Halogenated Diphenyl Ethers

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  Subject Areas on Research

  • Accumulation and debromination of decabromodiphenyl ether (BDE-209) in juvenile fathead minnows (Pimephales promelas) induces thyroid disruption and liver alterations. 
  • Accumulation of PBDEs in stranded harp (Pagophilus groenlandicus) and hooded seals (Cystophora cristata) from the Northeastern United States. 
  • Aryl phosphate esters within a major PentaBDE replacement product induce cardiotoxicity in developing zebrafish embryos: potential role of the aryl hydrocarbon receptor. 
  • Associations between PBDEs in office air, dust, and surface wipes. 
  • Associations between brominated flame retardants in house dust and hormone levels in men. 
  • Associations between flame retardant applications in furniture foam, house dust levels, and residents' serum levels. 
  • Associations between polybrominated diphenyl ether (PBDE) flame retardants, phenolic metabolites, and thyroid hormones during pregnancy. 
  • Associations between serum levels of polybrominated diphenyl ether (PBDE) flame retardants and environmental and behavioral factors in pregnant women. 
  • Associations of birth outcomes with maternal polybrominated diphenyl ethers and thyroid hormones during pregnancy. 
  • BDE 49 and developmental toxicity in zebrafish. 
  • BDE99 (2,2',4,4',5-pentabromodiphenyl ether) suppresses differentiation into neurotransmitter phenotypes in PC12 cells. 
  • Brominated and organophosphate flame retardants target different neurodevelopmental stages, characterized with embryonic neural stem cells and neuronotypic PC12 cells. 
  • Brominated flame retardants in breast milk and behavioural and cognitive development at 36 months. 
  • Brominated flame retardants in placental tissues: associations with infant sex and thyroid hormone endpoints. 
  • Characterization of Individual Isopropylated and tert-Butylated Triarylphosphate (ITP and TBPP) Isomers in Several Commercial Flame Retardant Mixtures and House Dust Standard Reference Material SRM 2585. 
  • Characterizing the in vitro hepatic biotransformation of the flame retardant BDE 99 by common carp. 
  • Characterizing the peroxisome proliferator-activated receptor (PPARγ) ligand binding potential of several major flame retardants, their metabolites, and chemical mixtures in house dust. 
  • Comment on "Mutagenic Azo Dyes, Rather Than Flame Retardants, Are the Predominant Brominated Compounds in House Dust". 
  • Concentrations of polybrominated diphenyl ethers (PBDEs) and 2,4,6-tribromophenol in human placental tissues. 
  • Current-use flame retardants: Maternal exposure and neurodevelopment in children of the CHAMACOS cohort. 
  • Debromination of polybrominated diphenyl ether congeners BDE 99 and BDE 183 in the intestinal tract of the common carp (Cyprinus carpio). 
  • Debromination of polybrominated diphenyl ether-99 (BDE-99) in carp (Cyprinus carpio) microflora and microsomes. 
  • Debromination of the flame retardant decabromodiphenyl ether by juvenile carp (Cyprinus carpio) following dietary exposure. 
  • Demographic and dietary risk factors in relation to urinary metabolites of organophosphate flame retardants in toddlers. 
  • Developmental and behavioral effects of embryonic exposure to the polybrominated diphenylether mixture DE-71 in the killifish (Fundulus heteroclitus). 
  • Developmental exposure to low concentrations of two brominated flame retardants, BDE-47 and BDE-99, causes life-long behavioral alterations in zebrafish. 
  • Disruption of thyroid hormone sulfotransferase activity by brominated flame retardant chemicals in the human choriocarcinoma placenta cell line, BeWo. 
  • Disruption of type 2 iodothyronine deiodinase activity in cultured human glial cells by polybrominated diphenyl ethers. 
  • Do flame retardant chemicals increase the risk for thyroid dysregulation and cancer? 
  • Evaluating daily exposure to polychlorinated biphenyls and polybrominated diphenyl ethers in fish oil supplements. 
  • Evaluating the Use of Silicone Wristbands To Measure Personal Exposure to Brominated Flame Retardants. 
  • Evaluating the bioaccessibility of flame retardants in house dust using an in vitro Tenax bead-assisted sorptive physiologically based method. 
  • Exposure to PBDEs in the office environment: evaluating the relationships between dust, handwipes, and serum. 
  • Exposure to a PBDE/OH-BDE mixture alters juvenile zebrafish (Danio rerio) development. 
  • Exposure to flame retardant chemicals and occurrence and severity of papillary thyroid cancer: A case-control study. 
  • Exposures, mechanisms, and impacts of endocrine-active flame retardants. 
  • Fate of flame retardants and the antimicrobial agent triclosan in planted and unplanted biosolid-amended soils. 
  • Flame retardant associations between children's handwipes and house dust. 
  • Flame retardant exposure among collegiate United States gymnasts. 
  • Flame retardant exposure assessment: findings from a behavioral intervention study. 
  • Flame retardants and their metabolites in the homes and urine of pregnant women residing in California (the CHAMACOS cohort). 
  • Halogenated phenolic contaminants inhibit the in vitro activity of the thyroid-regulating deiodinases in human liver. 
  • Human exposure assessment of indoor dust: Webster and Stapleton respond. 
  • Identifying transfer mechanisms and sources of decabromodiphenyl ether (BDE 209) in indoor environments using environmental forensic microscopy. 
  • In vitro hepatic metabolism of 2,2',4,4',5-pentabromodiphenyl ether (BDE 99) in Chinook salmon (Onchorhynchus tshawytscha). 
  • In vitro metabolism of the brominated flame retardants 2-ethylhexyl-2,3,4,5-tetrabromobenzoate (TBB) and bis(2-ethylhexyl) 2,3,4,5-tetrabromophthalate (TBPH) in human and rat tissues. 
  • In vivo and in vitro debromination of decabromodiphenyl ether (BDE 209) by juvenile rainbow trout and common carp. 
  • Increased coiling frequency linked to apoptosis in the brain and altered thyroid signaling in zebrafish embryos (Danio rerio) exposed to the PBDE metabolite 6-OH-BDE-47. 
  • Inhibition of thyroid hormone sulfotransferase activity by brominated flame retardants and halogenated phenolics. 
  • Intervention to reduce gymnast exposure to flame retardants from pit foam: A case study. 
  • Lactational exposure to polybrominated diphenyl ethers and its relation to social and emotional development among toddlers. 
  • Linking PBDEs in house dust to consumer products using X-ray fluorescence. 
  • Low level exposure to the flame retardant BDE-209 reduces thyroid hormone levels and disrupts thyroid signaling in fathead minnows. 
  • Measurement of flame retardants and triclosan in municipal sewage sludge and biosolids. 
  • Measurement of polybrominated diphenyl ethers on hand wipes: estimating exposure from hand-to-mouth contact. 
  • Metabolism of polybrominated diphenyl ethers (PBDEs) by human hepatocytes in vitro. 
  • Metabolites of organophosphate flame retardants and 2-ethylhexyl tetrabromobenzoate in urine from paired mothers and toddlers. 
  • Novel and high volume use flame retardants in US couches reflective of the 2005 PentaBDE phase out. 
  • Occurrence of contaminants of emerging concern in mussels (Mytilus spp.) along the California coast and the influence of land use, storm water discharge, and treated wastewater effluent. 
  • PBDEs Concentrate in the Fetal Portion of the Placenta: Implications for Thyroid Hormone Dysregulation. 
  • PBDEs, methoxylated PBDEs and HBCDs in Japanese common squid (Todarodes pacificus) from Korean offshore waters. 
  • Persisting effects of a PBDE metabolite, 6-OH-BDE-47, on larval and juvenile zebrafish swimming behavior. 
  • Personal exposure to polybrominated diphenyl ethers (PBDEs) in residential indoor air. 
  • Photodegradation of decabromodiphenyl ether in house dust by natural sunlight. 
  • Photodegradation pathways of nonabrominated diphenyl ethers, 2-ethylhexyltetrabromobenzoate and di(2-ethylhexyl)tetrabromophthalate: identifying potential markers of photodegradation. 
  • Polybrominated diphenyl ethers in house dust and clothes dryer lint. 
  • Relationships between polybrominated diphenyl ether concentrations in house dust and serum. 
  • Results from Screening Polyurethane Foam Based Consumer Products for Flame Retardant Chemicals: Assessing Impacts on the Change in the Furniture Flammability Standards. 
  • Rodent thyroid, liver, and fetal testis toxicity of the monoester metabolite of bis-(2-ethylhexyl) tetrabromophthalate (tbph), a novel brominated flame retardant present in indoor dust. 
  • Serum PBDEs in a North Carolina toddler cohort: associations with handwipes, house dust, and socioeconomic variables. 
  • Species-specific differences and structure-activity relationships in the debromination of PBDE congeners in three fish species. 
  • The Affinity of Brominated Phenolic Compounds for Human and Zebrafish Thyroid Receptor β: Influence of Chemical Structure. 
  • Toward fire safety without chemical risk. 
  • Urinary biomarkers of flame retardant exposure among collegiate U.S. gymnasts. 
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  Keywords of People

  • Ferguson, P. Lee, Associate Professor of Civil and Environmental Engineering, Civil and Environmental Engineering