Bone Morphogenetic Protein 2
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Subject Areas on Research
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A BMP pathway regulates cell fate allocation along the sea urchin animal-vegetal embryonic axis.
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A cost analysis of bone morphogenetic protein versus autogenous iliac crest bone graft in single-level anterior lumbar fusion.
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AMH induces mesonephric cell migration in XX gonads.
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Adam10 is essential for early embryonic cardiovascular development.
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An injectable method for noninvasive spine fusion.
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BMP receptor IA is required in mammalian neural crest cells for development of the cardiac outflow tract and ventricular myocardium.
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BMP-2 and BMP-9 promotes chondrogenic differentiation of human multipotential mesenchymal cells and overcomes the inhibitory effect of IL-1.
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BMP-2 and TGFβ2 shared pathways regulate endocardial cell transformation.
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BMP-2 inhibits tumor growth of human renal cell carcinoma and induces bone formation.
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BMP-2 inhibits tumor-initiating ability in human renal cancer stem cells and induces bone formation.
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BMP2, but not BMP4, is crucial for chondrocyte proliferation and maturation during endochondral bone development.
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BMPs induce dermal markers and ectopic feather tracts.
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Bone Morphogenetic Proteins Are Expressed by Both Bone-Forming and Non-Bone-Forming Lesions.
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Bone formation induced by BMP-2 in human osteosarcoma cells.
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Bone morphogenetic protein 2 opposes Shh-mediated proliferation in cerebellar granule cells through a TIEG-1-based regulation of Nmyc.
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Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression.
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Cartilage-specific β-catenin signaling regulates chondrocyte maturation, generation of ossification centers, and perichondrial bone formation during skeletal development.
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Cell-based gene therapy for repair of critical size defects in the rat fibula.
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Cellular and molecular responses of the uterus to embryo implantation can be elicited by locally applied growth factors.
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Characterization of the distinct orthotopic bone-forming activity of 14 BMPs using recombinant adenovirus-mediated gene delivery.
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Combined bone morphogenetic protein-2 and -7 gene transfer enhances osteoblastic differentiation and spine fusion in a rodent model.
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Concentration-Dependent hMSC Differentiation on Orthogonal Concentration Gradients of GRGDS and BMP-2 Peptides.
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Cost-Utility Analysis of rhBMP-2 Use in Adult Spinal Deformity Surgery.
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Deficiency of heme-regulated eIF2alpha kinase decreases hepcidin expression and splenic iron in HFE-/- mice.
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Degenerative lumbar scoliosis.
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Disease progression in iridocorneal angle tissues of BMP2-induced ocular hypertensive mice with optical coherence tomography.
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Does recombinant human bone morphogenetic protein-2 use in adult spinal deformity increase complications and are complications associated with location of rhBMP-2 use? A prospective, multicenter study of 279 consecutive patients.
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Editorial. Anterior cervical fusion and rhBMP-2: a prospective study is needed to assess optimal dosing and delivery.
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Editorial: Recombinant human bone morphogenetic protein-2.
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Encapsulation of Adenovirus BMP2-Transduced Cells with PEGDA Hydrogels Allows Bone Formation in the Presence of Immune Response.
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Endocardial cell epithelial-mesenchymal transformation requires Type III TGFβ receptor interaction with GIPC.
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Endochondral bone formation from hydrogel carriers loaded with BMP2-transduced cells.
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Endogenous bone morphogenetic protein antagonists regulate mammalian neural crest generation and survival.
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Engineered pluripotent mesenchymal cells integrate and differentiate in regenerating bone: a novel cell-mediated gene therapy.
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Enhanced osteogenic activity of poly(ester urea) scaffolds using facile post-3D printing peptide functionalization strategies.
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Epithelial Smad4 Deletion Up-Regulates Inflammation and Promotes Inflammation-Associated Cancer.
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Evidence that mouse Bmp8a (Op2) and Bmp8b are duplicated genes that play a role in spermatogenesis and placental development.
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Follistatin operates downstream of Wnt4 in mammalian ovary organogenesis.
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Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.
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Heterotopic ossification in rectal cancer: Rare finding with a novel proposed mechanism.
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Hydrogel microsphere encapsulation of a cell-based gene therapy system increases cell survival of injected cells, transgene expression, and bone volume in a model of heterotopic ossification.
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Iliac crest bone graft donor site pain after anterior lumbar interbody fusion: a prospective patient satisfaction outcome assessment.
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In vitro and in vivo osteoblastic differentiation of BMP-2- and Runx2-engineered skeletal myoblasts.
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Intradiscal injection of simvastatin results in radiologic, histologic, and genetic evidence of disc regeneration in a rat model of degenerative disc disease.
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LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development.
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Long-Segment Fusion for Adult Spinal Deformity Correction Using Low-Dose Recombinant Human Bone Morphogenetic Protein-2: A Retrospective Review of Fusion Rates.
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Mass Spectrometry and Ion Mobility Characterization of Bioactive Peptide-Synthetic Polymer Conjugates.
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Modification of Poly(propylene fumarate)-Bioglass Composites with Peptide Conjugates to Enhance Bioactivity.
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Msx Homeobox Genes Act Downstream of BMP2 to Regulate Endometrial Decidualization in Mice and in Humans.
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Neural plate morphogenesis during mouse neurulation is regulated by antagonism of Bmp signalling.
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Notch signaling indirectly promotes chondrocyte hypertrophy via regulation of BMP signaling and cell cycle arrest.
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Outcomes of Bone Grafting of Bone Cysts After Total Ankle Arthroplasty.
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Outcomes of bone morphogenetic protein-2 in mature adults: posterolateral non-instrument-assisted lumbar decompression and fusion.
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Predictors of Revision Surgical Procedure Excluding Wound Complications in Adult Spinal Deformity and Impact on Patient-Reported Outcomes and Satisfaction: A Two-Year Follow-up.
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RNA-binding protein FXR2 regulates adult hippocampal neurogenesis by reducing Noggin expression.
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Rapid healing of femoral defects in rats with low dose sustained BMP2 expression from PEGDA hydrogel microspheres.
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Recombinant human bone morphogenetic protein-2 as an adjunct for spine fusion in a pediatric population.
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Regeneration of fat cells from myofibroblasts during wound healing.
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Restriction of hepatic competence by Fgf signaling.
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Safety, efficacy, and dosing of recombinant human bone morphogenetic protein-2 for posterior cervical and cervicothoracic instrumented fusion with a minimum 2-year follow-up.
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Scaffold-based rhBMP-2 therapy in a rat alveolar defect model: implications for human gingivoperiosteoplasty.
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Skeletal abnormalities in doubly heterozygous Bmp4 and Bmp7 mice.
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Sulfated glycopeptide nanostructures for multipotent protein activation.
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Sustained release of BMP-2 in a lipid-based microtube vehicle.
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Synergistic enhancement of human bone marrow stromal cell proliferation and osteogenic differentiation on BMP-2-derived and RGD peptide concentration gradients.
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TAK1 regulates SOX9 expression in chondrocytes and is essential for postnatal development of the growth plate and articular cartilages.
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The BMP signaling pathway leads to enhanced proliferation in serous ovarian cancer-A potential therapeutic target.
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The forkhead/winged helix gene Mf1 is disrupted in the pleiotropic mouse mutation congenital hydrocephalus.
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The use of allograft and recombinant human bone morphogenetic protein for instrumented atlantoaxial fusions.
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Use of rhBMP-2 for adult spinal deformity surgery: patterns of usage and changes over the past decade.
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Valency-dependent affinity of bioactive hydroxyapatite-binding dendrons.
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Vascular tissues are a primary source of BMP2 expression during bone formation induced by distraction osteogenesis.
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WNT4 acts downstream of BMP2 and functions via β-catenin signaling pathway to regulate human endometrial stromal cell differentiation.
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[BMP-2 gene carried by biodegradable scaffold and fibrinous gel for repairing segmental radial defect in rabbit].
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p38α MAPK regulates proliferation and differentiation of osteoclast progenitors and bone remodeling in an aging-dependent manner.
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