Embryonic Stem Cells
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Subject Areas on Research
- A conversation with Oliver Smithies.
- A shared vision.
- A tiling-deletion-based genetic screen for cis-regulatory element identification in mammalian cells.
- An avian model for the reversal of neurobehavioral teratogenicity with neural stem cells.
- BDNF profoundly and specifically increases KCNQ4 expression in neurons derived from embryonic stem cells.
- Bimodal quantitative relationships between histone modifications for X-linked and autosomal loci.
- Biomaterials directed in vivo osteogenic differentiation of mesenchymal cells derived from human embryonic stem cells.
- Brominated and organophosphate flame retardants target different neurodevelopmental stages, characterized with embryonic neural stem cells and neuronotypic PC12 cells.
- CHD7 targets active gene enhancer elements to modulate ES cell-specific gene expression.
- Cartilage tissue engineering: Directed differentiation of embryonic stem cells in three-dimensional hydrogel culture.
- Chondrogenic differentiation of human embryonic germ cell derived cells in hydrogels.
- Chromatin architecture reorganization during stem cell differentiation.
- Combining topographical and genetic cues to promote neuronal fate specification in stem cells.
- Comparison of reprogramming efficiency between transduction of reprogramming factors, cell-cell fusion, and cytoplast fusion.
- Controlled differentiation of stem cells.
- Derivation of chondrogenically-committed cells from human embryonic cells for cartilage tissue regeneration.
- Developmental neurotoxicity resulting from pharmacotherapy of preterm labor, modeled in vitro: Terbutaline and dexamethasone, separately and together.
- Directed differentiation and neurite extension of mouse embryonic stem cell on aligned poly(lactide) nanofibers functionalized with YIGSR peptide.
- Distinct DNA methylation patterns characterize differentiated human embryonic stem cells and developing human fetal liver.
- Diverse neurotoxicants target the differentiation of embryonic neural stem cells into neuronal and glial phenotypes.
- Enhanced chondrogenic differentiation of embryonic stem cells by coculture with hepatic cells.
- Enhanced therapeutic neovascularization by CD31-expressing cells and embryonic stem cell-derived endothelial cells engineered with chitosan hydrogel containing VEGF-releasing microtubes.
- Epigenomic comparison reveals activation of "seed" enhancers during transition from naive to primed pluripotency.
- Epithelial progenitor cells of the embryonic lung and the role of microRNAs in their proliferation.
- Essential and unexpected role of Yin Yang 1 to promote mesodermal cardiac differentiation.
- Expression of Neurogenin 1 in mouse embryonic stem cells directs the differentiation of neuronal precursors and identifies unique patterns of down-stream gene expression.
- Genome-wide chromatin state transitions associated with developmental and environmental cues.
- Genomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns.
- Germline transcription from T-cell receptor Vbeta gene is uncoupled from allelic exclusion.
- Global gene expression profiling reveals similarities and differences among mouse pluripotent stem cells of different origins and strains.
- Glutamatergic neuronal differentiation of mouse embryonic stem cells after transient expression of neurogenin 1 and treatment with BDNF and GDNF: in vitro and in vivo studies.
- Growth factor erv1-like modulates Drp1 to preserve mitochondrial dynamics and function in mouse embryonic stem cells.
- Heme Oxygenase-1/Carbon Monoxide System and Embryonic Stem Cell Differentiation and Maturation into Cardiomyocytes.
- High-content imaging-based screening of microenvironment-induced changes to stem cells.
- Human neural progenitors express functional lysophospholipid receptors that regulate cell growth and morphology.
- Human pluripotent stem cell-derived neural constructs for predicting neural toxicity.
- Identification of a novel epigenetic regulatory region within the pluripotency associated microRNA cluster, EEmiRC.
- Implantation of mouse embryonic stem cell-derived cardiac progenitor cells preserves function of infarcted murine hearts.
- In vitro models reveal differences in the developmental neurotoxicity of an environmental polycylic aromatic hydrocarbon mixture compared to benzo[a]pyrene: Neuronotypic PC12 Cells and embryonic neural stem cells.
- In vivo commitment and functional tissue regeneration using human embryonic stem cell-derived mesenchymal cells.
- In vivo comparison of biomineralized scaffold-directed osteogenic differentiation of human embryonic and mesenchymal stem cells.
- Induced pluripotent stem cell-derived cardiac progenitors differentiate to cardiomyocytes and form biosynthetic tissues.
- Influence of threonine metabolism on S-adenosylmethionine and histone methylation.
- Intraspinal transplantation of neurogenin-expressing stem cells generates spinal cord neural progenitors.
- Lattice light-sheet microscopy: imaging molecules to embryos at high spatiotemporal resolution.
- Long-term human pluripotent stem cell self-renewal on synthetic polymer surfaces.
- Mammalian genes induce partially reprogrammed pluripotent stem cells in non-mammalian vertebrate and invertebrate species.
- Manipulation of OCT4 levels in human embryonic stem cells results in induction of differential cell types.
- Minireview: Nuclear receptors, hematopoiesis, and stem cells.
- Netrin-1-mediated axon guidance in mouse embryonic stem cells overexpressing neurogenin-1.
- Overlapping and opposing functions of G protein-coupled receptor kinase 2 (GRK2) and GRK5 during heart development.
- Reprogramming after chromosome transfer into mouse blastomeres.
- SFRP2 regulates cardiomyogenic differentiation by inhibiting a positive transcriptional autofeedback loop of Wnt3a.
- Specification of chondrocytes and cartilage tissues from embryonic stem cells.
- Stem Cell Surface Marker Expression Defines Late Stages of Reprogramming to Pluripotency in Human Fibroblasts.
- Summary: present and future challenges for stem cell research.
- TBX3 Directs Cell-Fate Decision toward Mesendoderm.
- The Id2+ distal tip lung epithelium contains individual multipotent embryonic progenitor cells.
- The cell surface glycosphingolipids SSEA-3 and SSEA-4 are not essential for human ESC pluripotency.
- The generation and characterization of novel Col1a1FRT-Cre-ER-T2-FRT and Col1a1FRT-STOP-FRT-Cre-ER-T2 mice for sequential mutagenesis.
- The secreted metalloprotease ADAMTS20 is required for melanoblast survival.
- Therapy with Cardiomyocytes Derived from Pluripotent Cells in Chronic Chagasic Cardiomyopathy.
- Tissue-engineered cardiac patch for advanced functional maturation of human ESC-derived cardiomyocytes.
- Toward a blueprint for regeneration.
- Viable Mice with Extensive Gene Humanization (25-kbp) Created Using Embryonic Stem Cell/Blastocyst and CRISPR/Zygote Injection Approaches.
- WNT3 is a biomarker capable of predicting the definitive endoderm differentiation potential of hESCs.
- WNT3A promotes myogenesis of human embryonic stem cells and enhances in vivo engraftment.
- piggyBac as a high-capacity transgenesis and gene-therapy vector in human cells and mice.
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Keywords of People
- Velkey, John Matthew, Assistant Professor of the Practice of Medical Education in the Department of Cell Biology, Cell Biology