Nuclear Receptor Subfamily 1, Group F, Member 3
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Subject Areas on Research
- A validated regulatory network for Th17 cell specification.
- Cutting Edge: c-Maf Is Required for Regulatory T Cells To Adopt RORγt+ and Follicular Phenotypes.
- Diacylglycerol kinase zeta positively controls the development of iNKT-17 cells.
- Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity.
- Down-regulation of the orphan nuclear receptor ROR gamma t is essential for T lymphocyte maturation.
- G-CSF induces a potentially tolerant gene and immunophenotype profile in T cells in vivo.
- IFN-beta inhibits human Th17 cell differentiation.
- Inhibition of the transcription factor ROR-γ reduces pathogenic Th17 cells in acetylcholine receptor antibody positive myasthenia gravis.
- Lymphocyte accumulation in the spleen of retinoic acid receptor-related orphan receptor gamma-deficient mice.
- Multiple constraints at the level of TCRalpha rearrangement impact Valpha14i NKT cell development.
- Novel antigen-presenting cell imparts Treg-dependent tolerance to gut microbiota.
- Orphan nuclear receptors in T lymphocyte development.
- RORgamma t, a novel isoform of an orphan receptor, negatively regulates Fas ligand expression and IL-2 production in T cells.
- Regulation of the TCRalpha repertoire by the survival window of CD4(+)CD8(+) thymocytes.
- Retinoid-related orphan receptor gamma (RORgamma) is essential for lymphoid organogenesis and controls apoptosis during thymopoiesis.
- Selective LXXLL peptides antagonize transcriptional activation by the retinoid-related orphan receptor RORgamma.
- The role of orphan nuclear receptor in thymocyte differentiation and lymphoid organ development.
- The roles of orphan nuclear receptors in the development and function of the immune system.
- The transcription factor c-Maf is essential for the commitment of IL-17-producing γδ T cells.
- c-Maf regulates the plasticity of group 3 innate lymphoid cells by restraining the type 1 program.
- iNKT cells require TSC1 for terminal maturation and effector lineage fate decisions.
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Keywords of People
- Ciofani, Maria, Associate Professor of Integrative Immunobiology, Cell Biology