Interleukin 1 Receptor Antagonist Protein
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Subject Areas on Research
- A case report of mevalonate kinase deficiency in a 14-month-old female with fevers and lower extremity weakness.
- A deficit in astroglial organization causes the impaired reactive sprouting in human apolipoprotein E4 targeted replacement mice.
- Acute Intervention With Selective Interleukin-1 Inhibitor Therapy May Reduce the Progression of Posttraumatic Osteoarthritis of the Knee: A Systematic Review of Current Evidence.
- Anakinra as first-line disease-modifying therapy in systemic juvenile idiopathic arthritis: report of forty-six patients from an international multicenter series.
- Anatomically shaped tissue-engineered cartilage with tunable and inducible anticytokine delivery for biological joint resurfacing.
- Apolipoprotein E genotype differentially influences the proinflammatory and anti-inflammatory response to cardiopulmonary bypass.
- Association of maternal IL-1 receptor antagonist intron 2 gene polymorphism and preterm birth.
- Association study of two interleukin-1 gene loci with essential hypertension in a Pakistani Pathan population.
- Bladder fibrosis during outlet obstruction is triggered through the NLRP3 inflammasome and the production of IL-1β.
- Changes in serum and synovial fluid biomarkers after acute injury (NCT00332254).
- Clinical benefits of intra-articular anakinra for persistent knee effusion.
- Combination of Lidocaine and IL-1Ra Is Effective at Reducing Degradation of Porcine Cartilage Explants.
- Complementary Approaches for Military Women with Chronic Pelvic Pain: A Randomized Trial.
- Development and characterization of a fusion protein between thermally responsive elastin-like polypeptide and interleukin-1 receptor antagonist: sustained release of a local antiinflammatory therapeutic.
- Effect of Interleukin-1 Blockade on Left Ventricular Systolic Performance and Work: A Post Hoc Pooled Analysis of 2 Clinical Trials.
- Effect of an interleukin-1 receptor antagonist on the hemodynamic manifestations of group B streptococcal sepsis.
- Effects of intraarticular IL1-Ra for acute anterior cruciate ligament knee injury: a randomized controlled pilot trial (NCT00332254).
- Emerging ideas: prevention of posttraumatic arthritis through interleukin-1 and tumor necrosis factor-alpha inhibition.
- Enhanced integrative repair of the porcine meniscus in vitro by inhibition of interleukin-1 or tumor necrosis factor alpha.
- Excess risk of temporomandibular disorder associated with cigarette smoking in young adults.
- Expression of interleukin-1 and interleukin-1 receptor antagonists in endometrial cancer.
- Feasibility randomised multicentre, double-blind, double-dummy controlled trial of anakinra, an interleukin-1 receptor antagonist versus intramuscular methylprednisolone for acute gout attacks in patients with chronic kidney disease (ASGARD): protocol study.
- Gait and behavior in an IL1β-mediated model of rat knee arthritis and effects of an IL1 antagonist.
- Genome-wide association study of circulating interleukin 6 levels identifies novel loci.
- Inducible nitric oxide synthase promotes cytokine expression in cardiac allografts but is not required for efficient rejection.
- Induction of osteoarthritis and metabolic inflammation by a very high-fat diet in mice: effects of short-term exercise.
- Inflammatory Markers and Incidence of Hospitalization With Infection in Chronic Kidney Disease.
- Interleukin 1 receptor antagonist (IL1RN) gene variants predict radiographic severity of knee osteoarthritis and risk of incident disease.
- Interleukin-1 Blockade in Recently Decompensated Systolic Heart Failure: Results From REDHART (Recently Decompensated Heart Failure Anakinra Response Trial).
- Interleukin-1 receptor antagonist anakinra in association with remdesivir in severe COVID-19: A case report.
- Medical management of acute gout.
- Multisystem Inflammatory Syndrome in Children: Survey of Protocols for Early Hospital Evaluation and Management.
- Necrotizing Sweet Syndrome of the Upper Extremity After Elective Hand Surgery.
- Pilot study comparing the Childhood Arthritis & Rheumatology Research Alliance (CARRA) systemic Juvenile Idiopathic Arthritis Consensus Treatment Plans.
- Plasma cytokines associated with febrile status epilepticus in children: A potential biomarker for acute hippocampal injury.
- Protease-degradable PEG-maleimide coating with on-demand release of IL-1Ra to improve tissue response to neural electrodes.
- RNA-guided gene activation by CRISPR-Cas9-based transcription factors.
- Radiographic severity of knee osteoarthritis is conditional on interleukin 1 receptor antagonist gene variations.
- Reverse Translation in Advancing Pharmacotherapy in Pediatric Rheumatology: A Logical Approach in Rare Diseases with Limited Resources.
- Role of interleukin-1beta in postoperative cognitive dysfunction.
- Severity of Plasma Leakage Is Associated With High Levels of Interferon γ-Inducible Protein 10, Hepatocyte Growth Factor, Matrix Metalloproteinase 2 (MMP-2), and MMP-9 During Dengue Virus Infection.
- Sustained intra-articular delivery of IL-1RA from a thermally-responsive elastin-like polypeptide as a therapy for post-traumatic arthritis.
- Systemic lupus erythematosus and genetic variation in the interleukin 1 gene cluster: a population based study in the southeastern United States.
- Targeting pro-inflammatory cytokines following joint injury: acute intra-articular inhibition of interleukin-1 following knee injury prevents post-traumatic arthritis.
- The effect of covalently immobilized rhIL-1ra-ELP fusion protein on the inflammatory profile of LPS-stimulated human monocytes.
- The first reported case of compound heterozygous IL1RN mutations causing deficiency of the interleukin-1 receptor antagonist.
- The induction of matrix metalloproteinase and cytokine expression in synovial fibroblasts stimulated with immune cell microparticles.
- The upregulation of specific interleukin (IL) receptor antagonists and paradoxical enhancement of neuronal apoptosis due to electrode induced strain and brain micromotion.
- Therapeutic opportunities to prevent post-traumatic arthritis: Lessons from the natural history of arthritis after articular fracture.
- Tides of inflammation: impact of biologics.
- Tissue-engineered cartilage with inducible and tunable immunomodulatory properties.
- Usefulness of Interleukin-1 Receptor Antagonists in Patients With Recurrent Pericarditis.
- Utilization patterns and characteristics of users of biologic anti-inflammatory agents in a large, US commercially insured population.
- cDNA cloning of an intracellular form of the human interleukin 1 receptor antagonist associated with epithelium.
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Keywords of People
- Reddy, Timothy E, Associate Professor of Biostatistics & Bioinformatics,, Molecular Genetics and Microbiology