Proto-Oncogene Proteins c-bcr
Subject Areas on Research
- A limited set of SH2 domains binds BCR through a high-affinity phosphotyrosine-independent interaction.
- Association of the protein kinases c-Bcr and Bcr-Abl with proteins of the 14-3-3 family.
- BAFF promotes heightened BCR responsiveness and manifestations of chronic GVHD after allogeneic stem cell transplantation.
- BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner.
- BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein.
- BCR-NTRK2 fusion in a low-grade glioma with distinctive morphology and unexpected aggressive behavior.
- CD19 regulates intrinsic B lymphocyte signal transduction and activation through a novel mechanism of processive amplification.
- Evidence for regulation of the human ABL tyrosine kinase by a cellular inhibitor.
- Lymphadenopathy, splenomegaly, and altered immunoglobulin production in BCL3 transgenic mice.
- Molecular and cytogenetic characterization of a novel translocation t(4;22) involving the breakpoint cluster region and platelet-derived growth factor receptor-alpha genes in a patient with atypical chronic myeloid leukemia.
- Role of the ABL oncogene tyrosine kinase activity in human leukaemia.
- The coiled-coil domain and Tyr177 of bcr are required to induce a murine chronic myelogenous leukemia-like disease by bcr/abl.
- Tyrosine kinase activity and transformation potency of bcr-abl oncogene products.