Calcium-Calmodulin-Dependent Protein Kinase Type 4
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Subject Areas on Research
- A signaling complex of Ca2+-calmodulin-dependent protein kinase IV and protein phosphatase 2A.
- A unique phosphorylation-dependent mechanism for the activation of Ca2+/calmodulin-dependent protein kinase type IV/GR.
- Activation of orphan receptor-mediated transcription by Ca(2+)/calmodulin-dependent protein kinase IV.
- BDNF-mediated cerebellar granule cell development is impaired in mice null for CaMKK2 or CaMKIV.
- Biochemical characterization of the multifunctional Ca2+/calmodulin-dependent protein kinase type IV expressed in insect cells.
- Ca(2+)/calmodulin-dependent protein kinase IV is expressed in spermatids and targeted to chromatin and the nuclear matrix.
- Ca2+/calmodulin-dependent protein kinase IV and calcium signaling.
- Ca2+/calmodulin-dependent protein kinase type IV in dorsal root ganglion: colocalization with peptides, axonal transport and effect of axotomy.
- Calcium/calmodulin-dependent kinase IV in immune and inflammatory responses: novel routes for an ancient traveller.
- Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression.
- Calmodulin-dependent kinase IV links Toll-like receptor 4 signaling with survival pathway of activated dendritic cells.
- Calmodulin-dependent protein kinase IV regulates hematopoietic stem cell maintenance.
- Calmodulin-dependent protein kinase IV regulates nuclear export of Cabin1 during T-cell activation.
- Calspermin gene transcription is regulated by two cyclic AMP response elements contained in an alternative promoter in the calmodulin kinase IV gene.
- Catalytic activity is required for calcium/calmodulin-dependent protein kinase IV to enter the nucleus.
- Cerebellar defects in Ca2+/calmodulin kinase IV-deficient mice.
- Defective signaling in a subpopulation of CD4(+) T cells in the absence of Ca(2+)/calmodulin-dependent protein kinase IV.
- Defective survival and activation of thymocytes in transgenic mice expressing a catalytically inactive form of Ca2+/calmodulin-dependent protein kinase IV.
- Expression of Ca(2+)/calmodulin-dependent protein kinase IV (caMKIV) messenger RNA during murine embryogenesis.
- Generation of silent synapses by acute in vivo expression of CaMKIV and CREB.
- MEF2 responds to multiple calcium-regulated signals in the control of skeletal muscle fiber type.
- Methionine to glutamine substitutions in the C-terminal domain of calmodulin impair the activation of three protein kinases.
- Organization and analysis of the complete rat calmodulin-dependent protein kinase IV gene.
- Phosphorylation and activation of Ca(2+)-calmodulin-dependent protein kinase IV by Ca(2+)-calmodulin-dependent protein kinase Ia kinase. Phosphorylation of threonine 196 is essential for activation.
- Physiological roles of the Ca2+/CaM-dependent protein kinase cascade in health and disease.
- Pressure overload selectively up-regulates Ca2+/calmodulin-dependent protein kinase II in vivo.
- Proteomic analysis of calcium/calmodulin-dependent protein kinase I and IV in vitro substrates reveals distinct catalytic preferences.
- Regulation and function of the calcium/calmodulin-dependent protein kinase IV/protein serine/threonine phosphatase 2A signaling complex.
- Regulation of mitochondrial biogenesis in skeletal muscle by CaMK.
- Regulatory cascades involving calmodulin-dependent protein kinases.
- Requirement for Ca2+/calmodulin-dependent kinase type IV/Gr in setting the thymocyte selection threshold.
- Spermatogenesis and the regulation of Ca(2+)-calmodulin-dependent protein kinase IV localization are not dependent on calspermin.
- Spermiogenesis and exchange of basic nuclear proteins are impaired in male germ cells lacking Camk4.