Subject Areas on Research
- B cell antigen receptor endocytosis and antigen presentation to T cells require Vav and dynamin.
- CD19 amplifies B lymphocyte signal transduction by regulating Src-family protein tyrosine kinase activation.
- CD19 and CD22 expression reciprocally regulates tyrosine phosphorylation of Vav protein during B lymphocyte signaling.
- CD19 regulates Src family protein tyrosine kinase activation in B lymphocytes through processive amplification.
- CD19 regulates innate immunity by the toll-like receptor RP105 signaling in B lymphocytes.
- CD28 costimulatory signal induces protein arginine methylation in T cells.
- Differential phosphorylation of functional tyrosines in CD19 modulates B-lymphocyte activation.
- Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line.
- Interferon-β therapy against EAE is effective only when development of the disease depends on the NLRP3 inflammasome.
- NKG2D-DAP10 triggers human NK cell-mediated killing via a Syk-independent regulatory pathway.
- NKG2D-mediated signaling requires a DAP10-bound Grb2-Vav1 intermediate and phosphatidylinositol-3-kinase in human natural killer cells.
- Nonobese diabetic congenic strain analysis of autoimmune diabetes reveals genetic complexity of the Idd18 locus and identifies Vav3 as a candidate gene.
- Vav Proteins Are Key Regulators of Card9 Signaling for Innate Antifungal Immunity.
- Vav and Rac activation in B cell antigen receptor endocytosis involves Vav recruitment to the adapter protein LAB.
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