Insulin Receptor Substrate Proteins
-
Subject Areas on Research
- Alzheimer’s disease: the new promise.
- Aspartyl-(asparaginyl)-beta-hydroxylase regulates hepatocellular carcinoma invasiveness.
- Biomedicine. Insulin resistance takes a trip through the ER.
- E2-induced degradation of uterine insulin receptor substrate-2: requirement for an IGF-I-stimulated, proteasome-dependent pathway.
- Endotoxin mediated-iNOS induction causes insulin resistance via ONOO⁻ induced tyrosine nitration of IRS-1 in skeletal muscle.
- Exercise maintains euglycemia in association with decreased activation of c-Jun NH2-terminal kinase and serine phosphorylation of IRS-1 in the liver of ZDF rats.
- Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile.
- Insulin receptor substrate is a mediator of phosphoinositide 3-kinase activation in quiescent pancreatic cancer cells.
- Insulin receptor substrate-1 (IRS-1) expression in rat brain.
- Insulin-like growth factor axis gene polymorphisms and clinical outcomes in pancreatic cancer.
- Knockout of TRPC6 promotes insulin resistance and exacerbates glomerular injury in Akita mice.
- Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.
- Mechanisms by which smoothelin-like protein 1 reverses insulin resistance in myotubules and mice.
- Potential role of PTEN phosphatase in ethanol-impaired survival signaling in the liver.
- Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.
- Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production.
- The MicroRNA miR-191 Supports T Cell Survival Following Common γ Chain Signaling.
- The proximity-labeling technique BioID identifies sorting nexin 6 as a member of the insulin-like growth factor 1 (IGF1)-IGF1 receptor pathway.
- beta-arrestin-1 competitively inhibits insulin-induced ubiquitination and degradation of insulin receptor substrate 1.