Pelvic Organ Prolapse

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  Subject Areas on Research

  • A model for predicting the risk of de novo stress urinary incontinence in women undergoing pelvic organ prolapse surgery. 
  • American Urogynecologic Society Prolapse Consensus Conference Summary Report. 
  • Assessing pelvic organ prolapse recurrence after minimally invasive sacrocolpopexy: does mesh weight matter? 
  • Attitudes toward hysterectomy in women undergoing evaluation for uterovaginal prolapse. 
  • Bacterial uropathogens and antibiotic susceptibility of positive urine cultures in women with pelvic organ prolapse and urinary incontinence. 
  • Bowel function, sexual function, and symptoms of pelvic organ prolapse in women with and without urinary incontinence. 
  • Changes in Performance of Apical Suspension at the Time of Surgery for Prolapse: Assessment of the Influence of the American Urogynecologic Society and American College of Obstetricians and Gynecologists Practice Bulletin. 
  • Characterizing the phenotype of advanced pelvic organ prolapse. 
  • Comprehensive analysis of LAMC1 genetic variants in advanced pelvic organ prolapse. 
  • Concomitant Anterior Repair, Preoperative Prolapse Severity, and Anatomic Prolapse Outcomes After Vaginal Apical Procedures. 
  • Cost-minimization analysis of robotic-assisted, laparoscopic, and abdominal sacrocolpopexy. 
  • Deciding Our Future: Consensus Conference Summary Report. 
  • Design of a 3-Arm Randomized Trial for Posthysterectomy Vault Prolapse Involving Sacral Colpopexy, Transvaginal Mesh, and Native Tissue Apical Repair: The Apical Suspension Repair for Vault Prolapse in a Three-Arm Randomized Trial. 
  • Design of a Study to Measure Patient-Perspectives in Adverse Event Reporting (the PPAR Study): Supplementary Study to the ASPIRe Trial. 
  • Development and Validation of a Quantitative Measure of Adaptive Behaviors in Women With Pelvic Floor Disorders. 
  • Diagnosis and Management of Postpartum Pelvic Floor Disorders. 
  • Do Mixed-Flora Preoperative Urine Cultures Matter? 
  • Does Mesh Weight Affect Time to Failure After Robotic-Assisted Laparoscopic Sacrocolpopexy? 
  • Does concomitant anterior/apical repair during midurethral sling improve the overactive bladder component of mixed incontinence? 
  • Effect of Uterosacral Ligament Suspension vs Sacrospinous Ligament Fixation With or Without Perioperative Behavioral Therapy for Pelvic Organ Vaginal Prolapse on Surgical Outcomes and Prolapse Symptoms at 5 Years in the OPTIMAL Randomized Clinical Trial. 
  • Forecasting the prevalence of pelvic floor disorders in U.S. Women: 2010 to 2050. 
  • Further validation of the short form versions of the Pelvic Floor Distress Inventory (PFDI) and Pelvic Floor Impact Questionnaire (PFIQ). 
  • Future Directions of Research and Care for Urinary Incontinence: Findings from the National Institute of Diabetes and Digestive and Kidney Diseases Summit on Urinary Incontinence Clinical Research in Women. 
  • How does site of pelvic organ prolapse repair affect overactive bladder symptoms? 
  • Immediate Postoperative Pelvic Organ Prolapse Quantification Measures and 2-Year Risk of Prolapse Recurrence. 
  • Impact of Genital Hiatus Size on Anatomic Outcomes After Mesh-Augmented Sacrospinous Ligament Fixation. 
  • Impact of Repeat Dosing and Mesh Exposure Chronicity on Exosome-Induced Vaginal Tissue Regeneration in a Porcine Mesh Exposure Model. 
  • Incidence of adverse events after uterosacral colpopexy for uterovaginal and posthysterectomy vault prolapse. 
  • Is postoperative bowel function related to posterior compartment prolapse repair? 
  • Long-Term Effectiveness of Uterosacral Colpopexy and Minimally Invasive Sacral Colpopexy for Treatment of Pelvic Organ Prolapse. 
  • Long-term Urinary Outcomes After Transvaginal Uterovaginal Prolapse Repair With and Without Concomitant Midurethral Slings. 
  • Long-term outcomes following abdominal sacrocolpopexy for pelvic organ prolapse. 
  • Lower abdominal and pelvic pain with advanced pelvic organ prolapse: a case-control study. 
  • Management of Vaginal Mesh Exposures Following Female Pelvic Reconstructive Surgery. 
  • Management of advanced prolapse including a bowel obstruction: expanding the role of transvaginal surgery. 
  • Matrix metalloproteinase-9 genetic polymorphisms and the risk for advanced pelvic organ prolapse. 
  • Mesh sacrocolpopexy compared with native tissue vaginal repair: a systematic review and meta-analysis. 
  • Methods for the defining mechanisms of anterior vaginal wall descent (DEMAND) study. 
  • Models for Predicting Recurrence, Complications, and Health Status in Women After Pelvic Organ Prolapse Surgery. 
  • Neural entrapment during uterosacral ligament suspension: an anatomic study of female cadavers. 
  • Open sacrocolpopexy and vaginal apical repair: retrospective comparison of success and serious complications. 
  • Operations and pelvic muscle training in the management of apical support loss (OPTIMAL) trial: design and methods. 
  • Oral antibiotics to prevent postoperative urinary tract infection: a randomized controlled trial. 
  • Outcomes of native tissue transvaginal apical approaches in women with advanced pelvic organ prolapse and stress urinary incontinence. 
  • Pain and activity after vaginal reconstructive surgery for pelvic organ prolapse and stress urinary incontinence. 
  • Pelvic Floor Disorders Registry: Study Design and Outcome Measures. 
  • Pelvic floor symptoms improve similarly after pessary and behavioral treatment for stress incontinence. 
  • Perioperative Behavioral Therapy and Pelvic Muscle Strengthening Do Not Enhance Quality of Life After Pelvic Surgery: Secondary Report of a Randomized Controlled Trial. 
  • Perioperative Complications in Minimally Invasive Sacrocolpopexy Versus Transvaginal Mesh in the Management of Pelvic Organ Prolapse: Analysis of a National Multi-institutional Dataset. 
  • Perioperative adverse events after minimally invasive abdominal sacrocolpopexy. 
  • Phenotyping clinical disorders: lessons learned from pelvic organ prolapse. 
  • Polyethylene Glycol 3350 and Docusate Sodium Compared With Docusate Sodium Alone After Urogynecologic Surgery: A Randomized Controlled Trial. 
  • Predicting the number of women who will undergo incontinence and prolapse surgery, 2010 to 2050. 
  • Predicting urinary incontinence after surgery for pelvic organ prolapse. 
  • Quantification of vaginal support: are continuous summary scores better than POPQ stage? 
  • Responsiveness and minimally important difference of SF-6D and EQ-5D utility scores for the treatment of pelvic organ prolapse. 
  • Risk Factors for Surgical Failure and Worsening Pelvic Floor Symptoms Within 5 Years After Vaginal Prolapse Repair. 
  • Robotic-assisted sacrocolpopexy: early postoperative outcomes after surgical reduction of enlarged genital hiatus. 
  • Sexual activity and vaginal topography in women with symptomatic pelvic floor disorders. 
  • Sexual function after vaginal versus nonvaginal prolapse surgery. 
  • Subgroups of failure after surgery for pelvic organ prolapse and associations with quality of life outcomes: a longitudinal cluster analysis. 
  • Success and failure are dynamic, recurrent event states after surgical treatment for pelvic organ prolapse. 
  • Summary: 2017 International Consultation on Incontinence Evidence-Based Surgical Pathway for Pelvic Organ Prolapse. 
  • Surgical Alteration of Genital Hiatus Size and Anatomic Failure After Vaginal Vault Suspension. 
  • Surgical management of pelvic organ prolapse. 
  • Symptomatic and anatomic 1-year outcomes after robotic and abdominal sacrocolpopexy. 
  • Teaching learners to raise the roof: a vaginal surgery simulator for apical suspension. 
  • Teaching the art of LeFort colpocleisis: a moderate-fidelity, low-cost simulation model. 
  • The Design of a Prospective Trial to Evaluate the Role of Preoperative Frailty Assessment in Older Women Undergoing Surgery for the Treatment of Pelvic Organ Prolapse: The FASt Supplemental Trial. 
  • The Evaluation of Baseline Physical Function and Cognition in Women Undergoing Pelvic Floor Surgery. 
  • The Patient Acceptable Symptom State in Female Urinary Incontinence. 
  • The Pelvic Floor Disorders Registry: Purpose and Development. 
  • The impossible voyage. 
  • Tissue remodeling in the female reproductive tract--a complex process becomes more complex: the role of Hox genes. 
  • Trends in use of surgical mesh for pelvic organ prolapse. 
  • Urinary basement membrane graft-augmented sacrospinous ligament suspension: a description of technique and short-term outcomes. 
  • Vaginal Uterosacral Ligament Suspension: A Retrospective Cohort of Absorbable and Permanent Suture Groups. 
  • Vaginal native tissue repair versus transvaginal mesh repair for apical prolapse: how utilizing different methods of analysis affects the estimated trade-off between reoperation for mesh exposure/erosion and reoperation for recurrent prolapse. 
  • Validation of a Model Predicting De Novo Stress Urinary Incontinence in Women Undergoing Pelvic Organ Prolapse Surgery. 
  • What happens to the posterior compartment and bowel symptoms after sacrocolpopexy? evaluation of 5-year outcomes from E-CARE. 
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  Keywords of People

  • Amundsen, Cindy Louise, Roy T. Parker, M.D. Distinguished Professor of Obstetrics and Gynecology, in the School of Medicine, Surgery, Urology
  • Jelovsek, John E, Professor of Obstetrics and Gynecology, Obstetrics and Gynecology, Urogynecology
  • Kisby, Cassandra K, Assistant Professor of Obstetrics and Gynecology, Duke Women's Health Holly Springs
  • Visco, Anthony Gabriele, Professor of Obstetrics and Gynecology, Obstetrics and Gynecology
  • Weidner, Alison Catherine, Professor of Obstetrics and Gynecology, Obstetrics and Gynecology, Urogynecology