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways.
-
Glucose-6-phosphatase mutation G188R confers an atypical glycogen storage disease type 1b phenotype.
-
Glucose-regulated protein 94/glycoprotein 96 elicits bystander activation of CD4+ T cell Th1 cytokine production in vivo.
-
Glutamate acting at NMDA receptors stimulates embryonic cortical neuronal migration.
-
Glutamatergic neuronal differentiation of mouse embryonic stem cells after transient expression of neurogenin 1 and treatment with BDNF and GDNF: in vitro and in vivo studies.
-
Glutaminase 2 negatively regulates the PI3K/AKT signaling and shows tumor suppression activity in human hepatocellular carcinoma.
-
Glutamine Metabolism Regulates Proliferation and Lineage Allocation in Skeletal Stem Cells.
-
Glutamine attenuates inflammation and NF-kappaB activation via Cullin-1 deneddylation.
-
Glutamine attenuation of cell death and inducible nitric oxide synthase expression following inflammatory cytokine-induced injury is dependent on heat shock factor-1 expression.
-
Glutamine enhances heat shock protein 70 expression via increased hexosamine biosynthetic pathway activity.
-
Glutamine in acute lung injury: the experimental model matters.
-
Glutamine induces heat shock protein expression via O-glycosylation and phosphorylation of HSF-1 and Sp1.
-
Glutamine therapy improves outcome of in vitro and in vivo experimental colitis models.
-
Glutamine's protection against cellular injury is dependent on heat shock factor-1.
-
Glutamine's protection against sepsis and lung injury is dependent on heat shock protein 70 expression.
-
Glutamine-mediated attenuation of cellular metabolic dysfunction and cell death after injury is dependent on heat shock factor-1 expression.
-
Glutamine-mediated dual regulation of heat shock transcription factor-1 activation and expression.
-
Glutathione and glutathione S-transferase in benign and malignant prostate cell lines and prostate tissues.
-
Glutathione depletion or radiation treatment alters respiration and induces apoptosis in R3230Ac mammary carcinoma.
-
Glutathione peroxidase-3 deficiency promotes platelet-dependent thrombosis in vivo.
-
Glutathione peroxidase-deficient smooth muscle cells cause paracrine activation of normal smooth muscle cells via cyclophilin A.
-
Glutathione protects cardiac and skeletal muscle from cyclophosphamide-induced toxicity.
-
Glutathione-associated cis-diamminedichloroplatinum(II) metabolism and ATP-dependent efflux from leukemia cells. Molecular characterization of glutathione-platinum complex and its biological significance.
-
Glycan binding avidity determines the systemic fate of adeno-associated virus type 9.
-
Glycated AAV vectors: chemical redirection of viral tissue tropism.
-
Glycerol phosphate shuttle enzyme GPD2 regulates macrophage inflammatory responses.
-
Glycerol-3-phosphate acyltransferase (GPAT)-1, but not GPAT4, incorporates newly synthesized fatty acids into triacylglycerol and diminishes fatty acid oxidation.
-
Glycogen accumulation in smooth muscle of a Pompe disease mouse model.
-
Glycogen storage in multiple muscles of old GSD-II mice can be rapidly cleared after a single intravenous injection with a modified adenoviral vector expressing hGAA.
-
Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1.
-
Glycogen synthase: a putative locus for diet-induced hyperglycemia.
-
Glycogen-branching enzyme deficiency leads to abnormal cardiac development: novel insights into glycogen storage disease IV.
-
Glycolipids and glycosyltransferases in permanent cell lines established from human medulloblastomas.
-
Glycolysis-dependent histone deacetylase 4 degradation regulates inflammatory cytokine production.
-
Glycopeptide epitope facilitates HIV-1 envelope specific humoral immune responses by eliciting T cell help.
-
Glycoprotein 96 perpetuates the persistent inflammation of rheumatoid arthritis.
-
Glymphatic fluid transport controls paravascular clearance of AAV vectors from the brain.
-
Glyphosate induces benign monoclonal gammopathy and promotes multiple myeloma progression in mice.
-
Gnao1 (G alphaO protein) is a likely genetic contributor to variation in physical dependence on opioids in mice.
-
Gnotobiotic models for study of the microbial ecology of Clostridium difficile and Escherichia coli.
-
Gold Nanostars: A Novel Platform for Developing 211At-Labeled Agents for Targeted Alpha-Particle Therapy.
-
Gold nanoparticles provide bright long-lasting vascular contrast for CT imaging.
-
Gold nanostars: surfactant-free synthesis, 3D modelling, and two-photon photoluminescence imaging.
-
Gonadotropin-releasing hormone neuronal cell lines.
-
Gp91phox contributes to NADPH oxidase activity in aortic fibroblasts but not smooth muscle cells.
-
Gq signaling causes glomerular injury by activating TRPC6.
-
Gq-dependent signaling upregulates COX2 in glomerular podocytes.
-
Gradated assembly of multiple proteins into supramolecular nanomaterials.
-
Graded diacylglycerol kinases α and ζ activities ensure mucosal-associated invariant T-cell development in mice.
-
Gradients of transgene expression directed by the human myoglobin promoter in the developing mouse heart.
-
Graft hyporeactivity induced by donor-derived dendritic cell progenitors.
-
Graft hyporeactivity induced by immature donor-derived dendritic cells.
-
Graft versus host disease following allogeneic bone marrow transplantation.
-
Graft-extrinsic cells predominate in vein graft arterialization.
-
Graft-versus-host disease prevention by rapamycin: cellular mechanisms.
-
Graft-versus-host disease: the viewpoint from the donor T cell.
-
Granulocyte chemotaxis and disease expression are differentially regulated by GRK subtype in an acute inflammatory arthritis model (K/BxN).
-
Granulocytes act as a niche for Mycobacterium tuberculosis growth.
-
Granulocytic MDSC with Deficient CCR5 Alleviates Lipogenesis and Inflammation in Nonalcoholic Fatty Liver Disease.
-
Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis.
-
Granzyme B is dispensable for immunologic tolerance to self in a murine model of systemic lupus erythematosus.
-
Graphene Enhances Actin Filament Assembly Kinetics and Modulates NIH-3T3 Fibroblast Cell Spreading.
-
Group VIA Ca2+-independent phospholipase A2 (iPLA2beta) and its role in beta-cell programmed cell death.
-
Group VIA Phospholipase A2 (iPLA2β) Modulates Bcl-x 5'-Splice Site Selection and Suppresses Anti-apoptotic Bcl-x(L) in β-Cells.
-
Growth and chemotherapeutic response in athymic mice of tumors arising from human glioma-derived cell lines.
-
Growth factor erv1-like modulates Drp1 to preserve mitochondrial dynamics and function in mouse embryonic stem cells.
-
Growth factor modulation of p53-mediated growth arrest versus apoptosis.
-
Growth factor receptor-bound protein 14 undergoes light-dependent intracellular translocation in rod photoreceptors: functional role in retinal insulin receptor activation.
-
Growth factor receptors as molecular targets for cancer diagnosis and therapy.
-
Growth factors can influence cell growth and survival through effects on glucose metabolism.
-
Growth factors regulate beta-catenin-mediated TCF-dependent transcriptional activation in fibroblasts during the proliferative phase of wound healing.
-
Growth failure and AIDS-like cachexia syndrome in HIV-1 transgenic mice.
-
Growth hormone accelerates immune recovery following allogeneic T-cell-depleted bone marrow transplantation in mice.
-
Growth hormone and prolactin receptors in adipogenesis: STAT-5 activation, suppressors of cytokine signaling, and regulation of insulin-like growth factor I.
-
Growth hormone mitigates against lethal irradiation and enhances hematologic and immune recovery in mice and nonhuman primates.
-
Growth hormone regulates phosphorylation and function of CCAAT/enhancer-binding protein beta by modulating Akt and glycogen synthase kinase-3.
-
Growth inhibition of a human lung adenocarcinoma cell line by genetic complementation with chromosome 11.
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Growth inhibition of pathogenic bacteria by sulfonylurea herbicides.
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Growth phenotypes and biosafety profiles in poliovirus-receptor transgenic mice of recombinant oncolytic polio/human rhinoviruses.
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Growth signaling at the nexus of stem cell life and death.
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Growth, morphology, and serial transplantation of anaplastic human gliomas in athymic mice.
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Growth-rate model predicts in vivo tumor resp