Pentacyclic Triterpenes
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Subject Areas on Research
- Activation and inhibition of the proteasome by betulinic acid and its derivatives.
- Anti-AIDS agents 49. Synthesis, anti-HIV, and anti-fusion activities of IC9564 analogues based on betulinic acid.
- Anti-AIDS agents 81. Design, synthesis, and structure-activity relationship study of betulinic acid and moronic acid derivatives as potent HIV maturation inhibitors.
- Anti-AIDS agents--XXVII. Synthesis and anti-HIV activity of betulinic acid and dihydrobetulinic acid derivatives.
- Anti-AIDS agents. 78. Design, synthesis, metabolic stability assessment, and antiviral evaluation of novel betulinic acid derivatives as potent anti-human immunodeficiency virus (HIV) agents.
- Betulinic acid and dihydrobetulinic acid derivatives as potent anti-HIV agents.
- Betulinic acid derivatives as HIV-1 antivirals.
- Betulinic acid derivatives as human immunodeficiency virus type 2 (HIV-2) inhibitors.
- Betulinic acid derivatives that target gp120 and inhibit multiple genetic subtypes of human immunodeficiency virus type 1.
- Bifunctional anti-human immunodeficiency virus type 1 small molecules with two novel mechanisms of action.
- Conjugates of betulin derivatives with AZT as potent anti-HIV agents.
- Diterpenoid, steroid, and triterpenoid agonists of liver X receptors from diversified terrestrial plants and marine sources.
- Fluorinated betulinic acid derivatives and evaluation of their anti-HIV activity.
- New betulinic acid derivatives as potent proteasome inhibitors.
- Role of human immunodeficiency virus (HIV) type 1 envelope in the anti-HIV activity of the betulinic acid derivative IC9564.
- Synthesis and anti-HIV activity of bi-functional betulinic acid derivatives.
- Synthesis of betulinic acid derivatives as entry inhibitors against HIV-1 and bevirimat-resistant HIV-1 variants.
- The discovery of a class of novel HIV-1 maturation inhibitors and their potential in the therapy of HIV.