SOXB1 Transcription Factors
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Subject Areas on Research
- A Novel Notch-YAP Circuit Drives Stemness and Tumorigenesis in Embryonal Rhabdomyosarcoma.
- CBX2 is required to stabilize the testis pathway by repressing Wnt signaling.
- Cell lineage mapping of taste bud cells and keratinocytes in the mouse tongue and soft palate.
- Comparison of reprogramming efficiency between transduction of reprogramming factors, cell-cell fusion, and cytoplast fusion.
- Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity.
- Differentiation of human embryonic stem cells along a hepatic lineage.
- Direct reprogramming of human fibroblasts into dopaminergic neuron-like cells.
- Evidence for type II cells as cells of origin of K-Ras-induced distal lung adenocarcinoma.
- Evidence that SOX2 overexpression is oncogenic in the lung.
- Familial recurrence of SOX2 anophthalmia syndrome: phenotypically normal mother with two affected daughters.
- Genetic correlates of insight in schizophrenia.
- Heme Oxygenase-1/Carbon Monoxide System and Embryonic Stem Cell Differentiation and Maturation into Cardiomyocytes.
- High-content imaging-based screening of microenvironment-induced changes to stem cells.
- Histologic pattern of invasion and epithelial-mesenchymal phenotype predict prognosis in squamous carcinoma of the head and neck.
- Identification of a novel epigenetic regulatory region within the pluripotency associated microRNA cluster, EEmiRC.
- Identification of novel mutations and sequence variants in the SOX2 and CHX10 genes in patients with anophthalmia/microphthalmia.
- LIN28B promotes the development of neuroendocrine prostate cancer.
- Loss of the tumor suppressor, Tp53, enhances the androgen receptor-mediated oncogenic transformation and tumor development in the mouse prostate.
- Mammalian genes induce partially reprogrammed pluripotent stem cells in non-mammalian vertebrate and invertebrate species.
- MicroRNA miR-590-5p inhibits breast cancer cell stemness and metastasis by targeting SOX2.
- Mitigating SOX2-potentiated Immune Escape of Head and Neck Squamous Cell Carcinoma with a STING-inducing Nanosatellite Vaccine.
- Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm.
- Multiple roles for Sox2 in the developing and adult mouse trachea.
- Personalized and targeted therapy of esophageal squamous cell carcinoma: an update.
- R-spondin1 tips the balance in sex determination.
- Rapid and Efficient Generation of Transgene-Free iPSC from a Small Volume of Cryopreserved Blood.
- Rare SOX2+ Airway Progenitor Cells Generate KRT5+ Cells that Repopulate Damaged Alveolar Parenchyma following Influenza Virus Infection.
- Reciprocal SOX2 regulation by SMAD1-SMAD3 is critical for anoikis resistance and metastasis in cancer.
- Regulation of glioblastoma stem cells by retinoic acid: role for Notch pathway inhibition.
- Regulation of male germ cell cycle arrest and differentiation by DND1 is modulated by genetic background.
- SOX2 expression is an early event in a murine model of EGFR mutant lung cancer and promotes proliferation of a subset of EGFR mutant lung adenocarcinoma cell lines.
- SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas.
- Selenium Augments microRNA Directed Reprogramming of Fibroblasts to Cardiomyocytes via Nanog.
- Sex determining region Y-Box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung.
- Sox2 cooperates with Lkb1 loss in a mouse model of squamous cell lung cancer.
- Sox2 cooperates with inflammation-mediated Stat3 activation in the malignant transformation of foregut basal progenitor cells.
- Sox2 expression in Schwann cells inhibits myelination in vivo and induces influx of macrophages to the nerve.
- Sox2 is required for development of taste bud sensory cells.
- Sox2 regulates cholinergic amacrine cell positioning and dendritic stratification in the retina.
- Targeting Hypoxia-Inducible Factor 1α in a New Orthotopic Model of Glioblastoma Recapitulating the Hypoxic Tumor Microenvironment.
- The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment.
- The cell of origin and subtype of K-Ras-induced lung tumors are modified by Notch and Sox2.
- eIF4E-phosphorylation-mediated Sox2 upregulation promotes pancreatic tumor cell repopulation after irradiation.
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Keywords of People
- Hogan, Brigid L. M., Research Professor of Cell Biology, Cell Biology