Basigin

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  Subject Areas on Research

  • Abnormal creatine transport of mutations in monocarboxylate transporter 12 (MCT12) found in patients with age-related cataract can be partially rescued by exogenous chaperone CD147. 
  • Angiotensin II-induced MMP-2 activity and MMP-14 and basigin protein expression are mediated via the angiotensin II receptor type 1-mitogen-activated protein kinase 1 pathway in retinal pigment epithelium: implications for age-related macular degeneration. 
  • Proteomics characterization of cell membrane blebs in human retinal pigment epithelium cells. 
  • Thrombin-cleaved COOH(-) terminal osteopontin peptide binds with cyclophilin C to CD147 in murine breast cancer cells. 
  • Treatment of steroid-refractory acute graft-versus-host disease with anti-CD147 monoclonal antibody ABX-CBL. 
  • Trio-based exome sequencing arrests de novo mutations in early-onset high myopia. 
  • Tumor metabolism of lactate: the influence and therapeutic potential for MCT and CD147 regulation. 
  • Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms.