Interleukin-1alpha
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Subject Areas on Research
- A functional variant at miRNA-122 binding site in IL-1a 3' UTR predicts risk of recurrence in patients with oropharyngeal cancer.
- A functional variant at miRNA-122 binding site in IL-1α 3' UTR predicts risk and HPV-positive tumours of oropharyngeal cancer.
- Absence of posttraumatic arthritis following intraarticular fracture in the MRL/MpJ mouse.
- An Enrichment Strategy For Sepsis Clinical Trials.
- CXCL10 is upregulated in synovium and cartilage following articular fracture.
- Effective induction of protective systemic immunity with nasally administered vaccines adjuvanted with IL-1.
- Genetic and cellular evidence of decreased inflammation associated with reduced incidence of posttraumatic arthritis in MRL/MpJ mice.
- Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.
- Immunocompetent murine model of cancer cachexia for head and neck squamous cell carcinoma.
- Inflammatory signaling sensitizes Piezo1 mechanotransduction in articular chondrocytes as a pathogenic feed-forward mechanism in osteoarthritis.
- Influence of oxygen tension on interleukin 1-induced peroxynitrite formation and matrix turnover in articular cartilage.
- Maximal adjuvant activity of nasally delivered IL-1α requires adjuvant-responsive CD11c(+) cells and does not correlate with adjuvant-induced in vivo cytokine production.
- Modulation of Human Macrophage Responses to Mycobacterium tuberculosis by Silver Nanoparticles of Different Size and Surface Modification.
- Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production.
- Ovarian cancer risk associated with inherited inflammation-related variants.
- Reactive nitrogen and oxygen species in interleukin-1-mediated DNA damage associated with osteoarthritis.
- Risk of ovarian cancer and the NF-κB pathway: genetic association with IL1A and TNFSF10.
- Stimulation of hair follicle stem cell proliferation through an IL-1 dependent activation of γδT-cells.
- Synovial fluid concentrations and relative potency of interleukin-1 alpha and beta in cartilage and meniscus degradation.
- The pediatric sepsis biomarker risk model: potential implications for sepsis therapy and biology.
- Virus binding to a plasma membrane receptor triggers interleukin-1 alpha-mediated proinflammatory macrophage response in vivo.
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Keywords of People
- Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
- Gunn, Michael Dee, Professor of Medicine, Integrative Immunobiology