Viral Regulatory and Accessory Proteins
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Subject Areas on Research
- A quantitative, high-throughput screen for protein stability.
- Backbone dynamics of the monomeric lambda repressor denatured state ensemble under nondenaturing conditions.
- Characterization of the trans-activation properties of equine herpesvirus 1 EICP0 protein.
- Contribution of a buried hydrogen bond to lambda repressor folding kinetics.
- Crystallization of a complex of cro repressor with a 17 base-pair operator.
- Folding kinetics of a fluorescent variant of monomeric lambda repressor.
- Functional analysis of the simian immunodeficiency virus Vpx protein: identification of packaging determinants and a novel nuclear targeting domain.
- Generalized dead-end elimination algorithms make large-scale protein side-chain structure prediction tractable: implications for protein design and structural genomics.
- Global re-wiring of p53 transcription regulation by the hepatitis B virus X protein.
- Heat and cold denatured states of monomeric lambda repressor are thermodynamically and conformationally equivalent.
- Hedgehog signaling blockade delays hepatocarcinogenesis induced by hepatitis B virus X protein.
- Identification of hepatitis B virus aetiologic antigens, HBx and Pre-S2, in diffuse large B-cell lymphoma.
- Interaction with cellular CD4 exposes HIV-1 envelope epitopes targeted by antibody-dependent cell-mediated cytotoxicity.
- Kinetic role of helix caps in protein folding is context-dependent.
- Lethal-7 is down-regulated by the hepatitis B virus x protein and targets signal transducer and activator of transcription 3.
- Methionine oxidation of monomeric lambda repressor: the denatured state ensemble under nondenaturing conditions.
- Microsecond protein folding through a compact transition state.
- Mutation of p53 gene in hepatocellular carcinoma cell lines with HBX DNA.
- Optimal sequence selection in proteins of known structure by simulated evolution.
- Postnatal pre- and postexposure passive immunization strategies: protection of neonatal macaques against oral simian-human immunodeficiency virus challenge.
- Probing the DNA sequence specificity of Escherichia coli RECA protein.
- Protein folding dynamics: quantitative comparison between theory and experiment.
- Protein-DNA conformational changes in the crystal structure of a lambda Cro-operator complex.
- Simian immunodeficiency virus-Vpx for improving integrase defective lentiviral vector-based vaccines.
- Structure and stability of monomeric lambda repressor: NMR evidence for two-state folding.
- Submillisecond folding of monomeric lambda repressor.
- The Expression of Functional Vpx during Pathogenic SIVmac Infections of Rhesus Macaques Suppresses SAMHD1 in CD4+ Memory T Cells.
- The energetic contribution of backbone--backbone hydrogen bonds to the thermodynamic stability of a hyperstable P22 Arc repressor mutant.
- The energy landscape of a fast-folding protein mapped by Ala-->Gly substitutions.
- The structural distribution of cooperative interactions in proteins: analysis of the native state ensemble.
- Thermodynamic stability measurements on multimeric proteins using a new H/D exchange- and matrix-assisted laser desorption/ionization (MALDI) mass spectrometry-based method.