Influenza A Virus, H3N2 Subtype

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  Subject Areas on Research

  • A crowdsourced analysis to identify ab initio molecular signatures predictive of susceptibility to viral infection. 
  • A host transcriptional signature for presymptomatic detection of infection in humans exposed to influenza H1N1 or H3N2. 
  • A host-based RT-PCR gene expression signature to identify acute respiratory viral infection. 
  • A shortened interval between vaccinations with the trivalent inactivated influenza vaccine increases responsiveness in the aged. 
  • An individualized predictor of health and disease using paired reference and target samples. 
  • Comparison of the immunogenicity and safety of a split-virion, inactivated, trivalent influenza vaccine (Fluzone®) administered by intradermal and intramuscular route in healthy adults. 
  • Deep Sequencing of Influenza A Virus from a Human Challenge Study Reveals a Selective Bottleneck and Only Limited Intrahost Genetic Diversification. 
  • Detection of viruses via statistical gene expression analysis. 
  • Development and preclinical evaluation of an alphavirus replicon vaccine for influenza. 
  • Differential evolution of peripheral cytokine levels in symptomatic and asymptomatic responses to experimental influenza virus challenge. 
  • Differential pulmonary transcriptomic profiles in murine lungs infected with low and highly virulent influenza H3N2 viruses reveal dysregulation of TREM1 signaling, cytokines, and chemokines. 
  • Editorial commentary: variant Influenza A(H3N2) virus: looking through a glass, darkly. 
  • Evidence for Cross-species Influenza A Virus Transmission Within Swine Farms, China: A One Health, Prospective Cohort Study. 
  • Evidence for antigenic seniority in influenza A (H3N2) antibody responses in southern China. 
  • Gene Expression Profiles Link Respiratory Viral Infection, Platelet Response to Aspirin, and Acute Myocardial Infarction. 
  • Genetic evolution of the neuraminidase of influenza A (H3N2) viruses from 1968 to 2009 and its correspondence to haemagglutinin evolution. 
  • H3N2 influenza infection elicits more cross-reactive and less clonally expanded anti-hemagglutinin antibodies than influenza vaccination. 
  • Identification of microRNAs in Throat Swab as the Biomarkers for Diagnosis of Influenza. 
  • Immunization with trivalent inactivated influenza vaccine in partially immunized toddlers. 
  • Immunogenicity, safety and consistency of new trivalent inactivated influenza vaccine. 
  • Influenza vaccination during the first 6 months after solid organ transplantation is efficacious and safe. 
  • Influenza vaccine immunogenicity in 6- to 23-month-old children: are identical antigens necessary for priming? 
  • Longitudinal analysis of leukocyte differentials in peripheral blood of patients with acute respiratory viral infections. 
  • Molecular detection of a novel human influenza (H1N1) of pandemic potential by conventional and real-time quantitative RT-PCR assays. 
  • Nasopharyngeal Protein Biomarkers of Acute Respiratory Virus Infection. 
  • Novel role of gastrin releasing peptide-mediated signaling in the host response to influenza infection. 
  • Pattern recognition molecule mindin promotes intranasal clearance of influenza viruses. 
  • Phylodynamic inference and model assessment with approximate bayesian computation: influenza as a case study. 
  • Poor Immunogenicity, Not Vaccine Strain Egg Adaptation, May Explain the Low H3N2 Influenza Vaccine Effectiveness in 2012-2013. 
  • Prevention and control of seasonal influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices (ACIP) -- United States, 2014-15 influenza season. 
  • Prospective surveillance for influenza. virus in Chinese swine farms. 
  • Serological Evidence and Risk Factors for Swine Influenza Infections among Chinese Swine Workers in Guangdong Province. 
  • Temporal dynamics of host molecular responses differentiate symptomatic and asymptomatic influenza a infection. 
  • Temporally structured metapopulation dynamics and persistence of influenza A H3N2 virus in humans. 
  • The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. 
  • The effects of a deleterious mutation load on patterns of influenza A/H3N2's antigenic evolution in humans. 
  • The impact of host immune status on the within-host and population dynamics of antigenic immune escape. 
  • Transmissibility of pandemic H1N1 and genetically related swine influenza viruses in ferrets. 
  • Two Doses of Inactivated Influenza Vaccine Improve Immune Response in Solid Organ Transplant Recipients: Results of TRANSGRIPE 1-2, a Randomized Controlled Clinical Trial. 
  • Understanding the dynamics of rapidly evolving pathogens through modeling the tempo of antigenic change: influenza as a case study. 
  • Unsupervised Bayesian linear unmixing of gene expression microarrays. 
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  Keywords of People

  • McClain, Micah Thomas, Associate Professor of Medicine, Medicine, Infectious Diseases