Hepatocyte Nuclear Factor 1

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  Subject Areas on Research

  • A complex intronic enhancer regulates expression of the CFTR gene by direct interaction with the promoter. 
  • Epigenetic determinants of ovarian clear cell carcinoma biology. 
  • Genomewide search for type 2 diabetes susceptibility genes in four American populations. 
  • Hepatocyte nuclear factor 1 alpha is expressed in a hamster insulinoma line and transactivates the rat insulin I gene. 
  • Identification of an ovarian clear cell carcinoma gene signature that reflects inherent disease biology and the carcinogenic processes. 
  • Intronic enhancers coordinate epithelial-specific looping of the active CFTR locus. 
  • The promoter for the gene encoding the catalytic subunit of rat glucose-6-phosphatase contains two distinct glucose-responsive regions.