Ceramidases

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  Subject Areas on Research

  • Enzymes of ceramide biosynthesis. 
  • Fumonisin B1 inhibits sphingosine (sphinganine) N-acyltransferase and de novo sphingolipid biosynthesis in cultured neurons in situ. 
  • Fumonisin toxicity and sphingolipid biosynthesis. 
  • Fumonisins and other inhibitors of de novo sphingolipid biosynthesis. 
  • Induction of apoptotic cell death and prevention of tumor growth by ceramide analogues in metastatic human colon cancer. 
  • Sphingolipids--the enigmatic lipid class: biochemistry, physiology, and pathophysiology.