Subject Areas on Research
- A role for fractalkine and its receptor (CX3CR1) in cardiac allograft rejection.
- CX3CR1 tyrosine sulfation enhances fractalkine-induced cell adhesion.
- CX3CR1-dependent renal macrophage survival promotes Candida control and host survival.
- Chemokines, neuronal-glial interactions, and central processing of neuropathic pain.
- Enrichment of endogenous fractalkine and anti-inflammatory cells via aptamer-functionalized hydrogels.
- Fractalkine and CX3CR1 mediate a novel mechanism of leukocyte capture, firm adhesion, and activation under physiologic flow.
- Immunoengineering nerve repair.
- Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy.
- Mitogen-activated protein kinase phosphatase-1 promotes neovascularization and angiogenic gene expression.
- Mutational analysis of the fractalkine chemokine domain. Basic amino acid residues differentially contribute to CX3CR1 binding, signaling, and cell adhesion.
- Role of the CX3CR1/p38 MAPK pathway in spinal microglia for the development of neuropathic pain following nerve injury-induced cleavage of fractalkine.
- The chemokine CX3CL1 regulates NK cell activity in vivo.
- The homozygous CX3CR1-M280 mutation impairs human monocyte survival.
- Ultrastructure and function of the fractalkine mucin domain in CX(3)C chemokine domain presentation.
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