Smad Proteins, Receptor-Regulated

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  Subject Areas on Research

  • Axonally translated SMADs link up BDNF and retrograde BMP signaling. 
  • Micro-RNA 21 inhibition of SMAD7 enhances fibrogenesis via leptin-mediated NADPH oxidase in experimental and human nonalcoholic steatohepatitis. 
  • Notch signaling indirectly promotes chondrocyte hypertrophy via regulation of BMP signaling and cell cycle arrest. 
  • SMAD signaling drives heart and muscle dysfunction in a Drosophila model of muscular dystrophy.