Subject Areas on Research
- A common ankyrin-G-based mechanism retains KCNQ and NaV channels at electrically active domains of the axon.
- Autism and developmental disability caused by KCNQ3 gain-of-function variants.
- In vivo profile of ICA-27243 [N-(6-chloro-pyridin-3-yl)-3,4-difluoro-benzamide], a potent and selective KCNQ2/Q3 (Kv7.2/Kv7.3) activator in rodent anticonvulsant models.
- N-(6-chloro-pyridin-3-yl)-3,4-difluoro-benzamide (ICA-27243): a novel, selective KCNQ2/Q3 potassium channel activator.