Fatty Acid Synthase, Type I

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  Subject Areas on Research

  • A bioorthogonal chemical reporter for fatty acid synthase-dependent protein acylation. 
  • Activated α2-macroglobulin binding to human prostate cancer cells triggers insulin-like responses. 
  • Cellular fatty acid synthase is required for late stages of HIV-1 replication. 
  • De novo mutations in synaptic transmission genes including DNM1 cause epileptic encephalopathies. 
  • Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2(+) Breast Cancer.