Period Circadian Proteins

• 

  Subject Areas on Research

  • A Period2 Phosphoswitch Regulates and Temperature Compensates Circadian Period. 
  • An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome. 
  • An opposite role for tau in circadian rhythms revealed by mathematical modeling. 
  • CK1δ/ε protein kinase primes the PER2 circadian phosphoswitch. 
  • Casein kinase I in the mammalian circadian clock. 
  • Control of mammalian circadian rhythm by CKIepsilon-regulated proteasome-mediated PER2 degradation. 
  • Human casein kinase Idelta phosphorylation of human circadian clock proteins period 1 and 2. 
  • MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells. 
  • Mutation of a PER2 phosphodegron perturbs the circadian phosphoswitch. 
  • Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I epsilon. 
  • Nuclear export of mammalian PERIOD proteins. 
  • Phosphorylation and destabilization of human period I clock protein by human casein kinase I epsilon. 
  • Protein phosphatase 1 regulates the stability of the circadian protein PER2. 
  • Reversible protein phosphorylation regulates circadian rhythms. 
  • Role of mouse cryptochrome blue-light photoreceptor in circadian photoresponses. 
  • Setting clock speed in mammals: the CK1 epsilon tau mutation in mice accelerates circadian pacemakers by selectively destabilizing PERIOD proteins. 
  • Site-specific phosphorylation of casein kinase 1 δ (CK1δ) regulates its activity towards the circadian regulator PER2. 
  • The hypersensitive glucocorticoid response specifically regulates period 1 and expression of circadian genes. 
  • The phosphorylation switch that regulates ticking of the circadian clock. 
  • The role of polymorphisms in circadian pathway genes in breast tumorigenesis.