Caspase 10

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  Subject Areas on Research

  • Association between CASP8 and CASP10 polymorphisms and toxicity outcomes with platinum-based chemotherapy in Chinese patients with non-small cell lung cancer. 
  • Caspase 8 is absent or low in many ex vivo gliomas. 
  • Genetic variants and haplotypes of the caspase-8 and caspase-10 genes contribute to susceptibility to cutaneous melanoma. 
  • Identification of high caspase-3 mRNA expression as a unique signature profile for extremely old individuals. 
  • Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II.