Interleukin-12 Subunit p40

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  Subject Areas on Research

  • A promoter polymorphism in the gene encoding interleukin-12 p40 (IL12B) is associated with mortality from cerebral malaria and with reduced nitric oxide production. 
  • Anti-phosphorylcholine-opsonized low-density lipoprotein promotes rapid production of proinflammatory cytokines by dendritic cells and natural killer cells. 
  • Association of Common Genetic Polymorphisms with Melanoma Patient IL-12p40 Blood Levels, Risk, and Outcomes. 
  • Engineering B cells with mRNA. 
  • IL-10 and class 1 histone deacetylases act synergistically and independently on the secretion of proinflammatory mediators in alveolar macrophages. 
  • IL-10 regulates Il12b expression via histone deacetylation: implications for intestinal macrophage homeostasis. 
  • Interactions of IL-12A and IL-12B polymorphisms on the risk of cervical cancer in Chinese women. 
  • Interleukin 12B (IL12B) genetic variation and pulmonary tuberculosis: a study of cohorts from The Gambia, Guinea-Bissau, United States and Argentina. 
  • MCP1 SNPs and pulmonary tuberculosis in cohorts from West Africa, the USA and Argentina: lack of association or epistasis with IL12B polymorphisms. 
  • NFIL3-deficient mice develop microbiota-dependent, IL-12/23-driven spontaneous colitis. 
  • Platelets deliver costimulatory signals to antigen-presenting cells: a potential bridge between injury and immune activation. 
  • The linker for activation of B cells (LAB)/non-T cell activation linker (NTAL) regulates triggering receptor expressed on myeloid cells (TREM)-2 signaling and macrophage inflammatory responses independently of the linker for activation of T cells. 
  • The modulation of dendritic cell integrin binding and activation by RGD-peptide density gradient substrates. 
  • The relationship between blood IL-12p40 level and melanoma progression.