Smad7 Protein

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  Subject Areas on Research

  • Deficient Smad7 expression: a putative molecular defect in scleroderma. 
  • Micro-RNA 21 inhibition of SMAD7 enhances fibrogenesis via leptin-mediated NADPH oxidase in experimental and human nonalcoholic steatohepatitis. 
  • TLR agonists regulate PDGF-B production and cell proliferation through TGF-beta/type I IFN crosstalk. 
  • Transforming growth factor beta3 regulates the versican variants in the extracellular matrix-rich uterine leiomyomas. 
  • miR-1269 promotes metastasis and forms a positive feedback loop with TGF-β.