Transcription Factor RelA

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  Subject Areas on Research

  • Antibiotic-induced changes in the microbiota disrupt redox dynamics in the gut. 
  • Cardiomyocyte Maturation Requires TLR3 Activated Nuclear Factor Kappa B. 
  • Characterization of COMMD protein-protein interactions in NF-kappaB signalling. 
  • Characterization of short range DNA looping in endotoxin-mediated transcription of the murine inducible nitric-oxide synthase (iNOS) gene. 
  • Dimerization of NF-KB2 with RelA(p65) regulates DNA binding, transcriptional activation, and inhibition by an I kappa B-alpha (MAD-3). 
  • Dishevelled-3 activates p65 to upregulate p120-catenin transcription via a p38-dependent pathway in non-small cell lung cancer. 
  • Engineered zinc finger-activating vascular endothelial growth factor transcription factor plasmid DNA induces therapeutic angiogenesis in rabbits with hindlimb ischemia. 
  • Gα-13 induces CXC motif chemokine ligand 5 expression in prostate cancer cells by transactivating NF-κB. 
  • IL-1R signaling promotes STAT3 and NF-κB factor recruitment to distal cis-regulatory elements that regulate Il17a/f transcription. 
  • IRF-1 inhibits NF-κB activity, suppresses TRAF2 and cIAP1 and induces breast cancer cell specific growth inhibition. 
  • In vitro and in vivo molecular evidence of genistein action in augmenting the efficacy of cisplatin in pancreatic cancer. 
  • Interleukin-1beta mediates human airway epithelial cell migration via NF-kappaB. 
  • Interleukin-9 mediates chronic kidney disease-dependent vein graft disease: a role for mast cells. 
  • Modular utilization of distal cis-regulatory elements controls Ifng gene expression in T cells activated by distinct stimuli. 
  • NF-kappaB RelA opposes epidermal proliferation driven by TNFR1 and JNK. 
  • NF-kappaB p65 involves in reperfusion injury and iNOS gene regulation in skeletal muscle. 
  • NF-κB- and AP-1-mediated DNA looping regulates osteopontin transcription in endotoxin-stimulated murine macrophages. 
  • NOS2 regulation of LPS-induced airway inflammation via S-nitrosylation of NF-{kappa}B p65. 
  • NOS2 regulation of NF-kappaB by S-nitrosylation of p65. 
  • Natural IgM Switches the Function of Lipopolysaccharide-Activated Murine Bone Marrow-Derived Dendritic Cells to a Regulatory Dendritic Cell That Suppresses Innate Inflammation. 
  • Nuclear factor kappa B mediates lipopolysaccharide-induced inflammation in the urinary bladder. 
  • Overexpression of urokinase-type plasminogen activator in pancreatic adenocarcinoma is regulated by constitutively activated RelA. 
  • Perivascular mesenchymal cells control adipose-tissue macrophage accrual in obesity. 
  • Porcine endothelial cells cocultured with smooth muscle cells became procoagulant in vitro. 
  • Prolonged neuroinflammation after lipopolysaccharide exposure in aged rats. 
  • RelA NF-κB subunit activation as a therapeutic target in diffuse large B-cell lymphoma. 
  • Resistance to ErbB2 tyrosine kinase inhibitors in breast cancer is mediated by calcium-dependent activation of RelA. 
  • Response and resistance to NF-κB inhibitors in mouse models of lung adenocarcinoma. 
  • Signals from dying hepatocytes trigger growth of liver progenitors. 
  • Stabilization of p53 is a novel mechanism for proapoptotic function of NF-kappaB. 
  • Suppression of NF-kappaB-dependent proinflammatory gene expression in human RPE cells by a proteasome inhibitor. 
  • The effect of pro-inflammatory cytokines on the discharge rate of vagal nerve paraganglia in the rat. 
  • The nuclear factor-kappa B RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells. 
  • The role of p65 NF-kappaB/RelA in pancreatitis-induced Kupffer cell apoptosis. 
  • Thioredoxin-mediated denitrosylation regulates cytokine-induced nuclear factor κB (NF-κB) activation. 
  • Transcription of the RelB gene is regulated by NF-kappaB.