ELAV Proteins
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Subject Areas on Research
- A 50-year-old woman with bilateral vocal cord paralysis and hilar mass.
- ATM regulates a DNA damage response posttranscriptional RNA operon in lymphocytes.
- Activity-dependent expression of ELAV/Hu RBPs and neuronal mRNAs in seizure and cocaine brain.
- Activity-dependent expression of RNA binding protein HuD and its association with mRNAs in neurons.
- Association between the neuron-specific RNA-binding protein ELAVL4 and Parkinson disease.
- Caspase-mediated cleavage of HuR in the cytoplasm contributes to pp32/PHAP-I regulation of apoptosis.
- Conditional knockout of the RNA-binding protein HuR in CD4⁺ T cells reveals a gene dosage effect on cytokine production.
- Control of thymic T cell maturation, deletion and egress by the RNA-binding protein HuR.
- Coordinated posttranscriptional mRNA population dynamics during T-cell activation.
- ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation.
- ELAV proteins stabilize deadenylated intermediates in a novel in vitro mRNA deadenylation/degradation system.
- ELAV tumor antigen, Hel-N1, increases translation of neurofilament M mRNA and induces formation of neurites in human teratocarcinoma cells.
- Ectopic expression of Hel-N1, an RNA-binding protein, increases glucose transporter (GLUT1) expression in 3T3-L1 adipocytes.
- Embryonic lethal abnormal visual RNA-binding proteins involved in growth, differentiation, and posttranscriptional gene expression.
- Hel-N1, an RNA-binding protein, is a ligand for an A + U rich region of the GLUT1 3' UTR.
- Hel-N1: an autoimmune RNA-binding protein with specificity for 3' uridylate-rich untranslated regions of growth factor mRNAs.
- Identification of specific protein-RNA target sites using libraries of natural sequences.
- Identifying mRNA subsets in messenger ribonucleoprotein complexes by using cDNA arrays.
- Integrative regulatory mapping indicates that the RNA-binding protein HuR couples pre-mRNA processing and mRNA stability.
- Mammalian homologs of Drosophila ELAV localized to a neuronal subset can bind in vitro to the 3' UTR of mRNA encoding the Id transcriptional repressor.
- Mechanisms coordinating ELAV/Hu mRNA regulons.
- Messenger ribonucleoprotein complexes containing human ELAV proteins: interactions with cytoskeleton and translational apparatus.
- Neuron-specific ELAV/Hu proteins suppress HuR mRNA during neuronal differentiation by alternative polyadenylation.
- Paraneoplastic gaze palsies in a patient with negative anti-Hu and anti-Yo antibody tests.
- Post-transcriptional gene regulation by HuR promotes a more tumorigenic phenotype.
- RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation.
- Selection of a subset of mRNAs from combinatorial 3' untranslated region libraries using neuronal RNA-binding protein Hel-N1.
- Why is Hu where? Shuttling of early-response-gene messenger RNA subsets.