Inhibitor of Differentiation Protein 1
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Subject Areas on Research
- Down-regulation of Bmp/Smad signaling by Tmprss6 is required for maintenance of systemic iron homeostasis.
- Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations.
- High incidence of T-cell tumors in E2A-null mice and E2A/Id1 double-knockout mice.
- Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts.
- LIF negatively regulates tumour-suppressor p53 through Stat3/ID1/MDM2 in colorectal cancers.
- Mammalian homologs of Drosophila ELAV localized to a neuronal subset can bind in vitro to the 3' UTR of mRNA encoding the Id transcriptional repressor.
- Mesenchymal high-grade glioma is maintained by the ID-RAP1 axis.
- Orchestration of invariant natural killer T cell development by E and Id proteins.
- Paradoxical role of Id proteins in regulating tumorigenic potential of lymphoid cells.
- Progesterone stimulates mitochondrial activity with subsequent inhibition of apoptosis in MCF-10A benign breast epithelial cells.
- Stromal heparan sulfate differentiates neuroblasts to suppress neuroblastoma growth.
- Targeting Id1 and Id3 inhibits peritoneal metastasis of gastric cancer.
- Type III TGF-β receptor promotes FGF2-mediated neuronal differentiation in neuroblastoma.
- Vascular endothelial growth factor impairs the functional ability of dendritic cells through Id pathways.