Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
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Subject Areas on Research
- A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism.
- Antagonism between apolipoprotein AI regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein CIII gene expression in liver and intestinal cells.
- B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB.
- ChREBP regulates fructose-induced glucose production independently of insulin signaling.
- Clinical application of exome sequencing in undiagnosed genetic conditions.
- Common variants conferring risk of schizophrenia.
- Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1.
- Epstein-Barr virus induces global changes in cellular mRNA isoform usage that are important for the maintenance of latency.
- Expansion of CTG18.1 Trinucleotide Repeat in TCF4 Is a Potent Driver of Fuchs' Corneal Dystrophy.
- Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression.
- Identification and characterization of a highly conserved calcineurin binding protein, CBP1/calcipressin, in Cryptococcus neoformans.
- Induction of the ChREBPβ Isoform Is Essential for Glucose-Stimulated β-Cell Proliferation.
- Intestinal apolipoprotein AI gene transcription is regulated by multiple distinct DNA elements and is synergistically activated by the orphan nuclear receptor, hepatocyte nuclear factor 4.
- Isolation of two E-box binding factors that interact with the rat tyrosine hydroxylase enhancer.
- Lactic acidosis triggers starvation response with paradoxical induction of TXNIP through MondoA.
- Lysosomal basification and decreased autophagic flux in oxidatively stressed trabecular meshwork cells: implications for glaucoma pathogenesis.
- Mitochondrial polymorphism A10398G and Haplogroup I are associated with Fuchs' endothelial corneal dystrophy.
- Mutations in AGBL1 cause dominant late-onset Fuchs corneal dystrophy and alter protein-protein interaction with TCF4.
- Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy.
- Prevalence and severity of fuchs corneal dystrophy in Tangier Island.
- Replication of TCF4 through association and linkage studies in late-onset Fuchs endothelial corneal dystrophy.
- Replication of the TCF4 intronic variant in late-onset Fuchs corneal dystrophy and evidence of independence from the FCD2 locus.
- Sequence specificity incompletely defines the genome-wide occupancy of Myc.
- Serine/threonine phosphorylation regulates HNF-4alpha-dependent redox-mediated iNOS expression in hepatocytes.
- The impact of the metabotropic glutamate receptor and other gene family interaction networks on autism.
- Transcription factor E2-2 is an essential and specific regulator of plasmacytoid dendritic cell development.
- Type 2 diabetes: evidence for linkage on chromosome 20 in 716 Finnish affected sib pairs.
- Understanding pathologic variants of renal cell carcinoma: distilling therapeutic opportunities from biologic complexity.