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Subject Areas on Research
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Advances in the treatment of invasive neonatal candidiasis.
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Antifungal Extraction by the Extracorporeal Membrane Oxygenation Circuit.
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Antifungal resistance: the clinical front.
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Antifungal treatment in pediatric patients.
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Antillatoxin, a novel lipopeptide, enhances neurite outgrowth in immature cerebrocortical neurons through activation of voltage-gated sodium channels.
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Antillatoxin-Stimulated Neurite Outgrowth Involves the Brain-Derived Neurotrophic Factor (BDNF) - Tropomyosin Related Kinase B (TrkB) Signaling Pathway.
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Breakthrough invasive candidiasis in patients on micafungin.
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Calcineurin controls drug tolerance, hyphal growth, and virulence in Candida dubliniensis.
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Calcineurin controls hyphal growth, virulence, and drug tolerance of Candida tropicalis.
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Calcineurin inhibition or mutation enhances cell wall inhibitors against Aspergillus fumigatus.
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Calcineurin is required for pseudohyphal growth, virulence, and drug resistance in Candida lusitaniae.
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Calcineurin orchestrates dimorphic transitions, antifungal drug responses and host-pathogen interactions of the pathogenic mucoralean fungus Mucor circinelloides.
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Calcium-Mediated Induction of Paradoxical Growth following Caspofungin Treatment Is Associated with Calcineurin Activation and Phosphorylation in Aspergillus fumigatus.
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Candida guilliermondii, an opportunistic fungal pathogen with decreased susceptibility to fluconazole: geographic and temporal trends from the ARTEMIS DISK antifungal surveillance program.
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Caspofungin exposure alters the core septin AspB interactome of Aspergillus fumigatus.
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Caspofungin for invasive candidiasis at a tertiary care medical center.
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Caspofungin for the treatment of azole resistant candidemia in a premature infant.
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Caspofungin versus amphotericin B for invasive candidiasis.
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Caspofungin: first approved agent in a new class of antifungals.
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Cell wall integrity is dependent on the PKC1 signal transduction pathway in Cryptococcus neoformans.
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Cell-Penetrating Pepducin Therapy Targeting PAR1 in Subjects With Coronary Artery Disease.
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Cerebral phaeohyphomycosis in an immunodeficient child treated medically with combination antifungal therapy.
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Clinical research in the lay press: irresponsible journalism raises a huge dose of doubt.
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Commentary: pediatric antifungal drug development: lessons learned and recommendations for the future.
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Comparison of caspofungin and amphotericin B for invasive candidiasis.
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Correlation of MIC with outcome for Candida species tested against caspofungin, anidulafungin, and micafungin: analysis and proposal for interpretive MIC breakpoints.
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Cost savings with implementation of PNA FISH testing for identification of Candida albicans in blood cultures.
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Deficiency of MMP1a (Matrix Metalloprotease 1a) Collagenase Suppresses Development of Atherosclerosis in Mice: Translational Implications for Human Coronary Artery Disease.
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Differential effects of inhibiting chitin and 1,3-{beta}-D-glucan synthesis in ras and calcineurin mutants of Aspergillus fumigatus.
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Discovery of Antimicrobial Lipodepsipeptides Produced by a Serratia sp. within Mosquito Microbiomes.
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Echinocandins: role in antifungal therapy, 2005.
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Emerging echinocandins for treatment of invasive fungal infections.
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Fatal Scopulariopsis brevicaulis infection in a paediatric stem-cell transplant patient treated with voriconazole and caspofungin and a review of Scopulariopsis infections in immunocompromised patients.
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Global analysis of the evolution and mechanism of echinocandin resistance in Candida glabrata.
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Global distribution and outcomes for Candida species causing invasive candidiasis: results from an international randomized double-blind study of caspofungin versus amphotericin B for the treatment of invasive candidiasis.
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HIV-1 incorporation of host-cell-derived glycosphingolipid GM3 allows for capture by mature dendritic cells.
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Higher clearance of micafungin in neonates compared with adults: role of age-dependent micafungin serum binding.
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Hsp70 and the Cochaperone StiA (Hop) Orchestrate Hsp90-Mediated Caspofungin Tolerance in Aspergillus fumigatus.
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Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin.
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Identification of a key lysine residue in heat shock protein 90 required for azole and echinocandin resistance in Aspergillus fumigatus.
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In vitro antifungal activity of pneumocandin L-743,872 against a variety of clinically important molds.
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In vitro interactions between antifungals and immunosuppressants against Aspergillus fumigatus isolates from transplant and nontransplant patients.
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In vitro interactions between antifungals and immunosuppressants against Aspergillus fumigatus.
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In vitro investigation of the hepatobiliary disposition mechanisms of the antifungal agent micafungin in humans and rats.
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Initial characterization of micafungin pulmonary delivery via two different nebulizers and multivariate data analysis of aerosol mass distribution profiles.
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Interlaboratory comparison of results of susceptibility testing with caspofungin against Candida and Aspergillus species.
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Metal Chelation as a Powerful Strategy to Probe Cellular Circuitry Governing Fungal Drug Resistance and Morphogenesis.
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Micafungin: the US perspective.
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Native valve endocarditis due to Candida glabrata treated without valvular replacement: a potential role for caspofungin in the induction and maintenance treatment.
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Nebulizer delivery of micafungin aerosols.
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Noncanonical Matrix Metalloprotease 1-Protease-Activated Receptor 1 Signaling Drives Progression of Atherosclerosis.
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PAR1 (Protease-Activated Receptor 1) Pepducin Therapy Targeting Myocardial Necrosis in Coronary Artery Disease and Acute Coronary Syndrome Patients Undergoing Cardiac Catheterization: A Randomized, Placebo-Controlled, Phase 2 Study.
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Pharmacokinetic and maximum tolerated dose study of micafungin in combination with fluconazole versus fluconazole alone for prophylaxis of fungal infections in adult patients undergoing a bone marrow or peripheral stem cell transplant.
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Pharmacokinetics and Safety of Micafungin in Infants Supported With Extracorporeal Membrane Oxygenation.
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Pharmacokinetics of an elevated dosage of micafungin in premature neonates.
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Pharmacological resolution of a multiloculated Candida spp. liver abscess in a preterm neonate.
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Pimecrolimus enhances TLR2/6-induced expression of antimicrobial peptides in keratinocytes.
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Population pharmacokinetics of micafungin and its metabolites M1 and M5 in children and adolescents.
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Population pharmacokinetics of micafungin in neonates and young infants.
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Posaconazole exhibits in vitro and in vivo synergistic antifungal activity with caspofungin or FK506 against Candida albicans.
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Rational design of membrane proximal external region lipopeptides containing chemical modifications for HIV-1 vaccination.
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Safety and pharmacokinetics of repeat-dose micafungin in young infants.
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Safety of micafungin in infants: insights into optimal dosing.
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Scanning Quadrupole Data-Independent Acquisition, Part B: Application to the Analysis of the Calcineurin-Interacting Proteins during Treatment of Aspergillus fumigatus with Azole and Echinocandin Antifungal Drugs.
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Scedosporium prolificans osteomyelitis in an immunocompetent child treated with voriconazole and caspofungin, as well as locally applied polyhexamethylene biguanide.
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Short-term risk of liver and renal injury in hospitalized patients using micafungin: a multicentre cohort study.
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Successful medical treatment of cutaneous aspergillosis in a premature infant using liposomal amphotericin B, voriconazole and micafungin.
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Synergistic antifungal activities of bafilomycin A(1), fluconazole, and the pneumocandin MK-0991/caspofungin acetate (L-743,873) with calcineurin inhibitors FK506 and L-685,818 against Cryptococcus neoformans.
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The pharmacokinetics and pharmacodynamics of micafungin in experimental hematogenous Candida meningoencephalitis: implications for echinocandin therapy in neonates.
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Transcriptional regulation of chitin synthases by calcineurin controls paradoxical growth of Aspergillus fumigatus in response to caspofungin.
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Use of newer antifungal therapies in clinical practice: what do the data tell us?
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Keywords of People