TNF-Related Apoptosis-Inducing Ligand
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Subject Areas on Research
- A double hit to kill tumor and endothelial cells by TRAIL and antiangiogenic 3TSR.
- Blazing a new TRAIL in hematopoietic cell transplantation.
- Gene expression patterns that characterize advanced stage serous ovarian cancers.
- Hepatocyte growth factor enhances death receptor-induced apoptosis by up-regulating DR5.
- High expression of tumor necrosis factor-related apoptosis-inducing ligand is associated with favorable ovarian cancer survival.
- Impaired TRAIL-dependent cytotoxicity of CD1c-positive dendritic cells in chronic hepatitis C virus infection.
- In vitro sensitivity testing of minimally passaged and uncultured gliomas with TRAIL and/or chemotherapy drugs.
- Induction of plasma (TRAIL), TNFR-2, Fas ligand, and plasma microparticles after human immunodeficiency virus type 1 (HIV-1) transmission: implications for HIV-1 vaccine design.
- Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II.
- Interferon regulatory factor-1-induced apoptosis mediated by a ligand-independent fas-associated death domain pathway in breast cancer cells.
- Lipopolysaccharide-induced expression of TRAIL promotes dendritic cell differentiation.
- Nuclear factor-kappaB maintains TRAIL resistance in human pancreatic cancer cells.
- On the TRAIL from p53 to apoptosis?
- Poxvirus tumor necrosis factor receptor (TNFR)-like T2 proteins contain a conserved preligand assembly domain that inhibits cellular TNFR1-induced cell death.
- Preligand assembly domain-mediated ligand-independent association between TRAIL receptor 4 (TR4) and TR2 regulates TRAIL-induced apoptosis.
- Radiation-inducible caspase-8 gene therapy for malignant brain tumors.
- Radioresponsive tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) gene therapy for malignant brain tumors.
- Redox-Active Mn Porphyrin-based Potent SOD Mimic, MnTnBuOE-2-PyP(5+), Enhances Carbenoxolone-Mediated TRAIL-Induced Apoptosis in Glioblastoma Multiforme.
- Risk of ovarian cancer and the NF-κB pathway: genetic association with IL1A and TNFSF10.
- Smac mimetic Birinapant induces apoptosis and enhances TRAIL potency in inflammatory breast cancer cells in an IAP-dependent and TNF-α-independent mechanism.
- The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease.
- Three-in-one chromatography-free purification, tag removal, and site-specific modification of recombinant fusion proteins using sortase A and elastin-like polypeptides.
- X-linked inhibitor of apoptosis protein inhibition induces apoptosis and enhances chemotherapy sensitivity in human prostate cancer cells.
- XIAP inhibition and generation of reactive oxygen species enhances TRAIL sensitivity in inflammatory breast cancer cells.
- c-FLIP maintains tissue homeostasis by preventing apoptosis and programmed necrosis.
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Keywords of People
- Berchuck, Andrew, James M. Ingram Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
- Weinhold, Kent James, Joseph W. and Dorothy W. Beard Professor of Experimental Surgery, in the School of Medicine, Immunology