Tumor Necrosis Factor Ligand Superfamily Member 13
Subject Areas on Research
- BAFF expression correlates with idiopathic inflammatory myopathy disease activity measures and autoantibodies.
- BAFF is increased in renal transplant patients following treatment with alemtuzumab.
- BLyS and APRIL in rheumatoid arthritis.
- DNA vaccine molecular adjuvants SP-D-BAFF and SP-D-APRIL enhance anti-gp120 immune response and increase HIV-1 neutralizing antibody titers.
- Neutralizing BAFF/APRIL with atacicept prevents early DSA formation and AMR development in T cell depletion induced nonhuman primate AMR model.
- Targeting HIV-1 envelope glycoprotein trimers to B cells by using APRIL improves antibody responses.