Co-Repressor Proteins

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  Subject Areas on Research

  • Altered telomeres in tumors with ATRX and DAXX mutations. 
  • DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors. 
  • Effects of rearrangement and allelic exclusion of JJAZ1/SUZ12 on cell proliferation and survival. 
  • Frequent fusion of the JAZF1 and JJAZ1 genes in endometrial stromal tumors. 
  • Molecular analysis of the JAZF1-JJAZ1 gene fusion by RT-PCR and fluorescence in situ hybridization in endometrial stromal neoplasms. 
  • Novel repression of Kcc2 transcription by REST-RE-1 controls developmental switch in neuronal chloride. 
  • Role of co-regulators in metabolic and transcriptional actions of thyroid hormone. 
  • SMRTER, a Drosophila nuclear receptor coregulator, reveals that EcR-mediated repression is critical for development. 
  • Somatic mutations in the transcriptional corepressor gene BCORL1 in adult acute myelogenous leukemia. 
  • The GRAS gene family in Arabidopsis: sequence characterization and basic expression analysis of the SCARECROW-LIKE genes. 
  • The glucocorticoid receptor interacting protein 1 (GRIP1) localizes in discrete nuclear foci that associate with ND10 bodies and are enriched in components of the 26S proteasome. 
  • The in vivo role of nuclear receptor corepressors in thyroid hormone action. 
  • Thermodynamic characterization of the binding interaction between the histone demethylase LSD1/KDM1 and CoREST. 
  • Thyroid hormone signaling in vivo requires a balance between coactivators and corepressors.