Claudins

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  Subject Areas on Research

  • A genome-wide association study of corneal astigmatism: The CREAM Consortium. 
  • Cell-cell adhesions and cell contractility are upregulated upon desmosome disruption. 
  • Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. 
  • Different mechanisms preclude mutant CLDN14 proteins from forming tight junctions in vitro. 
  • Distribution of the tight junction proteins ZO-1, occludin, and claudin-4, -8, and -12 in bladder epithelium. 
  • GUCY2C opposes systemic genotoxic tumorigenesis by regulating AKT-dependent intestinal barrier integrity. 
  • Genetic control of single lumen formation in the zebrafish gut. 
  • Molecular staging of epithelial maturation using secretory cell-specific genes as markers. 
  • Regulation of intrahepatic biliary duct morphogenesis by Claudin 15-like b. 
  • Sex-specific genetic predictors of Alzheimer's disease biomarkers. 
  • Targeted suppression of claudin-5 decreases cerebral oedema and improves cognitive outcome following traumatic brain injury.