KCNQ Potassium Channels

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  Subject Areas on Research

  • Antihistamine mepyramine directly inhibits KCNQ/M channel and depolarizes rat superior cervical ganglion neurons. 
  • BDNF profoundly and specifically increases KCNQ4 expression in neurons derived from embryonic stem cells. 
  • Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia. 
  • Inner ear abnormalities in a Kcnq1 (Kvlqt1) knockout mouse: a model of Jervell and Lange-Nielsen syndrome. 
  • NGF inhibits M/KCNQ currents and selectively alters neuronal excitability in subsets of sympathetic neurons depending on their M/KCNQ current background. 
  • Targeted disruption of the Kvlqt1 gene causes deafness and gastric hyperplasia in mice. 
  • [Bradykinin modulates ion channel in inflammatory pain].