Mechanical Phenomena

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  Subject Areas on Research

  • A Comparison of Acoustic Radiation Force-Derived Indices of Cardiac Function in the Langendorff Perfused Rabbit Heart. 
  • A Hierarchical Nanoparticle-in-Micropore Architecture for Enhanced Mechanosensitivity and Stretchability in Mechanochromic Electronic Skins. 
  • A composite kidney stone phantom with mechanical properties controllable over the range of human kidney stones. 
  • A mathematical model of mechanotransduction reveals how mechanical memory regulates mesenchymal stem cell fate decisions. 
  • A novel method for measuring asymmetry in kinematic and kinetic variables: The normalized symmetry index. 
  • An estimate to the first approximation of microtubule rupture force. 
  • Bicyclo[3.2.0]heptane mechanophores for the non-scissile and photochemically reversible generation of reactive bis-enones. 
  • Bipedal and quadrupedal locomotion in chimpanzees. 
  • Capturing the mechanical unfolding pathway of a large protein with coiled-coil probes. 
  • Cessation of biomechanical stretch model of C2C12 cells models myocyte atrophy and anaplerotic changes in metabolism using non-targeted metabolomics analysis. 
  • Compounds from silicones alter enzyme activity in curing barnacle glue and model enzymes. 
  • Compressive Force With 2-Screw and 3-Screw Subtalar Joint Arthrodesis With Headless Compression Screws. 
  • Cone outer segments: a biophysical model of membrane dynamics, shape retention, and lamella formation. 
  • Direct observation of multimer stabilization in the mechanical unfolding pathway of a protein undergoing oligomerization. 
  • Dynamics of Forced Nucleosome Unraveling and Role of Nonuniform Histone-DNA Interactions 
  • Elastomeric polyamide biomaterials with stereochemically tuneable mechanical properties and shape memory. 
  • Examining the viability of carbon fiber reinforced three-dimensionally printed prosthetic feet created by composite filament fabrication. 
  • Highly-compliant, microcable neuroelectrodes fabricated from thin-film gold and PDMS. 
  • Influence of pulling handles and device stiffness in single-molecule force spectroscopy. 
  • Instrumentation of off-the-shelf ultrasound system for measurement of probe forces during freehand imaging. 
  • Localized force application reveals mechanically sensitive domains of Piezo1. 
  • Mechanical Properties of a Drosophila Larval Chordotonal Organ. 
  • Mechanical Stability of a Small, Highly-Luminescent Engineered Protein NanoLuc. 
  • Mechanical anisotropy of ankyrin repeats. 
  • Mechanical sensitivity of Piezo1 ion channels can be tuned by cellular membrane tension. 
  • Metallic Nanoislands on Graphene as Highly Sensitive Transducers of Mechanical, Biological, and Optical Signals. 
  • Mitral valvular interstitial cell responses to substrate stiffness depend on age and anatomic region. 
  • Modifying the mechanics of healing infarcts: Is better the enemy of good? 
  • Modular, Nondegenerate Polyprotein Scaffolds for Atomic Force Spectroscopy. 
  • Multi-Modal Haptic Feedback for Grip Force Reduction in Robotic Surgery. 
  • On the Quantitative Potential of Viscoelastic Response (VisR) Ultrasound Using the One-Dimensional Mass-Spring-Damper Model. 
  • On the relative importance of bending and compression in cervical spine bilateral facet dislocation. 
  • Optical Phase Measurements of Disorder Strength Link Microstructure to Cell Stiffness. 
  • Optical coherence tomography through a rigid borescope applied to quantification of articular cartilage thickness in a porcine knee model. 
  • Probe Sensitivity to Cortical versus Intracellular Cytoskeletal Network Stiffness. 
  • Protein unfolding under isometric tension-what force can integrins generate, and can it unfold FNIII domains? 
  • Relationship between T1rho magnetic resonance imaging, synovial fluid biomarkers, and the biochemical and biomechanical properties of cartilage. 
  • Remodeling Tissue Interfaces and the Thermodynamics of Zipping during Dorsal Closure in Drosophila. 
  • Resorbable, amino acid-based poly(ester urea)s crosslinked with osteogenic growth peptide with enhanced mechanical properties and bioactivity. 
  • Sacrificial bonds in stacked-cup carbon nanofibers: biomimetic toughening mechanisms for composite systems. 
  • Scaling and mechanics of carnivoran footpads reveal the principles of footpad design. 
  • Stiffness characterization of anisotropic trabecular meshwork. 
  • The biomechanics of concussive helmet-to-ground impacts in the National Football league. 
  • The direct incorporation of perfusion defect information to define ischemia and infarction in a finite element model of the left ventricle. 
  • The effect of aging on low-fat, reduced-fat, and full-fat Cheddar cheese texture. 
  • The impact of hepatic pressurization on liver shear wave speed estimates in constrained versus unconstrained conditions. 
  • The modulation of MSC integrin expression by RGD presentation. 
  • The synthesis and coating of long, thin copper nanowires to make flexible, transparent conducting films on plastic substrates. 
  • Triggering a cell shape change by exploiting preexisting actomyosin contractions. 
  • Tuning the mechanical properties of graphene oxide paper and its associated polymer nanocomposites by controlling cooperative intersheet hydrogen bonding. 
  • Unraveling the Mechanical Unfolding Pathways of a Multidomain Protein: Phosphoglycerate Kinase. 
  • Utilizing cell-matrix interactions to modulate gene transfer to stem cells inside hyaluronic acid hydrogels. 
  • Vinculin Force-Sensitive Dynamics at Focal Adhesions Enable Effective Directed Cell Migration. 
  • Warhammers for Peaceful Times. 
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  Keywords of People

  • Preminger, Glenn Michael, James F. Glenn, M.D. Distinguished Professor of Urology, Surgery
  • Zhong, Pei, Professor in the Department of Mechanical Engineering and Materials Science, Thomas Lord Department of Mechanical Engineering and Materials Science