Adiponectin

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  Subject Areas on Research

  • A genome-wide association study reveals a quantitative trait locus of adiponectin on CDH13 that predicts cardiometabolic outcomes. 
  • A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2. 
  • Acute loss of adipose tissue-derived adiponectin triggers immediate metabolic deterioration in mice. 
  • Adiponectin and prostate cancer mortality: to be or not to be skinny? 
  • Adiponectin changes in relation to the macronutrient composition of a weight-loss diet. 
  • Adiponectin is essential for lipid homeostasis and survival under insulin deficiency and promotes β-cell regeneration. 
  • Adiponectin is not altered with exercise training despite enhanced insulin action. 
  • Adiponectin preserves metabolic fitness during aging. 
  • Adiponectin: an accurate biomarker for patients at risk for atrial fibrillation? 
  • Altered distribution of adiponectin isoforms in children with Prader-Willi syndrome (PWS): association with insulin sensitivity and circulating satiety peptide hormones. 
  • An Empirical Dietary Inflammatory Pattern Score Is Associated with Circulating Inflammatory Biomarkers in a Multi-Ethnic Population of Postmenopausal Women in the United States. 
  • Branched-chain α-keto acids and glutamate/glutamine: Biomarkers of insulin resistance in childhood obesity. 
  • Cardiometabolic Health in Submariners Returning from a 3-Month Patrol. 
  • Circulating des-acyl ghrelin improves cardiovascular risk prediction in older hypertensive patients. 
  • Dietary ω-3 polyunsaturated fatty acids decrease retinal neovascularization by adipose-endoplasmic reticulum stress reduction to increase adiponectin. 
  • Differential impacts of adiponectin on low-grade albuminuria between obese and nonobese persons without diabetes. 
  • Dysregulation of the microvasculature in nonlesional non-sun-exposed skin of patients with lupus nephritis. 
  • Effects of HIV infection on the metabolic and hormonal status of children with severe acute malnutrition. 
  • Effects of lactogen resistance and GH deficiency on mouse metabolism: pancreatic hormones, adipocytokines, and expression of adiponectin and insulin receptors. 
  • Elevated serum leptin, adiponectin and leptin to adiponectin ratio is associated with chronic kidney disease in Asian adults. 
  • Fat hormones pull their weight in the CNS. 
  • Gender differences in the relationships among obesity, adiponectin and brachial artery distensibility in adolescents and young adults. 
  • Genetic determinants of adiponectin regulation revealed by pregnancy. 
  • Genetic variation in adiponectin (ADIPOQ) and the type 1 receptor (ADIPOR1), obesity and prostate cancer in African Americans. 
  • Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. 
  • Genetic variations of the ADIPOQgene and risk of prostate cancer in Chinese Han men. 
  • Ghrelin concentrations in Prader-Willi syndrome (PWS) infants and children: changes during development. 
  • Host and environmental factors affect pulmonary responses measured in bronchoalveolar lavage. 
  • IGF-Binding Proteins, Adiponectin, and Survival in Metastatic Colorectal Cancer: Results From CALGB (Alliance)/SWOG 80405. 
  • Impact of statin therapy on plasma adiponectin concentrations: A systematic review and meta-analysis of 43 randomized controlled trial arms. 
  • Induction of osteoarthritis and metabolic inflammation by a very high-fat diet in mice: effects of short-term exercise. 
  • Influence of exercise intensity on abdominal fat and adiponectin in elderly adults. 
  • Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis. 
  • Insulin resistance is associated with a metabolic profile of altered protein metabolism in Chinese and Asian-Indian men. 
  • Is omega-3 key to unlocking inflammation in obesity? 
  • Metabolic profiling in Prader-Willi syndrome and nonsyndromic obesity: sex differences and the role of growth hormone. 
  • Neonatal exposure to parathion alters lipid metabolism in adulthood: Interactions with dietary fat intake and implications for neurodevelopmental deficits. 
  • Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. 
  • Obesity and primary graft dysfunction after lung transplantation: the Lung Transplant Outcomes Group Obesity Study. 
  • Omental gene expression of adiponectin correlates with degree of insulin sensitivity before and after gastric bypass surgery. 
  • Physiologic concentrations of exogenously infused ghrelin reduces insulin secretion without affecting insulin sensitivity in healthy humans. 
  • Physiological and Metabolic Changes During the Transition from Hyperthyroidism to Euthyroidism in Graves' Disease. 
  • Plasma des-acyl ghrelin, but not plasma HMW adiponectin, is a useful cardiometabolic marker for predicting atherosclerosis in elderly hypertensive patients. 
  • Pro- and antiatherogenic effects of a dominant-negative P465L mutation of peroxisome proliferator-activated receptor-γ in apolipoprotein E-Null mice. 
  • Response of adipose tissue to early infection with Trypanosoma cruzi (Brazil strain). 
  • Serum leptin levels are inversely correlated with omental gene expression of adiponectin and markedly decreased after gastric bypass surgery. 
  • Sex differences in biomarkers associated with insulin resistance in obese adolescents: metabolomic profiling and principal components analysis. 
  • The HMG-CoA reductase inhibitor pravastatin stimulates insulin secretion through organic anion transporter polypeptides. 
  • The STEDMAN project: biophysical, biochemical and metabolic effects of a behavioral weight loss intervention during weight loss, maintenance, and regain. 
  • The influence of abdominal visceral fat on inflammatory pathways and mortality risk in obstructive lung disease. 
  • Visceral fat and adiponectin: associations with insulin resistance are tissue-specific in women. 
  • Zfp423 Maintains White Adipocyte Identity through Suppression of the Beige Cell Thermogenic Gene Program. 
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  Keywords of People

  • Freemark, Michael Scott, Robert C. Atkins, M.D. and Veronica Atkins Distinguished Professor of Pediatrics, in the School of Medicine, Pediatrics, Endocrinology
  • Grambow, Steven C., Associate Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics