DNA Fragmentation
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Subject Areas on Research
- A primary role for K+ and Na+ efflux in the activation of apoptosis.
- A unique role of the DNA fragmentation factor in maintaining genomic stability.
- Activation of the de novo biosynthesis of sphingolipids mediates angiotensin II type 2 receptor-induced apoptosis.
- Adenovirus-mediated wild-type p53 tumor suppressor gene therapy induces apoptosis and suppresses growth of human pancreatic cancer [seecomments].
- Angiotensin II type 2 receptor mediates vascular smooth muscle cell apoptosis and antagonizes angiotensin II type 1 receptor action: an in vitro gene transfer study.
- Angiotensin type 2 receptor dephosphorylates Bcl-2 by activating mitogen-activated protein kinase phosphatase-1 and induces apoptosis.
- Antisense to transforming growth factor-beta(1) facilitates the apoptosis of macrophages in rat vein grafts.
- Apoptosis and delayed neuronal damage after carbon monoxide poisoning in the rat.
- Apoptosis in human retinal degenerations.
- Apoptosis rate can be accelerated or decelerated by overexpression or reduction of the level of elongation factor-1 alpha.
- Apoptotic DNA fragmentation factor maintains chromosome stability in a P53-independent manner.
- Apoptotic nuclease assays.
- Bayesian latent variable models for median regression on multiple outcomes.
- Benzodiazepines protect hippocampal neurons from degeneration after transient cerebral ischemia: an ultrastructural study.
- Calpain mediates ischemic injury of the liver through modulation of apoptosis and necrosis.
- Caspase-8-mediated apoptosis in human RPE cells.
- Correlation of DNA fragmentation and chromatin condensation in apoptotic nuclei of the Ser 6 mouse retina.
- Delayed myocardial preconditioning by alpha1-adrenoceptors involves inhibition of apoptosis.
- Dietary isothiocyanate-induced apoptosis via thiol modification of DNA topoisomerase IIα.
- Effects of the proteasome inhibitor PS-341 on apoptosis and angiogenesis in orthotopic human pancreatic tumor xenografts.
- Endogenous expression of transforming growth factor beta1 inhibits growth and tumorigenicity and enhances Fas-mediated apoptosis in a murine high-grade glioma model.
- Endothelial cell and hepatocyte deaths occur by apoptosis after ischemia-reperfusion injury in the rat liver.
- Enhanced H(2)O(2)-induced cytotoxicity in "epithelioid" smooth muscle cells: implications for neointimal regression.
- Evidence that non-caspase proteases are required for chromatin degradation during apoptosis.
- Glucocorticoid-induced thymocyte apoptosis: protease-dependent activation of cell shrinkage and DNA degradation.
- Hippocampal programmed cell death after status epilepticus: evidence for NMDA-receptor and ceramide-mediated mechanisms.
- Increased skin carcinogenesis in caspase-activated DNase knockout mice.
- Induction of apoptosis by the novel retinoid AHPN in human T-cell lymphoma cells involves caspase-dependent and independent pathways.
- Induction of apoptotic cell death by particulate lead chromate: differential effects of vitamins C and E on genotoxicity and survival.
- Interferon regulatory factors regulate interleukin-1beta-converting enzyme expression and apoptosis in vascular smooth muscle cells.
- Intracellular K+ suppresses the activation of apoptosis in lymphocytes.
- JCPyV T-Antigen Activation of the Anti-Apoptotic Survivin Promoter-Its Role in the Development of Progressive Multifocal Leukoencephalopathy.
- Labeling Single Domain Antibody Fragments with Fluorine-18 Using 2,3,5,6-Tetrafluorophenyl 6-[18F]Fluoronicotinate Resulting in High Tumor-to-Kidney Ratios.
- Modulation of cytokine-induced cardiac myocyte apoptosis by nitric oxide, Bak, and Bcl-x.
- NMDA-induced apoptosis in mixed neuronal/glial cortical cell cultures: the effects of isoflurane and dizocilpine.
- Native recombinant cyclophilins A, B, and C degrade DNA independently of peptidylprolyl cis-trans-isomerase activity. Potential roles of cyclophilins in apoptosis.
- Next-generation sequencing of apoptotic DNA breakpoints reveals association with actively transcribed genes and gene translocations.
- Oxidant-induced cell death in retinal pigment epithelium cells mediated through the release of apoptosis-inducing factor.
- Oxidative stress mediates monocrotaline-induced alterations in tenascin expression in pulmonary artery endothelial cells.
- Peptide elongation factor eEF1A-2/S1 expression in cultured differentiated myotubes and its protective effect against caspase-3-mediated apoptosis.
- Postlipopolysaccharide oxidative damage of mitochondrial DNA.
- Pregnancy after varicocelectomy: impact of postoperative motility and DFI.
- Proliferation and apoptosis of fibroblasts and smooth muscle cells in rat uterine cervix throughout gestation and the effect of the antiprogesterone onapristone.
- Protein kinase C-zeta is critical in pancreatitis-induced apoptosis of Kupffer cells.
- Re: Pregnancy after varicocelectomy: impact of postoperative motility and DFI.
- Redefining the relationship between sperm deoxyribonucleic acid fragmentation as measured by the sperm chromatin structure assay and outcomes of assisted reproductive techniques.
- Regulation of apoptosis in Xenopus egg extracts.
- Regulation of apoptosis resistance and ontogeny of age-dependent diseases.
- Regulation of mammalian horizontal gene transfer by apoptotic DNA fragmentation.
- Regulation of tumor necrosis factor cytotoxicity by calcineurin.
- Resveratrol prevents protein nitration and release of endonucleases from mitochondria during acetaminophen hepatotoxicity.
- Solution structure of DFF40 and DFF45 N-terminal domain complex and mutual chaperone activity of DFF40 and DFF45.
- Solution structure of the CIDE-N domain of CIDE-B and a model for CIDE-N/CIDE-N interactions in the DNA fragmentation pathway of apoptosis.
- Tepoxalin enhances the activity of an antioxidant, pyrrolidine dithiocarbamate, in attenuating tumor necrosis factor alpha-induced apoptosis in WEHI 164 cells.
- The content of DNA and RNA in microparticles released by Jurkat and HL-60 cells undergoing in vitro apoptosis.
- The role of p65 NF-kappaB/RelA in pancreatitis-induced Kupffer cell apoptosis.
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Keywords of People
- Schwartz-Bloom, Rochelle D., Professor Emeritus of Pharmacology & Cancer Biology, Duke Science & Society